• Journal of Environmental Impact Assessment
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• v.10 no.1
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• pp.73-83
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• 2001

Web based integrated sewer management system was developed for the analysis of sewer flow and for the optimal operation of sewer works using ArcView and SWMM. SWMM and ArcView were dynamically linked together using Avenue in order to construct user-friendly information management system. The developed system was applied to the residential area in Choonchun city to verify its utilities. All the relevant field data were analyzed on the basis of the developed system, and the modeling of sewer flow was implemented using RUNOFF, EXTRAN, TRANSPORT in SWMM. This system is now in the process of connection to the management system of stormwater, surface and subsurface environment in order to develop an integrated environmental management system. Futhermore, this system will be a critical part of overall control system of sewer works including sewer network and wastewater treatment plant. As this system can provide comprehensive prediction of flow and pollution profiles, it could serve as a tool not only for the optimal management, but also for the decision support system to examine the efficiency of planning and implementation of sewer projects.

• Animal Systematics, Evolution and Diversity
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• v.31 no.3
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• pp.160-175
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• 2015

The echolocation calls of bats can provide useful information about species that are generally difficult to observe in the field. In many cases characteristics of call structure can be used to identify species and also to obtain information about aspects of the bat's ecology. We describe and compare the echolocation call structure of 14 of the 21 bat species found in Korea, for most of which the ecology and behavior are poorly understood. In total, 1,129 pulses were analyzed from 93 echolocation call sequences of 14 species. Analyzed pulses could be classified into three types according to the pulse shape: FM/CF/FM type, FM type and FM/QCF type. Pulse structures of all species were consistent with previous studies, although geographic variation may be indicated in some species. Overall classification rate provided by the canonical discriminant analysis was relatively low. Especially in the genera Myotis and Murina, there are large overlaps in spectral and temporal parameters between species. On the other hand, classification rates for the FM/QCF type species were relatively high. The results show that acoustic monitoring could be a powerful tool for assessing bat activity and distribution in Korea, at least for FM/QCF and FM/CF/FM species.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.2
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• pp.447-452
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• 2013

Microfluidic devices can offer precise control for a verity of tasks involving biological specimen. In this paper, we propose an integrated system consisting of a microfluidic device along with a digital holographic microscope and present three-dimensional (3D) sensing and segmentation of biological microorganisms. When the individual microorganisms are inputted into the microfluidic channel, the holographic microscope records their holograms. The holograms are computationally reconstructed in 3D using Fresnel transform and the reconstructed phase images are used to search the position of microorganisms. Optical experiments are carried out and experimental results are presented to illustrate the usefulness of the proposed system.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.5 no.1
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• pp.45-51
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• 2012

In this paper, it's a system which recognize the user's emotions after obtaining the biological informations(pulse sensor, blood pressure sensor, blood sugar sensor etc.) about user's bio informations through wireless sensors in accordance of previously collected informations about user's stress index and classification the Colors & Music. This system collects the inputs, saves in the database and finally, classifies emotions according to the stress quotient by using multiple SVM(Support Vector Machine) algorithm. The experiment of multiple SVM algorithm was conducted by using 2,000 data sets. The experiment has approximately 87.7% accuracy.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.429-431
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• 2002

Metabolic analysis of biological tissues, the interventional radiology in MRT (Magnetic Resonance Treatment) and for clinical diagnoses, representation of 4-Dimensional (4D) structural information (x,y,z,t) of biological tissues is required. This paper discusses image representation techniques for those 4D MR Images. We have proposed an image reconstruction method for ultra-fast 3D MRI. It is based on image interpolation and prediction of un-acquired pictorial data in both of the real and the k-space (the acquisition domain in MRI). A 4D MR image is reconstructed from only two 3D MR images and acquired a few echo signals that are optimized by prediction of the tissue motion. This prediction can be done by the phase of acquired echo signal is proportioned to the tissue motion. On the other hand, reconstructed 4D MR images are represented as a 3D-movie by using computer graphics techniques. Rendered tissue surfaces and/or ROIs are displayed on a CRT monitor. It is represented in an arbitrary plane and/or rendered surface with their motion. As examples of the proposed representation techniques, the finger and the lung motion of healthy volunteers are demonstrated.

• Journal of the Korea Society of Computer and Information
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• v.22 no.3
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• pp.131-138
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• 2017

New drug development is time-consuming and costly. Hence, it is necessary to repurpose old drugs for finding new indication. We suggest the way that repurposing old drug using massive literature data and biological network. We supposed a disease-drug relationship can be available if signal pathways of the relationship include significant genes identified in literature data. This research is composed of three steps-identifying significant gene using co-occurrence in literature; analyzing the shortest path on biological network; and scoring a relationship with comparison between the significant genes and the shortest paths. Based on literatures, we identify significant genes based on the co-occurrence frequency between a gene and disease. With the network that include weight as possibility of interaction between genes, we use shortest paths on the network as signal pathways. We perform comparing genes that identified as significant gene and included on signal pathways, calculating the scores and then identifying the candidate drugs. With this processes, we show the drugs having new possibility of drug repurposing and the use of our method as the new method of drug repurposing.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.99-99
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• 2017

Chili pepper (Capsicum annum) is origin of subtropical region, and has been spread all over the world. It is increasing the production and consumption in recent year. Chili peppers are readily incorporated into local South Asian cuisines perhaps because people are already familiar with pungent and spicy flavors. Chili peppers, despite their fiery "hotness", are one of very popular spices known for their medicinal and health benefiting properties. Especially in South East Asia, they grow up so many cultivars of them recently, so it is so important crop world wide. In South East Asia, there are some articles about chili pepper in Thailand and Indonesia, but in Vietnam there is not so much information about chili pepper. In this paper, we analyzed genetic diversity in Vietnamese Chili pepper through the survey of local chili pepper. As a result, we got 38 kinds of chili fruits, 26 kinds of leaves and some information from farmers all in Vietnam. And I made the phylogenetic tree by SSR with 10 DNA markers. Finally we found the genetic similarities by regions.

• Interdisciplinary Bio Central
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• v.3 no.3
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• pp.12.1-12.3
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• 2011

Bioinformatics tools and databases are useful for understanding and processing various biological data. Numerous resources are being published each year. It is not a trivial task to find up-to-date relevant tools and databases. Moreover, no server is available to provide comprehensive coverage on bioinformatics resources in all biological fields. Here, we present a directory server called IntoPub that provides information on web resources. First, we downloaded XML-formatted abstracts containing web URLs from the NCBI PubMed database by using 'ESearch-EFetch' function in the NCBI E-utilities. The information is obtained from abstracts in the PubMed by extracting 'www' or 'http' prefixes. Then, we cu-rate the downloaded abstracts both in automatic and manual fashion. As of July 2011, the IntoPub database has 12,118 abstracts containing web URLs from 174 journals. Our anal-ysis shows that the number of abstracts containing web resources has increased signifi-cantly every year. The server has been tested by many biologists from several countries to get opinion on user satisfaction, usefulness, practicability, and ease of use since January 2010. In the IntoPub web server, users can easily find relevant bioinformatics resources, as compared to searching in PubMed. IntoPub will continue to update and incorporate new web resources from PubMed and other literature databases. IntoPub, available at http://into.kobic.re.kr/, is updated every day.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.7
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• pp.1709-1714
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• 2013

Biological and chemical processes in the refining process can include several steps of chromatographic separation processes. Recently, with the development of biotechnology is important to a lot of attention has been paid to the process in Adsorption chromatography for the separation of biological molecules such as proteins. Therefore, in this paper, we have designed and implemented a simulation system for adsorption process modeling. This system appear visualization for simulation result or curve graph according to adsorption process modeling. The development of this system has been developed to focus on the batch adsorption process simulation program, is limited.

• Applied Microscopy
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• v.46 no.3
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• pp.134-139
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• 2016

Detailed structural and molecular imaging of intact organs has incurred academic interest because the associated technique is expected to provide innovative information for biological investigation and pathological diagnosis. The conventional methods for volume imaging include reconstruction of images obtained from serially sectioned tissues. This approach requires intense manual work which involves inevitable uncertainty and much time to assemble the whole image of a target organ. Recently, effective tissue clearing techniques including CLARITY and ACT-PRESTO have been reported that enables visualization of molecularly labeled structures within intact organs in three dimensions. The central principle of the methods is transformation of intact tissue into an optically transpicuous and macromolecule permeable state without loss of intrinsic structural integrity. The rapidly evolving protocols enable morphological analysis and molecular labeling of normal and pathological characteristics in large assembled biological systems with single-cell resolution. The deep tissue volume imaging will provide fundamental information about mutual interaction among adjacent structures such as connectivity of neural circuits; meso-connectome and clinically significant structural alterations according to pathologic mechanisms or treatment procedures.