• 제목/요약/키워드: Biological information

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Development of Biological Cell Manipulation System using Visual Tracking Method

  • Lee, Geunho;Kang, Hyun-Jae;Kwon, Sang-Joo;Park, Gwi-Tae;Kim, Byungkyu
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2003년도 하계종합학술대회 논문집 V
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    • pp.2911-2914
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    • 2003
  • Conventionally, biological manipulations have been performed manually with long training and pretty low success rates. To overcome this problem, a novel biological manipulation system has been developed to manipulate biological cells without any interference of a human operator, In this paper, we demonstrate a development of tole-autonomous Cell Manipulation System (CMS) using an image processing at a remote site. The CMS consists of two manipulators, a plane stage, and an optical microscope. We developed deformable template-model-matching algorithm for micro objects and pattern matching algorithm of end effect for these manipulators in order to control manipulators and the stage. Through manipulation of biological cells using these algorithms, the performance of the CMS is verified experimentally.

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섭식장애의 생물학적 및 정서적 병인기전에 대한 새로운 지견 (New Insights on the Biological and Emotional Pathogenesis of Eating Disorders)

  • 김율리
    • 생물정신의학
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    • 제20권3호
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    • pp.74-79
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    • 2013
  • Objectives This paper aims to understand the emotional-biological pathogenesis of eating disorders, and translate the understanding into new brain directed treatments. Methods The first part of the review sets the eating behavior into the context of what is now understood about the central control of appetite and molecular biology. The second part of the review sees how emotion relates to the brain circuit involving eating disorders. Results In general, patients with anorexia nervosa restricting type were less sensitive to reward, whereas patients with bulimia nervosa and anorexia nervosa binge purging type were more sensitive to it. The emotional life of people with eating disorders centers on food, weight, and shape. The abnormalities in social and emotional functioning both precede and persist outside of eating disorders. Conclusions Research into understanding the biological framework of the brain in eating disorders suggests that abnormalities may exist in emotional and information processing. This aspect can be translated into novel brain-directed treatments, particularly in anorexia nervosa.

A novice’s guide to analyzing NGS-derived organelle and metagenome data

  • Song, Hae Jung;Lee, JunMo;Graf, Louis;Rho, Mina;Qiu, Huan;Bhattacharya, Debashish;Yoon, Hwan Su
    • ALGAE
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    • 제31권2호
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    • pp.137-154
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    • 2016
  • Next generation sequencing (NGS) technologies have revolutionized many areas of biological research due to the sharp reduction in costs that has led to the generation of massive amounts of sequence information. Analysis of large genome data sets is however still a challenging task because it often requires significant computer resources and knowledge of bioinformatics. Here, we provide a guide for an uninitiated who wish to analyze high-throughput NGS data. We focus specifically on the analysis of organelle genome and metagenome data and describe the current bioinformatic pipelines suited for this purpose.

The vertebrate fauna along the Hantangang (river) of Korea

  • Jo, Yeong-Seok;Kim, Byung-Jik;Hur, Wee-Haeng;Won, Chang-Man
    • Journal of Species Research
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    • 제1권1호
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    • pp.87-99
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    • 2012
  • Before the construction of Hantangang dam, we surveyed vertebrate fauna along the Hantangang River and collected samples. We collected 248 specimens (1,394 individuals) of 41 fish species from 10 families in four orders, including 17 endemic species and 5 endangered species. In our herpetofauna survey, we collected 47 amphibian samples of 10 species from 5 families in 2 orders, and 19 reptile samples of 5 species from 2 families in 1 order. We observed 25 species of bird (6 orders, 14 families) inclulding collection of 51 bird specimens (10 species from 5 families in 1 order). We collected 91 mammals of 6 species, and identified 7 species from field sign and direct observation from a total of 10 families in 5 orders. This collection and list comprise the final vertebrate faunal survey of the Hantangang region, and will provide basic scientific information for future research on conservation and restoration of the region.

A considerable review on type specimens of Korean vascular plants in the Herbarium of the Komarov Botanical Institute (LE) Addition

  • Grabovskaya-Borodina, Alisa E.;Illarionova, Irina D.;Jang, Hyun-Do;Lee, Byoungyoon;Suh, Min Hwan;Park, Jeong Mi
    • Journal of Species Research
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    • 제7권1호
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    • pp.73-79
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    • 2018
  • The review provides the information about 46 type specimens on 35 taxa of vascular plants from Korea (Fig. 1), kept in the Herbarium of the Komarov Botanical Institute of the Russian Academy of Sciences in addition to 150 taxa published before. Lectotype of Ligustrum patulum Palib is designated here.

북한 생물정보 DB 구축에 의한 남북한 동·식물명 비교 연구 (A Comparative Study on Zoology & Botany Name of South and North Korea Building Bio-information Database of North Korea)

  • 김남신;김석주;김영화;정성희
    • 한국환경복원기술학회지
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    • 제22권6호
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    • pp.27-39
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    • 2019
  • The object of this research is to compare zoology and botany name caused by language and science differences of South and North Korea since division. Biological data are collected North Korea biological information (flora and fauna, an illustrated flora and fauna book of North Korea, Etc.) and compared both side data based on national species list of korea, National Institute of Biological Resources. We could built 3,903 species of flora and 1,487 species flora on biological database. The criteria for comparative method is 5 types (korean name difference, scientific name difference, same species, similar species, North Korea endemic species). As a results, plants were identified korean name difference (911 species), scientific name difference (614 species), same species (880 species), North Korea endemic species (1,037 species) of 3,903 species, and animals were korean name difference (685 species), scientific name difference (104 species), same species (199 species), North Korea endemic species (226 species) of the 1,492 species. This results are expected to be in application with cooperation study for recovering bioinformatics differences of South and North Korea.

Effects of Quorum Quenching on the Microbial Community of Biofilm in an Anoxic/Oxic MBR for Wastewater Treatment

  • Jo, Sung Jun;Kwon, Hyeokpil;Jeong, So-Yeon;Lee, Sang Hyun;Oh, Hyun-Suk;Yi, Taewoo;Lee, Chung-Hak;Kim, Tae Gwan
    • Journal of Microbiology and Biotechnology
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    • 제26권9호
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    • pp.1593-1604
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    • 2016
  • Recently, bacterial quorum quenching (QQ) has been proven to have potential as an innovative approach for biofouling control in membrane bioreactors (MBRs) for advanced wastewater treatment. Although information regarding the microbial community is crucial for the development of QQ strategies, little information exists on the microbial ecology in QQ-MBRs. In this study, the microbial communities of biofilm were investigated in relation to the effect of QQ on anoxic/oxic MBRs. Two laboratory-scale MBRs were operated with and without QQ-beads (QQ-bacteria entrapped in beads). The transmembrane pressure increase in the QQ-MBRs was delayed by approximately 100-110% compared with conventional- and vacant-MBRs (beads without QQ-bacteria) at 45 kPa. In terms of the microbial community, QQ gradually favored the development of a diverse and even community. QQ had an effect on both the bacterial composition and change rate of the bacterial composition. Proteobacteria and Bacteroidetes were the most dominant phyla in the biofilm, and the average relative composition of Proteobacteria was low in the QQ-MBR. Thiothrix sp. was the dominant bacterium in the biofilm. The relative composition of Thiothrix sp. was low in the QQ-MBR. These findings provide useful information that can inform the development of a new QQ strategy.

지자기 센서를 이용한 양이 보청기의 방향성 이득 조절 연구 (Automatic Directional-gain Control for Binaural Hearing Aids using Geomagnetic Sensors)

  • 양혜진;안선영;정재현;최인용;우지환
    • 대한의용생체공학회:의공학회지
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    • 제37권6호
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    • pp.209-214
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    • 2016
  • Binaural hearing aids with a voice transmitter have been widely used to enhance sound quality in noisy environment. However, this system has a limitation on sound-source localization. In this study, we investigated automatic directional-gain control method using geomagnetic sensors to provide directional information to binaural hearing aid user. The loudness gains of two hearing aids were differently controlled based on the directional information between a speaker position and a viewing direction of hearing aids user. This relative directional information was measured by two geomagnetic sensors on hearing aids user and a speaker. The results showed that the loudness gains were accurately controlled and could provide directional information based on the cue of interaural level differences.

데이터 퓨전을 이용한 얼굴영상 인식 및 인증에 관한 연구 (2D Face Image Recognition and Authentication Based on Data Fusion)

  • 박성원;권지웅;최진영
    • 한국지능시스템학회논문지
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    • 제11권4호
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    • pp.302-306
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    • 2001
  • 얼굴인식은 이미지의 많은 변동(표정, 조명, 얼굴의 방향 등)으로 인해 한 가지 인식 방법으로는 높은 인식률을 얻기 어렵다. 이러한 어려움을 해결하기 위해, 여러 가지 정보를 융합시키는 데이터 퓨전 방법이 연구되었다. 기존의 데이터 퓨전 방법은 보조적인 생체 정보(지문, 음성 등)를 융합하여 얼굴인식기를 보조하는 방식을 취하였다. 이 논문에서는 보조적인, 생체 정보를 사용하지 않고, 기존의 얼굴인식방법을 통해 얻어지는 상호보완적인 정보를 융합하여 사용하였다. 개별적인 얼굴인식기의 정보를 융합하기 위해, 전체적으로는 Dempster-Shafer의 퓨전이론에 근거하면서, 핵심이 되는 질량함수를 새로운 방식으로 재정의학 퓨전모델을 제안하였다. 제안된 퓨전모델을 사용하여 개별적인 얼굴인식기의 정보를 융합한 결과, 보조적인 생체정보 없이, 개별적인 얼굴인식기보다 나은 인식률을 얻을 수 있었다.

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프로모터 염기서열 분석을 위한 데이터 마이닝 기법 (Data Mining Techniques for Analyzing Promoter Sequences)

  • 김정자;이도헌
    • 한국정보통신학회:학술대회논문집
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    • 한국해양정보통신학회 2000년도 추계종합학술대회
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    • pp.328-332
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    • 2000
  • 최근 지놈(Genome) 프로젝트를 통해 DNA 염기서열에 대한 정보가 밝혀짐에 따라 분자 수준의 유전자 정보를 다루는 기법이 활발히 연구되고 있다. 그리고 밝혀진 서열정보들의 방대함으로 미루어볼 때 이들 정보를 데이터베이스화하고 효과적인 분석을 행하기 위한 새로운 컴퓨터의 알고리즘의 개발 또한 시급한 일이다. 이러한 측면에서 ,본 논문에서는 분자생물학에서 매우 중요한 연구 대상으로 삼고있는 프로모터 서열과 유전자간의 연관성으로 발현되는 특징을 알아내기 위한 연관 규칙 탐사 알고리즘을 연구한다. 기존의 탐사 알고리즘은 트랜잭션 데이터를 대상으로 하지만 본 논문에서는 생물학적 데이터를 대상으로 하였기 때문에 데이터의 형태와 생물학적인 특성을 수용하는 변형된 연관규칙 알고리즘을 설계한다. 본 연구를 통하여 얻어진 결과는 실제 생물학적 실험'대상의 후보조합을 최소화 하므로써 많은 시간과 노력 비용을 절감할 수 있다.

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