• 제목/요약/키워드: Biological Synthesis

검색결과 1,240건 처리시간 0.025초

Carbamate 화합물의 합성 및 보건학적 연구 (Synthesis and Biological Activities of Carbamate Derivative)

  • 민경진
    • 한국환경보건학회지
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    • 제17권1호
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    • pp.104-109
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    • 1991
  • Carbamates are generally used as insecticide, thus 8-hydroxy-5-chloroquinolinyl-N-ethylcarbamate was newly synthesized. Its physical properties were determined and chemical structure was identified by means of IR, nmr in addition to elemental analysis. The effect of the compound on rat's ileum, and antibacterial activity against Staphylococcus aureus, Salmonella typhi, E. coli, and Pseudomonas aeruginosa were examined. It was observed that the dosage over 100 $\mu$g/ml of the compound relaxed rat's ileum and the same dosage of the compound inhibited growth of the above strains of bacteria.

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Synthesis and Biological Activites of Wogonin

  • Jinhyun-Jeong;Kim, Dongmyung-
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 2001년도 추계학술대회 및 정기총회
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    • pp.80-80
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    • 2001
  • The roots of Scutellaria baicalensis Georgi have been used in the chinese medicine for the treatment of inflammation, fever and headache. Recent studies had shown that baicalin and baicalein showed a detoxifying effect and could inhibit peripheral capillary permeability, and Wogonin was found to inhibit the proliferation of tumor cells. Wogonin has been synthesized as shown in schem. Compound 2 was prepared from 2,6-dimethoxy-1,4-benzoquinone(1) followed by acylation to give compound 3. The base treatment of 3 gave cyclized product which was carried by deprotection of methyl group chemoselectively. Overall step included relatively simple ten steps.

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Synthesis and Antibacterial Activities of Triphenyltin Cephalosporins

  • Park, Sang-Woo;Kim, You-Seung;Chung, Young-Keun
    • Archives of Pharmacal Research
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    • 제12권3호
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    • pp.231-232
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    • 1989
  • Although it has been known that organometallic $\beta$-lactam compounds improve the resistance to $\beta$-lactamases as well as their pharmacological activities, only a few results on organometallic $\beta$-lactam antibiotics were reported. In the course of our extensive study on the development of new cephalosporins, we were interested in organotin compounds since they show some biological activities.

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Gelatin에 Butyl Methacrylate 그라프트 공중합체의 합성과 생체적합성 (Synthesis and Biocompatibility of Graft Copolymer of Butyl Methacrylate onto Gelatin)

  • 김상기;김공수
    • 대한의용생체공학회:의공학회지
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    • 제11권1호
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    • pp.47-56
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    • 1990
  • The grafting of butyl methacrylate onto gelatin was investigated by potassium persulfate(KPS) redox system in aqueous solution. The optimum conditions of grafting were observed, and the physical property and the biocolnpatibility of graft copolymer membrane were examined. The gas permeability and the biodegradation by bacteria were decreased with the grafting percentage increased, and tensile strength increased with the grafting percentage increased.

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