Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Neuroprotective Effects of Treatment with Aloesin in Rat Model of Permanent Focal Cerebral Ischemia

  • Cho, Eun-Young (Bioanalysis ＆ Biotransformation Research Center, Korea Institute of Science and Technology) ;
  • Lee, Moon-Jung (Bioanalysis ＆ Biotransformation Research Center, Korea Institute of Science and Technolog) ;
  • Lee, Yong-Ha (Bioanalysis ＆ Biotransformation Research Center, Korea Institute of Science and Technolog) ;
  • Jung, Kyung-Ja (Bioanalysis ＆ Biotransformation Research Center, Korea Institute of Science and Technolog) ;
  • Song, Yun-Seon (Bioanalysis ＆ Biotransformation Research Center, Korea Institute of Science and Technolog) ;
  • Jin, Chang-Bae (Bioanalysis ＆ Biotransformation Research Center, Korea Institute of Science and Technology)
  • Published : 2002.10.01
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Abstract

Brain injury resulting from cerebral ischemia remains a major public health problem. Aloesin. main component of aloe possesses various biological activities such as wound healing, anti-gastric ulcer, and chemopreventive activity. In this study we investigated whether treatment with aloes in could protect brain injury induced by permanent focal cerebral ischemia in rats. We also compared aloes in with other neuroprotective. drugs such as MK801 and ebselen. (omitted)

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