• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2018년도 춘계학술대회
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• pp.188-192
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• 2018

대뇌혈류를 증가 시키는 수술은 뇌경색의 치료방법중 하나이다. 그러나 수술과 같은 침습적인 방법은 환자에게 수술 후유증 또는 부작용을 부담하게 한다. 이러한 침습적인 방법을 보완하기 위해 사람의 혈압을 이용해, 사지에 압박을 가하여 대뇌 혈류를 증가 시키는 비 침습적인 장치도 등장하였다. 그러나 속도와 정확성이 떨어지는 문제점이 제기되었다. 본 논문에서는, 정확한 측정과 측정하는 데에 걸리는 시간을 기존의 장치보다 개선하기 위해, Blood Oxygen Level Sensor를 이용하여, 양팔에 압력을 주면서 각 팔의 Perfusion Index를 측정하여, Perfusion Index가 일정 값 이하로 떨어지는 순간의 75% 압력을 팔에 가하고, 다리에는 팔에서 구해진 압력 값을 이용해 계산하여 얻은 압력을 가한다. 기존의 혈압 측정식 대뇌혈류증가 장치와 같이, 혈류량을 20%이상 증가시킬 수 있고, 또한 측정 시간도 단축한 결과를 얻어 뇌경색 환자에게 선택적으로 사용할 수 있다.

• 대한의용생체공학회:의공학회지
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• 제27권3호
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• pp.89-93
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• 2006

A simple algorithm that can be used to estimate a healthy person's blood pressure using pulse transit time is proposed in this paper. Fifty healthy students participated in the experiment that was conducted in line with the study. The subjects were asked to exercise on several exercise levels using a bicycle ergometer. Their blood pressures during the succeeding rest period were measured. A simple method was proposed to illustrate the relationship between blood pressure and pulse transit time. The systolic blood pressures as well as the heights and weights of the subjects were regarded as the proper parameters, and a second-order regression curve was produced to estimate the subjects' blood pressures. The mean error of estimation was less than 10 mmHg, which was the mean error of manual measurement. Although our estimation model is so simple, it can be used to estimate continuous blood pressure measurement for bicycle ergometer exercise. The electrocardiograms, photoplethysmograms, and blood pressures, however, could not be measured simultaneously As such, their estimation may be slightly different from the results taken from simultaneous measurements.

• 한국농촌생활과학회지
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• 제7권1호
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• pp.23-29
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• 1996

The purpose of this study is to observe the relationship between smoking and control factors to blood pressure, such as sodium and potassium levels of dietary intake and serum in 67 rural university male students(smoker: 35 persons, non smoker: 32 persons). 3-day dietary record and blood sampling were conducted for measurements of the levels of dietary intake and serum. The results were as follows: 1) There are no significance between smokers and non-smokers in height, weight, and BMI. 2) Mean systolic and diastolic blood pressure of smokers and non-smokers were $131.33\pm93.75mmHg, \;119.37\pm80.62mmHg, $ respectively. Blood pressure of smoker was higher than that of non-smokers(p＜0.05). 3) There was no significant difference between smoker and non smoker in dietary potassium intake but dietary sodium intake and Na/K ratio of smoker were higher than those of non-smokers(p＜0.05, p＜0.05). And significant correlation was found between dietary sodium intake and blood pressure of smokers(p＜0.05). 4) Smokers of optimum gustation of salt(0.52%) was higher than that of non-smokers(0.49%). Even though blood pressure of smokers was not critical level, if they smoke continuosely until middle age, their blood pressure will be increased by smoking. The results of this study suggest that no smoking education program for smokers including the information about desirable food habits for prevention of hypertension should be developed.

• 대한한의학회지
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• 제21권1호
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• pp.62-67
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• 2000

Background and Purpose: Sybsun-points are located at the tips of all fingers, 0.1chon from the finger nails, totaling 10 points on both hands. These points have been used for emergency care, fainting, epilepsy, cerebrovascular accidents, hypertension, unconsciousness, high fever etc. The most common technique is bleeding with a needle at these points. Hypertension and fever are the main factors for stroke patients’progress. We investigated whether venesection at Sybsun-points has effects on blood pressure and body temperature in stroke patients. Materials and Methods: 79 stroke patients were enrolled in this study from 1 Jan. 1999 to 30 Sep. 1999. All of them were admitted in Kyunghee University, Hospital of Oriental Medicine. Among them, 62 patients were hypertensive people, 17 were normal. Among the hypertensive patients, 27 were stage 1,20 were stage 2, 15 were stage 3 by classification of JNC 1997. All of the hypertensive patients had been taking drugs, while the normal group did not. From 2pm to 3pm, every 30 minutes we checked patients' blood pressure and body temperature by 24ABPM and tympanic thermometer. After 30 minutes passed, we phlebotomized patients Sybsun-points with Samneung needle 2-3cc of blood. Right after the bleeding, we checked blood pressure and body temperature. After the bleeding, for the next hour and a half, we checked each patient’s blood pressure and body temperature every thirty minutes, or a total of three times. We compared the blood pressure and the body temperature before and after treatment(p<0.05). Results: 1. Venesection at Sybsun-points significantly decreased systolic blood pressure on stage 3 hypertensive patients(p<0.0l). 2. Venesection at Sybsun-points significantly decreased diastolic blood pressure on stage 3 hypertensive patients(p<0.05) 3. Venesection at Sybsun-points had no effect on the change of body temperature. Conclusions: Though further study is needed, our findings suggest that Venesection at Sybsun-points may alleviate hypertension in stroke patients.

• 대한약침학회지
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• 제26권4호
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• pp.298-306
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• 2023

Objectives: Cucumis sativus L. (C. sativus) is vegetable commonly used for managing blood pressure and often consumed in combination with standard antihypertensive therapy, despite lack of scientific evidence supporting their use. Combination of herbs and standard medication could have positive or negative effects. Therefore, this study aimed to evaluate the antihypertensive activity of C. sativus and the combined effect with losartan in the hypertensive rat model induced by angiotensin II. Angiotensin II is a component of the renin-angiotensin-aldosterone system that, upon binding to its receptor, constricts blood vessels leading to elevation of blood pressure. Methods: In an antihypertensive study, rats received C. sativus orally at doses of 9, 18, 27, and 36 mg/kg (full dose); while in a combination study, animals received losartan 2.25 mg/kg combined by either with C. sativus 9 or 18 mg/kg. The standards group received losartan 2.25 mg/kg or 4.5 mg/kg (full dose). Results: Blood pressure was measured using the tail-cuff method. C. sativus significantly attenuated angiotensin II-induced hypertension as observed in groups receiving C. sativus at 9, 18, 27, and 36 mg/kg at 30 minutes after induction showed the average change (Δ) of systolic blood pressure (SBP) and diastolic blood pressure (DBP) with respect to time zero were 28.8/18.3, 24.8/15.8, 22.8/15.5, and 11.5/9.0 mmHg, respectively. Whereas the average change (Δ) of SBP and DBP in the rats receiving the combination of half doses of C. sativus and losartan were 8.8/9.0 mmHg, respectively. These diminished effects were better than a full dose of C. sativus and comparable with a full dose of losartan (6.5/7.8 mmHg). Conclusion: The present findings indicate that C. sativus dose-dependently blocks blood pressure elevation induced by angiotensin II. The combination of half dose of C. sativus and losartan has an additive effect in lowering blood pressure.

• International Journal of Control, Automation, and Systems
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• 제2권1호
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• pp.39-54
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• 2004

We developed an automatic blood pressure control system to maintain the blood pressure of patients at a substantially low level during a surgical operation. The developed system discharges two functions, continuous feedback control of the mean arterial pressure (MAP) by a state-predictive servo controller and risk control based on the inference by fuzzy-like logics and rules using measured data. Twenty-eight clinical applications were made beginning in November 1995, and the effects of the automatic blood pressure control on the operation time and on bleeding were assessed affirmatively by means of Wilcoxon testing. This paper essentially reports the engineering details of the control system.

• 한국임상수의학회지
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• 제16권2호
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• pp.253-256
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• 1999

The influence of essential oils from aboriginal softwoods as Pinus densiflora, Pinus koraiensis, Chamaecyparis obtusa and Chamaecyparis pisifera on the motor coordination, pulse, mean blood artery pressure and pain reducing test was investigated in mice and rats. The motor coordination of mouse was not induced by the inhalation of each oil. Furthermore, these oils did not alter the changes of the mean blood pressure and pulse rate. Chamaecyparis pisifera trand to reduce the mean blood pressure. The abdominal pain induced by acetic acid was reduced only by an essential oil from Pinus koraiensis in mouse.

• 한국임상수의학회지
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• 제20권2호
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• pp.224-228
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• 2003

This study was performed to evaluate the effect of electroacupuncture at some acupoint combinations on the cardiovascular system, especially on blood pressure. Electroacupuncture at acupoint combinations of CV2O(+)/GV-16(-),4(+)/GV16(-), KI1(+)/GV20(-), and HT9(+)/GV16(-) did not changed heart rates and blood pressure, but stimulation of HT1(+)/HT7(-) Increased systolic, diastolic and mean arterial blood pressure significantly in dogs anesthetized with tiletamine/zolazepam.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1991년도 추계학술대회
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• pp.113-118
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• 1991

Hypertension is a medical problem with no permanent cure. Extended hypertension can cause various cardio vascular diseases, cerebral vascular diseases, and circulatory system trouble. Medical treatment at present does not consider circadian variation of blood pressure in patients ; therefore, the problem of over-reduction of blood pressure through drugs sometimes occurs. This paper presents a prediction model of circadian variation or moon blood pressure employing the endocrine grand and the autonomic nervous system.

• 대한한방내과학회지
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• 제18권2호
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• pp.151-159
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• 1997

Fructus Tribuli has been used in Korea for many centuries as a therapeutic agent for headache and dizziness due to hyperactivity of the liver-yang. The effect of Fructus Tribuli on the blood pressure is not known. The purpose of this study was to determine the effect of Fructus Tribuli on blood pressure and artery rats and rabbits. 1. Fructus Tribuli exerted a dose-dependent relaxation of isolated rabbit common carotid artery. 2. Blood pressure was significantly decreased by Fructus Tribuli (10.0mg/kg) in rats.