• Title/Summary/Keyword: Biological filters

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우리나라 의용생체공학의 현황과 전망

  • 이충웅
    • Journal of Biomedical Engineering Research
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    • v.10 no.2
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    • pp.83-88
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    • 1989
  • This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively.

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Integration of a Large-Scale Genetic Analysis Workbench Increases the Accessibility of a High-Performance Pathway-Based Analysis Method

  • Lee, Sungyoung;Park, Taesung
    • Genomics & Informatics
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    • v.16 no.4
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    • pp.39.1-39.3
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    • 2018
  • The rapid increase in genetic dataset volume has demanded extensive adoption of biological knowledge to reduce the computational complexity, and the biological pathway is one well-known source of such knowledge. In this regard, we have introduced a novel statistical method that enables the pathway-based association study of large-scale genetic dataset-namely, PHARAOH. However, researcher-level application of the PHARAOH method has been limited by a lack of generally used file formats and the absence of various quality control options that are essential to practical analysis. In order to overcome these limitations, we introduce our integration of the PHARAOH method into our recently developed all-in-one workbench. The proposed new PHARAOH program not only supports various de facto standard genetic data formats but also provides many quality control measures and filters based on those measures. We expect that our updated PHARAOH provides advanced accessibility of the pathway-level analysis of large-scale genetic datasets to researchers.

Effects of Nitrifying Bacterial Communities with Different HRTs and Backwashing Periods in Modified BAF Process (Modified BAF 공정에서 HRT 및 역세주기가 질산화 미생물의 군집에 미치는 영향)

  • Jung, Chul-Soo;Park, Jeung-Jin;Ju, Dong-Jin;Kwon, Soo-Youn;Choi, Won-Seok;Byun, Im-Gyu;Park, Tae-Joo
    • Journal of Korean Society on Water Environment
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    • v.23 no.6
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    • pp.920-926
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    • 2007
  • The upflow Biobead$^{(R)}$ process, one of biological aerated filters (BAF), which was used commercially, invented for removal of organic materials and nitrification. This process was modified to enhance the ability of denitrification through the induction of pre-anoxic tank. In this research, we investigated the effects of hydraulic retention time (HRT) and backwashing period in aerobic tank. The characteristics of nitrifying bacteria, which are composed of ammonia-oxidizing bacteria (AOB) and nitrite-oxidizing bacteria (NOB), also investigated using fluorescence in situ hybridization (FISH). Even though the HRT was shortened, the efficiency of nitrification was not decreased when the organic loading rate and ammonium-nitrogen loading rate were $2.10kg/m^3/day$ and $0.25kg/m^3/day$, respectively. And then the distribution ratios of AOB and NOB showed the similar patterns. However, when the backwashing period was lengthened from 12 hours to 24 hours in aerobic 1 tank, the nitrification efficiency was decreased to 63.9% from 89.2%. The results of FISH explained that this decrease of nitrification efficiency was caused by the decrease of distribution ratio of AOB in aerobic 1 tank. The nitrification efficiencies of aerobic 1 and aerobic 2 tank were increased when the backwashing period was lengthened because of relative high distribution ratios of nitrifying bacteria.

Design of Small Acoustic Filter for ITE Type Noise Protector (ITE 타입의 소음 차폐기용 소형 음향 필터의 설계)

  • Lee, Yun-Jung;Kim, Pil-Un;Chang, Yong-Min;Lee, Sang-Heun;Cho, Jin-Ho;Kim, Myoung-Nam
    • Journal of Sensor Science and Technology
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    • v.13 no.6
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    • pp.479-487
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    • 2004
  • The prevention of noise induced hearing loss is very important, because there is no treatment for it. There are some kinds of devices for hearing protection, and those are effective in preventing a noise induced hearing loss. However, people often resist the use of hearing protection devices because it is difficult to have a conversation. Therefore, a hearing protection device is must effective not only in hearing protection but also in preserving communication ability. In this paper, we proposed a small acoustic filter for ITE type noise protector to solving the problem about the difficulties of conversation. That is applied a principle of acoustic filters that have been used for a muffler of automobiles, guns, and etc. To find out the sound transmission characteristic at the eardrum, we regarded an acoustic filter and external ear canal as a coupled system. So, we simulated the coupled system with OrCad, and experimented with a designed acoustic filter and a 2 cc coupler which has the same transmission characteristic as the external ear canal has. We confirmed that it is possible to adjustment acoustic transmission characteristics through simulation of electrical model for acoustic filter and external ear and experiments using designed small acoustic filters.

NO REDUCTION PROPERTY OF Pt-V2O5-WO3/TiO2 CATALYST SUPPORTED ON PRD-66 CERAMIC FILTER

  • Kim, Young-Ae;Choi, Joo-Hong;Bak, Young-Cheol
    • Environmental Engineering Research
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    • v.10 no.5
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    • pp.239-246
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    • 2005
  • The effect of Pt addition over $V_2O_5-WO_3/TiO_2$ catalyst supported on PRO-66 was investigated for NO reduction in order to develop the catalytic filter working at low temperature. Catalytic filters, $Pt-V_2O_5-WO_3/TiO_2/PRD$, were prepared by co-impregnation of Pt, V, and W precursors on $TiO_2$-coated ceramic filter named PRD (PRD-66). Titania was coated onto the pore surface of the ceramic filter using a vacuum aided-dip coating method. The Pt-loaded catalytic filter shifted the optimum working temperature from $260-320^{\circ}C$(for the catalytic filter without Pt addition) to $190-240^{\circ}C$, reducing 700 ppm NO to achieve the $N_x$ slip concentration($N_x\;=\;NO+N_2O+NO_2+NH_3$) less than 20 ppm at the face velocity of 2 cm/s. $Pt-V_2O_5-WO_3/TiO_2$ supported on PRD showed the similar catalytic activity for NO reduction with that supported on SiC filter as reported in a previous study, which implies the ceramic filter itself has no considerable interaction for the catalytic activity.

Design of Two Stage Amative Filters for Real time QRS Detection (실시간 ECG 분석을 위한 QRS 검출에 관한 연구 -2단 적응필터을 이용한-)

  • 이순혁;윤형로
    • Journal of Biomedical Engineering Research
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    • v.16 no.1
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    • pp.49-56
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    • 1995
  • This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter. The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively.

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A study on the development of an image processing technique for tracing the movement of heart valves in echocardiograms (I) (심초음파도내에서의 심장 판막 운동 추적을 위한 동영상 처리 기술에 대한 기초 연구 (I))

  • Yook, I.S.;Kim, J.I.;Choi, H.H.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.88-91
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    • 1997
  • One of the most significant feature of diagnostic ultrasonic instrument is to display information on the soft tissues in the body in real time. In this paper we carried out basic study on the digital moving image processing for tracing the movement of heart valves in echocardiograms. Digital moving image file was made from analog echocardiograms and it was remade as 256 gray-level images on each frame. The ROI(Region of interest) was placed on a heart valve region to process images efficiently. Images were processed by the use of image enhancement filters and morphology filters. The result shows that the processed images were more enhanced than original images. When a moving image is reconstructed by using these enhanced images, we can trace the movement of heart valves more easily. In this study we proposed the availability of the moving image reconstruction using enhancement images.

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Exposure Assessment for Airborne Biological Agents in Sawmills (제재업의 생물학적인자 노출실태 평가)

  • Park, Hae-Dong;Park, Hyun-Hee;Lee, In-Seop
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.20 no.4
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    • pp.274-281
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    • 2010
  • The objectives of this study are (a) to investigate the distribution patterns and exposure concentrations of biological agents in sawmill industries and (b) to compare sampling methods of biological agents. The representative processes of 5 sawmills were selected to measure total airborne bacteria, fungi, endotoxin as well as dust. Airborne bacteria and fungi were measured with one stage impactor, six stage impactor and gelatin filteration methods. Endotoxin was collected with polycarbonate filters and analysed by kinetic chromogenic Limulus Amebocyte Lysate method. Geometric mean levels of airborne bacteria, fungi, endotoxin and dust were 1,864 CFU/$m^3$, 2,252 CFU/$m^3$, 31.5 EU/$m^3$ and 2.4 mg/$m^3$. The ratios of indoor/outdoor concentrations were 3.7 for bacteria, 4.1 for fungi, 3.3 for endotoxin and 9.7 for dust. The respiratory fractions of bacteria were 68.0, 50.9, 49.2 and 45.1% in band-saw, table-saw, rip-saw process and outdoor air. The respiratory fractions of fungi were 78.7, 90.8, 87.5 and 84.8% in band-saw, table-saw, rip-saw process and outdoor air, respectively. There was no significant differences in bacterial concentrations among single stage, six stage impaction and filteration methods. But, fungal concentrations measured with filtration methods were significantly higher than those with impaction methods. Geometric mean levels of airborne bacteria and fungi were higher than the OSHA guideline values of 1,000 CFU/$m^3$. The respiratory fractions of fungi were above 75%. The concentrations of biological agents were significantly different among culture-based sampling methods. In the exposure assessments of biological agents, further studies are needed for the comparisons of diverse sampling methods and the investigations of environmental factors.

Magnetic Noise Reduction in MCG Using Spatial Filters (공간 필터를 이용한 심자도 신호에서의 자기잡음 제거)

  • Lee, Hana;Kim, Ki-Wang;Lee, Soo-Yeol;Cho, Min-Hyung;Heo, Young
    • Journal of Biomedical Engineering Research
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    • v.24 no.4
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    • pp.287-292
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    • 2003
  • Even though MCG has many advantages over ECG, MCG signa)s are easily corrupted by external magnetic noises Since multi-channel MCG signals are recorded simultaneously at many spatial positions, it is effective to apply spatial fitters as well as the conventional temporal filters to remove external magnetic noises. The spatial filters can be designed by utilizing the fact that the noise signals caused by external noise sources are more spatially correlated than the original MCG signals. In this paper, we introduce a spatial filtering method for the noise reduction in MCG based on the principal component analysis. Healthy volunteer study results obtained with a 61-channel MCG system are presented.

Role of Crossflow Module Media in Gas-liquid-solid Separation and Biomass Retention in Hybrid Anaerobic Filter (교차흐름식 모듈 충전 hybrid 혐기성여상의 기·액·고 분리능 및 슬러지보유능)

  • Chang, Duk;Chae, Hee-Wang;Bae, Hyung-Suk;Chung, In;Han, Sang-Bae;Hur, Joon-Moo;Hong, Ki-Ho
    • Journal of Korean Society of Water and Wastewater
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    • v.23 no.6
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    • pp.769-778
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    • 2009
  • Performances and internal behaviors of the upflow hybrid anaerobic filters treating a dairy wastewater were analyzed to identify the functions and roles of the modular crossflow media and sludge bed layer and to discover their interrelationship in the filter. The media could perform independent biological and physical separation role without buildup of sludge bed, while the role of sludge bed was dependent on the function of the media. The filter packed with the crossflow media did not necessarily require the formation of sludge bed when treating a dairy wastewater. Biological contribution of the media was controlled by that of biologically active sludge bed complementing mutually each other. The gas-liquid-solid separation capability of the media was indispensible to ensure the active biological role of sludge bed, since sludge bed buildup without the media had no independently effective biological function. It was believed that the filter in itself could also function as a selector for physical gas-liquid-solid separation resulting in selectively concentrating particles with superior settleability in sludge bed. The sludge bed in the filter played a key role in the physical solids capture from influent as well as biological organics removal.