• Title/Summary/Keyword: Bio-material

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Studies on the Antioxidant and Whitening Effects of Cheongyang Pepper based on a Bibliometric Approach

  • Eunsoo Sohn;Hyo Jin Kim;Chang Woo Ha;Sohee Jang;Jung Hun Choi;Sung Hyeok Kim;Tae-Seong Lee;Eun-Hwa Sohn
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2023.04a
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    • pp.41-41
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    • 2023
  • Red pepper (Capsicum annuum L.) is one of the most consumed vegetable worldwide. In this study, we tried to suggest the possibility of Cheongyang pepper as a functional cosmetic material by identifying the physiological activity, especially antioxidant and whitening effects of Cheongyang pepper through bibliometric analysis and experimental studies. A bibliometric analysis was performed through co-word analysis of 8,892 papers retrieved from SCOPUS. 4 research fields were obtained by cluster mapping from VOSviewer software, among which we noted the antioxidant activity of extracts from Capsicum annum L.. Phenol as a useful ingredient of Cheongyang pepper was analyzed using HPLC (high-performance liquid chromatography). Antioxidant and whitening effects were evaluated by measuring DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity, hydrogen peroxide scavenging activity, and tyrosinase inhibitory activity. Cheongyang pepper extract showed contents of 0.106 ± 0.01 and 0.105 ± 0.02 mg/g, respectively, in the order of gallic acid and protocatechuic acid. The extract exhibited 56.95% DPPH scavenging activity and 43.97% hydrogen peroxide scavenging activity at a concentration of 1,000 ㎍/ml. In addition, 1,000 ㎍/ml of the extract inhibited tyrosinase activity by 52.44% and 42.61%, respectively in a whitening efficacy test using L-tyrosine and L-DOPA (L-3,4- dihydroxyphenylalanine) as substrates. These results suggest that Cheongyang pepper extract and its active ingredients have antioxidant and whitening effects, and the possibility of future development as a whitening functional cosmetic material.

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Biochemical Characteristics of a Bacteria (Bacillus pseudomycoides) Alanine Racemase Expressed in Escherichia coli (Bacillus pseudomycoides로 부터 분리된 alanine racemase 유전자의 발현 및 생화학 특성)

  • Kang, Han-Chul;Kim, Na-Hyun;Jeong, Yu-Jeong;Yoon, Sang-Hong;Lee, Chang-Muk
    • Journal of Applied Biological Chemistry
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    • v.53 no.3
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    • pp.132-138
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    • 2010
  • A gene encoding a putative alanine racemase in B. pseudomycoides was cloned and expressed in Escherichia coli BL21(DE3) using a pET-21 vector harbouring 6xHistidine tag. Affinity purification of the recombinant alanine racemase with a nickel resin resulted in one band by SDS-PAGE analysis. The purified enzyme showed a molecular weight of 46 kDa. The enzyme was the most active toward L-alanine and secondly D-alanine, implying that the enzyme is an alanine racemase. D-cysteine significantly inhibited the enzyme activity and also L-cysteine to a lesser extent. The enzyme was considerably activated by addition of pyridoxal-5'-phosphate (PLP), showing that 73% increase in activity was observed at 0.3 mM, compared to control. The enzyme was the most active at pH 9.0 and more stable at alkaline pHs than acidic pHs.

Diversity and Chemical Defense Role of Culturable Non-Actinobacterial Bacteria Isolated from the South China Sea Gorgonians

  • Jiang, Peng;Zhang, Xiaoyong;Xu, Xinya;He, Fei;Qi, Shuhua
    • Journal of Microbiology and Biotechnology
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    • v.23 no.4
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    • pp.437-443
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    • 2013
  • The diversity of culturable non-actinobacterial (NA) bacteria associated with four species of South China Sea gorgonians was investigated using culture-dependent methods followed by analysis of the bacterial 16S rDNA sequence. A total of 76 bacterial isolates were recovered and identified, which belonged to 21 species of 7 genera, and Bacillus was the most diverse genus. Fifty-one percent of the 76 isolates displayed antibacterial activities, and most of them belonged to the Bacillus genus. From the culture broth of gorgonian-associated Bacillus methylotrophicus SCSGAB0092 isolated from gorgonian Melitodes squamata, 11 antimicrobial lipopeptides including seven surfactins and four iturins were obtained. These results imply that Bacillus strains associated with gorgonians play roles in coral defense mechanisms through producing antimicrobial substances. This study, for the first time, compares the diversity of culturable NA bacterial communities among four species of South China Sea gorgonians and investigates the secondary metabolites of gorgonian-associated B. methylotrophicus SCSGAB0092.

The Korean Ginseng Root Transcriptome : Analysis of 6816 Expressed Sequence Tags

  • In, Jun-Gyo;Lee, Bum-Soo;Yang, Deok-Chun
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2003.04a
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    • pp.65-66
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    • 2003
  • Korean ginseng (Panax ginseng C. A. Meyer) is an representative medicinal herb. It is classified as an adaptogen, helping the body to adapt to stress, improving stamina and concentration, and providing a normalizing and restorative effect. However, cultivation and breeding of the plant is very difficult because it requires at least 4-year cultivation from seed germination to root harvest.(중략)

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Octacalcium phosphate, a promising bone substitute material: a narrative review

  • Jooseong Kim;Sukyoung Kim;Inhwan Song
    • Journal of Yeungnam Medical Science
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    • v.41 no.1
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    • pp.4-12
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    • 2024
  • Biomaterials have been used to supplement and restore function and structure by replacing or restoring parts of damaged tissues and organs. In ancient times, the medical use of biomaterials was limited owing to infection during surgery and poor surgical techniques. However, in modern times, the medical applications of biomaterials are diversifying owing to great developments in material science and medical technology. In this paper, we introduce biomaterials, focusing on calcium phosphate ceramics, including octacalcium phosphate, which has recently attracted attention as a bone graft material.

Bio-Piezoelectric Generator with Silk Fibroin Films Prepared by Dip-Coating Method (딥코팅에 의한 실크 피브로인막으로 제조한 바이오 압전발전기)

  • Kim, Min-Soo;Park, Sang-Shik
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.34 no.6
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    • pp.487-494
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    • 2021
  • Piezoelectric generators use direct piezoelectric effects that convert mechanical energy into electrical energy. Many studies were attempted to fabricate piezoelectric generators using piezoelectrics such as ZnO, PZT, PVDF. However, these various inorganic/organic piezoelectric materials are not suitable for bio-implantable devices due to problems such as brittleness, toxicity, bio-incompatibility, bio-degradation. Thus, in this paper, piezoelectric generators were prepared using a silk fibroin film which is bio-compatible by dip-coating method. The silk fibroin films are a mixed state of silk I and silk II having stable β-sheet type structures and shows the d33 value of 8~10 pC/N. There was a difference in output voltages according to the thickness. The silk fibroin generators, coated 10 times and 20 times, revealed the power density of 16.07 μW/cm2 and 35.31 μW/cm2 using pushing tester, respectively. The silk fibroin generators are sensitive to various pressure levels, which may arise from body motions such as finger tapping, foot pressing, wrist shaking, etc. The silk fibroin piezoelectric generators with bio-compatibility shows the applicability as a low-power implantable piezoelectric generator, healthcare monitoring service, and biotherapy devices.

Study of Non Pressure and Pressure Foam of Bio-based Polymer Containing Blend (바이오 기반 폴리머가 포함된 블렌드의 상압 및 가압 발포 연구)

  • Dong-Hun Han;Young-Min Kim;Danbi Lee;Seongho Son;Geon-hee Seo;Hanseong Kim
    • Composites Research
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    • v.36 no.5
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    • pp.297-302
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    • 2023
  • There are several methods for shaping foams, but the most commonly used methods involve the use of resin mixed with a foaming agent, which is then foamed under high temperature and pressure in the case of compression foaming, or foamed under high temperature without applying pressure in the case of atmospheric foaming. The polymers used for foaming require design and analysis of optimal foaming conditions in order to achieve foaming under ambient pressure. Environmentally friendly bio-based polymers face challenges when it comes to foaming on their own, which has led to ongoing research in blending them with resins capable of traditional foam production. This study investigates changes in the characteristics of bio-based polymer-EVA blend foams based on variations in the content of bio-based polymers and explores the optimal foaming conditions according to crosslinking. The correlation between foaming characteristics and mechanical properties of the foams was examined. Through this research, we gained insights into how the content of bio-based polymers affects the properties of foams containing bio-based polymers and identified differences between ambient pressure and high-pressure foaming processes. Additionally, the feasibility of commercializing bio-based polymer-EVA composite foams was confirmed.

Curing behavior of Photo-Curable Materials by Photo-Shrinkage Test (광원 경화형 소재의 수축률평가를 통한 광경화 거동 평가)

  • Park, Ji-Won;Bae, Kyung-Yul;Kim, Pan-Seok;Lim, Dong-Hyuk;Kim, Hyun-Joong;Cho, Jin-Ku;Kim, Baek-Jin;Lee, Sang-Hyeup
    • Journal of Adhesion and Interface
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    • v.11 no.2
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    • pp.57-62
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    • 2010
  • Photo-curable material can be crosslinked among molecules by light source such as UV and visible light materials. Material properties are controlled by crosslink reaction. Shrinkage is occured during the curing reaction of material structure. Phenomenon of shrinkage stress occurs inside the product and reduce the stability of the product causes problems. Heat shrink the evaluation of the phenomenon has been formalized. But the evaluation of photo shrink is not enough. In this experiment, real-time contract with shrinkage tester phenomena and analysis degree of shrinkage of the material differences. According to the research, experimental results and theoretical analysis of the results were big differences. Shrinkage, especially for a number of different functional groups that were very different theory. These differences are occurred by the molecular structure different and not enough reaction.