• 생물정신의학
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• 제15권4호
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• pp.310-315
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• 2008

Objectives : The evaluation of disability after trauma in psychiatry is relatively subjective compared with other departments. A consensus among evaluators could improve reliability of evaluations. We compared disability rate of common psychiatric disorders without definite brain injury depending on their diagnosis from experienced evaluators in Korea. Methods : A written questionnaire was mailed to each evaluator and the reply was analyzed. The questions included disability rate ranges of postconcussional syndrome, PTSD and depression. Other questions related with admission for evaluation, expected duration of treatment, life expectancy and need of supporting person were also asked. Results : Range of disability rate were from $8.6{\pm}4.5%$ to $26.6{\pm}12.8%$ in postconcussional syndrome, from $10.4{\pm}6.8%$ to $36.4{\pm}13.8%$ in PTSD and from $10.0{\pm}4.6%$ to $30.6{\pm}10.3%$ in depressive disorder. There were lots of diversity in expected duration of treatment with psychiatric disability. Decline of life expectancy and need of supporting person were considered at least 50% of disability. Conclusion : There is much diversity in evaluation of psychiatric disabilities with disability rate and expected duration of treatments even among experienced evaluators. A common consensus among experts may increase reliability of psychiatric evaluations after trauma.

• 생약학회지
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• 제31권2호
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• pp.130-141
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• 2000

The dried roots of Rehmannia glutinosa (RG) have been used in the traditional medicine for treatment of diabetes, fever and dysuria, etc. In order to investigate the quality evaluation of the dried roots of RG, we conducted the physico-chemical and biological evaluation method. The amount of catalpol from commercial samples is very diverse about $0.00{\sim}3.89%$ by using HPLC method, because it is easily decomposed by processing of RG. So, we should try to identify the correlation with the contents of catalpol and biological activities of RG. We chose 3 samples which were a wide difference of catalpol contents between each sample (Sample-I; 3.4%, Sample-II; 2.8%, Sample-III; 0.05%). Sample-I and Sample-II were found to be more effective than Sample-III on the DPPH free radical scavenging effect and inhibitory effect on $H_2O_2-catalyzed$ lipid peroxidation in rat liver in vitro. And, Sample-I and Sample-II exhibited more significant effects than Sample-III on accelerating actions of the small and large intestinal transport, and diuretic action in mice. So, it is suggested that the quantitative determination of catalpol should be required for the tandardization of the dried roots of RG.

• 대한토목학회논문집
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• 제31권6B호
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• pp.565-575
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• 2011

본 연구는 다변수 접근방식인 서식지평가 정성지수(Qualitative Habitat Evaluation Index, QHEI)와 생물보전지수(Index of Biological Integrity, IBI)의 적용방법 도입과 어류 서식 및 피신처 확보용 인공구조물인 방틀둠벙의 정량적인 평가를 목적으로 하였다. 또한, 안동시 남후면 하아리에 소재한 한국건설기술연구원 수자원 환경실험센터의 실외 실험장을 활용하여 실규모로 생물 평가와 검증을 실시하였다. 본 평가기법의 적용을 위해 구성한 실험수로 및 방틀둠벙 시설은 국내 하천의 조건을 최대한 반영하여 조성하였으며, 흐름상태와 정체상태로 구분하여 유속 $0.0{\sim}1.5m\;s^{-1}$, 폭 1.0~3.0 m, 수심 0.05~0.70 m, 다양한 하상재료를 조성하여 2010년 5월~12월의 8개월간 모니터링 하였다. QHEI는 실험수로의 E~F지점이 평균 83.1로 가장 높게 나타났고, B~C지점에서 78.1로 가장 낮게 나타났다. 하지만 방틀둠벙은 시 공간적 구분 없이 98.9 이상의 값을 나타내어 전체 지점 중 가장 높은 양호상태(Good)의 서식처 조건을 유지하였다. IBI는 전반적으로 QHEI와 비슷한 패턴을 나타내었으나 겨울 갈수기에 양호상태(Good)인 44.2를 보여 32.8을 나타낸 실험수로와 비교되었다. 또한, 흐름과 정체상태 조건에서 방틀둠벙의 IBI 값은 실험수로보다 각각 5.7~11.4%, 18.7~34.8% 높은 평가 값을 나타내어, 유량이 적거나 흐름이 없는 갈수기에 어류 서식처 확보 가능성을 정량적으로 시사하였다. 종합적인 수생태계 건강성 평가에서 실험하천은 보통과 양호상태(Fair~Good) 범위를 나타낸 반면, 방틀둠벙은 대부분 양호상태(Good)를 보여 수생태계 건강성 확보에 적용 가능함을 도출하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권10호
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• pp.5263-5272
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• 2012

Background: Gastric cancer (GC) is one of the most common cancers in China. Adjuvant chemotherapy (AC) is a routine auxiliary treatment for GC recommended by the guidelines issued in 2011 by the Ministry of Health of the People's Republic of China, but the relevant credible consequences in China have been insufficient because of China's late start and ethical concerns. Methods: A series of databases, including Cochrane Library, MEDLINE, EMBASE, the Chinese database of the National Knowledge Infrastructure and the VIP database, were searched by 2 reviewers independently for studies investigating AC for GC through March 2012. The retrieved literature was screened according to the eligibility criteria. Results: A total of 35 randomized control trials (RCTs) were subjected to the final analysis, including 4,043 patients in treatment group and 3,884 in the control group, as well as 4 clinical-control trials (CCTs), which accessed the final analysis with 238 and 252 patients, respectively. AC reduced the risk of death as a protective treatment with statistical significance (HR=0.91, 95%CI: [0.85, 0.97], P=0.002), and it seemed more effective for Asian than non-Asian patients. The effects of AC were not influenced by the starting time (P>0.05). D2 lymphadenectomy-based chemotherapy was effective (HR=0.89, 95%CI: [0.80, 0.99], P=0.04). Oral S-1 40 mg/m2 after D2 lymphadenectomy might be a better choice for Asians with advanced GC and might result in a greater reduction of adverse events than in non-Asian patients. GRADE quality assessment determined that the strength of the evidence from foreign studies from Europe, the United States and Asian countries other than China was high, while it was moderate for Chinese studies. Conclusion: AC was effective or even curative in Chinese patients in general, although it is still necessary to optimize a targeted AC scheme for Chinese patients with GC.

• 환경생물
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• 제31권4호
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• pp.440-447
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• 2013

본 연구에서는 남한강 상류수계의 10개 지점에서 생물보전지수 (Index of Biological Integrity, IBI) 및 물리적 서식지 평가 지수 (Qualitative Habitat Evaluation Index, QHEI)를 이용하여 생태건강도 특성을 평가하였다. 생물보전지수 조사는 Karr (1981)가 제시한 12개 항목 중 11개 메트릭에 대하여 평가하였다. 생물보전지수 등급은 "양호상태"였고, 지점별 IBI 값의 범위는 33 (악화상태)~47 (양호상태)로 나타났다. 물리적 서식지측면에서는 Plafkin et al. (1989)에 의해 도입된 서식지 평가 지수(QHEI)의 12항목 중 9개 항목에 대해 평가를 실시했으며, QHEI 값의 범위는 75~109로 나타났으며, 전체 서식지 건강도 평균치는 부분 지지상태(Partially supporting)로 나타났다. 연구지점내의 하천 비교평가에 따르면, Gj 하천의 IBI 모델 값 및 QHEI 모델 값은 타 하천들 (Ig, Dn 하천)에 비해 양호한 상태로 평가되었다. 어류의 영양단계 종 성분분석에 따르면, 식충종, 잡식종 및 육식종은 61.9%, 19.0% 및 9.5%를 차지하는 것으로 나타났다. 어류의 내성도 길드분석에 따르면, 민감종 (76.1%)은 내성종 (4.7%)보다 우점하여 생태계가 건전한 것으로 평가되었다. 서식지 길드 분석에 따르면, 여울성 저서종(57.1%)은 수층종(28.5%)보다 우점하는 것으로 나타났다. 연구기간 동안, 외래종 및 질병에 걸리거나 비정상적인 증상을 나타내는 개체는 관측되지 않았다. 전체적으로 생태건강도 모델값(IBI) 및 서식지평가지수 모델값의 분석에 따르면 본 상류 하천지역은 생태학적으로 양호한 상태로 잘 유지되는 것으로 평가되었다.

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2000년도 추계심포지움 및 학술발표회:바이오모니터링 기법을 이용한 환경위해성 평가
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• pp.45-45
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• 2000

• Bulletin of the Korean Chemical Society
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• 제35권5호
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• pp.1537-1540
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• 2014

• Bulletin of the Korean Chemical Society
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• 제28권10호
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• pp.1824-1826
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• 2007

• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2005년도 추계학술대회 및 한일 식물생명공학 심포지엄
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• pp.345-345
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• 2005

• 한국동물학회:학술대회논문집
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• 한국동물학회 1994년도 한국생물과학협회 학술발표대회
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• pp.125.2-125
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• 1994

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