• Title/Summary/Keyword: Bioanalysis

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Neuroprotective Mechanisms of Aloesin against Focal Ischemic Brain Injury

  • Lee, Moon-Jung;Cho, Eun-Young;Lee, Yong-Ha;Jung, Kyung-Ja;Song, Yun-Seon;Jin, Chang-Bae
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.303.1-303.1
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    • 2002
  • Recent studies have suggested that the cerebral ischemia induced the neuronal cell death by mediating multiple mechanisms with necrosis and/or apoptosis. The present study examined neuroprotective mechanism of aloesin against transient focal cerebral ischemia. Aloesin. main component of aloe possesses various biological activates such as wound healing. anti-gastric ulcer. and chemopreventive activity. Transient focal cerebral ischemia was induced by 120 min MCAO. (omitted)

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Neuroprotective Effects of Treatment with Aloesin in Rat Model of Permanent Focal Cerebral Ischemia

  • Cho, Eun-Young;Lee, Moon-Jung;Lee, Yong-Ha;Jung, Kyung-Ja;Song, Yun-Seon;Jin, Chang-Bae
    • Proceedings of the PSK Conference
    • /
    • 2002.10a
    • /
    • pp.304.1-304.1
    • /
    • 2002
  • Brain injury resulting from cerebral ischemia remains a major public health problem. Aloesin. main component of aloe possesses various biological activities such as wound healing, anti-gastric ulcer, and chemopreventive activity. In this study we investigated whether treatment with aloes in could protect brain injury induced by permanent focal cerebral ischemia in rats. We also compared aloes in with other neuroprotective. drugs such as MK801 and ebselen. (omitted)

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