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Effect of Blood Glucose Levels and Lipid Metabolism on Streptozotocin-induced Diabetic Rats of Processed Sulfur with Cordyceps Militaris Mycelium  

Kim, Ki-Chul (College of Oriental Medicine, Wonkwang University)
Kim, Hae-Ja (Professional Graduate School of Oriental Medicine, Wonkwang University)
Cho, Hwa-Eun (Professional Graduate School of Oriental Medicine, Wonkwang University)
Choi, Yun-Hee (Professional Graduate School of Oriental Medicine, Wonkwang University)
Lee, Ki-Nam (Professional Graduate School of Oriental Medicine, Wonkwang University)
Chong, Myong-Soo (College of Oriental Medicine, Wonkwang University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.23, no.1, 2009 , pp. 144-149 More about this Journal
Abstract
The purpose of this study was evaluated physiological activity of processed sulfur with Cordyceps militaris mycelium. Effect of blood glucose levels and lipid metabolism on streptozotocin-induced Diabetic Rats. To evaluate of hypoglycemic effects in vivo, we examined blood glucose levels, serum lipid profile and hepatotoxicity of streptozotocin (STZ) induced diabetic rats. Hypoglycemic effect of CM, CM+PSL and CM+PSH groups was significantly higher than DC groups. The activities of ALT, AST and ALP in CM+PSH group were lower than DC, PC groups. These results suggested that processed sulfur with Cordyceps militaris mycelium have activities of hypoglycemic effects.
Keywords
pysiological activity; processed sulfur; cordyceps militaris; blood glucose; hypoglycemic; lipid profile;
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Times Cited By KSCI : 8  (Citation Analysis)
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1 통계청. 사망통계연보. 2006
2 Lim, H.W., Kwon, Y.M., Cho, S.M., Kim, J.H., Yoon, G.H., Lee, S.J., Kim, H.W., Lee, M.W. Antitumor activity of Cordyceps militaris on human cancer cell line. Korean Journal of Pharmacognosy 35(4):364-367, 2004
3 Koh, J.B. The effects of Cordyceps militaris on lipid metabolism, protein levels and enzyme activities in rats fed a high fat diet. The Korean Nutrition Society 35(4):414-420, 2002
4 Koh, J.B., Choi, M.A. Effect of Cordyceps militaris on lipid metabolism in rats fed cholesterol diet. The Korean Nutrition Society 34(3):265-270, 2001
5 본초학교수공저. 본초학 6판. 서울, 영림사, pp 639-640, 1991
6 Kim, D.H., Yang, B.K., Hur, N.J., Das, S., Yun, J.W., Choi, Y.S., Song, C.H. Hypoglycemic of Phellinus linteus (Berk. et curt) Teng (Aphyllophoro mycetideae) in streptozotocin-induced diabetic rats. Int J Med Mushr 3: 21-26, 2001
7 Ditzel, J. Oxygen transport impairment in diabetes. Diabetes 25(Supple 2):832, 1976
8 Campbell, R.K., Steil, C.F. Diabetes, clinical pharmacy and therapeutics, 4th ed. Williams & Wilks, 1988
9 Goldberg, R.B. Lipid disorders in diabetes. Diabetes Care 4: 561-572, 1981   DOI   PUBMED   ScienceOn
10 Lee, S.H., Ko, S.S., Youn, Y.J., Lee, J.I. Effect of Cordyceps militaris on maximal aerobic power and recovery of fatigue. JKSSPE 6(2):187-193, 2002
11 Barretine, B.F., Ruffin, B.G. Salt and gypsum as regulators of cottonseed meal intake. Miss.State Univ. Agri Sta Inform Cheet. p 587, 1958
12 Kim, M.N., Oh, S.W., Lee, D.S., Ham, S.S. Antioxidative and antimutagenic effect of the ethanol extract from Cordyceps militaris. Korean J Postharvest Sci Technol 8(1):109-117, 2001
13 Chae, M.H., No, J.G., Jhon, D.Y. Effect of high fat diet containing Hangbisan on the body weight and blood lipid composition in the rats. J Korean Soc Food Sci Nutr. 35(4):416-421, 2006   DOI   ScienceOn
14 Yang, B.K., Kim, D.H., Song, C.H. Production of Lentinus edodes mycelia in submerged culture and it's hypoglycemic effect in diabetic rats. Kor J Mycol 30: 131-135, 2002   DOI
15 Kim, S.J., Lim, D.K., Park, C.W., Cerbo, R.M., Hyung, S.W., Lee, K.K., Kim, J.O., Ha, Y.L. Inhibition of free radical-induced lipid oxidation by the extract from submerged liquid culture of mushrooms in the medium containing mulberry tree powders. J Korean Soc Food Sci Nutr. 33(2):255-261, 2004   DOI
16 Kim, J.H., Cho, M.R., Ryu, C.R., Chae, W.S. Effect of Cordyceps militaris mycelia (CMM) oral administration and herbal acupuncture at BL13, LU4 on asthma induced by ovalbumin in rats. The Journal of Korean Acupuncture & Moxibution Society 19(2):39-50, 2002
17 Bouchard, R., H.R. Conrad. Sulphur requirement of lactating dairy cows. H. Utilization of sulphates, molasses and lignin-sulfonate. J Dairy Sci 56: 142, 1973
18 Choi, Y.G., Lee, T.H. Diabetes mellitus and hyperlipidemia. Medical Pub, Seoul, pp 111-134, 1995
19 黃魄鞭黈. 神農本草經. 中醫古籍, pp 156-160, 1978
20 Choi, M.S. Influence of body fat distribution on glucose tolerance and serum lipids in patient with non-insulin dependent diabetes mellitus. The Graduate School Yonsei University, 1991
21 김기영, 송호준. 한약포제학. 서울, 신일상사, p 515, 516, 1992
22 Kwon, S.H., Woo, H.J., Han, D.S., Kim, M.K. Effect of dried powders and water extracts of paecilomyces tenuipes and Cordyceps militaris on lipid metabolism, antioxidative capacity and immune status in rats. The Korean Nutrition Society 34(3):271-284, 2001
23 Kim, H.S., Roh, Y.J., Choe, M. Cordyceps militaris increases hepatic glucokinase activities. J Korean Soc Food Sci Nutr 34(2):158-161, 2005   DOI   ScienceOn
24 Gray, A.M.，Flatt, P.R. Insulin-releasing and insulin-like activity of Agaricus campestris (mushroom). J Endocrinol 157: 259-266, 1998   DOI   ScienceOn
25 Yang, B.K., Cho, K.Y., Wilson, M.A., Song, C.H. Effects of Inonotus obliquus mycelia on the level of plasma glucose and lipids in streptozotocin-induced diabetic rats. Kor J Mycol 33: 64-68, 2005   DOI
26 Shon, M.Y., Choi, S.Y., Cho, H.S., Sung, N.J. Effects of cereal and red ginseng flour on blood glucose and lipid level in streptozotocin-induced diabetic rats. J Korean Soc Food Sci Nutr 33(9):1463-1468, 2004   DOI   ScienceOn
27 Rho, H.M., Choi, M.A., Koh, J.B. Effects of raw soy flour (yellow and black) in serum protein concentrations and enzyme activity in streptozotocin-diabetic rats. J Korean Soc Food Sci Nutr 27: 724-730, 1998
28 Narle, A., Krall, L.P., Bradley, R.F., Christlieb, A.R., Soell, J.S. Joslin's, Diabetes mellitus, 12th ed. Philadelphia, Lea & Febiger, 1985
29 Park, C.S., Kwon, C.J., Choi, M.A., Park, G.S., Choi, K.H. Antibacterial activities of Cordyceps spp., Mugwort and pine needle extracts. Korean J of Food Preservation 29: 121-131, 2002