• Journal of Electrical Engineering and Technology
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• 제10권5호
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• pp.2155-2161
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• 2015

This study suggests an optical method to measure cardinal of gait (step width, step length, and stride length) with position sensitive detector (PSD). The effect of reflector’s shape (flat and cylinder) on the PSD output voltage was examined for the application of the suggested system to real situations with a curved shape reflector (e.g. shoes). Various mathematical models were evaluated to find the optimal equation for the distance measurement. Considering the effect of shape on detected signal, the inverse polynomial model was developed. The suggested method is simple to operate, low in cost, small in size, and can evaluate gait parameters in real time. This method is expected to be useful in the field of rehabilitation and sport science

• 전기학회논문지
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• 제64권4호
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• pp.605-611
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• 2015

The measurement and analysis of angular change have been studied in many fields. This study developed an angle measurement technique with optical fiber and photodiode. The position and attached angle of photodiode were investigated to find the proper combination of parameter. The results showed that the increased measuring range was achieved when the position of detector was away from the center of rotation. Inverse mathematical model was used to obtain angular changes with an optical fiber. The applications of this study include in optical sensor, joint angle measurement, and sport science.

• 센서학회지
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• 제20권2호
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• pp.96-101
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• 2011

In this study, we fabricated a fiber-optic phantom dosimeter by arraying square type of plastic optical fibers in a PMMA phantom for measuring relative depth doses of therapeutic photon beams. To minimize the cross-talk between fiber-optic dosimeters, we selected appropriate septum by measuring leaked scintillating lights according to the various kinds of septa. In addition, we measured percentage depth doses of 6, 15 MV photon beams using a fiber-optic phantom dosimeter.

• Journal of the Optical Society of Korea
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• 제20권1호
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• pp.22-28
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• 2016

The monitoring and measurement of the motion of a human joint is very important in screening for degenerative brain diseases and tracking the rehabilitation process. Since there are various medical fields to benefit from angular motion measurement, the necessity for monitoring of human joint movement is increasing. In this study, the optical sensor is composed of a light emission unit with a red LED and an optical fiber, and a reception unit with an arrangement of three photodiodes. The angular detection range was widened with the use of multiple photodiodes and the developed algorithm. The result will be useful for designing an effective angular sensor with low cost and small size.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2015년도 제46회 하계학술대회
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• pp.1407-1408
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• 2015

현재에는 과거와 달리 표면상 비춰지는 외모의 중요성이 강조되어 치아 교정을 해서 미적 욕구를 충족시키려는 사람들이 증가하고 있다. 특히나 치아를 교정할 때 사용되는 치아교정용 브라켓은 부착되는 위치가 치아 앞면이기 때문에 미관상의 중요성은 치아교정장치 중 가장 크다. 이러한 이유 때문에 미적인 부분을 고려하여 치아색과 유사한 브라켓이 개발되었는데, 이 브라켓은 레진 브라켓이다. 이는 치아 교정에 도움을 주면서 심미성이 우수한 장점이 있지만 음식을 섭취할 때 음식의 색소에 의해 브라켓의 색 변화가 일어난다는 단점이 있다. 본 연구에서는 사람들이 자주 섭취하는 음식이나 음료에 치아교정용 브라켓을 착색시켜 색이 변하는 정도의 차이를 컬러센서를 이용해 측정하였다. 이렇게 측정된 브라켓의 RGB 값은 객관적이고 정량적인 값을 나타낼 수 있다. 이는 브라켓의 변색 뿐만 아니라 치아 미백 치료에도 적용되어 사용될 수 있을 것이다.

• BMB Reports
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• 제55권7호
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• pp.323-335
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• 2022

Together with neuronal loss, the existence of insoluble inclusions of alpha-synuclein (α-syn) in the brain is widely accepted as a hallmark of synucleinopathies including Parkinson's disease (PD), multiple system atrophy, and dementia with Lewy body. Because the α-syn aggregates are deeply involved in the pathogenesis, there have been many attempts to demonstrate the mechanism of the aggregation and its potential causative factors including post-translational modifications (PTMs). Although no concrete conclusions have been made based on the previous study results, growing evidence suggests that modifications such as phosphorylation and ubiquitination can alter α-syn characteristics to have certain effects on the aggregation process in PD; either facilitating or inhibiting fibrillization. In the present work, we reviewed studies showing the significant impacts of PTMs on α-syn aggregation. Furthermore, the PTMs modulating α-syn aggregation-induced cell death have been discussed.

• 대한의생명과학회지
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• 제22권4호
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• pp.127-139
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• 2016

A species of the fungal genus Cordyceps has been used as an ingredient of traditional Chinese medicine. In this study, we prepared cordycepin-enriched WIB-801CE, an ethanol extract from culture solution of Cordyceps militaris-hypha, and evaluated its antiplatelet effects on human platelet aggregation. WIB-801CE dose-dependently inhibited ADP-, collagen-, and thrombin-induced platelet aggregation. These antiplatelet effects by WIB-801CE were associated with the attenuation of thromboxane $A_2$ ($TXA_2$) production and serotonin release by ADP, collagen, and thrombin. The inhibition of $TXA_2$ production by WIB-801CE was due to the inhibition of cyclooxygenase-1, $TXA_2$ synthase, and cytosolic phospholipase $A_2$ activity. Therefore, these data suggest that WIB-801CE may be a beneficial component against protection from platelet aggregation-mediated thrombotic disease.

• 대한의생명과학회지
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• 제10권1호
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• pp.9-13
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• 2004

We have investigated the effects of hypha-water extracts (HWE), fruit body-water extracts (FWE) and cordycepin from Cordyceps militaris on serotonin release out of human platelets and human platelet aggregation. HWE and FWE inhibited the release of [$^3H$]-serotonin from human platelet stimulated by thrombin (2 U/ml) or collagen (20$\mu$g/ml) in a dose-dependent manner. Furthermore, cordycepin, a major component of Cordyceps militaris, inhibited the human platelet aggregation induced by collagen (10$\mu$g/ml) in a dose-dependent manner. These results suggest that cordycepin containing in HWE and FWE may inhibit the serotonin release by suppressing the collagen-induced human platelet aggregation. Accordingly, our data demonstrate that HWE and FWE containing much cordycepin might have antithrombotic and antimigrainous functions.

• 전기학회논문지
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• 제64권5호
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• pp.792-798
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• 2015

Joint angle generally can be measured to check the recovery process in rehabilitation field. This paper suggests to measure joint angle with Infrared sensor based on triangulation principle. We performed various experiments to find the optimal condition of the sensor’s attached distance, height, and angle. The results were compared with commercial goniometer for accuracy. The proposed infrared joint angle sensor can be effectively used in rehabilitation and sport science fields.

• 전기학회논문지
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• 제64권1호
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• pp.159-164
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• 2015

Color is distinguished due to the light in which natural light is reflected by object and made with combination of RGB(red, green, blue; three colors). This study proposes color analysis system with optical method to be used conveniently. Color information of sample is determined with the optical sensor. By using the CIE diagram in particular, it detects purity value and wavelength. The method to distinguish color is very economical, simple, and convenient. The result can be used to confirm accurate information of color for various applications.