• 제목/요약/키워드: Biomedical machine learning

검색결과 80건 처리시간 0.02초

Machine Learning-based Prediction of Relative Regional Air Volume Change from Healthy Human Lung CTs

  • Eunchan Kim;YongHyun Lee;Jiwoong Choi;Byungjoon Yoo;Kum Ju Chae;Chang Hyun Lee
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제17권2호
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    • pp.576-590
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    • 2023
  • Machine learning is widely used in various academic fields, and recently it has been actively applied in the medical research. In the medical field, machine learning is used in a variety of ways, such as speeding up diagnosis, discovering new biomarkers, or discovering latent traits of a disease. In the respiratory field, a relative regional air volume change (RRAVC) map based on quantitative inspiratory and expiratory computed tomography (CT) imaging can be used as a useful functional imaging biomarker for characterizing regional ventilation. In this study, we seek to predict RRAVC using various regular machine learning models such as extreme gradient boosting (XGBoost), light gradient boosting machine (LightGBM), and multi-layer perceptron (MLP). We experimentally show that MLP performs best, followed by XGBoost. We also propose several relative coordinate systems to minimize intersubjective variability. We confirm a significant experimental performance improvement when we apply a subject's relative proportion coordinates over conventional absolute coordinates.

PubMiner: Machine Learning-based Text Mining for Biomedical Information Analysis

  • Eom, Jae-Hong;Zhang, Byoung-Tak
    • Genomics & Informatics
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    • 제2권2호
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    • pp.99-106
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    • 2004
  • In this paper we introduce PubMiner, an intelligent machine learning based text mining system for mining biological information from the literature. PubMiner employs natural language processing techniques and machine learning based data mining techniques for mining useful biological information such as protein­protein interaction from the massive literature. The system recognizes biological terms such as gene, protein, and enzymes and extracts their interactions described in the document through natural language processing. The extracted interactions are further analyzed with a set of features of each entity that were collected from the related public databases to infer more interactions from the original interactions. An inferred interaction from the interaction analysis and native interaction are provided to the user with the link of literature sources. The performance of entity and interaction extraction was tested with selected MEDLINE abstracts. The evaluation of inference proceeded using the protein interaction data of S. cerevisiae (bakers yeast) from MIPS and SGD.

기계 학습을 이용한 바이오 분야 학술 문헌에서의 관계 추출에 대한 실험적 연구 (An Experimental Study on the Relation Extraction from Biomedical Abstracts using Machine Learning)

  • 최성필
    • 한국문헌정보학회지
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    • 제50권2호
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    • pp.309-336
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    • 2016
  • 본 논문에서는 지지벡터기계(Support Vector Machines, SVM) 기반의 기계 학습 모듈을 활용하여 특정 문장 내에서의 두 개체 간의 관계를 자동으로 식별하고 분류하는 바이오 분야 관계 추출 시스템을 제안한다. 제안된 시스템의 특징은 개체를 포함하고 있는 문장 내에서 풍부한 언어 자질을 추출하여 학습에 활용함으로써 그 성능을 극대화할 수 있는 다양한 기능들을 포함하고 있다는 점이다. 제안된 시스템의 성능 측정을 위해서 전 세계적으로 많이 활용되고 있는 바이오 분야 관계 추출 표준 컬렉션 3가지를 활용하여 심층적인 실험을 수행한 결과 모든 컬렉션에서 높은 성능을 획득하여 그 우수성을 입증하였다. 결론적으로, 본 논문에서 수행한 바이오 분야 관계 추출에 대한 광범위하고 심층적인 실험 연구가 향후 기계학습 기반의 바이오 분야 텍스트 분석 연구에 많은 시사점을 제공할 것으로 보인다.

자연어 처리 기반 『상한론(傷寒論)』 변병진단체계(辨病診斷體系) 분류를 위한 기계학습 모델 선정 (Selecting Machine Learning Model Based on Natural Language Processing for Shanghanlun Diagnostic System Classification)

  • 김영남
    • 대한상한금궤의학회지
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    • 제14권1호
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    • pp.41-50
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    • 2022
  • Objective : The purpose of this study is to explore the most suitable machine learning model algorithm for Shanghanlun diagnostic system classification using natural language processing (NLP). Methods : A total of 201 data items were collected from 『Shanghanlun』 and 『Clinical Shanghanlun』, 'Taeyangbyeong-gyeolhyung' and 'Eumyangyeokchahunobokbyeong' were excluded to prevent oversampling or undersampling. Data were pretreated using a twitter Korean tokenizer and trained by logistic regression, ridge regression, lasso regression, naive bayes classifier, decision tree, and random forest algorithms. The accuracy of the models were compared. Results : As a result of machine learning, ridge regression and naive Bayes classifier showed an accuracy of 0.843, logistic regression and random forest showed an accuracy of 0.804, and decision tree showed an accuracy of 0.745, while lasso regression showed an accuracy of 0.608. Conclusions : Ridge regression and naive Bayes classifier are suitable NLP machine learning models for the Shanghanlun diagnostic system classification.

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기계학습 기반 췌장 종양 분류에서 프랙탈 특징의 유효성 평가 (Evaluation of the Effect of using Fractal Feature on Machine learning based Pancreatic Tumor Classification)

  • 오석;김영재;김광기
    • 한국멀티미디어학회논문지
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    • 제24권12호
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    • pp.1614-1623
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    • 2021
  • In this paper, the purpose is evaluation of the effect of using fractal feature in machine learning based pancreatic tumor classification. We used the data that Pancreas CT series 469 case including 1995 slice of benign and 1772 slice of malignant. Feature selection is implemented from 109 feature to 7 feature by Lasso regularization. In Fractal feature, fractal dimension is obtained by box-counting method, and hurst coefficient is calculated range data of pixel value in ROI. As a result, there were significant differences in both benign and malignancies tumor. Additionally, we compared the classification performance between model without fractal feature and model with fractal feature by using support vector machine. The train model with fractal feature showed statistically significant performance in comparison with train model without fractal feature.

특징점 선택방법과 SVM 학습법을 이용한 당뇨병 데이터에서의 당뇨병성 신장합병증의 예측 (Prediction of Diabetic Nephropathy from Diabetes Dataset Using Feature Selection Methods and SVM Learning)

  • 조백환;이종실;지영준;김광원;김인영;김선일
    • 대한의용생체공학회:의공학회지
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    • 제28권3호
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    • pp.355-362
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    • 2007
  • Diabetes mellitus can cause devastating complications, which often result in disability and death, and diabetic nephropathy is a leading cause of death in people with diabetes. In this study, we tried to predict the onset of diabetic nephropathy from an irregular and unbalanced diabetic dataset. We collected clinical data from 292 patients with type 2 diabetes and performed preprocessing to extract 184 features to resolve the irregularity of the dataset. We compared several feature selection methods, such as ReliefF and sensitivity analysis, to remove redundant features and improve the classification performance. We also compared learning methods with support vector machine, such as equal cost learning and cost-sensitive learning to tackle the unbalanced problem in the dataset. The best classifier with the 39 selected features gave 0.969 of the area under the curve by receiver operation characteristics analysis, which represents that our method can predict diabetic nephropathy with high generalization performance from an irregular and unbalanced dataset, and physicians can benefit from it for predicting diabetic nephropathy.

어류의 외부형질 측정 자동화 개발 현황 (Current Status of Automatic Fish Measurement)

  • 이명기
    • 한국수산과학회지
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    • 제55권5호
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    • pp.638-644
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    • 2022
  • The measurement of morphological features is essential in aquaculture, fish industry and the management of fishery resources. The measurement of fish requires a large investment of manpower and time. To save time and labor for fish measurement, automated and reliable measurement methods have been developed. Automation was achieved by applying computer vision and machine learning techniques. Recently, machine learning methods based on deep learning have been used for most automatic fish measurement studies. Here, we review the current status of automatic fish measurement with traditional computer vision methods and deep learning-based methods.

A Study on Jaundice Computer-aided Diagnosis Algorithm using Scleral Color based Machine Learning

  • Jeong, Jin-Gyo;Lee, Myung-Suk
    • 한국컴퓨터정보학회논문지
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    • 제23권12호
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    • pp.131-136
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    • 2018
  • This paper proposes a computer-aided diagnostic algorithm in a non-invasive way. Currently, clinical diagnosis of jaundice is performed through blood sampling. Unlike the old methods, the non-invasive method will enable parents to measure newborns' jaundice by only using their mobile phones. The proposed algorithm enables high accuracy and quick diagnosis through machine learning. In here, we used the SVM model of machine learning that learned the feature extracted through image preprocessing and we used the international jaundice research data as the test data set. As a result of applying our developed algorithm, it took about 5 seconds to diagnose jaundice and it showed a 93.4% prediction accuracy. The software is real-time diagnosed and it minimizes the infant's pain by non-invasive method and parents can easily and temporarily diagnose newborns' jaundice. In the future, we aim to use the jaundice photograph of the newborn babies' data as our test data set for more accurate results.

반향 소리를 이용한 기계 학습 기반 수박의 당도 예측 (Prediction of watermelon sweetness using a reflected sound)

  • 김기훈;우지환
    • 한국융합학회논문지
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    • 제11권8호
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    • pp.1-6
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    • 2020
  • 수박의 맛을 평가하는 다양한 방식이 있으나, 기존의 방법들은 주관적 방식, 평가 비용, 대상의 손상 등과 같은 평가 방식의 한계점이 있다. 최근에는 이러한 단점들을 해소하기 위해 소리를 이용하여 수박을 평가하는 연구들이 진행되고 있다. 본 연구에서는 수박을 두드렸을 때 나는 반향 소리를 AI기반의 기계 학습을 이용하여 수박의 당도를 예측하는 모델을 개발 하였다. 수박의 당도가 높을수록 높은 주파수 성분이 특이점으로 나타나며, 따라서 반향소리 시간-주파수 특이점에 기반 하여 기계 학습 방법을 개발하였다. 2개의 수박 당도별 그룹을 구분 시에 83.2%, 3개의 그룹을 구분시에 59.6%의 정확도로 당도를 예측 할 수 있었다.

BCI(Brain-Computer Interface)에 적용 가능한 상호작용함수 기반 자율적 기계학습 (Unsupervised Machine Learning based on Neighborhood Interaction Function for BCI(Brain-Computer Interface))

  • 김귀정;한정수
    • 디지털융복합연구
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    • 제13권8호
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    • pp.289-294
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    • 2015
  • 본 연구는 비교사학습의 대표적인 방법 중 하나인 코호넨의 자기조직화 방법을 기반으로 BCI(Brain-Computer Interface)에 적용 가능한 자율적 기계학습방법을 제안한다. 이를 위해 상호작용 함수를 이용한 학습영역조정방법과 자율적 기계학습규칙을 제안하였다. 학습영역조정과 기계학습은 코호넨의 자기조직화 방법을 기반으로 한 상호작용 함수에 의한 측면제어효과를 이용하였다. 승자 뉴런을 결정하고 난 후 학습 규칙에 따라 뉴런의 연결강도를 조정하고 학습 횟수가 증가함에 따라 학습영역이 점차 감소하여 출력층 뉴런 가중치들의 입력을 향한 유동을 완화시켜 네트워크가 평형 상태(equilibrium state)에 도달하여 학습을 마칠 수 있는 자율적 기계학습을 제안하였다.