• 대한의용생체공학회:의공학회지
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• 제35권4호
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• pp.81-86
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• 2014

One of the methods for Parkinson's disease(PD) tremor evaluation is the Clinical Tremor Rating Scale(CTRS). However, the method has some limitations that clinician ratings can vary because the scores are subjectively rated. In addition, most researches usually collected data measured on the more affected arm. In this study, we developed a portable wearable system(SNUMAP system) for measuring PD tremor. The SNUMAP system captures 3-dimensional motion using tri-accelerometer and tri-gyroscope on finger and wrist. 40 PD patients participated in resting tremor and postural tremor tasks, while wearing the system on both hands simultaneously. Estimated tremor scores from Leave-One-Out Cross Validation for regression were highly correlated to the average clinician CTRS scores for rest tremor($r^2$ = 0.87, RMSE = 0.48) and postural tremor($r^2$ = 0.82, RMSE = 0.48). Therefore, the quantitative assessment model can improve treatment of PD patients.

• 디지털융복합연구
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• 제15권12호
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• pp.509-516
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• 2017

사람들은 항상 사건들과 접하고 말소리 지각과 같은 사건을 지각하는데 별 어려움이 없다. 생물학적 운동의 지각과 마찬가지로, 말소리 지각에 대한 두 이론이 논쟁해 왔다. 이 논문의 목적은 말소리 지각에 대해 설명하고 말소리 지각에 대한 운동이론과 직접지각 이론을 비교하는 것이다. 운동이론학자들은 인간은 운동신경의 명령에 의해 말소리를 지각하고 생성해 내기 때문에 인간은 말소리 지각에 있어서 특별한 감각을 가지고 있다고 주장해 왔다. 하지만, 직접지각 이론학자들은 말소리 지각은 여느 다른 소리를 지각하는 것과 다르지 않다고 제안했다. 왜냐하면, 말소리를 지각하는 것은 다른 모든 사건을 지각하는 것과 마찬가지로 필요한 정보를 직접 탐지하면 되기 때문이다. 음성공학과의 융합에 있어서 이러한 인간의 기본적인 말소리 지각 능력을 먼저 이해하는 것이 중요하다. 따라서 이러한 말소리 지각에 대한 기본적인 이해는 인공 지능, 음성 인식 기술, 음성 인식 시스템 등에 사용될 수 있을 것으로 기대된다.

• 대한의용생체공학회:의공학회지
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• 제21권3호
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• pp.285-293
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• 2000

나이에 의한 외부의 환경조건의 변화는 이에 적응하려는 척추의 구조적인 변화를 가져온다. 이러한 구조적인 변화는 척추의 biomechanical 거동에 영향을 미칠 것이다. 이러한 구조적인 변화의 효과를 연구하기 위하여, 나이에 의한 척추의 재료 및 기계적인 물성의 변화는 제외되었다. 유한요소법 (finite element method)에 의한 lumbar spine model (L3-L4)에 있어서, Annulus 의 유한요소 모델은 laminate composite elements로서 16개의 layer와 6개의 물성으로 구성되어있다. Spinal stiffness 와 facet reaction은 나이가 들수록 증가했다. 나이가 들수록 inner annulus의 fiber/layer tensile strains, cancellous bone stress 및 end-Plate stress는 감소했다. Fiber/layer compressive strains, facet reaction, ligament reaction and end-plate rigidity는 나이에 의한 척추의 구조적인 변화에 의하여 증가했다. 따라서 나이에 의한 척추의 정상적인 쇠퇴과정에 있어서 척추의 구조적인 변화는 spinal stiffness를 증가 시켜서 척추 및 disc의 지나친 변형을 감소시킬 것이다.

• 대한의용생체공학회:의공학회지
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• 제24권4호
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• pp.309-318
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• 2003

본 연구는 현재 산업용으로 널리 사용되고 있는 수직 다관절 6자유도 로봇을 의료용 목적으로 적용하기 위해 수행하였다. 이미 산업용으로 제안되어 검증된 로봇을 사용한다면 비용, 시간적인 면에서 상당한 잇점이 있다. 따라서 본 논문에서는 산업용으로 제안된 로봇을 의료 목적으로 사용하여 연구하였다. 본 시스템은 뇌졸중 환자와 같이 한쪽 팔을 다친 사람들을 위해 제안하였다. 한쪽 팔이 비정상이고 다른 팔이 정상인 환자를 대상으로 정상인 팔의 움직임을 획득하여 마비되거나 정상으로 움직이기 어려운 팔을 운동시키도록 마스터-슬레이브 시스템을 구성하였다. 또한 팔꿈치와 어깨의 기구학을 해석하기 위하여 기존의 인체에 관한 연구 결과를 적용하였다. 또한 슬레이브 로봇에 힘 센서를 부착하여 환자의 재활 정도를 측정할 수 있도록 하였으며, 위험 상황에 대비함으로써 슬레이브 로봇의 안전성을 높였다. 이러한 시스템으로 인해 물리치료사의 도움 없이 환자 혼자 운동이 가능하도록 시스템을 구성하였다. 제안된 시스템과 제어 알고리즘은 실험과 시뮬레이션을 통하여 타당성을 검증하였다.

• 대한의용생체공학회:의공학회지
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• 제29권3호
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• pp.212-221
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• 2008

The total hip replacement (THR) has been used as the most effective way to restore the function of damaged hip joint. However, various factors have caused some side effects after the THR. Unfortunately, the success of the THR have been decided only by the proficiency of surgeons so far. Hence, It is necessary to find the way to minimize the side effect caused by those factors. The purpose of this study was to suggest the definite data, which can be used to design and choose the optimal hip implant. Using finite element analysis (FEA), the biomechanical condition of bone cement was evaluated. Stress patterns were analyzed in three conditions: cement mantle, procimal femur and stem-cement contact surface. Additionally, micro-motion was analyzed in the stem-cement contact surface. The 3-D femur model was reconstructed from 2-D computerized tomography (CT) images. Raw CT images were preprocessed by image processing technique (i.e. edge detection). In this study, automated edge detection system was created by MATLAB coding for effective and rapid image processing. The 3-D femur model was reconstructed based on anatomical parameters. The stem shape was designed using that parameters. The analysis of the finite element models was performed with the variation of parameters. The biomechanical influence of each parameter was analyzed and derived optimal parameters. Moreover, the results of FE A using commercial stem model (Zimmer's V erSys) were similar to the results of stem model that was used in this study. Through the study, the improved designs and optimal factors for clinical application were suggested. We expect that the results can suggest solutions to minimize various side effects.

• Journal of Korean Neurosurgical Society
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• 제37권5호
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• pp.364-369
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• 2005

Objective: Spinal instrumentation without fusion often fails due to biological failure of intervertebral joints (spontaneous fusion, degeneration, etc). The purpose of this study is to investigate the influence of fixation rigidity on viability of intervertebral joints. Methods: Twenty pigs in growing period were subjected to posterior segmental fixation. Twelve were fixed with a rigid fixation system(RF) while eight were fixed with a flexible unconstrained implant(FF). At the time of the surgery, a scoliosis was created to monitor fixation adequacy. The pigs were subjected to periodic radiological examinations and 12pigs (six in RF, six in FF) were euthanized at 12-18months postoperatively for analysis. Results: The initial scoliotic curve was reduced from $31{\pm}5^{\circ}$ to $27{\pm}8^{\circ}$ in RF group (p=0.37) and from $19{\pm}4^{\circ}$ to $17{\pm}5^{\circ}$ in FF group (p=0.21). Although severe disc degeneration and spontaneous fusion of facet joints were observed in RF group, disc heights of FF group were well maintained without major signs of degeneration. Conclusion: The viability of the intervertebral joints depends on motion spinal fixation. Systems allowing intervertebral micromotion may preserve the viability of intervertebral discs and the facet joint articular cartilages while maintaining a reasonably stable fixation.

• 대한원격탐사학회지
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• 제15권4호
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• pp.297-305
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• 1999

Ocean Scanning Multispectral Imager (OSMI) is a payload on the KOMPSAT satellite to perform global ocean color monitoring for the study of biological oceanography. The instrument images the ocean surface using a wisk-broom motion with a swath width of 800km and a ground sample distance (GSD) of < 1km over the entire field of view (FOV). The instrument is designed to have an on-orbit operation duty cycle of 20% over the mission lifetime of 3 years with the functions of programmable gain/offset and on-board image data compression/storage. The instrument also performs sun and dark calibration for on-board instrument calibration. The OSMI instrument is a multi-spectral imager covering the spectral range from 400nm to 900nm using CCD Focal Plane Array (FPA). The ocean colors are monitored using 6 spectral channels that can be selected via ground commands. KOMPSAT satellite with OSMI was integrated and the satellite level environment tests including instrument aliveness/functional test, such as launch environment, on-orbit environment (Thermal/Vacuum) and EMI/EMC test were performed at KARl. Test results met the requirements and the OSMI data were collected and analyzed during each test phase. The instrument is launched on the KOMPSAT satellite on December 21,1999 and is scheduled to start collecting ocean color data in the early 2000 upon completion of on-orbit instrument checkout.

• Biomedical Engineering Letters
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• 제8권4호
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• pp.365-371
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• 2018

Uninterrupted monitoring of multiple subjects is required for mass causality events, in hospital environment or for sports by medical technicians or physicians. Movement of subjects under monitoring requires such system to be wireless, sometimes demands multiple transmitters and a receiver as a base station and monitored parameter must not be corrupted by any noise before further diagnosis. A Bluetooth Piconet network is visualized, where each subject carries a Bluetooth transmitter module that acquires vital sign continuously and relays to Bluetooth enabled device where, further signal processing is done. In this paper, a wireless network is realized to capture ECG of two subjects performing different activities like cycling, jogging, staircase climbing at 100 Hz frequency using prototyped Bluetooth module. The paper demonstrates removal of baseline drift using Fast Fourier Transform and Inverse Fast Fourier Transform and removal of high frequency noise using moving average and S-Golay algorithm. Experimental results highlight the efficacy of the proposed work to monitor any vital sign parameters of multiple subjects simultaneously. The importance of removing baseline drift before high frequency noise removal is shown using experimental results. It is possible to use Bluetooth Piconet frame work to capture ECG simultaneously for more than two subjects. For the applications where there will be larger body movement, baseline drift removal is a major concern and hence along with wireless transmission issues, baseline drift removal before high frequency noise removal is necessary for further feature extraction.

• 대한의용생체공학회:의공학회지
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• 제42권3호
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• pp.107-115
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• 2021

Purpose: The aim of this study is to find the location of acupoints that are effective for increasing parasympathetic nervous system(PNS) activity among acupoints used to relieve symptoms such as dizziness and nausea. Materials and Methods: Twenty healthy adult men participated in this experiment. Transcutaneous electrical nerve stimulation(TENS) was applied to P6(Neiguan), ST36(Zusanli) and BL20(Pishu) for 30 minutes. For 5 minutes before and after stimulation, Electrocardiogram(ECG), Electrodermal activity(EDA), Respiration, and Skin temperature(SKT) were measured using biosignalsplux Professional(biosignalsplux; Portugal). Paired t-test was performed for the results before and after stimulation, and a one-way ANOVA test between stimulations was performed for the rate of change before and after stimulation. Results: When each acupoint was stimulated with TENS, it was found that the PNS was generally activated. In addition, when considering the change in biosignals after stimulation, the participants stimulated with P6 showed the most consistent results. Conclusion: As a result of stimulating each acupoint, it was found that stimulating P6 can effectively increase PNS activity. These results indicate that methods of stimulating P6 may be most effective in alleviating symptoms of motion sickness.

• 대한치과보철학회지
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• 제60권4호
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• pp.382-394
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• 2022

심한 치주염을 가진 환자의 치료는 환자의 개개 치아의 정확한 진단과 전략적인 치료 계획을 통해 단계적으로 진행되어야 한다. 임플란트 지지 고정성 보철 수복은 국소의치에 비해 환자의 만족도가 높고, 안정적인 수직 고경을 유지할 수 있는 장점이 있지만, 경조직이 부족한 다수 치아 결손 부위에서는 심미적인 측면의 실패와 치료 기간이 길어진다는 점의 단점이 있을 수 있다. 또한 통상의 고정성 보철물을 제작하고 장착하는 데에는 일정 기간이 소요되는데, 이 기간 동안 임시 보철물은 치아의 기계적, 생물학적, 심미적 요구 조건을 만족시켜야 한다. 이번 증례 보고에서는 상악과 하악의 부분 무치악 환자에서 단계적인 접근을 통한 임플란트 고정성 보철물을 수복한 증례를 보고하고자 한다.