Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.303.1-303.1
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- 2002
Neuroprotective Mechanisms of Aloesin against Focal Ischemic Brain Injury
- Lee, Moon-Jung (Bioanalysis ＆ Biotransformation Research Center, Korea institute of Science ＆ Technology) ;
- Cho, Eun-Young (Bioanalysis ＆ Biotransformation Research Center, Korea institute of Science ＆ Technology) ;
- Lee, Yong-Ha (Bioanalysis ＆ Biotransformation Research Center, Korea institute of Science ＆ Technology) ;
- Jung, Kyung-Ja (Bioanalysis ＆ Biotransformation Research Center, Korea institute of Science ＆ Technology) ;
- Song, Yun-Seon (Bioanalysis ＆ Biotransformation Research Center, Korea institute of Science ＆ Technology) ;
- Jin, Chang-Bae (Bioanalysis ＆ Biotransformation Research Center, Korea institute of Science ＆ Technology)
- Published : 2002.10.01
Abstract
Recent studies have suggested that the cerebral ischemia induced the neuronal cell death by mediating multiple mechanisms with necrosis and/or apoptosis. The present study examined neuroprotective mechanism of aloesin against transient focal cerebral ischemia. Aloesin. main component of aloe possesses various biological activates such as wound healing. anti-gastric ulcer. and chemopreventive activity. Transient focal cerebral ischemia was induced by 120 min MCAO. (omitted)
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