• Title/Summary/Keyword: Biological environmental assessment

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Application of Physiologically Based Pharmacokinetic Modeling with Biological Monitoring Data for Risk Assessment (생물학적 모니터링 데이터를 기초한 PBPK 모델의 활용)

  • Yang, Mi-Hi;Yang, Ji-Yeon;Yi, Bit-Na;Lee, Ho-Sun
    • Environmental Analysis Health and Toxicology
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    • v.22 no.1 s.56
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    • pp.1-8
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    • 2007
  • Biological monitoring, analyses of internal dose for exposure to toxicants, has been thought as one of the belt approaches for risk assessment. As the amount detected in human samples is generally very low, typically in the parts-per-bilion (ppb) or parts-per-trillion (ppt) range, analytic technologies such at HPLC, GC/MS, LC/MS, and LC/MS/MS have been continuously developed. In addition, route specific and sensitive exposure biomarkers have been developed for proper biological monitoring. PBPK modeling, particularly reverse dosimetry, has been emphasized as an useful method via interpretation of biological monitoring results for regulation of toxicants. Thus, this review is focused on the use of PBPK dosimetry models for toxicology research and risk assessment in Korea.

Development of Konan Saprobic Index using Benthic Macroinvertebrates and Its Application to Biological Stream Environment Assessment (저서성 대형무척추동물을 이용한 한국오수생물지수의 개발과 생물학적 하천환경평가 적용)

  • Won, Doo Hee;Jun, Yung Chul;Kwon, Sun Jik;Hwang, Soon Jin;Ahn, Kwang Guk;Lee, Jae Kwan
    • Journal of Korean Society on Water Environment
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    • v.22 no.5
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    • pp.768-783
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    • 2006
  • Biological stream environment assessment has been an essential trend of aquatic ecosystems among advanced countries, because the chemical water quality assessment has limitations that only represent temporal water environmental status. Benthic macroinvertebrates are the most popular bioindicator group useful to biological water quality assessment for a long time. In addition, a number of indices using benthic macroinvertebrates have recently been developed not only for water quality assessment but also for ecological health assessment. In this paper Korean Saprobic Index (KSI) based on Zelinka-Marvan's saprobic valency concept is developed by applying DIN 38410 in Germany. The KSI value was widely applicable to most Korean streams with the exception of sand-based large streams, for example main stream of Nakdong River. But as a result of non-linear regression analysis the correlation between KSI and $BOD_5$ concentration was high and KSI reflected water quality alteration for mid and long-term period. In spite of applicability of KSI, it should be supplemented and developed to make it strong by accumulating field data as well as to manage integrated water environment in general through continuous biomonitoring.

Development of Biological Criteria for Water Quality Assessment using Benthic Diatoms (부착돌말류를 이용한 생물학적 수질평가지표 개발)

  • Noh, Seongyou;Byeon, Myeongseop;Kim, Miah;Lee, Jaekwan
    • Journal of Korean Society on Water Environment
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    • v.25 no.6
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    • pp.879-885
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    • 2009
  • The present study was carried out to develop biological criteria for water quality assessment using benthic diatoms. Selecting of the indicator diatoms, three parameters were considered: broad distribution (180 taxa occurred over 3% at upper level), species abundance (158 taxa occurred over $1.5{\times}10^5cells/cm^2$), and sensitivity (184 taxa occurred more than once as 1st and 2nd dominant species). Overall, total 208 taxa were selected, including 38 varieties, 170 species, 34 genera, 9 families, 3 orders, and 1 phylum. The most dominant taxonomic group (family) was Naviculaceae (52%), followed by Diatomaceae (15%), Nitzschiaceae (12%) and Achnantaceae (11%). COD and TP were proposed as new water quality standards (draft) to improve the existing BOD standard and to manage and control efficiently non-biodegradable organic pollutants. With this regard, we used TP standard (draft) in developing biological water quality criteria for diatoms. TP standards (draft) proposed as Ia = 0.02 mg/L or less, Ib = 0.05 mg/L or less, II = 0.1 mg/L or less, III = 0.2 mg/L or less, IV = 0.4 mg/L or less, V = 0.6 mg/L or less and VI = above 0.6 mg/L. Biological assessment system (4 class system) was developed and proposed for diatom using modified Tropic Diatom Index (TDI). Biological assessment of TDI appear B grade (Good).

Investigation on the Main Exposure Sources of Nanomaterials for Nanohazards Assessment (나노위해성 관리를 위한 나노물질 주요 배출원 파악)

  • Kim, Young-Hun;Park, Jun-Su;Kim, He-Ro;Lee, Jeong-Jin;Bae, Eun-Joo;Lee, Su-Seung;Kwak, Byoung-Kyu;Choi, Kyung-Hee;Park, Kwang-Sik;Yi, Jong-Heop
    • Environmental Analysis Health and Toxicology
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    • v.23 no.4
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    • pp.257-265
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    • 2008
  • Nanotechnology is emerging as one of the key technologies of the 21 st century and is expected to enable one to broaden the applicability across a wide range of sectors that can benefit public and improve industrial competitiveness. Already, consumer products containing nanomaterials are available in markets including coatings, computers, clothing, cosmetics, sports equipment and medical devices. Recently, Institute of Occupational Medicine in UK reported an occupational hygiene review for nanoparticles in the viewpoint of nanotoxicity. They reported that the exposure control is very important issues in workplace for exposure assessment, but no proper methods are available to measure the extent of exposures to nanoparticles in the workplace. Therefore, for the estimation of exposure of nanomaterials, we have to approach the material-balance methodology, which similarly carried out in TRI (toxic release inventory) for hazardous chemicals. In order to use this methodology, the exposure source of nanomaterials should be determined firstly. Therefore, herein we investigated the main sources and processes for the exposure to nanomaterals by conducting the survey. The results could be used to define and assess nanohazard sources.

Methodology of Life Cycle Assessment(LCA) for Environmental Impact Assessment of Winter Rapeseed in Double-cropping System with Rice (겨울 유채의 환경성 평가를 위한 전과정평가(LCA) 방법론)

  • Nam, Jae-Jak;Ok, Yong-Sik;Choi, Bong-Su;Lim, Song-Tak;Jung, Yong-Su;Jang, Young-Seok;Yang, Jae-E.
    • Korean Journal of Environmental Agriculture
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    • v.27 no.2
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    • pp.205-210
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    • 2008
  • Life cycle assessment(LCA) is acknowledged as a valuable tool to quantify the environment impact of agricultural practice as well as final product(biodiesel) considering whole life cycle of the target product. As a preliminary research of LCA study for rapeseed(Brassica napus L.) biodiesel, the methodological issues which have to be regarded with high priority were dealt with. No life cycle inventory(LCI) based on local data are currently available for LCA of rapeseed cultivation, crushing, and conversion to rapeseed methyl ester(RME) in Korea. In this paper, the life cycle of rapeseed and methodological factors which have to be measured for building LCI of each process are provided and discussed, which are including seed, fertilizer, energy use in rapeseed cultivation environment; and crushing, RME conversion, and transportation in biodiesel production.

An Integrated Environmental Impact Assessment Model using FEMWASP and ArcView (FEMWASP 모형 및 ArcView를 결합한 통합적 환경영향평가 모형의 개발 및 적용)

  • Kim, Joon Hyun;Han, Young-Han;Choi, Yoon-Jung
    • Journal of Environmental Impact Assessment
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    • v.7 no.2
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    • pp.65-70
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    • 1998
  • An integrated EIA tool was developed to analyze present and future environmental quality status of Youngwol Basin using ArcView and FEMWASP. All the input data and computational results were prepared and graphically displayed on the basis of ArcView. FEMWASP and ArcView were integrated using the command "system.execute" in script of Avenue. Modeling items were inserted in the GUI of ArcView. The modeling result showed that the water quality of the proposed Yougwol Lake would be at the stage of eutrophication. The developed system can be applied to the water quality management of drinking water resources to set up the regulatory acts and project plan of governmental policy.

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Environmental Impact Assessments along with Construction of Residential and Commercial Complex (주거단지 건설이 하천에 미치는 생태영향평가)

  • An, Kwang-Guk;Han, Jeong-Ho;Lee, Jae Hoon
    • Journal of Environmental Impact Assessment
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    • v.21 no.5
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    • pp.631-648
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    • 2012
  • The integrative ecological approaches of chemical assessments, physical habitat modelling, and multi-metric biological health modelling were applied to Gwanpyeong Stream within Gap-Stream watersheds to evaluate environmental impacts on the constructions of residential and commercial complex. For the analysis, the surveys conducted from 45 sites of reference streams within the Gap-Stream watershed and 3 regular sites during 2009 - 2010. Physical habitat health, based on the habitat model of Qualitative Habitat Evaluation Index(QHEI) declined from the headwaters(good - fair condition) to the downstream(poor condition). Chemical water quality, based turbidity and electric conductivity(EC), was degraded toward to the downstream, and especially showed abrupt increases, compared to the values of control streams(CS). Also, concentrations of chlorophyll-a in the downstreams were greater compared to the control stream(CS), indicating an eutrophication. Biological health conditions, based on the Index of Biological Integrity(IBI) using fish assemblages, averaged 19.3 which is judged as a fair condition by the biological criteria of the Ministry of Environment, Korea. The comparisons of model metric values in sensitive species and riffle-benthic species on the Maximum Species Richness Line(MSRL) of 45 reference streams indicated a massive disturbances in all sampling locations. Also, tolerance guild and trophic guild analyses suggest that dominances of tolerant species and omnivores were evident, indicating a biological degradation by habitat disturbances and organic matter pollutions. There was no distinct longitudinal variations of IBI model values from the headwater to the downstream in spite of slight chemical and habitat health gradients among the sampling sites. Overall, integrative ecological health(IEH) scores, based on the chemical, physical, and biological parameters, were low compared to the 45 reference streams due to physical and chemical disturbances of massive constructions of the residential and commercial complex. This stream, thus showed a tendency of typical urban streams which are disturbed in the chemical water quality, habitat structures, and biological integrity. Effective stream management plans and restoration strategies are required in this urban stream for improving integrative stream health.

The Development of Exposure Assessment Tools for Risk Assessment of Volatile Organic Compounds (VOCs의 위해성 평가를 위한 노출분석 방법 연구)

  • Jo, Seong-Joon;Shin, Dong-Chun;Chung, Yong;Lee, Duck-Hee;Breysse, Patrick N.
    • Environmental Analysis Health and Toxicology
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    • v.17 no.2
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    • pp.147-160
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    • 2002
  • Volatile organic compounds (VOCs) are an important public health issue in Korea and many important questions remain to be addressed with respect to assessing exposure to these compounds. Because they are ubiquitous and highly volatile, special techniques must be applied in their analytic determination Valid Personal exposure assessment methods are needed to evaluate exposure frequency, duration and intensity, as well as their relationship to personal exposure characteristics. Biological monitoring is also important since it may contribute significantly in risk assessment by allowing the estimation of effective absorbed doses. This study was on ducted to establish the environmental measurement, personal dosimetry and biological monitoring methods for VOCs. These methods are needed to compare blood, urinary and exhalation breath VOC levels and to provide tools for risk assessment of VOC exposure. Passive monitors (badge type) and a active samplers (trap) for the VOCs collection were used for air sampling. Methods development included determining the minimum detectable amounts of VOCs in each media, as well as evaluating collection methods and developing analytical procedures. Method reliability was assessed by determining breakthrough volumes and comparing results between laboratories and with other methods. A total capacity of trap used in this study was 60ι. Although variable by compound, the average breakthrough was 20%. Also, there was no loss of compounds in trap even if keep for 45 day in -7$0^{\circ}C$. The recovery of active and passive methods was 69% ~ 126% and method detection limit was 0.24 $\mu\textrm{g}$/trap and 0.07 $\mu\textrm{g}$/badge. There was no statistical difference (P > 0.05) between active and passive methods.

Life Cycle Assessment on the End-of-Life Vehicle Treatment System in Korea (국내 폐자동차 처리시스템에 대한 전과정평가)

  • Hong, Seok-Jin;Jeong, Kee-Mo;Hong, John-Hee;Yun, Ju-Ho;Hur, Tak
    • Transactions of the Korean Society of Automotive Engineers
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    • v.13 no.6
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    • pp.105-112
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    • 2005
  • This study aims at evaluating the environmental impacts stemmed from the End-of-Life Vehicle(ELV) treatment systems in Korea, using Life Cycle Assessment(LCA) method. In this study, both environmental burden from the ELV dismantling process & recycling processes and environmental benefit which were derived from the avoided environmental impacts by substituting recycled materials for virgin materials were considered. First of all, the key issues which were defined as the environmental aspects that account for more than $1\%$ out of the total environmental impacts were identified from the Life Cycle Impact Assessment(LCIA). $CO_2$, crude oil, natural gas, coal, etc. were found out to be the key issue parameters. From the LCI Analysis and LCIA studies, it was shown that the significant environmental aspects were related with the recycling process of ferro scrap, the shredding process of compressed car bodies and the dismantling process of end-of-life engines. In particular, the recycling process of ferro scrap has the most significant effects on the environmental impacts of the ELV treatment systems. Based on these results, it is recommended to improve the recycling process of ferro scrap in order to make the ELV treatment systems more environmentally sound.