• Title/Summary/Keyword: Biomedical field

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Evaluation of Coding Performance and Design of Spatial Multiplexer or 3D Endoscopic Image Processing (3D 내시경 영상처리를 위한 다중화기 설계와 부호화 성능평가)

  • Song, C.G.;Lee, S.M.;Lee, Y.M.;Kim, W.K.;Hwang, J.D.;Kim, J.H.;Lee, M.H.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.11
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    • pp.137-141
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    • 1997
  • In this study, in order to improve visualization and enhance the ability of the surgeon to perform delicate endoscopic surgery, three dimensional endoscopic system is designed. These 3D systems have our features of stereoendoscopic image processing: real time image capture and retrieve; presentation of left and right image on a single monitor; separable processing of the left and right eye images; coding of the 3D endoscopic video. For 3D endoscopic video coding, three approaches are presented based on interlaced picture structure, side-field format structure, and simulcast technique. Experimental results and performances comparisons are presented and analyzed or these approaches. Digital video coding techniques are presented or 3D endoscopic video sequences by means of an MPEG-2 video coding.

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Magnetic Properties of Two-layered Ferromagnetic Films with a Conetic Intermediately Super-soft Magnetic Layer of Different Thickness

  • Choi, Jong-Gu;Sim, Jung-Taek;Kwak, Tae-Jun;Son, Il-Ho;Hwang, Do-Guwn;Rhee, Jang-Rho;Lee, Sang-Suk
    • Proceedings of the Korean Magnestics Society Conference
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    • 2010.06a
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    • pp.148-150
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    • 2010
  • Two-layered ferromagnetic alloy films ($Ni_{80}Fe_{20}$, $Co_{90}Fe_{10}$) with a Conetic intermediate soft magnetic layer of different thickness were investigated to correlate the coercivity values and magnetization process with the strength of the hard saturation field. The interpretation of strong, medium and weak coupling is proposed.

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A Case Study on the Application of Gender Analysis Methods to Biomedical Engineering Capstone Design (의공학 캡스톤디자인 수업에서의 젠더분석 방법 적용사례)

  • Lee, JiYeoun
    • Journal of Engineering Education Research
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    • v.23 no.1
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    • pp.59-64
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    • 2020
  • The purpose of this study is to develop capstone design model of gender analysis methods suitable for engineering education field and examine improvements and effects by applying it to actual lessons for biomedical engineering students. Case study was performed to achieve the purpose of the study. Twelve gender analysis methods were applied to 'biomedical engineering capstone design' which was major course offered by department of biomedical engineering at J university. After the students understood how to analyze gender analysis methods and cases, they decided project topics and presented what gender analysis methods were applied for each project. Additionally, the results of analysis showed that the students were more able to understand the differences between men and women of all ages and try to narrow down the differences. They also found that they could contribute to development of new added value of knowledge and technology that reflected the needs of both men and women by applying gender analysis methods in system development.

GraPT: Genomic InteRpreter about Predictive Toxicology

  • Woo Jung-Hoon;Park Yu-Rang;Jung Yong;Kim Ji-Hun;Kim Ju-Han
    • Genomics & Informatics
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    • v.4 no.3
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    • pp.129-132
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    • 2006
  • Toxicogenomics has recently emerged in the field of toxicology and the DNA microarray technique has become common strategy for predictive toxicology which studies molecular mechanism caused by exposure of chemical or environmental stress. Although microarray experiment offers extensive genomic information to the researchers, yet high dimensional characteristic of the data often makes it hard to extract meaningful result. Therefore we developed toxicant enrichment analysis similar to the common enrichment approach. We also developed web-based system graPT to enable considerable prediction of toxic endpoints of experimental chemical.

Bioinformatics and Genomic Medicine (생명정보학과 유전체의학)

  • Kim, Ju-Han
    • Journal of Preventive Medicine and Public Health
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    • v.35 no.2
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    • pp.83-91
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    • 2002
  • Bioinformatics is a rapidly emerging field of biomedical research. A flood of large-scale genomic and postgenomic data means that many of the challenges in biomedical research are now challenges in computational sciences. Clinical informatics has long developed methodologies to improve biomedical research and clinical care by integrating experimental and clinical information systems. The informatics revolutions both in bioinformatics and clinical informatics will eventually change the current practice of medicine, including diagnostics, therapeutics, and prognostics. Postgenome informatics, powered by high throughput technologies and genomic-scale databases, is likely to transform our biomedical understanding forever much the same way that biochemistry did a generation ago. The paper describes how these technologies will impact biomedical research and clinical care, emphasizing recent advances in biochip-based functional genomics and proteomics. Basic data preprocessing with normalization, primary pattern analysis, and machine learning algorithms will be presented. Use of integrated biochip informatics technologies, text mining of factual and literature databases, and integrated management of biomolecular databases will be discussed. Each step will be given with real examples in the context of clinical relevance. Issues of linking molecular genotype and clinical phenotype information will be discussed.

A Study of the Micor Mechanical System by Using the Magnetic Fluid (자성유체를 개입한 Micro Mechanical System에 관한 연구)

  • Kim, Dong-Wook;Kim, Nam-Gyun;Kim, Bu-Gil;Yuhta, Toshio
    • Journal of Biomedical Engineering Research
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    • v.14 no.2
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    • pp.147-153
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    • 1993
  • In this paper, we studied about the micro pressure transmission system using fluid. For the investigation of feasibility of microhydraulic system, the hydraulic characteristics were examined by using the capillary tube system and the micro cylinder system that consists of a rod and a micro capillary tube. A new hydraulic micro actuator using magnetic fluid and an external magnetic field was also investigated. The results showed that our microhydraulic system has the possibility of power transmission in arbitrary directions.

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Study of the Dependency of the Specific Power Absorption Rate on Several Characteristics of the Excitation Magnetic Signal when Irradiating a SPION-containing Ferrofluid

  • Rosales, Alejandra Mina;Aznar, Elena;Coll, Carmen;Mendoza, Ruben A. Garcia;Bojorge, A. Lorena Urbano;Gonzalez, Nazario Felix;Martinez-Manez, Ramon;del Pozo Guerrero, Francisco;Olmedo, Jose Javier Serrano
    • Journal of Magnetics
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    • v.21 no.3
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    • pp.460-467
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    • 2016
  • Magnetic hyperthermia mediated by superparamagnetic particles is mainly based in sinusoidal waveforms as excitation signals. Temperature changes are conventionally explained by rotation of the particles in the surrounding medium. This is a hypothesis quite questionable since habitual experimental setups only produce changes in the magnetic module, not in the field lines trajectories. Theoretical results were tested by changing the waveform of the exciting signal in order to compare non-sinusoidal signals against sinusoidal signals. Experiments were done at different frequencies: 200 KHz, 400 KHz, 600 KHz, 800 KHz and 1 MHz. Superparamagnetic Iron Oxide samples (SPION), made of magnetite ($Fe_3O_4$) and suspended in water (100 mg/ml), were used. Magnetic field strength varies from $0.1{\pm}0.015KA/m$ to $0.6{\pm}0.015KA/m$. In this study was observed that the power loss depends on the applied frequency: for 1 to 2.5 RMS current the responses for each signal are part of the higher section of the exponential function, and for 3.5 to 8 RMS current the response is clearly the decrement exponential function's tale (under $1{\times}10^3LER/gr$).

The Development of Ultrasonic Hyperthermia Simulator to Improve the Efficiency of Ultrasonic Therapy (초음파 치료의 효율성 향상을 위한 초음파 온열 시뮬레이터 개발)

  • Yu, W.J.;Noh, S.C.;Jung, D.W.;Park, J.H.;Choi, M.J.;Choi, H.H.
    • Journal of Biomedical Engineering Research
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    • v.30 no.5
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    • pp.418-427
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    • 2009
  • As many people are westernizing their life style and food consumption habits, a number of patients who have malignant tumors which grow very rapidly and hazardously destroy the human body are increasing. Ultrasonic hyperthermia is not only one of the tumor treatment methods which employs the non-radioactive ultrasonic waves to increase the temperature at the tumor region up to $40\sim45^{\circ}C$ to destroy and suppress tumor cells but also has been proved by many studies. Due to the rapid development of High Intensity Focused Ultrasound(HIFU), the ultrasound hyperthemia extensively boosts its applications in clinical field. For those reasons, Computed simulation factor should be needed before inspection to patients. To prove efficiency of ultrasonic hyperthermia, precise acoustic field measurement considering tissue characteristics and a heating experiment with tissue mimicking material phantom were conducted for effectiveness of simulation program. Finally, in this study, the computer simulation program verified the anticipated temperature effects induced by ultrasound hyperthermia. In the near future, it is hoped that this simulation program could be utilized to improve the efficiency of ultrasound hyperthermia.

Changes in Distribution of Electrical Field in tDCS with Ring Electrode Due to Tissue Anisotropy: a 3D High Resolution Finite Element Head Model Study (경두개직류자극 전기장의 분포 특성에 비등방성 전기 전도율이 미치는 영향 분석 :3차원 고해상도 유한요소 두뇌 모델을 통한 연구)

  • Kim, Sang-Hyuk;Suh, Hyun-Sang;Cho, Young-Sun;Lee, Won-Hee;Kim, Tae-Seong
    • Journal of Biomedical Engineering Research
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    • v.32 no.4
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    • pp.305-311
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    • 2011
  • For effective stimulation with tDCS, spatial focality of induced electrical field(EF) and current density(CD) is one of the important factors to be considered. Recently, there have been some studies to improve the spatial focality via different types of electrodes and their new configurations: some improvements using ring electrodes were reported over the conventional pad electrodes. However, most of these studies assumed isotropic conductivities in the head. In this work, we have investigated the effect of tissue anisotropy on the spatial focality of tDCS with the 4 + 1 ring electrode configuration via a 3-D high-resolution finite element(FE) head model with anisotropic conductivities in the skull and white matter. By examining the profiles of the induced EF from the head models with isotropic and anisotropic conductivities respectively, we found that the spatial focality of the induced EF significantly drops and get diffused due to tissue anisotropy. Our analysis suggests that it is critical to incorporate tissue anisotropy in the effective stimulation of the brain via tDCS.

Experiment of Drifting Mobilities of Holes and Electrons in Stabilized a-Se Film

  • Kang, Sang-Sik;Park, Ji-Koon;Park, Jang-Yong;Kim, Jae-Hyung;Nam, Sang-Hee
    • Transactions on Electrical and Electronic Materials
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    • v.4 no.6
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    • pp.9-12
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    • 2003
  • The electrical properties of stabilized amorphous selenium typical of the material used in direct conversion x-ray imaging devices are reported. Carrier mobility was measured using time-of-flight (TOF) measurements to investigate the transport properties of holes and electrons in stabilized a-Se film. A laser beam with pulse duration of 5 ns and wavelength of 350nm was illuminated on the surface of a-Se with thickness of 400 $\mu\textrm{m}$. The photo induced signals of a-Se film as a function of time were measured. The measured transit times of hole and electron were about 8.73${\mu}\textrm{s}$ and 229.17${\mu}\textrm{s}$, respectively. The hole and electron drift mobilities decreases with increase of electric field up to 4V/$\mu\textrm{m}$. Above 4V/$\mu\textrm{m}$, the measured drift mobilities exhibited no observable dependence with respect to electric field. The experimental results showed that the hole and electron drifting mobility were 0.04584 $\textrm{cm}^2$ V$\^$-1/s$\^$-1/ sand 0.00174 $\textrm{cm}^2$V$\^$-1/s$\^$-1/ at 10 V/$\mu\textrm{m}$.