• 센서학회지
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• 제18권5호
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• pp.402-407
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• 2009

In this study, plastic optical fiber sensors which can measure thermal neutron dose in a mixed neutron-gamma field are developed and characterized. Using $^{252}Cf$ and $^{60}Co$ sources, the scintillators suitable for thermal neutron detection, are tested and the scintillating lights generated from a plastic optical fiber sensor in the Kyoto University Critical Assembly (kuca) core are measured. Also, the distributions of thermal neutron and gamma-ray are measured in a mixed field as a function of the distance from the center of the reactor core at KUCA and the distribution of thermal neutron is obtained using a subtraction method. Sensitivity of the fiber-optic radiation sensor system is about 0.49 V/mW according to power of the KUCA core and its relative error is about 1.2 %.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.121-122
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• 1998

To induce perturbed magnetic field variations in the range of auto prescans permitted, we chose artificially shim values and applied manualy as DC offsets to X, Y, Z gradient amplifiers. The STEAM spectra were obtained from a localized region (8ml) of phantom's center and a Marquart Algorithm is employed to quantify MRS spectra. Results indicated that Creatine (Cr) which had a good correlation between a signal intensity and an area, changed little bit and showed extremly a stabilized state in perturbed magnetic field variations. Therefore, during the MRS experiments, to minimize the SNR reduction by means of unavoidable inhomogeneous magnetic fields, the present study suggested that the quantification method of relative ratios produced by replacing Cr concentration with standard quantify was most desirable.

• Journal of Magnetics
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• 제20권3호
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• pp.290-294
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• 2015

To investigate the effects of alternating magnetic field intensity and stimulation time on the proliferation of human breast cancer cells (BT-20), we cultured the cells under a magnetic field with a saw tooth waveform of 2 kHz. The field intensities varied from 3 to 7 mT, and the stimulation time varied from 24 to 72 hours. Cell proliferation decreased dramatically to 40% during magnetic stimulation for 72 hours at 5 mT. However, the cells were not affected by a strong magnetic field of 7 mT. The p-values obtained using statistical package for social science software were below 0.05 for 5-7 mT. This means that the results have statistical significance. However, it is difficult to explain our results based on the physiology of cell membranes, which have various ionic flows at ion channels.

• Journal of Magnetics
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• 제19권2호
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• pp.155-160
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• 2014

The heating produced by the absorption of radiofrequency (RF) has been considered a secondary undesirable effect during MRI procedures. In this work, we have measured the power absorbed by distilled water, glycerol and egg-albumin during NMR and non-NMR experiments. The samples are dielectric and examples of different biological materials. The samples were irradiated using the same RF pulse sequence, whilst the magnetic field strength was the variable to be changed in the experiments. The measurements show a smooth increase of the thermal power as the magnetic field grows due to the magnetoresistive effect in the copper antenna, a coil around the probe, which is directly heating the sample. However, in the cases when the magnetic field was the adequate for the NMR to take place, some anomalies in the expected thermal powers were observed: the thermal power was higher in the cases of water and glycerol, and lower in the case of albumin. An ANOVA test demonstrated that the observed differences between the measured power and the expected power are significant.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2006년도 제33회 추계학술대회 발표논문집
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• pp.106-106
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• 2006

• 한국광학회지
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• 제18권4호
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• pp.241-245
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• 2007

본 연구에서는 유기 섬광체와 플라스틱 광섬유를 이용하여 치료용 광자선의 계측을 위한 2차원 광섬유 방사선 센서를 제작하였다. 제작된 센서를 사용하여 광자선 조사야(Field size)와 에너지에 따른 선형가속기의 빔 분포도를 2차원적으로 측정하였으며 polymethylmethacrylate(PMMA)팬텀 내에서 깊이에 따른 섬광체의 광량을 측정하여 깊이선량 분포(Percent Depth Dose, PDD) 또한 2차원으로 측정하였다. 본 연구를 통하여 개발된 2차원 광섬유 방사선 센서는 고 분해능, 실시간 측정, 쉬운 보정 등 많은 장점을 가지고 있다.

• 대한의용생체공학회:의공학회지
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• 제31권2호
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• pp.87-93
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• 2010

Researches for stem cells have been focused on scientists in biomedical sciences as well as clinical application for its great therapeutic potentials. Stem cells have two distinct characteristics: self-renewal and differentiation. In this short review, the links between stem cell research and biomedical engineering is discussed based on the basic characteristics of stem cells. This concept can be extended to the fundamental questions of biological sciences for cells such as proliferation, apoptosis, differentiation, and migration. For understanding proliferation and apoptosis of stem cells, techniques from biomedical engineering such as surface patterning, MEMS, nanotechnologies have been used. The advanced technologies such as microfluidic technologies, three dimensional scaffold fabrication, and mechanical/electrical stimulation have also been used in cell differentiation and migration. Basic and unsolved questions in the stem cell research field have limitations by studying conventional technologies. Therefore, the strategic fusion between stem cell biology and novel biomedical engineering field will break the barriers for understanding fundamental questions of stem cells, which can open the window for the clinical applications of stem cell based therapeutics as well as regeneration of damaged tissues.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2004년도 제29회 추계학술대회 발표논문집
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• pp.64-66
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• 2004

디지털 래디오그래피 시스템을 이용하여 환자를 진료하기 위해서는 전처리 과정을 통해 DR 디텍터의 불량화소와 선을 제거하고 offset과 X선의 불균질성을 제거해야만 한다. 불균질성을 제거하기 위해 X-선의 flat field 영상이 필요하며 이는 X선관의 focal spot과 디텍터의 중심과 일치시켜 X선을 디텍터에 수직으로 입사시켜 얻는다. 이러한 영상 촬영구조는 환자를 촬영할 때에도 그대로 유지된다. 하지만 방사선 촬영 기법 중 여러 가지 요인으로 디텍터의 중심과 X선관의 중심을 일치시키지 않거나 디텍터를 기울여 촬영하는 방법들이 있다. 본 연구에서는 디텍터가 기울어져 있거나 또는 임의의 위치에서의 flat field correction 방법의 영향을 분석하고, 새로운 알고리즘을 이용하여 그 영향을 줄이고자 하였다. 본 연구의 결과로 DR 디텍터에서 X선의 flat field를 최대한 보장할 수 있을 것이다.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2000년도 제5차 추계학술대회
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• pp.45-46
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• 2000

• 한국자기공명학회:학술대회논문집
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• 한국자기공명학회 2000년도 동계총회 및 제16회 자기공명 학술발표회
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• pp.32-34
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• 2000