• 제목/요약/키워드: Biological Effect

검색결과 5,994건 처리시간 0.03초

기초간호학만족도가 임상수행능력에 미치는 효과 경로에 관한 융합 연구 (A Convergence Study about the Effect Path of Satisfaction with Biological nursing science on Clinical competence)

  • 임정혜
    • 한국융합학회논문지
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    • 제10권7호
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    • pp.421-429
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    • 2019
  • 본 연구는 기초간호학만족도, 전공간호학만족도, 비판적사고성향과 전공만족도 및 임상수행능력 간의 인관관계와 경로를 파악하기 위한 융합연구이다. 3개 대학 간호학과 학생 203명을 대상으로, 2018년 5월에 구조화된 설문지를 이용하여 수집하였다. PASW 18.0, AMOS 18.0을 이용하여 분석하였다. 연구결과 기초간호학만족도가 임상수행능력에 미치는 효과 경로모형은 적합하였다(${\chi}^2/DF=1.093$, GFI=.992, AGFI=.968, RMSEA=.021, CFI=.998, NFI=.983). 기초간호학만족도는 전공간호학만족도(${\beta}=.345$), 전공간호학만족도는 비판적사고성향(${\beta}=.272$)과 전공만족도(${\beta}=.277$), 비판적사고성향은 전공만족도(${\beta}=.365$)와 임상수행능력(${\beta}=.582$), 전공만족도는 임상수행능력(${\beta}=.228$)에 직접효과가 있음이 유의하게 나타났다. 기초간호학만족도가 높으면 전공간호학만족도가 높아지고, 이는 비판적사고성향과 전공만족도를 높이며, 결국에는 임상수행능력을 향상시키는 것임을 확인하였다. 이에 다양한 교수학습방법 개발과 적용으로 기초간호학만족도를 높일 수 있는 중재마련이 필요하다.

Gene Expression Profiling of Rewarding Effect in Methamphetamine Treated Bax-deficient Mouse

  • Ryu, Na-Kyung;Yang, Moon-Hee;Jung, Min-Seok;Jeon, Jeong-Ok;Kim, Kee-Won;Park, Jong-Hoon
    • BMB Reports
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    • 제40권4호
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    • pp.475-485
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    • 2007
  • Methamphetamine is an illicit drug that is often abused and can cause neuropsychiatric and neurotoxic damage. Repeated administration of psychostimulants such as methamphetamine induces a behavioral sensitization. According to a previous study, Bax was involved in neurotoxicity by methamphetamine, but the function of Bax in rewarding effect has not yet been elucidated. Therefore, we have studied the function of Bax in a rewarding effect model. In the present study, we treated chronic methamphetamine exposure in a Bax-deficient mouse model and examined behavioral change using a conditioned place preference (CPP) test. The CPP score in Bax knockout mice was decreased compared to that of wild-type mice. Therefore, we screened for Bax-related genes that are involved in rewarding effect using microarray technology. In order to confirm microarray data, we applied the RT-PCR method to observe relative changes of Bcl2, a pro-apoptotic family gene. As a result, using our experiment microarray, we selected genes that were associated with Bax in microarray data, and eventually selected the Tgfbr2 gene. Expression of the Tgfbr2 gene was decreased by methamphetamine in Bax knockout mice, and the gene was overexpressed in Bax wild-type mice. Additionally, we confirmed that Creb, FosB, and c-Fos were related to rewarding effect and Bax using immunohistochemistry.

토양 내 은나노 처리 시 비료에 의한 염류 효과 (Overview of Salt Effect of Fertilizer on Nano-Silver Application in Soil)

  • 양재의;김성철;이윤수;김동국
    • 한국토양비료학회지
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    • 제42권Spc호
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    • pp.1-3
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    • 2009
  • 은나노입자는 살균 효과 때문에 농업현장에서 사용되고 있다. 그러나 은나노입자가 토질에 미치는 영향에 대해서는 아직 많은 정보가 없다. 그러므로 비료가 처리 되었을 때 특히 토양에 은나노입자를 처리한 효과에 대한 검증이 반드시 필요하다. 가리계 비료를 모의 실험하기 위해서 토양에 염화가리를 은나노입자와 함께 처리하였다. 은과 염소의 농도는 처리 후 78 내지 84% 그리고 kg 당 3.4 mg 정도 감소하는 경향을 보였다. 그리고 은나노입자와 염화가리를 혼합하였을 때 미생물의 숫자가 증가하였다. 이러한 결과로부터 비료시용은 토양에서 은나노입자의 살생물 효과에 영향을 미친다.

Service life of concrete culverts repaired with biological sulfate-resisting mortars

  • Hyun-Sub, Yoon;Keun-Hyeok, Yang;Nguyen, Van Tuan;Seung-Jun, Kwon
    • Computers and Concrete
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    • 제30권6호
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    • pp.409-419
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    • 2022
  • The purpose of this study is to examine the effectiveness of biological repairing mortars on restoring the structural performance of a sewage culvert deteriorated by sulfate attack. The biological mortars were developed for protecting concrete structures exposed to sulfate attack based on the block membrane action of the bacterial glycocalyx. The diffusion coefficient of sulfate ions in the biological mortars was determined from the natural diffusion cell tests. The effect of sulfate-attack-induced concrete deterioration on the structural performance of culverts was examined by using the moment-curvature relationship predicted based on the nonlinear section lamina approach considering the sulfuric-acid-induced degradation of the structure. Typical analytical assessments showed that biological mortars were quite effective in increasing the sulfate-resistant service life of sewage culverts.

치료약물과 신경영상 (Psychotropic Drugs and Neuroimaging)

  • 정은기
    • 생물정신의학
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    • 제2권1호
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    • pp.38-43
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    • 1995
  • The application of neuroimaging techniques in psychiatry started in 1970s with the use of CT(computerized tomography). Neuroimaging methods can be categorized as anatomical and functional. Recently, attentions are focused on the functional neuroimaging methods those could give us various important informations. But results regarding to psychotropic medication effect on neuroimaging are not sufficient. Here, the study results of the medication effect with the functional imaging methods are mainly revieued.

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Antimutagenic Effect of Bacillus natto Isolated from Natto

  • Yun, Soon-Il
    • Journal of Applied Biological Chemistry
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    • 제48권3호
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    • pp.133-137
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    • 2005
  • In vitro antimutagenicity of Bacillus natto islolated from Natto, Japanese traditional fermented food, was investigated using umu-test. Mutagenicity of S9-activated metabolites of Trp-P-2 and IQ for Salmonella typhimurium TA 1535/pSK1002 was remarkably inhibited by addition of bacterial cells and their cytoplasmic fraction. Desmutagenicity by cytoplasmic fraction increased with increasing concentration of the fraction. Bioantimutagenic effect of cytoplasm on Salmonella typhimurium SD-100 did not show bioantimutagenic activity against mutated bacterial cells induced by Trp-P-2. Cytoplasmic fraction exhibited 17% bioantimutagenicity due to desmutation caused by IQ.

ON A LOTKA-VOLTERRA TYPE SIMPLE FOOD-CHAIN MODEL

  • Ko, Wonlyul;Ryu, Kimun
    • 충청수학회지
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    • 제20권3호
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    • pp.231-243
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    • 2007
  • In this paper, we study a Lotka-Volterra type simple food chain model. We investigate the positive coexistence of the steady states to the model and give some results for the extinction of species under certain assumptions which can be interpreted as Domino effect and Biological control. The methods of a decoupling operator and the fixed point index theory on a positive cone are used as well as the comparison argument. Numerical evidences for our results also are provided.

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아닐링 처리가 밭벼와 논벼 찹쌀 전분의 호화에 미치는 영향 (Effect of annealing treatment on gelatinization of upland and lowland waxy brown rice starches)

  • 김성곤
    • Applied Biological Chemistry
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    • 제34권2호
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    • pp.187-189
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    • 1991
  • Gelatinization temperatures of upland and lowland waxy brown rice starches annealed at $25^{\circ}C$ and $60^{\circ}C$ for 24hr were investigated with differential scanning calorimetry No annealing effect was observed at low temperature. The upland rice starch showed narrower range of gelatinization temperature upon annealing treatment at $60\circ}C$ compared with the lowland rice starch. The enthalpy of gelatinization was not changed in case of the upland rice starch but was increased in case of the lowland one upon annealing.

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