• Title/Summary/Keyword: Biological assessment

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Ultrasound Attenuation in the Assessment of Bone Mineral Density and Elastic Modulus of Human Trabecular Bone

  • Han, S.M.;Kim, M.S.
    • Journal of Biomedical Engineering Research
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    • v.19 no.2
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    • pp.171-176
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    • 1998
  • The objective of this study was to re-evaluate ultrasound attenuation as an indicator of bone properties. Ultrasound attenuation(BUA), were measured in the three orthogonal directions of trabecular bone cubes, Measurements of bone mineral density(BMD) were made using quantitative computed tomography and apparent density by weighing bone specimens and measuring their volume. Ultrasonic modulus was calculated from the standard equation with apparent density and ultrasound velocity. Ultrasound attenuation at a frequency of 0.5 MHz and BUA were correlated with BMD and ultrasonic modulus in the anterior/posterior, medial/lateral, and superior/inferior directions. Analysis of correlations demonstrated that attenuation at 0.5 MHz was superior to BUA in describing both BMD and elastic modulus of trabecular bone. This result may be used to improve current ultrasound diagnostic techniques for assessing bone status.

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Self-Management Knowledge, Self-Management, Physiological Indexes, and Symptoms Experience according to Dialysis Methods (투석방법에 따른 자가관리 지식, 자가관리, 생리적 지표와 증상경험)

  • Moon, Jeong Hwa;Shin, Yun Hee
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.25 no.3
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    • pp.220-230
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    • 2018
  • Purpose: This study was a cross-sectional study comparing differences in self-management knowledge, self-management, physiologic indexes, and symptoms experience for two methods of dialysis. Methods: Participants were 90 patients on hemodialysis and 91 on peritoneal dialysis at A hospital. Results: There was no significant difference between the two groups for knowledge of self-management. A comparison of the categories in the evaluation of self-management showed that patients in the peritoneal dialysis group took better care of their dialysis access route (F=17.61, p<.001) and dialysis schedule (F=4.30, p=.040). The physiologic indexes between the two dialysis groups showed that hemoglobin levels were higher in the hemodialysis group (F=5.28, p=.023). The product of serum calcium and phosphate was higher in the peritoneal dialysis group (F=11.42, p=.001). Serum sodium level was also higher in the peritoneal dialysis group (t=5.36, p<.001) while serum albumin level (t=-3.36, p=.001) and mean arterial blood pressure (t=-2.50, p=.013) were higher in hemodialysis patients. There were no significant differences in the proportion of uncomfortable experiences between the two groups. Conclusion: Medical personnel should consider differences in self-management knowledge/self-management, physiologic indexes, and symptoms experience for hemodialysis and peritoneal dialysis populations, and should provide adequate education accordingly and promote behavioral change to improve physiologic indexes and reduce symptoms.

KOMPSAT Data Processing System: An Overview and Preliminary Acceptance Test Results

  • Kim, Yong-Seung;Kim, Youn-Soo;Lim, Hyo-Suk;Lee, Dong-Han;Kang, Chi-Ho
    • Korean Journal of Remote Sensing
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    • v.15 no.4
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    • pp.357-365
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    • 1999
  • The optical sensors of Electro-Optical Camera (EOC) and Ocean Scanning Multi-spectral Imager (OSMI) aboard the KOrea Multi-Purpose SATellite (KOMPSAT) will be placed in a sun synchronous orbit in late 1999. The EOC and OSMI sensors are expected to produce the land mapping imagery of Korean territory and the ocean color imagery of world oceans, respectively. Utilization of the EOC and OSMI data would encompass the various fields of science and technology such as land mapping, land use and development, flood monitoring, biological oceanography, fishery, and environmental monitoring. Readiness of data support for user community is thus essential to the success of the KOMPSAT program. As a part of testing such readiness prior to the KOMPSAT launch, we have performed the preliminary acceptance test for the KOMPSAT data processing system using the simulated EOC and OSMI data sets. The purpose of this paper is to demonstrate the readiness of the KOMPSAT data processing system, and to help data users understand how the KOMPSAT EOC and OSMI data are processed, archived, and provided. Test results demonstrate that all requirements described in the data processing specification have been met, and that the image integrity is maintained for all products. It is however noted that since the product accuracy is limited by the simulated sensor data, any quantitative assessment of image products can not be made until actual KOMPSAT images will be acquired.

Potential Evaluation and Health Fostering Intrinsic Traits of Novel Probiotic Strain Enterococcus durans F3 Isolated from the Gut of Fresh Water Fish Catla catla

  • Alshammari, Eyad;Patel, Mitesh;Sachidanandan, Manojkumar;Kumar, Prashant;Adnan, Mohd
    • Food Science of Animal Resources
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    • v.39 no.5
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    • pp.844-861
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    • 2019
  • Over the last few years, marine environment was found to be a source of surplus natural products and microorganisms with new bioactive secondary metabolites of interest which can divulge nutritional and biological impact on the host. This study aims to assess the possible, inherent and functional probiotic properties of a novel probiotic strain Enterococcus durans F3 (E. durans F3) isolated from the gut of fresh water fish Catla catla. Parameters for evaluating and describing the probiotics described in FAD/WHO guidelines were followed. E. durans F3 demonstrated affirmative results including simulated bile, acid and gastric juice tolerance with exhibited significant bactericidal effect against pathogens Staphylococcus aureus, Salmonella Typhi, Escherichia coli and Pseudomonas aeruginosa. This can be due to the enterocin produced by E. durans F3 strain, which was resolute by sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) gel with amplification of the anticipated fragment of a structural gene; enterocin A, followed by antibiotic susceptibility assessment. Effective antioxidant potentiality against ${\alpha}$-diphenyl-${\alpha}$-picrylhydrazyl free radicals including lipase, bile salt hydrolase activity with auto-aggregation and cell surface hydrophobicity was similarly observed. Results are proving the potentiality of E. durans F3, which can also be used as probiotic starter culture in dairy industries for manufacturing new products that imparts health benefits to the host. Finding the potent and novel probiotic strains will also satisfy the current developing market demand for probiotics.

Spatially Distributed Model for Soil Loss Vulnerability Assessment in Mekong River Basin

  • Thuy, H.T.;Lee, Giha;Lee, Daeeop;Sophal, Try
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.188-188
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    • 2016
  • The Mekong which is one of the world's most significant rivers plays an extremely important role to South East Asia. Lying across six riparian countries including China, Myanmar, Thailand, Laos, Cambodia and Vietnam and being a greatly biological and ecological diversity of fishes, the river supports a huge population who living along Mekong Basin River. Therefore, much attention has been focused on the giant Mekong Basin River, particularly, the soil erosion and sedimentation problems which rise critical impacts on irrigation, agriculture, navigation, fisheries and aquatic ecosystem. In fact, there have been many methods to calculate these problems; however, in the case of Mekong, the available data have significant limitations because of large area (about 795 00 km2) and a failure by management agencies to analyze and publish of developing countries in Mekong Basin River. As a result, the Universal Soil Loss Equation (USLE) model in a GIS (Geographic Information System) framework was applied in this study. The USLE factors contain the rainfall erosivity, soil erodibility, slope length, steepness, crop management and conservation practices which are represented by raster layers in GIS environment. In the final step, these factors were multiplied together to estimate the soil erosion rate in the study area by using spatial analyst tool in the ArcGIS 10.2 software. The spatial distribution of soil loss result will be used to support river basin management to find the subtainable management practices by showing the position and amount of soil erosion and sediment load in the dangerous areas during the selected 56- year period from 1952 to 2007.

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Economic Valuation of the Creation Project of Snow Crab Spawning and Habitat Ground (대게 산란·서식장 조성사업의 경제성 평가: 울진·영덕군의 사례를 중심으로)

  • Kang, Seok-Kyu
    • The Journal of Fisheries Business Administration
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    • v.51 no.4
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    • pp.19-45
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    • 2020
  • This study is to evaluate economic effect of the creation project of snow crab, Chionoecetes opilio, spawning and habitat ground in Uljin and Youngdeok county. The main results of this study are summarized as follows: first, 14,400 million won was invested in the creation project cost of Chionoecetes opilio spawning and habitat ground of Uljin and Youngdeok County from 2015 to 2020. Second, the creation project of Chionoecetes opilio spawning and habitat ground directly provides fishing benefits, festival benefits, research and development benefits and employment benefits. Third, on the basis of above benefits, the creation project of Chionoecetes opilio spawning and habitat ground has net present value of 29,900.53 million won, internal rate of return 16.9%, and benefit-cost of 2.91 under a 4.5% social discount rate. Also, the creation project creates 195 jobs. This indicates that the creation project of Chionoecetes opilio spawning and habitat ground not only contributes to the increase in the income of coastal fishery and fishing villages but also to the job making. The result of this study provides useful information to policy makers or project managers as it shows that the project to create spawning and habitat ground should be carried out in consideration of the resource and biological characteristics of individual fish and that economic assessment logic should also be developed based on this. Also, it proves that the project to create a snow crab spawning and habitat ground is a national and local infrastructure project that increases the actual fishing income in the region. At the same time, it maintains the reproducibility function of most fish species, along with enhancing the people's benefits such as fishing village tourism and marine product consumption. Moreover, it provides useful information on budgeting for the continuous development of snow crab spawning and habitat ground in the mid to long-term.

Molecular biological analysis of Bt-transgenic (Bt-9) rice and its effect on Daphnia magna feeding

  • Oh, Sung-Dug;Yun, Doh-Won;Chang, Ancheol;Lee, Yu-jin;Lim, Myung-Ho
    • Korean Journal of Agricultural Science
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    • v.46 no.1
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    • pp.113-124
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    • 2019
  • Insect-resistant transgenic (Bt-9) rice was generated by inserting mCry1Ac1, a modified gene from the soil bacterium Bacillus thuringiensis, into the genome of a conventional variety of rice (Ilmi). With regard to potential problems such as safety, an evaluation of non-target organisms is necessary as an essential element of an environmental risk assessment of genetically modified (GM) crops. We studied the effects of the Bt-9 rice on the survival of cantor Daphnia magna, a commonly used model organism in ecotoxicological studies. D. magna fed on the Bt-transgenic rice (Bt-9) and its near non-GM counterparts (Ilmi) grown in the same environment (a 100% ground rice suspension). The Bt-9 rice was confirmed to have the inserted T-DNA and protein expression evident by the PCR and ELISA analyses. The feeding study showed a similar cumulative immobility and abnormal response of the Daphnia magna between the Bt-9 rice and Ilmi. Additionally, the 48 h-EC50 values of the Bt-9 and Ilmi rice were 4,400 mg/L (95% confidence limits: 3861.01 - 5015.01 mg/L) and 5,564 mg/L (95% confidence limits: 4780.03 - 6476.93 mg/L), respectively. The rice NOEC (No observed effect concentration) value for D. magna was suggested to be 1,620 mg/L. We conclude that the tested Bt-9 and Ilmi have a similar cumulative immobility for D. magna, a widely used model organism, and the growth of Bt-9 did not affect non-target insects.

Study on the Effects of Phenyldiazenylanilines on the Activation of Arylhydrocarbon Receptor (Phenyldiazenylaniline 유도체가 방향족탄화수소 수용체의 활성에 미치는 영향)

  • Lee, Hyosung
    • Journal of the Korea Convergence Society
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    • v.10 no.1
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    • pp.285-290
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    • 2019
  • AHR regulates the expression of xenobiotics metabolizing enzymes (XMEs) as a transcription fact upon binding of ligands that are mainly aryl hydrocarbons. The role of AHR in human physiology has been intensively investigated for the past decades, however our understanding on AHR yet to be elucidated largely due to the lack of proper chemical agents. It has been demonstrated that AHR correlates to pathogenesis for some diseases in recent studies suggesting that the study on the AHR may provide a valid therapeutic target. Classical antagonists in current use are reported to be partially agonistic whereas a pure antagonist is yet to be found. In this study, phenyldiazenylaniline has been designed based on the structure of two known AHR antagonist, Resveratrol and CH223191. The derivatives of phenyldiazenylaniline have been prepared and subjected to assessment as an AHR antagonist in order to optimize the AHR antagonistic activity of the designed structure by means of convergence study of organic synthesis and molecular biology.

Assessment of Effective Dose for General Radiography of Adults Based on Diagnostic Reference Level(DRL) by Using PCXMC Program (진단참고준위(DRL)를 기준으로 PCXMC 프로그램을 이용한 성인의 일반촬영 부위별 유효선량 평가)

  • Jeong, Hee-Cheol;Lee, SamYol
    • Journal of the Korean Society of Radiology
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    • v.12 no.7
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    • pp.807-812
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    • 2018
  • In this study, we investigated the conditions used in setting the recommendation level of general radiography diagnostic reference and tried to evaluate the effective dose and biological evaluation using PCXMC v2.0 program. As a result based on the effective dose of male in ICRP 60, the highest Pelvis AP was 0.794 mSv. The lowest Chest PA was 0.050 mSv. In the case of ICRP 103, the highest T-Spine AP was 0.906 mSv The lowest Chest PA was 0.052 mSv. For 40 years old male and female adults, effective doses of general radiography were evaluated and even if the medical exposures are not subject to the limit of dose, efforts should be made to reduce the medical exposures of the people by keeping the dose below the recommended amount in order to minimize the probable effect of radiation hazard.

Anti-photoaging Effects of Fermented Soybean (Bio-Peptone®) (대두 발효물(Bio-Peptone®)의 광노화 억제 효과)

  • Kim, Eun Ju;Shim, Myeong Kuk;Jeong, A Ram;Kim, Ae Jung
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.45 no.1
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    • pp.27-36
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    • 2019
  • Soybean (Glycine max), as one of the foods with high plant proteins, contains a large amount of bioactive compounds and known to be effective in cardiovascular disease and obesity as well as in improving skin condition. The purpose of this study was to investigate the anti-photoaging effects of soybean fermented with Lactobacillus Rhamnosus ($Bio-Peptone^{(R)}$) by assessment of cytotoxicity against UVB, collagen synthesis after UVB-irradiation, tyrosinase activity, and melanin synthesis. Results showed that $Bio-Peptone^{(R)}$ protected skin fibroblasts against UVB-induced cytotoxicity and increased type I collagen synthesis. Furthermore, $Bio-Peptone^{(R)}$ significantly inhibited tyrosinase activity and reduced melanin contents. This study suggests that $Bio-Peptone^{(R)}$ has protective effects against UVB-induced skin damage. Thus, it is concluded that $Bio-Peptone^{(R)}$ is able to prevent skin damage against UVB and thus acts as anti-photoaging materials by protecting skin forming wrinkles and skin pigments.