• Title/Summary/Keyword: Biologic

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Use Biologic Fibrin Adhesive in Otologic Surgery : Compared with Ammonium Sulfate Fibrin Adhesive and Tisseel$^{(R)}$ (중이수술에 인체에서 추출한 Fibrin 접착제의 이용 : Ammonium Sulfate fibrin 접착제와 Tisseel$^{(R)}$의 비교)

  • Lee, Hyung-Chul;Yang, Mi-Gyeung;Park, Mun-Heum
    • Journal of Yeungnam Medical Science
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    • v.8 no.1
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    • pp.127-135
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    • 1991
  • Successful middle ear surgery requires the availability of al safe, effective bonding material. Side effect caused by synthetic materials have led to the use of biologic adhesive. However, they carry the risk of transmission of infectious diseases if they are prepared from pooled human blood. The adhesive strength of ammonium sulfate fibrin adhesive produce an adhesive strength that is half that of the homologous commercial product. It is, however, good enough for use in several otolaryngological operations, tympanoplasty, facial nerve repair, reconstruction of ossicles, reconstruction of posterior wall of ear canal and obliteration of frontal sinus and mastoid antrum using bone dust.

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BIOLOGIGIC MEMBRANE FOR GUIDED BONE REGENERATION (골 재생을 위한 생물학적 유도막)

  • Hong, Jong-Rak;Kang, Na-Ra;Choung, Pill-Hoon
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.30 no.1
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    • pp.17-24
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    • 2004
  • The purpose of this study was to evaluate the stability and efficacy of biologic membrane made of freeze-dried cartilage as a barrier to facilitate guided bone regeneration in experimental non-healing bone defects in the rat mandible. Nine adult Sprague-Dawley rats (400-500g) were used in experiment. 5.0mm in diameter were created on the mandibular angle area by means of slow-speed trephine drill. In microscopic examination, dynamic immature bone forming at 2 weeks and its calcification at 4 weeks were observed. The membrane made of lyophilized cartilage taken from human costal cartilage seems to be very effective for guided bone regeneration as a biologic membrane and the scaffold for attachment of cells or local drug delivery system of growth factor, which may meet the ideal requirement of a barrier membrane and graft materials.

Mineral Trioxide Aggregate (MTA): Review of its biologic properties (Mineral trioxide Aggregate(MAT)의 생물학적 기전에 대한 고찰)

  • Kim, Eui-Seong;Shin, Su-Jung
    • The Journal of the Korean dental association
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    • v.48 no.11
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    • pp.798-802
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    • 2010
  • Introduction: MTA has been studied for more than 15 years since it was introduced and developed at Loma Linda University. The purpose of this review was to present the current published papers regarding MTA's biologic properties and to provide a deep insight into the material's mechanisms of actions. Results: MTA has appeared to be biocompatible in many previous researches. In addition to that, it had a potential to increase cell reactions such as proliferation and differentiation, Recently, MTA like new endodontic materials has been introduced and marketed. Conclusions: On the basis of current evidences, MT A seems to be biocompatible. Meticulous studies need to be performed to adopt new endodontic materials into clinical applications,