• 한국재료학회:학술대회논문집
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• 한국재료학회 2010년도 춘계학술발표대회
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• pp.38.1-38.1
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• 2010

Nanofibers have a large potential in air filtration applications. In this work, we have developed a photocatalytic polyvinyl alcohol PVA/$TiO_2$ nanofibers membrane for the treatment of air filtration by using electrospinning method. PVA were electrospun into nanofibrous membranes and $TiO_2$ nanoparticles were loaded in PVA nanofibers in various contents from 10% (w/w) to 50% (w/w). The UV-Vis spectra were conducted for testing the existence of $TiO_2$ nanoparticles in PVA fibers. SEM analysis indicated that $TiO_2$ nanoparticles were loaded on the surface of PVA fibers and dispersed linearly along the fiber direction, which originated from the effect of polarization and orientation caused by high electric field. X-ray diffraction (XRD) was used to determine the crystalline of the membrane. Tensile strength was measured to evaluate the physical properties of the membrane. Therefore, our work suggested that PVA/$TiO_2$ nanofiber membrane has a potential application in air filtration area.

• 대한의용생체공학회:의공학회지
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• 제26권6호
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• pp.373-381
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• 2005

The respiratory and heart beat signals are the fundamental physiological signals for sleep monitoring in the home. Using the air mattress sensor system, the respiration and heart beat movements can be measured without any harness or sensor on the subject's body which makes long term measurement difficult and troublesome. The differential measurement technique between two air cells is adopted to enhance the sensitivity. The concept of the balancing tube between two air cells is suggested to increase the robustness against postural changes during the measurement period. With this balancing tube, the meaningful frequency range could be selected by the pneumatic filter method. The mathematical model for the air mattress and balancing tube was suggested and the validation experiments were performed for step and sinusoidal input. The results show that the balancing tube can eliminate the low frequency component between two cells effectively. This technique was applied to measure the respiration and heart beat on the bed, which shows the potential applications for sleep monitoring device in home. With the analysis of the waveform, respiration intervals and heart beat intervals were calculated and compared with the signal from conventional methods. The results show that the measurement from air mattress with balancing tube can be used for monitoring respiration and heart beat in various situations.

• Journal of Plant Biotechnology
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• 제39권4호
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• pp.219-224
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• 2012

Alstroemeria plants are widely cultivated in many countries especially in Western Europe and North America and popularity has increased in recently due to its long-base life, large variety of colors and low energy requirement during cultivation period. So far, more than 60 species have been released on the commercial market in the world. To meet the demand of consumer and develop the elite Alstroemeria cultivars, conventional breeding including cross-hybridization and selection as well as mutation breeding were used. However, as other important ornamental plants such as lily, rose, carnation and orchids accepted the biotechnological methods, this newly-born approach should be applied and developed an optimized the genetic transformation system. Then, this biotechnological approach can be fused with the conventional breeding methods and thus can be contributed to the production of elite Alstroemeria plants containing agriculturally good genetic traits which are useful for the both farmers and consumers in the future. In this paper, we reviewed the botanical and genetical features of Alstroemeria plants and its biotechnological approaches in the last decades.

• Communications for Statistical Applications and Methods
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• 제25권4호
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• pp.373-383
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• 2018

The spatial scan statistic is a widely used method to detect spatial clusters. The method imposes a large number of scanning windows with pre-defined shapes and varying sizes on the entire study region. The likelihood ratio test statistic comparing inside versus outside each window is then calculated and the window with the maximum value of test statistic becomes the most likely cluster. The results of cluster detection respond sensitively to the shape and the maximum size of scanning windows. The shape of scanning window has been extensively studied; however, there has been relatively little attention on the maximum scanning window size (MSWS) or maximum reported cluster size (MRCS). The Gini coefficient has recently been proposed by Han et al. (International Journal of Health Geographics, 15, 27, 2016) as a powerful tool to determine the optimal value of MRCS for the Poisson-based spatial scan statistic. In this paper, we apply the Gini coefficient to normal-based spatial scan statistics. Through a simulation study, we evaluate the performance of the proposed method. We illustrate the method using a real data example of female colorectal cancer incidence rates in South Korea for the year 2009.

• 센서학회지
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• 제18권6호
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• pp.432-440
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• 2009

This paper presents an accelerometer based system for physical activity decision that are capable of recognizing three different types of physical activities, i.e., standing, walking and running, using by rough sets. To collect physical acceleration data, we developed the body sensor node which consists of two custom boards for physical activity monitoring applications, a wireless sensor node and an accelerometer sensor module. The physical activity decision is based on the acceleration data collected from body sensor node attached on the user's chest. We proposed a method to classify physical activities using rough sets which can be generated rules as attributes of the preprocessed data and by constructing a new decision table, rules reduction. Our experimental results have successfully validated that performance of the rule patterns after removing the redundant attribute values are better and exactly same compare with before.

• Macromolecular Research
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• 제17권7호
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• pp.533-537
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• 2009

This paper introduces a modified electro spinning system for biomedical wound-healing applications. The conventional electrospinning process requires a grounded electrode on which highly charged electro spun ultrafine fibers are deposited. Biomedical wound-healing membranes, however, require a very low charge and a low level of remnant solvent on the electrospun membrane, which the conventional process cannot provide. An electrohydrodynamic process complemented with field-controllable electrodes (an auxiliary electrode and guiding electrodes) and an air blowing system was used to produce a membrane, with a considerably reduced charge and low remnant solvent concentration compared to one fabricated using the conventional method. The membrane had a small average pore size (102 nm) and high porosity (85.1%) for prevention of bacterial contamination. In vivo tests on rats showed that these directly electro spun fibrous membranes produced using the modified electro spinning process supported the good healing of skin bums.

• Journal of Ginseng Research
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• 제41권2호
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• pp.215-221
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• 2017

Ginseng has been used in China for at least two millennia and is now popular in over 35 countries. It is one of the world's popular herbs for complementary and alternative medicine and has been shown to have helpful effects on cognition and blood circulation, as well as anti-aging, anti-cancer, and anti-diabetic effects, among many others. The pharmacological activities of ginseng are dependent mainly on ginsenosides. Ginsenosides have a cholesterol-like four trans-ring steroid skeleton with a variety of sugar moieties. Nuclear receptors are one of the most important molecular targets of ginseng, and reports have shown that members of the nuclear receptor superfamily are regulated by a variety of ginsenosides. Here, we review the published literature on the effects of ginseng and its constituents on two main sex steroid hormone receptors: estrogen and androgen receptors. Furthermore, we discuss applications for sex steroid hormone receptor modulation and their therapeutic efficacy.

• Journal of Power Electronics
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• 제16권6호
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• pp.2173-2181
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• 2016

Permanent magnet synchronous motors (PMSMs) have higher torque and superior output power per volume than other types of AC motors. They are commonly used for applications that require a large output power and a wide range of speed. For precise control of PMSMs, knowing the accurate position of the rotor is essential, and normally position sensors such as a resolver or an encoder are employed. On the other hand, the position sensors make the driving system expensive and unstable if the attached sensor malfunctions. Therefore, sensorless algorithms are widely researched nowadays, to reduce the cost and cope with sensor failure. This paper proposes a sensorless algorithm that can be applied to a wide range of speed. The proposed method features a robust operation at low-speed as well as high-speed ranges by employing a gain adjustment scheme and intermittent voltage pulse injection method. In the proposed scheme the position estimation gain is tuned by a closed loop manner to have stable operation in tough driving environment. The proposed algorithm is fully verified by various experiments done with a 1 kW outer rotor-type PMSM.

• JSTS:Journal of Semiconductor Technology and Science
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• 제13권2호
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• pp.108-113
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• 2013

This paper describes a low power asynchronous successive approximation register (SAR) type 12b analog-to-digital converter (ADC) for biomedical applications in a 0.35 ${\mu}m$ CMOS technology. The digital-to-analog converter (DAC) uses a capacitive split-arrays consisting of 6-b main array, an attenuation capacitor C and a 5-b sub array for low power consumption and small die area. Moreover, splitting the MSB capacitor into sub-capacitors and an asynchronous SAR reduce power consumption. The measurement results show that the proposed ADC achieved the SNDR of 68.32 dB, the SFDR of 79 dB, and the ENOB (effective number of bits) of 11.05 bits. The measured INL and DNL were 1.9LSB and 1.5LSB, respectively. The power consumption including all the digital circuits is 6.7 ${\mu}W$ at the sampling frequency of 100 KHz under 3.3 V supply voltage and the FoM (figure of merit) is 49 fJ/conversion-step.

• Biomaterials and Biomechanics in Bioengineering
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• 제3권1호
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• pp.59-69
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• 2016

A surface resisting protein adsorption and cell adhesion is highly desirable for many biomedical applications such as diagnostic devices, biosensors and blood-contacting devices. In this study, a surface conjugated with sulfobetaine molecules was fabricated via the click reaction for the anti-fouling purpose. An alkyne-containing substrate (Alkyne-PPX) was generated by chemical vapor deposition of 4-ethynyl-[2,2]paracyclophane. Azide-ended mono-sulfobetaine molecules were synthesized and then conjugated on Alkyne-PPX via the click reaction. The protein adsorption from 10% serum was reduced by 57%, while the attachment of L929 cells was reduced by 83% onto the sulfobetaine-PPX surface compared to the protein adsorption and cell adhesion on Alkyne-PPX. In conclusion, we demonstrate that conjugation of mono-sulfobetaine molecules via the click chemistry is an effective way for reduction of non-specific protein adsorption and cell attachment.