• Journal of Electrochemical Science and Technology
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• 제4권4호
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• pp.125-139
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• 2013

The electrical conductive polymers (ECPs) reported at my research group are introduced in this review, which works are started from the late Professor Su-Moon Park's pioneering research for polyaniline at the University of New Mexico. The electrochemical and spectroelectrochemical properties and their applications to sensor and energy conversion systems are briefly described. At first, the growth and degradation mechanism of polyaniline describes and we extend to polypyrrole, polyazulene, polydiaminonaphthalenes, and polyterthiophene derivatives. In addition, the preparation of monomer precursors having functional groups is briefly described that can give us many exceptional applications for several chemical reactions. We describe the application of these ECPs for the fabrication of chemical sensors, biosensors, biofuel cells, and solar cells.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 춘계학술대회
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• pp.1094-1099
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• 2003

Nanometer-sized structures are being applied to many fields including micro/nano electronics, optoelectronics, quantum computing, biosensors, etc. Multi-scale analysis technology is required for designing the reliable nanometer-sized structures and predicting their mechanical, chemical and electronic behaviors. In this paper, some techniques for multi-scale analysis are reviewed and their applicability and limitation are discussed. Research activity of nano process analysis team in KIMM is outlined. Especially, we concentrate on OCTA of Nagoya University in Japan for the analysis of polymeric materials. Detailed structure of OCTA is described and some examples are presented.

• 한국버섯학회지
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• 제15권1호
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• pp.1-7
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• 2017

Hydrophobins are surface active proteins that are produced by filamentous fungi including mushrooms. Their ability to self-assemble into an amphipathic membrane at any hydrophilic-hydrophobic interface is most intriguing. These small secreted proteins comprise of eight conserved cysteine residues which form four disulfide bridges and an extraordinary hydrophobic patch. Hydrophobins play critical roles in fungal (and/or mushrooms) growth as structural components and in the interaction of fungi and mushrooms with the environment. The biophysical and biochemical properties of the isolated proteins are remarkable, such as strong adhesion, high surface activity and the formation of various self-assembled structures. With the increasing demands of hydrophobins from fungi and mushroom sources, production and purification in large scale is under challenge. Various applications, ranging from food industries, cosmetics, nanotechnology, biosensors and electrodes, to biomaterials and pharmaceuticals are emerging and a bright future is foreseen.

• BMB Reports
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• 제44권11호
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• pp.705-712
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• 2011

Advances in the fields of proteomics and genomics have necessitated the development of high-throughput screening methods (HTS) for the systematic transformation of large amounts of biological/chemical data into an organized database of knowledge. Microfluidic systems are ideally suited for high-throughput biochemical experimentation since they offer high analytical throughput, consume minute quantities of expensive biological reagents, exhibit superior sensitivity and functionality compared to traditional micro-array techniques and can be integrated within complex experimental work flows. A range of basic biochemical and molecular biological operations have been transferred to chip-based microfluidic formats over the last decade, including gene sequencing, emulsion PCR, immunoassays, electrophoresis, cell-based assays, expression cloning and macromolecule blotting. In this review, we highlight some of the recent advances in the application of microfluidics to biochemistry and molecular biology.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 추계학술대회
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• pp.1927-1931
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• 2003

Nanometer-sized structures are being applied to many fields including micro/nano electronics, optoelectronics, quantum computing, biosensors, etc. Micro contact printing is one of the most promising methods for manufacturing the nanometer-sized structures. The crucial element for the micro contact printing is the nano-resolution printing technique using polymeric stamps. In this study, a multi-scale analysis scheme for simulating the micro contact printing process is proposed and some useful analysis results are presented. Using the slip-link model [1], the dependency of viscoelasticity on molecular weight of polymer stamp is predicted. Deformation behaviors of polymeric stamps are analyzed using finite element method based upon the predicted viscoelastic properties.

• 한국산학기술학회논문지
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• 제6권1호
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• pp.24-28
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• 2005

3차원 실리콘 챔버를 갖는 $15.8{\times}15.8 mm^2$크기의 칩을 바이오 센서용으로 마이크로머시닝 기술을 이용하여 개발하였다. 비등방성 식각기술을 이용하여 (100)방향의 p형 실리콘 웨이퍼위에 마이크로 챔버를 형성하였다. 마이크로 챔버를 갖는 웨이퍼와 백금전극이 도포된 Pyrex 유리를 DGF-48S 접착제를 이용하여 접합하였다. 백금전극과 Ag/AgCl 기준전극에 의한 전기화학적 특성을 조사하였다.

• Journal of Microbiology and Biotechnology
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• 제14권4호
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• pp.783-788
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• 2004

Marker proteins of genetically-modified organisms (GMO) and their antibodies were prepared and characterized as major components of an analytical system. We selected two GMO markers, neomycin phosphotransferase II and 5- enolpyruvylshikimate-3-phosphate synthase, and produced them from E. coli employing genetic recombination technology. After purification, their structural conformation and binding affinities to the respective antibodies were characterized. The results showed that the recombinant proteins were identical with commercially obtained reference proteins. We further used them as immunogens to raise polyclonal antibodies capable of discriminating GMO containing protein from non-GMO. Well-characterized marker proteins and antibodies will be valuable as immunoreagents in constructing analytical systems such as biosensors and biochips to measure quantities of GMO.

• 센서학회지
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• 제18권2호
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• pp.168-172
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• 2009

In this paper, we present the carbon nanotube field-effect transistor(CNT-FET) with a double-gate structure. A Carbon nanotube film was aligned by the Langmuir-Blodgett technique and $SiN_x$ was deposited to protect from water, oxygen, and other contaminants. We measured the electrical characteristics of the proposed device as the function of the $V_{BG}$, $V_{TG}$. From this result, we can confirm that proposed device might be employed as a biosensor.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2011년도 제40회 동계학술대회 초록집
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• pp.7-7
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• 2011

Graphene and graphene derivatives have attracted enormous attention from various research fields for applications in electronic devices, transparent electrodes, biosensors, drug delivery system and surface coatings. In the viewpoint of chemist, the chemical structure of graphene derivatives seems intriguing but detailed structures are being revealed only recently while engineering approaches for various applications are being executed very actively. In addition, cytotoxicity and mammalian cellular responses to graphene have not thoroughly investigated yet in spite of the importance in bio-applications and environment. In this talk, I'll introduce recent studies which report cytotoxicity and behaviors of mammalian cells when the cells are exposed to graphene (as well as some bio-applications of graphene), especially to get closer to answers to these questions, "how we understand and how/why we use graphene in biotechnology".

• 센서학회지
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• 제27권1호
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• pp.25-30
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• 2018

Closed-form analytical expressions and 3-dimensional normalized charts for the homogeneous sensing and surface sensing structures are derived to provide the conditions for the maximum sensitivity of integrated-optic biosensors based on evanescent-wave and stepindex planar optical waveguides. The analysis is made for transverse electric (TE) polarization mode, in both cases where the measurand is homogeneously distributed in the cover (namely, homogeneous sensing), and where it is an ultrathin film on the waveguide-cover interface (namely, surface sensing).