• Title/Summary/Keyword: Blood Groups

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Effects of Turmeric (Curcuma longa L.) on Blood Glucose and Lipid Metabolism Functional Improvement in STZ-induced Diabetic rats (울금(Curcuma longa L.) 섭취가 당뇨성 흰쥐의 혈당 및 지질대사 기능 개선에 미치는 영향)

  • Oh, Da-Young;Kang, Dong-Soo;Lee, Young-Geun;Kim, Han-Soo
    • Journal of Environmental Science International
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    • v.28 no.5
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    • pp.485-494
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    • 2019
  • The purpose of this study was to investigate the improvement effect of 5% turmeric (Curcuma longa L.) on the blood glucose and lipid metabolism function of streptozotocin (STZ, 45 mg/kg body weight)-induced diabetic rats. Seven-week-old male rats were divided into four groups (n=6), and fed experimental diets containing turmeric meal [basal diet+5% turmeric (BT), basal diet+STZ+5% turmeric (ST)], and control (BD), BS groups (basal diet+STZ). The results of this study, turmeric diet groups (BT, ST) in lipid component as evidenced from the significantly reduction of serum total cholesterol, low density lipoprotein-cholesterol (LDL-cholesterol), atherosclerotic index (AI), cardiac risk factor (CRF), triglyceride (TG), phospholipid (PL), free cholesterol, cholesteryl ester, uric acid, blood glucose, non esterified fatty acid (NEFA), and elevation of high density lipoprotein-cholesterol (HDL-cholesterol). The serum albumin and globulin contents were increased in turmeric supplementation diet than STZ-induced diabetic rats (p<0.05). Concentrations of sodium (Na) and chlorine (Cl) in sera were lower in the turmeric diet than diabetic group. Total calcium (T-Ca), phosphorus (Pi) and potassium (K) concentrations in sera were higher in the BT, ST and BD groups than BS group. In vivo experiments with Sprague-Dawley rats showed that ingestion of turmeric (Curcuma longa L.) were effective in the blood glucose and lipid metabolism functional improvement.

Effects on hematology and blood biochemistry profile of intramuscular meloxicam injection in Brahminy kite and Barn owl

  • Ratiwan Sitdhibutr;Raveewan Ploypan;Sirawit Subaneg;Chaiyan Kasorndorkbua
    • Journal of Veterinary Science
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    • v.24 no.3
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    • pp.43.1-43.8
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    • 2023
  • Background: Meloxicam is used widely for exotic animal analgesia, but its toxicity in common raptor species in Thailand is unclear. Objectives: This study evaluated the single-dose effect of intramuscular meloxicam in common raptor species in Thailand for short-term and long-term periods. Methods: Twenty-two raptors were administered a single 1 mg/kg dose of meloxicam individually via intramuscular injection. The following were evaluated: clinical appearance, body weight, body condition score, body temperature, fecal appearance, complete blood cell count, and biochemistry panel before (day 0) and after the injection (1, 7, and 30 days). The collected samples were categorized into three groups: Brahminy kite (Haliastur indus) (n = 10), adult Barn owl (Tyto javanica) (n = 4), and juvenile Barn owl (n = 8). Results: None of the raptors in the study groups showed any abnormalities. The hematological profiles were significantly different in the short-term period (day 1 and day 7). The creatinine, aspartate aminotransferase, and creatinine kinase increased in several groups. On the other hand, the packed cell volume decreased in the Brahminy kite and juvenile Barn owl groups. According to the findings, an intramuscular injection of 1 mg/kg meloxicam affected the blood biochemistry panel of the muscle, but the affected raptors recovered within one week. Conclusions: An intramuscular injection of meloxicam at a single 1 mg/kg dose in Brahminy kites and Barn owls was not associated with the morbidity, hepatotoxicity, gastrointestinal toxicity, and nephrotoxicity in the short- and long-term periods.

The Experimental Study of Myocardial Protection Byusing Cold Blood Potassium Cardioplegia in Open Heart Surgery (냉혈 Potassium 심정지액을 이용한 심근보호의 실험적 연구)

  • 이동준
    • Journal of Chest Surgery
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    • v.13 no.3
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    • pp.186-197
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    • 1980
  • We attempted to evaluate the effectiveness of cold blood potassium cardioplegia [Group B] compared with that of intermittent aortic cross clamp with topical hypothermia [Group A] in each six dogs. The studies were performed under the extracorporeal circulation with moderate hypothermia by using Mongrel dogs. 1. In Group A [6], it was difficult to maintain the temperature below 20?. but in Group B [6], it was possible to maintain the temperature. 2. In blood pressure and myocardial recovery ability, Group B was more excellent than Group A. 3. There was no significant difference in Na+, Ca++ and Cl- between both groups, but in K+ level, Group A was mild decreased and Group B was nearly normal level. 4. In serum LDH level, Group A was higher than Group B, but in SGOT level there was no significance between both groups. 5. On electromicroscopical study, Group A showed severe change in mitochondria, but Group B was nearly normal view. Thus we suggest that cold blood potassium cardioplegia would be more effective than intermittent aortic cross clamp with topical hypothermia for myocardial protection in open heart surgery.

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Blood Biochemical Changes during Periparturient Period in the Holstein Cattle (젖소에서 분만기의 혈액화학치의 변화: 지방간을 중심으로)

  • Lee Kyoung-Kap
    • Journal of Veterinary Clinics
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    • v.10 no.2
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    • pp.163-169
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    • 1993
  • This study examined the incidence of disease and blood biochemical values in 68 Holstein cattle during the a month period after parturition. In order to compare the blood biochemical values, the animals were divided into 2 groups of prepartum and 4 groups of postpartum according to the blood collecting day, respectively. The results compared postpartum with prepartum were obtained as follows : the incidences of displacement of abomasum, culled and retained placenta were 11.8%. 13.2% and 8.8%, respectively. In the normal group(pre and post parturition group), NEFA and bilirubin were increased. Triglyceride and cholesterol were significantly lower than In the pre-parturition group, and total lipid was decreased. In the disease group, displacement of abomasum was significantly higher than in the normal group in the levels of NEFA, triglyceride and bilirubin. Culled was significantly higher than in the normal group in the levels of NEFA, AST and bilirubin. but lower than in the normal group in the levels of triglyceride and cholesterol. Retained placenta was significantly higher than in the normal group in the levels of NEFA and bilirubin, but lower than in the normal group in the levels of triglyceride.

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The Effects of Blood Flow Change to Amplitude Modulated Frequency (진폭변조주파수가 혈류량변화에 미치는 효과)

  • Lee Mun-Hwan;Nam Hyung-Cheon;Park Rae-Joon
    • The Journal of Korean Physical Therapy
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    • v.17 no.2
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    • pp.88-106
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    • 2005
  • AMF(amplitude modulated frequency) is defined as currents in the frequency range 1 to 100Hz. The aim of this study was to determine the effects of blood flow and skin temperature according to different stimulating frequency($1{\sim}30Hz,\;30{\sim}50Hz,\;50{\sim}100Hz$) of interferential currents. The results were as follow; 1. There were statistical significance on the blood flow with IFC 1, IFC 2, and IFC 3 group, and inter-groups(p<0.05). 2. There were statistical significance on the skin temperature with IFC 1 and IFC 3 group, and inter-groups(p<0.05). 3. IFC 1 was more statistical significance than IFC 3 group on blood flow(pP<0.05) 4. There was no statistical significance between IFC 1 and IFC 3 group on skin temperature(p>0.05).

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Preparation of blood-compatible polyurethanes by surface modification (표면개질에 의한 혈액적합성 폴리우레탄의 제조)

  • Han, Dong-Keun;Jeong, Seo-Young;Kim, Young-Ha;Min, Byoung-Goo
    • Proceedings of the KOSOMBE Conference
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    • v.1990 no.11
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    • pp.61-63
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    • 1990
  • To develop better blood compatibility of commercial polyurethane(PU), PU surface was chemically modified wi th a hydrophobic perfluorocarhon or a hydrophilic polyethylene oxide(PEO) and/or sulfonated groups, respectively. The water contact angle of modified PUs varied from $110^{\circ}$ to $0^{\circ}$. All the modified PUs were more blood compatible than untreated PU. In particular, PEO-sulfonate grafted PUs showed a very enhanced antithrombogenicity due to the synergistic effect of PEO and $SO_3$ groups. Therefore more hydrophobic and hydrophilic PU surfaces are promising for improving the blood compatibility.

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Effect of Blood Glucose Levels and Lipid Metabolism on Streptozotocin-induced Diabetic Rats of Processed Sulfur with Cordyceps Militaris Mycelium (동충하초 균사체를 이용한 법제 유황이 STZ 유발 당뇨쥐의 혈당 및 지질대사에 미치는 영향)

  • Kim, Ki-Chul;Kim, Hae-Ja;Cho, Hwa-Eun;Choi, Yun-Hee;Lee, Ki-Nam;Chong, Myong-Soo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.1
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    • pp.144-149
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    • 2009
  • The purpose of this study was evaluated physiological activity of processed sulfur with Cordyceps militaris mycelium. Effect of blood glucose levels and lipid metabolism on streptozotocin-induced Diabetic Rats. To evaluate of hypoglycemic effects in vivo, we examined blood glucose levels, serum lipid profile and hepatotoxicity of streptozotocin (STZ) induced diabetic rats. Hypoglycemic effect of CM, CM+PSL and CM+PSH groups was significantly higher than DC groups. The activities of ALT, AST and ALP in CM+PSH group were lower than DC, PC groups. These results suggested that processed sulfur with Cordyceps militaris mycelium have activities of hypoglycemic effects.

The Effects of Weight Control Program on Body Composition, Blood Pressure, Serum Lipid and Self-Regulation Behavior in Obese College Women (비만중재프로그램이 비만 여대생의 신체구성, 혈압, 혈중지질 및 자기조절행위에 미치는 효과)

  • Kim, Kyung Hae;Chung, Bok Yae;Byun, Hye Sun
    • Korean Journal of Adult Nursing
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    • v.19 no.3
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    • pp.339-352
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    • 2007
  • Purpose: The purpose of this study was to investigate the effect of weight control program on body composition(body mass index and waist-hip ratio), blood pressure, serum lipids(total cholesterol, triglyceride, high density lipoprotein and low density lipoprotein) and self-regulation behavior in obese college women. Methods: Forty seven obese subjects were divided into experimental(22) and control(25) groups. The weight control program lasting 12 weeks consisted of a traffic-light diet, jumping-rope exercises, and behavior modification methods with e-mail counseling. The data were collected from 29 March to 17 September of 2004. The variables were assessed before and after intervention for 12 weeks in two groups. Then, those were repeated after a 12 week suspension of intervention in the experimental group. The data were analysed by the SPSS computer program. Results: BMI, HDL, LDL and self-regulation behavior levels showed significant differences between the experimental and control groups. While there were no significant differences in waist-hip ratio, blood pressure, total cholesterol and triglyceride. Conclusion: The weight control program had a positive effect on obese college women, and can be used to control obesity.

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Effect of Antioxidant vitamin Supplementation on Blood Composition in Smoking College Men (항산화성 비타민 보충 급여가 흡연자의 혈액성상에 미치는 영향)

  • 이성숙
    • Journal of Nutrition and Health
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    • v.31 no.3
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    • pp.289-296
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    • 1998
  • A large body of epidemiologic evidence suggests inverse relationships between ischemic heart disease and plasma vitamin C and E concentrations. Smokers have lower plasma concentrations of these vitamins than do nonsmokers. Smokers therefore need antioxidant vitamin supplementation . The purpose of study was to investigate the effect of antioxidant vitamin supplementation on blood composition in smoking college men. 24 subjects were divided into 3 groups of which were the vitamin C supplementation group(n=8), the vitamin E supplementation group(n=8), and the vitamin C+E supplementation group(n=8). The vitamin supplementation group consumed 500mg of ascorbic acid, the vitamin E supplementation group consumed 200IU of D-$\alpha$-tocopherol , and the vitamin C+E supplementation group consumed 500mg of ascorbic acid +200IU of D-$\alpha$-tocopherol for 4 weeks. We examined the blood compositions of the volunteers bofore and after vitamins were supplemented . The results obtained were as follows ; intakes of energy , carbohydrate , fat protein , vitamin C and vitamin E were not significantly affected by vitamin supplementation in all groups. Blood glucose concentrations were not significantly affected by vitamin supplementation in all groups. Concentrations of plasma uric acid and alkaline phosphatase activity were decreased significantly (p<0.05) with vitamin E supplementation. The results of this study show that antioxidant vitamin supplementation in smokers has a tendency to decrease coronary heart disease risk.

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The Relationship between Patients' Expectations of Treatment Effect and Clinical Outcome in a Trial of Acupuncture for Hypertension (고혈압 침 임상연구에서 환자의 기대치와 치료효과 간의 상관관계)

  • Kim, Junbeom;Liu, Yan;Kim, Jung-Eun;Park, Ji-Eun
    • Journal of Acupuncture Research
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    • v.33 no.4
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    • pp.33-38
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    • 2016
  • Objectives : To identify potential correlation between patients' expectations and clinical outcome in a randomized control study of acupuncture. Methods : In a clinical trial of acupuncture for hypertension, 60 participants with pre and mild hypertension were randomized into an acupuncture group and a control group. After randomization, all participants were asked to rate their expectation for the intervention on a scale of 0 to 10. To analyze the effect of expectation on clinical outcome, change of blood pressure was compared between high and low expectation groups. Results : There was no significant difference of baseline blood pressure between low expectation group and high expectation group. Proportion of acupuncture group and control group was also not different between low and high expectation groups (p = 0.638). The change of systolic blood pressure was -1.55 mmHg in low expectation group and -3.07 mmHg in high expectation group, and it was not significantly different (p = 0.54). There was no significant difference in the change of diastolic blood pressure between two groups (p = 0.58), with -3.24 mmHg in low expectation group and -2.34 mmHg in high expectation group. Conclusion : In this study, the expectation of intervention (including acupuncture treatment) was not associated with the effect of intervention.