• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 추계학술대회
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• pp.125-128
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• 1996

A new type of motor-driven total artificial heart system with a moving-actuator mechanism has been developed. The prototype system consists of a brushless do motor inside of actuator, two polyurethane sacs, and peripheral devices with internal controller. In this research work, the moving-actuator type electromechanical total artificial heart was redesigned for a good anatomical fitting. For total implantation we are developing the internal controller with high reliability and stability, and automatic control algorithm in response to the physiological requirements of animal. Contents and scope of the research work on ";Development of a totally implantable artificial heart of pre-clinical stage"; is summerized below 1) Animal experiment using sheep(55-60kg) 2) Development of implantable controller 3) Automatic control algorithm 4) Improvement of biocompatibility 5) Redesign of Actuator/blood pump.

• 한국산학기술학회논문지
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• 제20권1호
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• pp.464-469
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• 2019

본 논문에서는 화생방 방호시설에 사용되는 가스 차단밸브를 비롯한 각종 밸브 및 출입통제 챔버를 제어할 수 있는 원격 감시패널과 제어시스템을 개발하였다. 원격 감시패널은 화생방 통제실에 설치되는 메인 패널과 청정 기계실에 설치되는 보조 패널로 구성하였으며, 그 크기를 순수 제어용과 CCTV를 포함한 제어용으로 구분하여 개발하였다. 본 시스템은 방폭문 및 가스 차단문이 전시 및 평시에 발생할 수 있는 상황별 상태에 따라 원격 감시 및 제어가 가능하며, 평시모드와 전시모드로 구분하여 각 모드 작동시 추가적인 활성창을 통하여 제어 정보를 표시한다. 특히, 화생방 방호시설 내부의 각종 밸브 및 센서 그리고 각종 여과기의 동작상태를 주기적으로 센싱하여 각각의 기구 및 기기들의 정상동작 여부를 파악하며, 수리 및 교체가 필요할 경우 이를 원격으로 상황 근무자에게 경보함으로써 위급상황에서 각각의 기기들의 동작이상으로 인한 피해를 미연에 방지한다. 이를 통하여 화생방 상황 발생시 차단밸브 및 양압밸브의 상태에 따른 송풍기, 급기 및 배기 댐퍼의 작동, 비상 발전기 및 냉각수 펌프 등의 제어가 가능하여 재래식 무기 및 핵폭발에 의한 폭풍압의 급격한 유입으로 인한 피해를 예방할 수 있다.

• 설비공학논문집
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• 제14권12호
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• pp.1102-1139
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• 2002

A review on the papers published in the Korean Journal of Air-Conditioning and Refrigerating Engineering in 2000 and 2001 has been done. Focus has been put on current status of research in the aspect of heating, cooling, ventilation, sanitation and building environment. The conclusions are as follows. (1) Most of fundamental studies on fluid flow were related with heat transportation of facilities. Drop formation and rivulet flow on solid surfaces were interesting topics related with condensation augmentation. Research on micro environment considering flow, heat, humidity was also interesting for comfortable living environment. It can be extended considering biological aspects. Development of fans and blowers of high performance and low noise were continuing topics. Well developed CFD technologies were widely applied for developing facilities and their systems. (2) Most of papers related with heat transfer analysis and heat exchanger shows dealt with convection, evaporation, and channel flow for the design application of heat exchanger. The numerical heat transfer simulation studies have been peformed and reported to show heat transfer characteristics. Experimental as well as numerical studies on heat exchanger were reported, while not many papers are available for the system analysis including heat exchanger. (3) A review of the recent studies on heat pump system shows that performance analysis and control of heat pump have been peformed by various simulations and experiments. The research papers on multi-type heat pump system increased significantly. The studies on heat pipe have been examined experimently for change of working characteristics and strut lure. Research on the phase change has been carried out steadily and operation strategies of encapsulated ice storage tank are reported experimentally in several papers. (4) A review of recent studies on refrigeration/air conditioning system have focused on the system performance and efficiency for new alternative refrigerants. Evaporation and condensation heat transfer characteristics are investigated for tube shapes and new alternative refrigerants. Studies on components of refrigeration/air conditioning system are carried to examine efficiency for various compressors and performance of new expansion devices. In addition to thermophysical properties of refrigerant mixtures, studies on new refrigerants are also carried out, however research works on two-phase flow seemed to be insufficient. (5) A review of the recent studies on absorption cooling system indicates that heat and mass transfer phenomena have been investigated to improve absorber performance. Various experimental data have been presented and several simulation models have been proposed. A review of the recent studies on duct and ventilation shows that ventilation indices have been proposed to quantify the ventilation performance in buildings and tunnels. Main efforts have been focused on the applications of ventilation effectiveness in practice, either numerically using computational fluid dynamics or experimentally using tracer gas techniques. (6) Based on a review of recent studies on indoor thermal environment and building service systems, research issues have mainly focused on many innovative ideas such as underfloor air-conditioning system, personal environmental modules, radiant floor cooling and etc. Also, the new approaches for minimizing energy consumption as well as improving indoor environmental conditions through predictive control of HVAC systems, various activities of building energy management and cost-benefit analysis for economic evaluation were highlighted.

• 설비공학논문집
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• 제16권12호
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• pp.1234-1268
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• 2004

A review on the papers published in the Korean Journal of Air-Conditioning and Refrigerating Engineering in 2002 and 2003 has been carried out. Focus has been put on current status of research in the aspect of heating, cooling, air-conditioning, ventilation, sanitation and building environment/design. The conclusions are as follows. (1) Most of fundamental studies on fluid flow were related with heat transportation in diverse facilities. Drop formation and rivulet flow on solid surfaces were interesting topics related with condensation augmentation. Research on micro environment considering flow, heat transfer, humidity was also interesting to promote comfortable living environment. It can be extended considering biological aspects. Development of fans and blowers of high performance and low noise were continuing research topics. Well developed CFD technologies were widely applied for analysis and design of various facilities and their systems. (2) Heat transfer characteristics of enhanced finned tube heat exchangers and heat sinks were extensively investigated. Experimental studies on the boiling heat transfer, vortex generators, fluidized bed heat exchangers, and frosting and defrosting characteristics were also conducted. In addition, the numerical simulations on various heat exchangers were performed and reported to show heat transfer characteristics and performance of the heat exchanger. (3) A review of the recent studies shows that the performance analysis of heat pump have been made by various simulations and experiments. Progresses have been made specifically on the multi-type heat pump systems and other heat pump systems in which exhaust energy is utilized. The performance characteristics of heat pipe have been studied numerically and experimentally, which proves the validity of the developed simulation programs. The effect of various factors on the heat pipe performance has also been examined. Studies of the ice storage system have been focused on the operational characteristics of the system and on the basics of thermal storage materials. Researches into the phase change have been carried out steadily. Several papers deal with the cycle analysis of a few thermodynamic systems which are very useful in the field of air-conditioning and refrigeration. (4) Recent studies on refrigeration and air-conditioning systems have focused on the system performance and efficiency enhancement when new alternative refrigerants are applied. Heat transfer characteristics during evaporation and condensation are investigated for several tube shapes and new alternative refrigerants including natural refrigerants. Efficiency of various compressors and performance of new expansion devices are also dealt with for better design of refrigeration/air conditioning system. In addition to the studies related with thermophysical properties of refrigerant mixtures, studies on new refrigerants are also carried out. It should be noted that the researches on two-phase flow are constantly carried out. (5) A review of the recent studies on absorption refrigeration system indicates that heat and mass transfer enhancement is the key factor in improving the system performance. Various experiments have been carried out and diverse simulation models have been presented. Study on the small scale absorption refrigeration system draws a new attention. Cooling tower was also the research object in the respect of enhancement its efficiency, and performance analysis and optimization was carried out. (6) Based on a review of recent studies on indoor thermal environment and building service systems, it is noticed that research issues have mainly focused on several innovative systems such as personal environmental modules, air-barrier type perimeterless system with UFAC, radiant floor cooling system, etc. New approaches are highlighted for improving indoor environmental conditions and minimizing energy consumption, various activities of building energy management and cost-benefit analysis for economic evaluation.

• 대한의용생체공학회:의공학회지
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• 제28권4호
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• pp.569-576
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• 2007

Ventricular Assist Device(VAD) has switched its goal from a short-tenn use for bridge-to-transplantation to a long-tenn use for destination therapy, With this goal, the importance of long-tenn reliability gets more interests and importances, H-VAD is an portable extracorporeal biventricular assist device, and adopts an electro-pneumatic driving mechanism. The pneumatic pressure to pump out blood is generated with compression of bellows, and is transmitted in a closed pneumatic circuit through a pneumatic line. The existing pneumatic VAD adopts a air compressor which can generate stable pressures but has defects such as a noise and a size problem. Thus, it is not suitable for being used as a portable device, These problems are covered with adopting a closed pneumatic circuit mechanism with a bellows which has a small size and small noise generation, but it has defects that improper pneumatic setting causes a failure of adequate flow generation. In this study, the pneumatic pressure regulation system is developed to cover these defects of a bellows-type pneumatic VAD. The optimal pneumatic pressure conditions according to various afterload conditions for an optimal flow rate were investigated and the afterload estimation algorithm was developed, The final pneumatic regulation system estimates a current afterload and regulate the pneumatic pressure to the optimal point at a given afterload condition. The afterload estimation algorithm showed a sufficient performance that the standard deviation of error is 8.8 mmHg, The pneumatic pressure regulation system showed a sufficient performance that the flow rate was stably governed to various afterload conditions. In a further study, if a additional sensor such as ultrasonic sensor is developed to monitor the direct movement of diaphragm in a blood pump part, the reliability would be greatly increased. Moreover, if the afterload estimation algorithm gets more accuracy, it would be also helpful to monitor the hemodynamic condition of patients.

• 대한한방내과학회지
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• 제31권1호
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• pp.128-141
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• 2010

Purpose : The object of this study was to observe the suppressive effects of Yijintang-gamibang (YJGMB), Yijintang with Atractylodis Rhizoma, Massa Medicata Fermentata, Hordei Fructus Germiniatus, and Coptidis Rhizoma. YJGMB has been traditionally used in Korean medicine for treating various digestive diseases. We tested it on the rat reflux esophagitis (RE) induced by pylorus and forestomach ligation in rats as compared with omeprazole, a well-known proton pump inhibitor. Method : Three different dosages of YJGMB 200, 100 and 50mg/kg, were orally pretreated once a day for 28 days before pylorus and forestomach ligation. Seven groups, each of 8 rats per group were used in the study. Six hours after pylorus and forestomach ligation, changes of the stomach and esophagus lesion areas, gastric volumes, acid and pepsin outputs, invasive lesion percentages, fundic mucosa and total thicknesses were measured as histomorphometry. The results were compared with omeprazole, antioxidant and proton pump inhibitor, and 30 and 10mg/kg treated groups in which the effects on RE were already confirmed. Results : As results of pylorus and forestomach ligation, marked increases of esophageal and gastric mucosa lesion areas, gastric volumes, acid outputs, pepsin outputs were observed with histopathological changes of RE, such as hemorrhages, ulcerative lesions and edematous changes on the fundic mucosa. However, these pylorus and forestomach ligation-induced RE were dose-dependently inhibited by treatment of 200, 100 and 50mg/kg of YJGMB. YJGMB 200mg/kg showed similar protective effects as compared with 30mg/kg of omeprazole in the present study, and more favorable effects were observed in 50mg/kg of YJGMB treated rats as compared with omeprazole 10mg/kg in the present study. Conclusion : The results obtained in this study suggest that YJGMB has favorable protective effects on the RE induced by pylorus and forestomach ligation. Therefore, it is expected that YJGMB will also show favorable effects on RE corresponding well to the suggestion of traditional Korean medicine. However, more detailed mechanism studies should be conducted in future with the screening of the biological active chemical compounds in herbs.

• 대한의용생체공학회:의공학회지
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• 제40권5호
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• pp.197-205
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• 2019

The existing Extracorporeal membrane oxygenation(ECMO) and Cardiopulmonary bypass system(CPB) have been developed and applied to various devices according to their respective indications. However, due to the complicated configuration and difficult usage method, it causes inconvenience to users and there is a risk of an accident. Therefore, smart all-in-one cardiopulmonary circulation device is being developed recently. The smart all-in-one cardiopulmonary assist device consists of a blood pump for cardiopulmonary bypass, a blood oxidizer for cardiopulmonary bypass, a blood circuit for cardiopulmonary bypass, and an artificial cardiopulmonary device. It is an integrated cardiopulmonary bypass device that can be used for a variety of purposes such as emergency, intraoperative, post-operative intensive care, and long-term cardiopulmonary assist, combined with CPB used in open heart surgery and ECMO used when patient's cardiopulmonary function does not work normally. The smart all-in-one cardiopulmonary assist device does not exist as a standard and international standard applicable to advanced medical devices. Therefore, in this study, we will refer to the International Standard for Blood Components, the International Standard for Blood, the Guideline for Blood Products, and prepare applicable performance and safety guidelines to help quality control of medical devices, and contribute to the improvement of the health of people. The guideline, which is the result of conducted a survey of the method of safety and performance test, is based on the principle of all-in-one cardiopulmonary aiding device, related domestic foreign standards, the status of domestic and foreign patents, related literature, blood pump(ISO 18242), blood oxygenator (ISO 7199), and blood circuit (ISO 15676) for cardiopulmonary bypass.The items on blood safety are as follows: American Society for Testing and Materials ASTM F1841-97R17), and in the 2010 Food and Drug Administration's Safety Assessment Guidelines for Medical Assisted Circulatory Devices. In addition, after reviewing the guidelines drawn up through expert consultation bodies including manufacturers / importers, testing inspectors, academia, etc. the final guideline was established through revision and supplementation process. Therefore, we propose guidelines for evaluating the safety and performance of smart all-in-one cardiopulmonary assist devices in line with growing technology.

• 농약과학회지
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• 제20권3호
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• pp.271-279
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• 2016

전신복장법(whole body dosimetry, WBD)을 이용한 사과 과수원 농약 살포자의 살포농약 조제 및 살포 과정 중 imidacloprid 수화제 사용에 의한 노출 특성 및 위해성을 평가하기 위하여 농약 살포 전 방제복, 장갑, 마스크, 호흡 노출량 측정 장치를 착용한 후 speed sprayer를 이용하여 acephate+imidacloprid 25(20+5)% 1,000배 희석액을 3,000 L/ha/살포자의 비율로 청주 인근의 10개 사과 과수원에 살포하였다. 노출시험은 조제자와 살포자에 대하여 각각 나누어 수행하였다. 시험농약은 HPLC-DAD를 이용하여 분석하였으며, 부위별 평균 회수율은 81.5-108.6%, 평균 포장회수율은 73.8-86.7%로서 모두 적합하였다. 조제자 및 살포자의 노출량은 imidacloprid 총량 대비 0.0014-0.0279%이었으며, 조제자와 살포자 모두 장갑의 노출량이 가장 높았다. 또한 농약 살포자의 농약 사용에 대한 위해성을 측정하기 위한 안전한계(margin of safety, MOS)는 조제자와 살포자 각각 97-355, 46-196으로서 speed sprayer를 이용한 imidacloprid 살포 시 사과 과수원 농약 살포자에 대한 위해도는 매우 낮았다.

• Journal of Biosystems Engineering
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• 제33권6호
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• pp.371-378
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• 2008

Bio-diesel applications seem to be extended due to bio-diesel policies and changes of agricultural environment. This study was conducted to develop a rapeseed reaping equipment attachable to the conventional combine. This paper was intended to report concept design, process and manufacturing of the prototype rapeseed reaping equipment. For concept design, physical properties of "SUNMANG", which is a typical rapeseed as bio-diesel materials, were considered. The designed prototype rapeseed reaping equipment consisted of wide-width plates, finger type knifes, side cutter knifes and drive equipments. The wide-width plate is 2.1 m wide, 0.7 m long, and 0.002 m thick. The finger type cutter knifes have 14.5 fingers, 30 knifes, and the specification was 7.6 cm of pitch, 8.3 cm of length and $21^{\circ}$ of cutting angle. The side cutter knifes consisted of a hydraulic pump, a hydraulic motor, a flow control and a relief valve, a hydraulic hose, a driving equipment and a reciprocating cutter knife. The 18 reciprocating cutter knifes were 137 cm long and knife pitch, knife length and cutting angle were 7.7 cm, 10.5 cm, and $18^{\circ}$. Prototype weight of the rapeseed reaping equipment was heavier by 272 kg when compared with the manual reaping equipments. Load distributions of left and right side showed 50% and 49%, and those of front and rear side showed 64% and 36%. Static turn-over angles in left and right of the prototype were $38.1^{\circ}$ and $38.7^{\circ}$, respectively. The designed prototype rapeseed reaping equipment was properly mounted at the front of a conventional combine.

• 한국연소학회지
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• 제7권4호
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• pp.36-44
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• 2002

Carbon molecules with closed-cage structures are called fullerenes $(C_{60},\;C_{70})$, whose applications include super-conductors, sensors, catalysts, optical and electronic device, polymer composites, and biological and medical materials. The synthesis of fullerenes has been recently studied with low-pressure benzene/argon/oxygen flames. The formation of fullerene is known as molecular weight growth processes of PAHs (polycyclic aromatic hydrocarbon). This study presents results of PAHs and fullerene measurements performed in a low-pressure benzene/argon/oxygen normal co-flow laminar diffusion flame. Through the central tube of the burner, benzene vapors carried by argon are injected. The benzene vapors are made in a temperature-controlled bubbler. The burner is located in a chamber, equipped with a sampling system for direct collection of condensable species from the flame, and exhausted to a vacuum pump. Samples of the condensable are analyzed by HPLC (High Performance Liquid Chromatography) to determine the yields of PAHs and fullerene. Also, we computed mole fraction of fullerene and PAHs in a nearly sooting low pressure premixed, one-dimensional benzene/argon/oxygen flame (equivalence ratio ${\Phi}=2.4$, pressure=5.33kPa). The object of computation was to investigate the formation mechanism of fullerenes and PAHs. The computations were performed with CHEMKIN/PREMIX. As a result of this study, fullerenes were synthesized in a low pressure (20torr) $C_6H_6/Ar/O_2$ flames and the highest concentration of fullerene was detected just above the visible surface of a flame.