• Title/Summary/Keyword: Bismuth

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Acute Toxicity of DWH-01 (Ranitidine : Bismuth subcitrate : Sucralfate) in Rats (랫트에 있어서 DWH-01(Ranitidine : Bismuth subcitrate : Sucralfate)의 급성독성에 관한 연구)

  • 김형식;박선미;변수현;김용기;이제원;유영효;이향우;이병무
    • Biomolecules & Therapeutics
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    • v.1 no.2
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    • pp.262-265
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    • 1993
  • Acute toxicities of DWH-01 (Ranitidine : Bismuth : Sucralfate= 1.5: 2 : 6) were investigated in Sprague-Dawley rats. Seven days after oral administration of DWH-01 with different doses (10 g/kg, 5 g/kg, 2.5 g/kg, 1.25 g/kg, 0.625 g/kg), we examined numbers of deaths, general signs, weight measurement and histopathological examination for both sexes of rats. Summaried results are: 1) No deaths were occurred, 2) There were no pathological and clinical differences compared with control group, 3) No significant changes of body weights were observed, and 4) In histopathological examinations of organs and tissues, there was some hemorrhage in a lung tissue of low dose group for male and female respectively, but it was thought to be caused by environmental factor. The results suggest that toxicity of DWH-01 is low and its $LD_{50}$ is over 10 g/kg in Sprague-Dawley rats.

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Usefulness of Bismuth Shielding in Cerebral Vascular Intervention (뇌혈관 중재적 시술 시 Bismuth 차폐체 설치의 유용성에 대한 연구)

  • Kim, Jae-seok;Son, Jin-hyun;Kim, Young-kil
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2017.05a
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    • pp.179-182
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    • 2017
  • Cerebral nervous system intervention procedures have been reported frequently due to radiation exposure such as skin baldness, hair loss, and redness due to prolonged procedures. Therefore, the bismuth shield designed to reduce the radiation exposure of the target organ located in the anterior part of the human body sensitive to skin and radiation sensitivity during CT (computed tomography) scan is applied to the cerebral vascular system intervention by ergonomic design, To reduce the radiation dose of sensitive scalp, we propose a study.

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Gamma Ray Shielding Study of Barium-Bismuth-Borosilicate Glasses as Transparent Shielding Materials using MCNP-4C Code, XCOM Program, and Available Experimental Data

  • Bagheri, Reza;Moghaddam, Alireza Khorrami;Yousefnia, Hassan
    • Nuclear Engineering and Technology
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    • v.49 no.1
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    • pp.216-223
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    • 2017
  • In this work, linear and mass attenuation coefficients, effective atomic number and electron density, mean free paths, and half value layer and $10^{th}$ value layer values of barium-bismuth-borosilicate glasses were obtained for 662 keV, 1,173 keV, and 1,332 keV gamma ray energies using MCNP-4C code and XCOM program. Then obtained data were compared with available experimental data. The MCNP-4C code and XCOM program results were in good agreement with the experimental data. Barium-bismuth-borosilicate glasses have good gamma ray shielding properties from the shielding point of view.

Effects of the Nanometer-sized Bismuth Oxide Coating on Shadow Mask

  • Kim, Sang-Mun;Koh, Nam-Je
    • Journal of Information Display
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    • v.6 no.4
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    • pp.40-44
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    • 2005
  • Nanometer-sized bismuth oxide with a diameter of about 80 nm was used as a new electron reflection material in a 29" Real Flat CPT. This bismuth oxide was well dispersed over pH8 in slurry. Spray coating was performed clearly and uniformly and was ensured that there was no clogging of shadow mask hole. Coating thickness was expressed to the brightness of chromaticity for the sprayed layer and was also well controlled during the spraying process. Doming was improved by about 10% in spite of the similar coating weight in comparison with the average 3.5 ${\mu}m$ of the conventional bismuth oxide.

[100]-Texturing of Barium Titanate Ceramics Using Sodium Bismuth Titanate Templates: Challenges and Insights

  • Nu-Ri Ko;Temesgen Tadeyos Zate;Wook Jo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.37 no.3
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    • pp.328-331
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    • 2024
  • This research explores the development of [100]-textured barium titanate (BaTiO3, BT) ceramics using sodium bismuth titanate (Na0.5Bi4.5Ti4O15, NBiT) templates, aimed at leveraging the inherent high dielectric property of BT. However, the attempted texturing was unsuccessful, primarily due to bismuth diffusion from the NBiT templates into the BT matrix below the sintering temperature, at 1,000℃. Systematical exploration about the cause of the failure is involved and alternative approaches are proposed in detail to overcome the challenge. These findings contribute to the understanding of techniques and conditions for textured ceramic fabrication and highlight the need for further research in this area.

Effectiveness of Bismuth Shield to Reduce Eye Lens Radiation Dose Using the Photoluminescence Dosimetry in Computed Tomography (CT 검사에서 유리선량계를 이용한 수정체의 비스무트 차폐 효과)

  • Jung, Mi-Young;Kweon, Dae-Cheol;Kwon, Soo-Il
    • Journal of radiological science and technology
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    • v.32 no.3
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    • pp.307-312
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    • 2009
  • The purpose of our study was to determine the eyeradiation dose when performing routine multi-detector computed tomography (MDCT). We also evaluated dose reduction and the effect on image quality of using a bismuth eye shield when performing head MDCT. Examinations were performed with a 64MDCT scanner. To compare the shielded/unshielded lens dose, the examination was performed with and without bismuth shielding in anthropomorphic phantom. To determine the average lens radiation dose, we imaged an anthropomorphic phantom into which calibrated photoluminescence glass dosimeter (PLD) were placed to measure the dose to lens. The phantom was imaged using the same protocol. Radiation doses to the lens with and without the lensshielding were measured and compared using the Student t test. In the qualitative evaluation of the MDCT scans, all were considered to be of diagnostic quality. We did not see any differences in quality between the shielded and unshielded brain. The mean radiation doses to the eyewith the shield and to those without the shield were 21.54 versus 10.46 mGy, respectively. The lens shield enabled a 51.3% decrease in radiation dose to the lens. Bismuth in-plane shielding for routine eye and head MDCT decreased radiation dose to the lenswithout qualitative changes in image quality. The other radiosensitive superficial organs specifically must be protected with shielding.

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A Study on New Shielding Method for Minimizing Thyroid Oran Dose on Chest Radiography Used Automatic Exposure Control (자동노출조절장치를 이용한 흉부 방사선검사 시 갑상샘 장기선량 최소화를 위한 새로운 차폐 방법에 관한 연구)

  • Joo, Young-Cheol;Hong, Dong-Hee;Han, Beom-Hee
    • Journal of radiological science and technology
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    • v.43 no.5
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    • pp.323-329
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    • 2020
  • The purpose of this study is to investigate the effect of radiation shielding on the thyroid organ dose and image quality during Chest PA examination using automatic exposure control system. This study was conducted in the patient posture and examination conditions such as Chest PA using human model phantom. An experiment without shielding was set as a control group (non) and the cases of using paper coated with a contrast agent (contrast) and bismuth (bismuth) were used as experimental groups. Compared to non-shielded(non), the dose at bismuth increased about 7% in C(cervical vertebrae)5 and C6 and 14% in C7 and contrast showed dose increases of about 17 to 19% in C5 and C6 and about 21% in C7. As a result of the image quality comparison, when measured in the center of the cervical vertebrae, both SNR and CNR in bismuth increased about 40% higher than non, and contrast showed about 8 to 9% improvement. Compared with soft tissues of the cervix, bismuth reduced SNR by about 15% and CNR by about 13%, in contrast, SNR decreased by 11%, and CNR decreased by about 10%. In the Chest PA using AEC, the method of using the shield in front of the collimator has the advantage to observe the anatomical structure of the neck area well compared to the method using the lead. However, the dose at the neck can be increased by 7-21% depending on shielding materials.