• Korean Journal of Fisheries and Aquatic Sciences
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• v.50 no.4
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• pp.437-446
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• 2017

To evaluate the consequences of possible fisheries regulations of anchovy Engraulis japonicus in the Korea Strait, we developed and applied a simulation-based yield-per-recruit (Y/R) model that considered temperature-dependent growth and size-dependent mortality, covering the egg to adult stages. We projected changes in commercial yield and egg production of anchovy with respect to varying biological reference points of 1) the instantaneous fishing mortality, 2) the minimum fork length of anchovy allowed to catch for protecting smaller anchovy ($L_{c,min}$), and 3) the maximum fork length allowed to catch for protecting bigger anchovy ($L_{c,max}$). Our Y/R model showed that the anchovy yield will be maximized at ca. $1.4{\times}10^6tons$ when $L_{c,min}$ ranges between 42-60 mm or at ca. $0.8{\times}10^6tons$ when $L_{c,max}$ ranges from 88-160 mm. At $L_{c,min}=30mm$, the present minimum length of catch, our simulations indicated that the anchovy yield can reach a maximum of $1.2{\times}10^6tons$ in the long-term when the present fishing effort, which annually yields ca. $0.2{\times}10^6tons$ of anchovy, can be increased by a factor of 28. We expect that our simulation-based Y/R model can be applied to other commercially-important small pelagic species in which the traditional Beverton-Holt Y/R model is difficult to apply.

• Proceedings of the Korean Society of Rheology Conference
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• 2006.06a
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• pp.81-84
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• 2006

Slot coating process, in continuous and patch modes, has been applied for the many precise coating products, e.g., flat panel displays and second batteries. However, manufacturing uniform coating products is not a trivial task at high-speed operations because various flow instabilities or defects such as leaking, bubbles, ribbing, and rivulets are frequently observed in this process. It is no wonder, therefore, that many efforts to understand the various aspects of dynamics and coating windows of this process have been made both in academia and industry. In this study, as the first topic, flow dynamics within the coating bead in slot coating process has been investigated using the one-dimensional viscocapillary model by lubrication approximation and two-dimensional model by Flow-3D software. Especially, operability windows in both 1D and 2D cases with various slot die lip designs have been successfully portrayed. Also, effects of process conditions like viscosity and coating gap size on slot coating window have been analyzed. Also, some experiments to find minimum coating thickness and coating windows have been conducted using slot die coater implemented with flow visualization device, corroborating the numerical results. As the second topic, flow dynamics of both Newtonian and Non-Newtonian fluids in patch or pattern slot coating process, which is employed in manufacturing IT products such as secondary batteries, has been investigated for the purpose of optimal process designs. As a matter of fact, the flow control in this system is more difficult than in continuous case because od its transient or time-dependent nature. The internal die and die lip designs for patterned uniform coating products have been obtained by controlling flow behaviors of coating liquids issuing from slot. Numerical simulations have been performed using Fluent and Flow-3D packages. Flow behavior and pressure distribution inside the slot die has been compared with various die internal shapes and geometries. In the coating bead region, efforts to reduce irregular coating defects in head and tail parts of one patterned coating unit have been tried by changing die lip shapes. It has been concluded that optimal die internal design gas been developed, guaranteeing uniform velocity distribution of both Newtonian and shear thinning fluids at the die exit. And also optimal die lip design has been established, providing the longer uniform coating layer thickness within one coating unit.

• Journal of Integrative Natural Science
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• v.10 no.2
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• pp.78-84
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• 2017

CXC chemokine receptor 2 (CXCR2) is a prominent chemokine receptor on neutrophils. CXCR2 antagonist may reduce the neutrophil chemotaxis and alter the inflammatory response because the neutrophilic inflammation in the lung diseases is found to be largely regulated through CXCR2 receptor. Hence, in the present study, Hologram based Quantitative Structure Activity Relationship Study was performed on a series of CXCR2 antagonist named pyrimidine-5-carbonitrile-6-alkyl derivatives. The best HQSAR model was obtained using atoms, bonds, and chirality as fragment distinction parameter using hologram length 151 and 6 components with fragment size of minimum 4 and maximum 7. Significant cross-validated correlation coefficient ($q^2=0.774$) and non cross-validated correlation coefficients ($r^2=0.977$) were obtained. The model was then used to evaluate the six external test compounds and its $r^2_{pred}$ was found to be 0.614. Contribution map show that presence of cyclopropyl ring and its bulkier substituent's makes big contributions for improving the biological activities of the compounds. We hope that our HQSAR model and analysis will be helpful for future design of novel and structurally related CXCR2 antagonists.

• Journal of Integrative Natural Science
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• v.11 no.2
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• pp.93-100
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• 2018

Caspases, a family of cysteinyl aspartate-specific proteases plays a central role in the regulation and the execution of apoptotic cell death. Caspase-3 has been proven to be an effective target for reducing the amount of cellular and tissue damage because the activation of caspases-3 stimulates a signalling pathway that ultimately leads to the death of the cell. In this study, Hologram based Quantitative Structure Activity Relationship (HQSAR) models was generated on a series of Caspase-3 inhibitors named 3, 4-dihydropyrimidoindolones derivatives. The best HQSAR model was obtained using atoms, bonds, and hydrogen atoms (A/B/H) as fragment distinction parameter using hologram length 61 and 3 components with fragment size of minimum 5 and maximum 8. Significant cross-validated correlation coefficient ($q^2=0.684$) and non cross-validated correlation coefficients ($r^2=0.754$) were obtained. The model was then used to evaluate the eight external test compounds and its $r^2_{pred}$ was found to be 0.559. Contribution map show that presence of pyrrolidine sulfonamide ring and its bulkier substituent's makes big contributions for improving the biological activities of the compounds.

• Journal of the Korea Convergence Society
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• v.8 no.8
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• pp.197-202
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• 2017

Three-dimensional melanin granules of mummy's hair analyzed using high voltage electron microscopy at 1250kV. The melanin granules in the cortex of mummy's hair located in close proximity to the outer of cortex in the adjacent place of the cuticles. A lot of melanin granule performed in this area. It is a distinguished difference from modern human. While it rotated up to 60 degree counter-clockwise and taken a photo per one degree using high voltage electron microscopy. The melanin granule displayed with long elliptical and variable at the size. The size of granule is measured from $0.3{\sim}0.6{\mu}m$ in minimum diameter and $0.5{\sim}1{\mu}m$ in maximum diameter. Conclusionally, high voltage electron microscope has higher resolution and penetration power than conventional transmission electron microscope that could be load biological thick specimen.

• Journal of the Korean Institute of Landscape Architecture
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• v.40 no.6
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• pp.140-147
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• 2012

This study was conducted to investigate optimum planting density for apartment complex. The validity of Landscape Architecture Criteria of Korea was checked for it. We compared our field data with Landscape Architecture Criteria. In this step, the tree density of urban forest was regarded as standard. Field study was examined in 3 apartment complexes located in capital area, especially completed during these 10 years. 10 sites in each complex were selected and tree density per unit area were calculated. This field study data was divided standard size and large size which received weight. And, it was compared and analyzed. And crown projected area(CPA) was calculated considering proper growth of low vegetation and sufficient shade. The outcome shows that minimum size of Landscape Architecture Criteria is rational. But, in the case of planting large size tree received weight, tree density was short comparing with the tree density of urban forest and CPA was less than 50%. By the result of field study in 3 apartment complex, the tree density of apartment complex satisfied or exceeded Landscape Architecture Criteria. But, in the case of planting large size tree, tree density and CPA show high density due to addition planting for deficient landscape. Therefore, the revision of the Landscape Architecture Criteria was required such as deletion or minimization of the weighted clause about the large size tree and regulate the limit CPA not less than 50% and not more than 100%.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.5 no.3
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• pp.83-87
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• 1972

The fresh-water shrimp, Macrobrachium nipponensis (DE HAAN) is one of the largest of the shrimp species and one of the most important types fo protein food in fresh water fisheries. It can be found from Cheju island in the touth to Chung-ju in river or swamp, in the north. The breeding of these shrimps was studied by Chun and Yu (1967) and the relative growth was reported by author (1970a), but they did'nt provide other ecological features widely found in their natural environment. Shrimps were collected from the Nak Dong River, near Pusan, Korea once a month, from March to December 1963. The following is a summary of the results. 1. Larvae hatch from May to September, mainly in the month of July. 2. The average sex ratio ($male/female{\times}100$) is $62.9\%$ and goes down during the spawning season and rises from fall to spring season. 3. The minimum size of the female with eggs is aproximately 4.2cm in body length 3.5 gr in body weight, and 1.5 cm in carapace length. 4. Most shrimps of 5.75-7.75 cm in body length lay eggs. 5. The dorsal spines of the rostrum are 10-16(mode13) in number and the ventral spines of the rostrum are 1-5 (mode 3) in number.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1429-1434
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• 2014

Background: Owing to the variability of histopathological features and biological behaviour in gastric carcinoma, a great number of categorisation methods such as classical histopathologic grading, Lauren classification, the TNM staging system and the newly presented Goseki grading method are used by pathologists and other scientists. In our study, we aimed to investigate whether Goseki grade and tumour location have an effects on survival of gastric cancer cases. Materials and Methods: Eighty-four patients with gastric adenocarcinoma were covered in the investigation. The importance of Goseki grading system and tumour location were analysed in addition to the TNM staging and other conventional prognostic parameters. Results: The median survival time in our patients was 35 months (minimum: 5, maximum: 116). According to our findings, there was no relation between survival and tumour size (p=0.192) or classical histological type (p=0.270). In contrast, the Goseki grade and tumour location significantly correlated with survival (p=0.007 and p<0.001, respectively). Additionally, tumours of the intestinal type had a longer median survival time (60.0 months) than diffuse tumours (24.0 months). Conclusions: In addition to the TNM staging system, tumour location and the Goseki grading system may be used as significant prognostic parameters in patients with gastric cancer.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.38 no.4
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• pp.251-256
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• 2005

For blood cockle Tegillarca granosa acclimated to winter and summer seasons, survival, temperature tolerance and physiological changes at different individual size were investigated for their temperature tolerances by increasing and decreasing temperature at a rate of 1, 2 and $3^{\circ}C/day$. The survival rate of adults and juveniles T. granosa acclimated to winter temperatures began to decrease from $32^{\circ}C$ and all experimental animals died between $37-39^{\circ}C$. In the case of animals acclimated to summer temperatures, the survival rates of adults and juveniles began to decrease from $35^{\circ}C$, and all died at temperatures between $40-44^{\circ}C$. The upper $LT_{50}$ was $27.72^{\circ}C$ for adults and $28.36^{\circ}C$ for juveniles. On the other hand, when the temperature was decreased from $4^{\circ}C\;to\;0^{\circ}C$ in order to investigate lower temperature tolerances, the survival rate of T. granosa was more than $70\%\;at\;2^{\circ}C$ for 25 days. Lower L T 50 was $2.09^{\circ}C$ for adults and $2.34^{\circ}C$ for juveniles. There was no effective difference in temperature tolerance between adults and juveniles. Filtration and respiration rates of T. granosa showed a similar aspect with increase and decrease of temperature. Filtration and respiration rates exhibited irregular conditions of a broken biological rhythm as the group acclimated to winter $(10 ^{\circ}C)$ and summer $(25^{\circ}C)$. In the case of decreasing temperature, filtration and respiration rates of T. granosa reduced to a minimum below $6^{\circ}C$

• Membrane and Water Treatment
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• v.11 no.4
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• pp.257-274
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• 2020

There are many previous review articles are available to summarize either the characterization methods of effluent organic matter (EfOM) or the individual control treatment options. However, there has been no attempt made to compare in parallel the physicochemical treatment options that target the removal of EfOM from biological treatments. This review deals with the recent progress on the characterization of EfOM and the novel technologies developed for EfOM treatment. Based on the publications after 2010, the advantages and the limitations of several popularly used analytical tools are discussed for EfOM characterization, which include UV-visible and fluorescence spectroscopy, Fourier transform infrared spectroscopy (FTIR), size exclusion chromatography (SEC), and Fourier transform-ion cyclotron resonance-mass spectrometry (FT-ICR-MS). It is a recent trend to combine an SEC system with various types of detectors, because it can successfully track the chemical/functional composition of EfOM, which varies across a continuum of different molecular sizes. FT-ICR-MS is the most powerful tool to detect EfOM at molecular levels. However, it is noted that this method has rarely been utilized to understand the changes of EfOM in pre-treatment or post-treatment systems. Although membrane filtration is still the preferred method to treat EfOM before its discharge due to its high separation selectivity, the minimum requirements for additional chemicals, the ease of scaling up, and the continuous operation, recent advances in ion exchange and advanced oxidation processes are greatly noteworthy. Recent progress in the non-membrane technologies, which are based on novel materials, are expected to enhance the removal efficiency of EfOM and even make it feasible to selectively remove undesirable fractions/compounds from bulk EfOM.