• Archives of Pharmacal Research
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• v.8 no.3
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• pp.109-117
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• 1985

The interaction of salicylic acid (S. A.), salicylamide (S,M) with nucleic acid base derivatives such as 9-ethyl adenine (A), 1-cyclohexyl uracil (U), 2', 3'-benzylidine-5' trityl-cytidine (C), gaunosine-2', 3', 5'-isobutylate (G) has been spectroscopically investigated to determine the binding mechanism. NMR and IR spectra were measured in nonpolar solvents. The association constant K of the formation of complex was calculated from the IR spectra. Compounds S. A. and A form a 1:1 or 1:2 cyclic hydrogen-bonded complex depending on the sample concentration. Compounds S. A. and U form a 1:1 or 1:2 hydrogen-bonded complex on the sample concentration. Compounds S. A. and C form a 2:1 hydrogen-bonded complex at low concentration (0.0016M). Compound S. A. binds compound G, but its binding does not completely break the self-association of compound G, Compound S. M. binds compounds A. U. C. G. very weakly.

• Journal of The Korean Society of Agricultural Engineers
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• v.54 no.2
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• pp.77-86
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• 2012

This study was aim to predict future land-cover changes and to analyze regional land-cover changes in irrigation areas and agricultural reservoir watersheds under climate change scenario. To simulate the future land-cover under climate change scenario - A1B of the SRES (Special Report on Emissions Scenarios), Dyna-CLUE (Conversion of Land Use Change and its Effects) was applied for modeling of competition among land-use types in relation to socioeconomic and biophysical driving factors. For the study areas, 8 agricultural reservoirs were selected from 8 different provinces covering all around nation. The simulation results from 2010 to 2100 suggested future land-cover changes under the scenario conditions. For Madun reservoir in Gyeonggi-do, total decrease amount of paddy area was a similar amount of 'Base demand scenario' of Water Vision 2020 published by MLTMA (Ministry of Land, Transport and Maritime Affairs), while the decrease amounts of paddy areas in other sites were less than the amount of 'High demand scenario' of Water Vision 2020. Under A1B scenario, all the land-cover results showed only slight changes in irrigation areas of agricultural reservoirs and most of agricultural reservoir watersheds will be increased continuously for forest areas. This approach could be useful for evaluating and simulating agricultural water demand in relation to land-use changes.

• Journal of fish pathology
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• v.7 no.2
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• pp.105-112
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• 1994

A new bacterial infection occurred among the cultured Korean catfish, Silurus asotus, in Chunbuk prefecture, Korea, 1993. This disease produced about 30% mortality in the fish for 4 months. The diseased fish was swimming listless at the water surface with head up and tail down, sometimes spinnig in circles. The most outstanding clinical sign was ulceration on the skull and at the base of the pectoral fins. The causative organism was isolated from the brain, kidney, spleen and liver of diseased fish, and identified as Edwardsiella icaluri by the biochemical and biophysical characteristics. After intraperitoneal innoculaton of the isolate, the pathogenicity was proved positive for Korean catfish, S. asotus, and channel catfish, Ictalurus punctatus, but negative for carp, Cyprinus carpio.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.2 no.1
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• pp.55-66
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• 1995

The goals of nursing education, and the bases for evaluating them depend on the goals of nursing practice. In order to prepare for the coming twenty first century and the meet changing societal demands and health needs, it is necessary to develop a new conceptual framework for future nursing education. While hospitals will still be in significant components of the health care system, will no longer be central focus or dominant influence. Health care services will be more usually delivered at community base. The nursing education required by that new approach must provide for reconsidered about a concept of caring as nursing curriculum. The changes in health care delivery that have occured, now being proposed, for nursing education undergoing its own changes. So the philosophy and objectives of education meed to reconsidering about the caring concept and general nursing. Nurse educators must prepare students to practic in condition of constant change. At the same time nurse educators must emphasize preparation about that. The practice of science of caring in nursing draws on a basic knowledge of the behavioral knowledge, biophysical processes, pathological processes, nursing skills and procedures and various treatment regimes and problem solving to help decision making in nursing situations. The concept of care is probably one of the least understood ideas used by professional and nonprofessional people, yet it is probably one of the most improtant concepts to be understood by nursing. Human caring and human relationships are closely interrelated. Humn caring remains an essential dimension of professional work and the science of caring as essental to the discipline of nursing. It is expected that the objectives of nursing education will be accomplished when the course and content of the curriculum are based on this conceptual framework. One recurrent education goal with some consistency is that of equipping the student with the necessary skills to live effectively and productivly in the world of tomorrow. In the new vision we are developing, professional education must also include exposure to liberal arts, encouragement of critical thinking, and a moral context for advanced professional education that is based upon a contextual health policy and caring science educational model.

• Journal of the Korean Chemical Society
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• v.54 no.5
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• pp.573-578
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• 2010

In this study, iron(III)-2,4-dihydroxysalophen chloride (Fe(2,4-DHSalophen)Cl), has been synthesized by combination of 2,4-dihydroxysalophen (2,4-DHSalophen) with $FeCl_2$ in a solvent system. This complex combination was characterized using UV-vis and IR spectroscopies. Subsequently, the interaction between native calf thymus deoxyribonucleic acid (ct-DNA) and Fe(2,4-DHSalophen)Cl, was investigated in 10 mM Tris/HCl buffer solution, pH 7.2, using UV-visible absorption and fluorescence spectroscopies, thermal denaturation technique and viscosity measurements. From spectrophotometric titration experiments, the binding constant of Fe(2,4-DHSalophen)Cl with ct-DNA was found to be $(1.6{\pm}0.2){\times}10^3\;M^{-1}$. The fluorescence study represents the quenching effect of Fe(2,4-DHSalophen)Cl on bound ethidium bromide to DNA. The quenching process obeys linear Stern-Volmer equation in extended range of Fe(2,4-DHSalophen)Cl concentration. Thermal denaturation experiments represent the increasing melting temperature of DNA (about $4.3^{\circ}C$) due to binding of Fe(2,4-DHSalophen)Cl. These results are consistent with a binding mode dominated by interactions with the groove of ct-DNA.

• Korean journal of applied entomology
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• v.42 no.1
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• pp.43-51
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• 2003

This study was carried out to develop the forecasting model of Pseudococcus comtocki Kuwana for timing spray. Field phonology and temperature-dependent development of p. comstocki were studied, and its stage transition models were developed. p comstocki occurred three generations a year in Suwon. The 1 st adults occurred during mid to late June, and the 2nd adults were abundant during mid to late August. The 3rd adults were observed after late October. The development times of each instar of p. comstocki decreased with increasing temperature up to 25$^{\circ}C$, and thereafter the development times increased. The estimated low-threshold temperatures were 14.5, 8.4, 10.2, 11.8, and 10.1$^{\circ}C$ for eggs, 1st+2nd nymphs, 3rd nymphs, preoviposition, and 1st nymphs to preoviposition, respectively. The degree-days (thermal constants) for completion of each instar development were 105 DD for egg,315 DD for 1st+2nd nymph, 143 DD for 3rd nymph, 143 DD for preoviposition, and 599 DD for 1 st nymph to preoviposition. The stage transition models of p. comstocki, which simulate the proportion of individuals shifted from a stage to the next stage, were constructed using the modified Sharpe and DeMichele model and the Weibull function. In field validation, degree-day models using mean-minus-base, sine wave, and rectangle method showed 2-3d, 1-7d, and 0-6 d deviation with actual data in predicting the peak oviposition time of the 1st and 2nd generation adults, respectively. The rate summation model, in which daily development rates estimated by biophysical model of Sharpe and DeMichele were accumulated, showed 1-2 d deviation with actual data at the same phonology predictions.