• Title/Summary/Keyword: Biological value

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Physico-Chemical Properties of Modified Rice Flour by Physical Modification (드럼건조에 의한 쌀가루의 특성)

  • Kum, Jun-Seok;Lee, Hyun-Yu;Shin, Myoung-Gon;Lee, Sang-Hyo;Kim, Kil-Hwan
    • Applied Biological Chemistry
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    • v.37 no.3
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    • pp.154-160
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    • 1994
  • Pregelitinized rice (PR), pregelitinized waxy rice (PWR), and pregelitinized rice flour (PRF) were evaluated for physico-chemical properties comparing with rice starch and acetylated potato starch. L value was decreased during drum drying. PFR had the highest value (P<0.05) for water absorption index and PWR had the highest value for water solubility index. Transmittance of gelitinized samples had drastically increased at $80{\sim}90^{\circ}C$. PWR had the highest value for apparent viscosity and rice samples had a steady apparent viscosity during heating at $90^{\circ}C$. Viscosity was decreased as pH decreased at room temperature and drastically decreased below pH 2. Rice starch and PR had no significant effect for change of pH. Change of viscosity had more effect for hot temp. than room temp.. Pregelitinized samples showed only second peak for DSC. PWR had the lowest value for degree of retrogradation and acetylated potato starch had the highest value for freeze-thaw-stability.

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Isolation and Partial Characterization of Two Ferredoxins from the Photosynthetic Bacterium Heliobacillus mobilis

  • Hatano, Atsushi;Inoue, Kazuhito;Deo, Daisuke;Sakurai, Hidehiro
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.388-390
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    • 2002
  • Two ferredoxin (Fd) fractions, namely, Fd-A and Fd-B were isolated from Heliobacillus mobilis cells, and purified by ammonium sulfate fractionation, DEAE, gel-permeation and Phenyl-Superose column chromatographies under anaerobic conditions. Their absorption spectra were typical of 2[4Fe-4S] cluster type Fds with peaks at about 385 and 280 nm and a shoulder at about 305 nm. Their N-terminal amino acid sequences were determined, which showed that both of them contain a [4Fe-4S] cluster binding motif. Fd-B was sensitive to oxygen, and itsA$_{385}$ value decreased by about 50% in 2 h at 4$^{\circ}C$ under aerobic conditions. In contrast, $A_{385}$ of Fd-A was essentially unchanged up to 24 h under the same conditions.

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Understanding of Clinical Trials and Application to the Real Practice (임상시험의 단계별 이해 및 실제)

  • Choi, SungKu
    • Korean Journal of Biological Psychiatry
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    • v.19 no.4
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    • pp.153-158
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    • 2012
  • Understanding of a clinical trial is essential in developing clinical guideline and adopting evidence based practice. In designing and executing clinical trials, following ethical requirements should be considered : social value, scientific validity, fair subject selection, informed consent, favorable risk-benefit ratio, institutional review board, and respect for human subjects. According to the stage of drug development, purpose of trials, accumulated scientific data, clinical trials for drug development are classified as phase 1, 2, 3, and 4. Phases of clinical trials can be overlapped and the judgment of entering into the next phase should be considered highly strategically. In reading, evaluating and interpreting clinical trial reports, various skills and challenges exist. Patient sample composition, trial duration, selection of endpoints, responders and non-responders, placebo effect, patient recruitment, and extrapolation to the real world are the examples of those challenges. Treatment success will come from the well balanced approach of evidence based decision making and consideration of specific single case.

Ordering Model of Fingerlings in Aquaculture Farm (치어 주문모형에 관한 연구)

  • Eh, Youn-Yang;Song, Dong-Hyo
    • The Journal of Fisheries Business Administration
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    • v.48 no.3
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    • pp.47-59
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    • 2017
  • Fish mortality is the most important success factor in aquaculture management. To order fingerlings considering the effect of mortality is a important problem in aquaculture farm. This study is aimed to decision the number and size of fry in aquaculture farm. This study build the mathematical model that finds the value of decision variable to minimize total cost that sums up the fingerling purchasing cost, aquaculture farm operating cost and feeding cost under mortality constraint. The proposed mathematical model involve biological and economical variables: (1) number of fingerlings (2) fish growth rate (3) mortality (4) price of a fry (5) feeding cost, and (6) possible order period. Numerical simulation model presented here in. The objective of numerical simulation is to provide for decision makers to analyse and comprehend the proposed model. When extensive biological and cost data become available, the proposed model can be widely applied to yield more accurate results.

Biological roles of NAC transcription factors in the regulation of biotic and abiotic stress responses in solanaceous crops

  • Tweneboah, Solomon;Oh, Sang-Keun
    • Journal of Plant Biotechnology
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    • v.44 no.1
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    • pp.1-11
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    • 2017
  • Evolutionary studies conducted on NAC (NAM, ATAF1&2, and CUC2) genes for all major groups of land plants, indicate the presence of the NAC subfamilies, even in the early land plants. The varied roles played by NAC proteins in plant growth and development range from the formation of shoot apical meristem, floral organ development, reproduction, lateral shoot development, and defense responses to biotic and abiotic stresses. Considering the value and importance of solanaceous crops, the study of NAC proteins in these plants needs to be intensified. This will help to identify and functionally characterize their promoters, which will subsequently aid in engineering plants with improved performance under stressful conditions. In this review, the functionally characterized NAC transcription factors specific to tomato, potato, tobacco, chili pepper and eggplant (aubergine) are summarized, clearly indicating their biological functions in the defense mechanism of the plants, against biotic and abiotic stresses.

Characterization of Biological Treatment by an Isolated Phenol-Degrading Bacterium (페놀분해세균의 분리 및 생물학적 처리 특성)

  • 송형의;김진욱
    • Journal of Environmental Health Sciences
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    • v.24 no.3
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    • pp.54-62
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    • 1998
  • 20 bacterial strains capable of growing on phenol minimal medium were isolated from soil and wastewater by the enrichment culture technique, and among them, one isolate which was the best in the cell growth was selected and identified as Bacillus sp. SH3 by its characteristics. Strain SH3 could grow with phenol as the sole carbon source up to 15 mM, but did not grow in minimal medium containing above 20 mM of phenol. The optimal conditions of temperature and initial pH for growth and phenol degradation were 30$^{\circ}$C and 7.5, respectively. This strain could grow on various aromatic compounds such as catechol, protocatechuic acid, gentisic acid, o-, m-, p-cresol, benzoic acid, p-hydroxybenzoic acid, anthranilic acid, phenyl acetate and pentachlorophenol, and the growth-limiting log P value of strain SH3 on organic solvents was 3.1. In batch culture, strain SH3 degraded 97% of 10 mM phenol in 48 hours. In continuous culture under the conditions of 20 mM of influent phenol concentration and 0.050 hr$^{-1}$ of dilution rate, the treatment rate of phenol was 94%.

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Development of a Genistein-enriched Doenjang Using Corn $\beta$-Glucosidase

  • Oh, Jee-Hwan;Suh, Joo-Won;Kim, Jin-Yong;Lee, In-Hyung
    • Food Science and Biotechnology
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    • v.17 no.5
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    • pp.1021-1024
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    • 2008
  • Genistein, one of the isoflavones in doenjang, is generally known to prevent various cancers, osteoporosis, climacterium, and menopause symptoms, and has better bioavailability and healthful physiological effects than its glucoside, genistin. In both traditional and commercial doenjangs, genistein content ranged from 370 to 1,510 mg/kg, however, significant amounts of genistin also existed at the level of 190 to 350 mg/kg. After treating with corn $\beta$-glucosidase, over 84% of genistin in doenjang was converted to genistein. However, physiochemical characteristics such as pH, viscosity, 2-thiobarbituric acid (TBA) value, and color were not changed significantly after corn $\beta$-glucosidase treatments. Therefore, this study shows that the improved doenjang with the increased genistein content can be produced using corn $\beta$-glucosidase.

Attention and Psychiatric Disorders (주의력과 정신장애)

  • Ha, Kyoo-Seob;Kang, Ung Gu;Kim, Jong-Hoon
    • Korean Journal of Biological Psychiatry
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    • v.4 no.1
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    • pp.19-23
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    • 1997
  • Attention is a phenomenon hard to define, but can be conceptualized as a mental function ranging from sustaining readiness to perceive stimuli to understanding the nature and value and selecting stimuli that are most relevant to the given situation. Manifestations of attention include vigilance, and focused, directed, selective, divided, and sustained attentions. While basic attentional tone is controlled by the interaction among reticular activating system, thalamus and prefrontal cortex, direction and selection of attention is controlled by neural circuits of prefrontal, posterior parietal, and limbic cortex. It is expected that understanding of attention and its neural control could provide answers to the relationship between pathophysiology and clinical symptoms of some major psychiatric disorders. More efforts are required to develop tools to assess more detailed and various aspects of attention in Korea.

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Isolation and Characterization of $\alpha$-Glucosidase Inhibitor from the Fungus Ganoderma lucidum

  • Kim, Shin-Duk;Nho, Hong Joon
    • Journal of Microbiology
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    • v.42 no.3
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    • pp.223-227
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    • 2004
  • An ${\alpha}$-glucosidase inhibitor, SKG-3, was isolated from the fruiting bodies of Ganoderma lucidum and its physico-chemical properties were characterized. It was a highly specific and effective reversible inhibitor of ${\alpha}$-glucosidase. It showed very potent inhibitory activity against a-glucosidase with an IC$\sub$50/ value of 4.6$\mu\textrm{g}$/$m\ell$, but no activity for any other glycosidases tested. Enzyme activity could be recovered upon dialysis, thus providing evidence for the reversibility of the inhibition. A Lineweaver-Burk plot indicated that the SKG-3 inhibition of ${\alpha}$-glucosidase was competitive.

A Study of Cleaning on the Biofilm of Stone Cultural Properties (석조문화재 생물막 제거 및 처리방안 연구)

  • Chung, Yong-Jae;Seo, Min-Seok;Lee, Kyu-Shik;Hwang, Jin-Ju
    • 보존과학연구
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    • s.26
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    • pp.5-25
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    • 2005
  • A consideration number of investigation have begun to elucidate the essential role biological agents play in the deterioration of stone. What is becoming clear is that many factors affect the durability of stone. Physical, chemical, and biological agentsact in co-association, ranging from synergistic to antagonistic, to deteriorate stone. Biodeterioration has usually been considered to be a degradation process following the initial deterioration effects of inorganic agents, especially objects of cultural value such as pagoda, stature of Buddha etc. These agents were thought to condition stone surfaces for microbial contamination due to structural changes and enrichment of inorganic organic nutrient substrates. This report concentrates on the action of biodeteriogens from bacteria to algae and higher plants. Preventive and remedial methods are surveyed, as are a selection of chemical treatments.

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