• Title/Summary/Keyword: Bio-system

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Designing a 3D-CNN for Non-Contact PPG Signal Acquisition Based on Video Imaging (영상기반 비접촉식 PPG 신호 취득을 위한 3D-CNN 설계)

  • Tae-Wan Kim;Chan-Uk ,Yeom;Keun-Chang Kawk
    • Proceedings of the Korea Information Processing Society Conference
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    • 2023.05a
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    • pp.627-629
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    • 2023
  • 생체 신호를 분석하여 사용자의 건강과 정신 상태를 예측하고, 관련 질병에 관해 예방하는 연구가 늘어나고 있다. 생체 신호 중 심박은 사람의 육체, 정신적인 상태를 반영하는 대표적인 신호이지만 기존의 접촉 패드를 통한 ECG나 광학 센서를 통한 PPG로 심박을 예측할 때는 구속적인 환경이 필요하여 일상적인 상황 속에 적용하기 어려웠다. 이러한 단점을 해결하고자 본 논문은 UBFC-RPPG 데이터셋의 동영상 프레임을 RGB 채널마다 다른 가중치를 적용하는 전처리를 하여 학습 데이터의 크기를 줄이면서 정확도를 높이고, 3D-CNN을 활용한 딥러닝으로 순간적인 영상에서도 PPG 신호를 예측할 수 있도록 1초 전처리 영상을 학습한 후, 신호를 예측하는 것을 목표로 한다. 이렇게 비접촉식으로 취득된 신호는 더 다양한 환경에서의 감정분류, 우울증 진단, 질병 감지 등 다양한 분야에 활용될 수 있다.

Design of a Semantic Segmentation Model Usingan Attention Module Based on Deformable Convolution (Deformable Convolution 기반 어텐션 모듈을 사용한 의미론적 분할 모델 설계)

  • Jin-Seong Kim;Se-Hoon Jung;Chun-Bo Sim
    • Proceedings of the Korea Information Processing Society Conference
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    • 2023.11a
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    • pp.11-13
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    • 2023
  • 의미론적 분할(Semantic Segmentation)은 이미지 내의 객체 및 배경을 픽셀 단위로 분류하는 작업으로 정밀한 탐지가 요구되는 분야에서 활발히 연구되고 있다. 기존 어텐션 기법은 의미론적 분할의 다운샘플링(Downsampling) 과정에서 발생하는 정보손실을 완화하기 위해 널리 사용됐지만 고정된 Convolution 필터의 형태 때문에 객체의 형태에 따라 유동적으로 대응하지 못했다. 본 논문에서는 이를 보완하고자 Deformable Convolution과 셀프어텐션(Self-attention) 구조기반 어텐션 모듈을 사용한 의미론적 분할 모델을 제안한다.

Guidelines for Manufacturing and Application of Organoids: Brain

  • Taehwan Kwak;Si-Hyung Park;Siyoung Lee;Yujeong Shin;Ki-Jun Yoon;Seung-Woo Cho;Jong-Chan Park;Seung-Ho Yang;Heeyeong Cho;Heh-In Im;Sun-Ju Ahn;Woong Sun;Ji Hun Yang
    • International Journal of Stem Cells
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    • v.17 no.2
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    • pp.158-181
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    • 2024
  • This study offers a comprehensive overview of brain organoids for researchers. It combines expert opinions with technical summaries on organoid definitions, characteristics, culture methods, and quality control. This approach aims to enhance the utilization of brain organoids in research. Brain organoids, as three-dimensional human cell models mimicking the nervous system, hold immense promise for studying the human brain. They offer advantages over traditional methods, replicating anatomical structures, physiological features, and complex neuronal networks. Additionally, brain organoids can model nervous system development and interactions between cell types and the microenvironment. By providing a foundation for utilizing the most human-relevant tissue models, this work empowers researchers to overcome limitations of two-dimensional cultures and conduct advanced disease modeling research.

A New Approach Method of Measuring Abdominal Pressure for Urodynamic Monitoring System (요역동학 측정시스템을 위한 새로운 복압측정 기법)

  • Seo, Jeong-Hwan;Kim, Keo-Sik;An, Yang-Su;Kim, Kyeong-Seop;Song, Chul-Gyu
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.6
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    • pp.1170-1176
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    • 2007
  • The conventional urodynamic monitoring is fulfilled by artificially filling a bladder with saline. Generally. it is difficult to evaluate the physiological functions of the storage and voiding of a bladder. With this aim, we constructed an ambulatory urodynamic monitoring (AUM) system and proposed a novel method estimating abdominal pressure by measuring bio-impedance variations. Our system was clinically evaluated for 10 patients. It turned out to be that as the intensity of the abdomen contraction increased, the amplitude of bio-impedance signal and the RMS value of EMG increased more as compared to those who observed during the rest mode. Also, we determined the optimum electrode pair for estimating the abdominal pressure using bio-impedance method and consequently compared with the conventional methods. Because impedance changes differ from a weight, a height, contractile force, volume of muscle and blood other or whatever of individuals, it was quantified in terms of impedance change, correlation coefficient and SNR Our results showed the optimum electrode pair (1,9) which could detect impedance changes due to the increase of the intensity in the abdominal pressure. The correlation coefficient and quadratic function between the RMS values of EMG and the impedance changes were 0.87 and $y=0.0014x^2+0.0620x+0.6958$, respectively. Thus, our system demonstrated that the abdominal pressure could be measured noninvasively and conveniently by simply estimating bio-impedance values. We propose that this optimum electrode configuration would be useful for the future studies involving the handy measurements of abdominal pressure with our suggested ambulatory urodynamics monitoring system.

Novel 10 GHz Bio-Radar System Based on Frequency Multiplier and Phase-Locked Loop (주파수 체배기와 PLL을 이용한 10 GHz 생체 신호 레이더 시스템)

  • Myoung, Seong-Sik;An, Yong-Jun;Moon, Jun-Ho;Jang, Byung-Jun;Yook, Jong-Gwan
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.21 no.2
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    • pp.208-217
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    • 2010
  • This paper presents a novel 10 GHz bio-radar system based on a frequency multiplier and phase-locked loop(PLL) for non-contact measurement of heartbeat and respiration rates. In this paper, a 2.5 GHz voltage controlled oscillator (VCO) with PLL is employed to as a frequency synthesizer, and 10 GHz continuous wave(CW) signal is generated by using frequency multiplier from 2.5 GHz signal. This paper also presents the noise characteristic of the proposed system. As a result, a better performance and economical frequency synthesizer can be achieved with the proposed bio-radar system. The experimental results shows excellent bio-signal measurement up to 100 cm without any additional digital signal processing(DSP), and the proposed system is validated.

A Novel Bioassay System for Screening of Compounds Affecting Anthocyanin Biosynthesis Pathway in White Corn Leaf Segment (백화옥수수 잎절편을 이용한 안토시아닌 생합성 조절제 탐색용 신규 검정법 확립)

  • Kim, Jin-Seog;Lee, Byung-Hoi;Lee, Jung-Ae;Oh, Kwang-Hoon;Cho, Kwang-Yun
    • Journal of Plant Biotechnology
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    • v.30 no.2
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    • pp.207-214
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    • 2003
  • This study was carried out to establish a novel bioassay system for screening of compounds affecting aromatic amino acid or anthocyanin biosynthesis through investigating a degree of sucrose-induced anthocyanin formation such as size of plant material, buffer conditions, light intensity and irradiated duration, incubation temp., etc were determined and standard procedure (suitable experimental condition) was set up as follows. The second leaf blade of white corn seeding induced by fluridone treatment were segmented into a size of 5${\times}$5 min. The segments were floated on the solution of 1% sucrose in 1.0mM MES buffer (pH6.0∼6.5) and incubated at 26$^{\circ}C$ for 2days under the continuous light condition(70∼100$\mu$mol m$^{-2}$ s$^{-1}$ ). Anthocyanin in the purpled tissues was extracted with methanol containing 1% HCl and the optical density of the clear supematants was determined at 528mm. Influences of some chemicals were tested using this system. Glyphosate, 5-enolpyruvylshikimate 3-phosphate synthase inhibitor, showed most sensitive response with I$_{50}$ value at 3.3$\mu$M. Dicyclohexylcarbodiimide(DCCD) and parachloromercuribenzenesulfonic acid(PCMBS) had a relatively strong ingibition with I50 value at 7.1$\mu$M and 10.2$\mu$M, respectively. These results show that sucrose-induced anthocyanin formation in white com leaf segment provide a very simple and rapid system for searching new compounds affecting aromatic amino acid or anteocyanin biosynthesis by screening at less than 10$\mu$M.

Real time remote management for home network system using bio-physical sensor (생체 센서 시스템을 이용한 실시간 원격 홈 네트워크 시스템)

  • Kim, Jeong-Lae
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.1
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    • pp.117-124
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    • 2011
  • This study was realized the home network system for home care by bio-physical sensor system, to convey for the remote physical signal. The composition condition has four functions of displacement point for a Vision, Somatosensory, Vestibular and CNS that the basic measurement used to a Heart Rate, Temperature, Weight. Physical signal are decided to search a max and min point with adjustment of 0.01 unit in the reference level. There were checked physical condition of body balance to compounded a physical neuroceptor of sensory organ for the measurement such as a Vision, Somatosensory, Vestibular, CNS, BMI. There are to check a health care condition through a combination of physical organ with a posturography of a exercise. The service of home network system can be used to support health care management system through health assistants in health care center and central health care system. It was expected to monitor a physical parameter for the remote control health management system.

AUTOMATIC GUIDANCE SYSTEM FOR COMBINE USING DGPS AND GYRO SENSOR

  • Park, C. H.;Kim, J. M.;M. J. NahmGung
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 2000.11b
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    • pp.333-343
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    • 2000
  • An automatic guidance system for combine was designed to harvest paddy rice by following a predetermined path. The automatic guidance system consisted of DGPS to locate position of combine, a gyro sensor system to measure heading angle, ultrasonic sensors to detect obstacles, a hydraulic system, microcomputer as a controller, and I/O interface system. Hydraulic cylinders and valves were installed to control movement of the combine. The heading angle and the position of the combine, and ultrasonic measurements from edge were used as the inputs of the controller. The operating position of hydraulic cylinder was determined as output of the controller. The automatic guidance system was evaluated at the 45-m straight path by changing the posture of the combine. The average RMS errors were 14.0 cm without offset and 15.0 cm with 1-m offset. The DGPS provided accurate position information within the limited error to guide the combine in the field. The results showed that the automatic guidance system could guide the combine autonomously in the paddy field when the posture of the combine was changed.

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A New Selection System for Pepper Regeneration by Mannose

  • Kim, Joo-Yean;Min Jung;Kim, Hyo-Soon;Lee, Yun-Hee;Park, Soon-Ho;Lim, Yong-Pyo;Min, Byung-Whan;Yang, Seung-Gyun;Harn, Chee-Hark
    • Journal of Plant Biotechnology
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    • v.4 no.3
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    • pp.129-134
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    • 2002
  • We report the development of a new selection system for the transformation of pepper plants by mannose. In order to achieve this, we first tested several factors related to regeneration conditions. Among the 30 inbred lines examined, line P9l5 was able to generate shoots at the highest rate from both cotyledons and hyporotyls in MS media. A dosage curve for optimizing the selection conditions was established by mixing mannose (range 0-50 g/L) and sucrose (range 0-30 g/L). The least selection pressure on shoot formation was created by a mixture of sucrose and mannose at 20 g/L and 15 g/L, respectively, and the threshold for ultimate tissue death was 50 g/L of mannose irrespective of the sucrose concentration. However, we found that mannose itself was not the sole inhibitor of pepper shoot development. High concentrations of sucrose (30 g/L) contributed additively to the inhibition of shoot formation at higher mannose concentrations. Genotype preference is a major factor that enhances regeneration ability in mannose media, as was observed in MS media. P9l5 and P410 line had high regeneration rates under mannose selection conditions in the presence of Agrobacterium infection. Different virulence levels of Agrobacterium strains did change the regeneration rates, probably due to interaction with the specificities of the inbred lines. Taken together, P9l5 offers the best pepper inbred line for transformation and we recommend a selection condition of 20 g/L of sucrose and 15 g/L or more of mannose up to 50 g/L in media.

FDM 3D Printing of Environmental Friendly and High Strength Bio-based PC Filaments for Baby Toys

  • Park, Seong Je;Lee, Ji Eun;Park, Jean Ho;Lyu, Min-Young;Park, Keun;Koo, Myung Sool;Jin, Sun Chul;Kim, Ki Yong;Son, Yong
    • Elastomers and Composites
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    • v.52 no.2
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    • pp.99-104
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    • 2017
  • Due to the depletion of fossil oil and the increasing oil price, bio-plastic is currently topical. Bio-based plastics are synthesized from plant resources, unlike conventional petroleum-based counterparts. Therefore, the former minimizes global warming and reduces carbon dioxide emission. Fossil polycarbonate (PC)has good mechanical and optical properties, but its synthesis requires bisphenol-A and phosgene gas, which are toxic to humans. To address these problems, the fused deposition 3D printing process (hereafter, FDM) is studied using environmentally-friendly and high-strength bio-based PC. A comparisonof the environmental impact and tensile strength of fossil PC versus bio-based PC is presented herein, demonstrating that bio-based PC is more environmentally-friendly with higher tensile strength than fossil PC. The advantages of bio-based PC are applied in the FDM process for the fabrication of environmentally-friendly baby toys.