• 제목/요약/키워드: Biochemical Change

검색결과 477건 처리시간 0.023초

Serial values for hematologic and biochemical analysis after myocardial infarction in rats

  • Lee, Mi-Jin;Tae, Hyun-Jin;Li, Ying-Hua;Yu, Do-Hyeon;Han, In-Ae;Lee, Seok-Won;Ahn, Dong-Choon;Kim, In-Shik;Park, Jin-Ho
    • 한국동물위생학회지
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    • 제31권2호
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    • pp.175-186
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    • 2008
  • To diagnose acute myocardial infarction (MI), many cardiac markers have been used in hematologic and biochemical analysis, and many studies have been published for hematologic and biochemical analysis associated with human acute MI. However, after occurrence of acute MI, the serial investigation for values in hematologic and biochemical analysis including chronic MI has rarely been performed. To observe the change of the serial values in hematologic and biochemical analysis, we induced artificial MI. The left main descending artery (LMDA) of the left coronary artery was ligated during the progression (day 1, 3, 5, 7, 14 and 30) of MI. Total 66 Sprague-Dawley rats were divided into the sham group (n=24, thoracotomy without LMDA ligation) and the experimental (MI) group (n=42, with LMDA ligation). And all individual in each group was sacrified at day 1, 3, 5, 7, 14 and 30 for the hematologic and biochemical analysis. In comparison of hematologic analysis between the sham and MI groups, the mean values of red blood cell (RBCs), hemoglobin and hematocrit (HCT) showed a steady increase. In biochemical analysis, the mean values of glucose, cholesterol, total creatine kinase (CK) and isoenzyme MB, and lactate dehydrogenase (LDH) were increased in all MI groups compared with the sham groups. The results of this study suggest that early hematologic and biochemical mean values occurred after acute MI are similar to those of human acute MI. In conclusion, we could observe the alterations and serial values in hematologic and biochemical analysis to the extent of chronic status after acute MI.

청심연자탕(淸心蓮子湯)과 태음조위탕(太陰調胃湯)이 Wistar rat의 노화(老化)에 미치는 영향 (Studies of Chengsimyeonja-tang and Taeumjowi-tang that Get Change by Wistar rat's Aging)

  • 안택원;이현;주입산
    • 사상체질의학회지
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    • 제17권2호
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    • pp.74-84
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    • 2005
  • 1. Objectives The purpose of this study is to find out effects of Choeongsimyeonja-tang and Taeumjowi-tang on the against decline of physical function as aging. 2. Methods In Wistar rat 10, 30, 50 week and 40 week Choeongsimyeonja-tang & Taeumjowi-tang between 10 weeks form condition change of weight, change of intestine weight, hematology, blood chemistry, research result about serum content following conclusion get. 3. Results and Conclusions 1. Observed gain in weight than control group form of Cheongsimyeonja-tang & Taeumjowi-tang to aged Wistar rat. 2. Is thought to promote activation of living body action gaining intestine weight along with gain in weight. 3. Displayed decrease of MDA's content of serum than control group form of Cheongsimyeonja-tang & Taeumjowi-tang to aged Wistar rat. 4. Change that is Wistar rat's hematological value by aging according to 10, 30, 50 week WBC, RBC, Hgb, monocyces, eosinophil ere. increase, and HCT, PLT ere. showed tendency that decrease accorcling to old-week, and observed improvement that is hematological value than control group form of Cheongsimyeonja-tang & Taeumjowi-tang.5. Change that is Wistar rat's biochemical value by aging was measured highest in 50 week because ALT, AST, BUN, CRN, T-bili., T-chol., TG, TP, ALB, A/G. P ete. increase according to 10, 30, 50 week, and observed improvement that is biochemical value than control group form of Cheongsimyeonja-tang & Taeumjowi-tang. Is considered by being effect that Cheongsimyeonja-tang & Taeumjowi-tang living body function decline by aging by this result.

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십이미관중탕(十二味寬中湯)이 Wister rat의 노화에 따른 변화에 미치는 실험적(實驗的) 고찰(考察) (Studies of SipIMiGwanJungTang that get weight, hematology, biochemistry change by Wistar rat's aging)

  • 최예원;안택원
    • 혜화의학회지
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    • 제13권2호
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    • pp.317-326
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    • 2004
  • Administrating PalMoolGoonJaTang and SipIMiGwanJungTang to 40-weeks-(old Wistar rat for 10 weeks so, I researched into weight change, weight change of internal organ, and hemtological and serological changews. Then I got these conclusions. 1. Observed gain in weight than control group form of SipIMiGwanJungTang to aged Wistar rat. 2. Is thought to promote activation of living body action gaining intestine weight along with gain in weight. 3. Displayed decrease of MDA's content of serum than control group form of SipIMiGwan JungTang to aged Wistar rat. 4. Change that is Wistar rat's hematological value by aging according to 10, 30, 50 week WBC, RBC, Hgb, monocytes, eosinophil etc. increase, and HCT, PLT etc. showed tendency that decrease according to old-week, and observed improvement that is hematological value than control group form of SipIMiGwanJungTang 5. Change that is Wistar rat's biochemical value by aging was measured highest in 50 week because ALT, AST, BUN, CRN, T-bili., T-chol., TG, TP, ALB, A/G, P etc. increase according to 10, 30, 50 week, and observed improvement that is biochemical value than control group form of SipIMiGwanJungTang As those results, PalmoolGoonJaTang and SipIMiGwanJungTang are effective against dacline of physical function as aging. Moreover, considered to the serogical results, SipIMiGwanJungTang is much more effective than the other.

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고주파요법과 갯장어 추출물 병행처리가 남성피부에 미치는 영향 (Combined Treatment Effect of High Frequency Therapy with Sharp-Toothed Eel Extract on Men's Skin)

  • 노현주;김윤수;남형근;신현재;류은미;나명순;안병권;최두복;차월석
    • KSBB Journal
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    • 제26권3호
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    • pp.260-265
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    • 2011
  • This study aimed to examine the treatment effect of Muraenesox cinereus extract product combined with high frequency on men's damaged skin. The subjects were treated by a product containing M. cinereus extract combined with high frequency therapy for six weeks and tested in skin condition. First, for moisture level change, there was no significant difference between the control group treated only by high frequency therapy and the experimental group treated by a M. cinereus extract product combined with high frequency therapy. But the subjects who increased consistently in moisture level in the cheek and chin were more common in the experimental group. Second, for an oil level, prominently high increase was found in both the control group and the experimental group. Finally, for a rough level, while there was little difference in the control group between immediately after peeling and after six weeks, high improvement effect on a curve was found in the experimental group. Based on this result, cosmetics using M. cinereus extract may have a positive effect on men's skin which is exposed to several stress factors. Accordingly, this result will contribute to developing men's functional cosmetics.

Sol-Gel 법에 의한 Polycarbonate 시트에 적용 가능한 고굴절률을 보이는 하드코팅 용액의 제조 (Preparation of Hard Coating Solutions with High Refractive Index for Polycarbonate Sheet by the Sol-Gel Method)

  • 정일엽;조경인;정상혁;박효남;송기창
    • Korean Chemical Engineering Research
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    • 제45권4호
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    • pp.335-339
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    • 2007
  • 투명 polycarbonate(PC) 시트의 낮은 표면강도 문제를 극복하기 위해, 고굴절률을 보이는 유-무기 혼성 하드코팅 용액을 Sol-Gel 법을 이용하여 제조하였다. 코팅용액은 무기물 티타니아의 전구체인 TTIP(titanium tetraisopropoxide)에 유기물을 함유한 화합물인 GPTMS[(3-glycidoxypropyl) trimethoxysilane]를 첨가하여 제조하였다. 그 후 기재인 PC 시트에 스핀 코팅시키고, 열 경화 시켜 고굴절률을 보이는 하드코팅 필름을 제조 하였다. 코팅 용액 중의 GPTMS 함유량을 변화시킴에 의해 1.53-1.61의 굴절률을 갖는 코팅 막의 제조가 가능하였다. GPTMS의 첨가량이 증가할수록 코팅막의 굴절률은 감소하였으나, 연필경도는 증가하였다.

백합식해 발효 중 생화학적 및 미생물학적 특성 변화 (Biochemical and Microbiological Changes of Hard Clam Shikhae During Fermentation)

  • 구재근;유정희;박권삼;김선영
    • 한국수산과학회지
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    • 제42권6호
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    • pp.569-573
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    • 2009
  • The biochemical and microbiological changes of the hard clam shikhae were studied during fermentation at $4-18^{\circ}C$ for 45 days. For preparation of the shikhae, the shucked hard clams were blanched into 2% saline solution and were soaked in seasoning solution before mixing with salt, cooked grain and spices. During fermentation, the initial pH steadily decreased from 5.0 to 4.6, but $NH_2-N$ and VBN concentrations increased to 127 mg/100 g and 27.0 mg/100 g, respectively. Alanine, taurine, glutamic acid, and aspartic acid concentrations increased, but arginine concentration decreased by fermentation. The major organic acids of the fermented shikhae were lactic acid, succinic acid and acetic acid. The major free sugar were maltose, glucose and fructose. The concentration of total viable cell ($2.1\times10^5$ CFU/g) and proteolytic bacteria ($1.2\times10^5$ CFU/g) increased to $4.4\times10^8$ CFU/g and $9.8\times10^7$ CFU/g, respectively until day 15 and then slightly decreased. The concentration of yeast ($2.4\times10^3$ CFU/g) increased to $1.6\times10^7$ CFU/g until day 25, but lactic acid bacteria ($5.0\times10^8$ CFU/g) increased to $5.0\times10^8$ CFU/g until day 9. Vibrio species was not detected on the TCBS agar during fermentation.

Changes in Biochemical Composition of the Digestive Gland of the Female Purple Shell, Rapana venosa, in Relation to the Ovarian Developmental Phases

  • Chung, Ee-Yung;Kim, Sung-Yeon;Park, Kwan-Ha
    • 한국패류학회지
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    • 제17권1호
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    • pp.27-33
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    • 2001
  • The Ovarian developmental phases of the reproductive cycle of Rapana venosa can be classified into five successive stages by histological study: early active stage (September to February), late active stage (December to April), ripe stage (March to July), partially spawned stage (May to August), and recovery stage (June to September). To understand the characteristics of nutrient storage and utilization in the digestive gland cells with ovarian developmental phases, we examined the digestive gland - which is the major nutrient supply organ associated with ovarian development of the female purple shell - by biochemical methods. Total protein contents in the digestive gland tissues increased in March (late active stage) and reached the maximum in May (ripe and partially spawned stages), and then their levels sharply decreased in July (partially spawned and recovery stages). Total lipid contents in the digestive gland tissues reached the maximum in January (early active stage). Thereafter, their levels rapidly decreased from May (ripe and partially spawned stages) and reached a minimum in July (partially spawned and recovery stages). The total DNA contents did not significantly change regardless of the different developmental stages of the ovary. However, it was also found from biochemical analysis that changes in total RNA content follow the same seasonal cycling to protein. These results indicate that the digestive gland is an important energy storage and supply organ in purple shells, and that the nutrient contents of the digestive gland change in response to gonadal energy needs.

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이산화탄소 분리용 세라믹 중공사 접촉막 모듈 기술 개발 (Development of Ceramic Hollow Fiber Membrane Contactor Modules for Carbon Dioxide Separation)

  • 이홍주;채진웅;박정훈
    • 한국기후변화학회지
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    • 제7권3호
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    • pp.249-256
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    • 2016
  • Porous $Al_2O_3$ hollow fiber membranes were successfully prepared by dry-wet spinning/sintering method. The SEM image shows that the $Al_2O_3$ hollow fiber membrane consists mostly of sponge pore structure. The contact angle and the breakthrough pressure were $126^{\circ}$ and 1.91 bar, respectively. This results indicate that the $Al_2O_3$ hollow fiber membranes were successfully modified to hydrophobic surface. The hydrophobic modified $Al_2O_3$ hollow fiber membranes were assembled into a membrane contactor system to separate $CO_2$ from a model gas mixture of the flue gas at elevated gas velocity. The $CO_2$ absorption flux was enhanced when the gas velocity increased from $1{\times}10^{-3}$ to $6{\times}10^{-3}$ m/s. Whereas the $CO_2$ absorption flux was decreased with the number of hollow fiber membrane of a module because of the concentration polarization. Furthermore, we developed an lab-scale $Al_2O_3$ hollow fiber membrane contactor modules and their system (i.e., $CO_2$ absorption using the $Al_2O_3$ membrane and monoethanolamine (MEA)) that could dispose of over $0.02Nm^3/h$ mixture gas (15% $CO_2$) with the removal efficiency higher than 95%. The results can be useful in a field of the membrane contactor for $CO_2$ separation, helping to design and extend a equipment.