• Title/Summary/Keyword: Bio-impedance

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Association of carotid atherosclerosis and obesity in type 2 diabetic patients (제2형 당뇨병 환자에서 비만과 경동맥 경화증과의 관계)

  • Gang, Se-Hun;Kim, Gyeong-Min;Jo, Dong-Hyeok;Gang, Ho-Cheol;Jeong, Dong-Jin;Jeong, Min-Yeong
    • Journal of Korea Association of Health Promotion
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    • v.4 no.1
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    • pp.12-27
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    • 2006
  • "본 논문은 대한내과학회지 2006년 제70권 제3호에 실렸던 논문으로 대한내과학회 편집위원회의 승인을 득하고 본 협회지에 게재함. Background : Diabetes mellitus is a major independent risk factor for atherosclerosis. In recent years non-invasive high resolution B-mode ultrasound methods have been developed to measure the intima-media thickness(IMT) of the carotid artery as an indicator for early atherosclerosis. Itis known that obesity plays a role in the development of type 2 diabetes and cardiovascular disease, and it has also been reported that not only the amount but also the distribution of body fat is important. This study investigated the relationship between obesity and the development of carotid atherosclerosis in type 2 diabetic patients. Methods: Carotid IMT was measured by ultrasound B-mode imaging in 144 patients with type 2diabetes mellitus. All subjects underwent assessment for the degree and distribution of obesity, the presence of coronary artery disease risk factors, and the presence of diabetic complications. Resuts: Carotid IMT was increased in the abdominal obese group defined by waist circurference. However, there was no significant difference in carotid TMT between the non-obese group and obese group as defined by body mass index, waist to hip ratio, and total body fat percent measured by bio electrical impedance analysis. There were positive correlations between carotid IMT and age, duration of diabetes, systolic blood pressure, and waist circumference. Multiple linear regression analysis revealed the variable that interacted independently with carotid IMT was age in type 2 diabetic patients. Carotid IMT was significantly increased in type 2 diabetic patients with macrovascular complications and microvascvlar complications .Conclusion: This study suggested that abdominal obesity rather than general obesity was associated with carotid atherosclerosis reflected by increment of carotid IMT in type 2 diabetic subjects.

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Changes in Nutritional Status of General Medical Patients During Hospitalization (내과 환자의 입원후 영양상태 변화 연구)

  • 양영희;최스미;김은경
    • Journal of Korean Academy of Nursing
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    • v.27 no.1
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    • pp.49-60
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    • 1997
  • The purpose of this study was to determine the incidence of malnutrition among patients on admission to hospital, to monitor changes in their nutritional status during hospitalization, and to determine the factors which might affect changes in nutritional status. The subjects for the study were patients who were admitted to general medicine for more than one week. Patients suffering from cardiovascular. renal disease, or dehydration were excluded. Nutritional assessment of the patients was performed on admission and nutritional status was reassessed one week and two weeks after admission. The nutritional assessment tool consisted of subjective history taking and anthropometric measurements. Biochemical measurements were performed only on admission. For anthropometric assessment : patients' body weight, subcutaneous skinfolds thickness, % of body fat, body mass index, and lean body mass were measured using caliper or Bio impedance Analyzer. Factors which might influence current nutritional status, like dietary intake, anorexia, nausea, vomiting, diarrhea, sleep disturbance, and number of days of NPO for diagnostic examinations were analyzed. The results are as follows : 1. Of the 59 patients who were studied, 61% were male and 39% female. The nutritional status of all of the 59 subjects was reassessed one week after admission, but it was only done for 22 subjects at two weeks. 2. The anthropometric measurements. including weight body mass index, lean body mass, body fat. and skin fold thickness. were all significantly decreased at one week after admission compared to the values at admission. On the other hand, two weeks after admission, only body weight and abdominal skinfolds thickness were decreased. 3. The subjects reported anorexia for an average of two days, sleep disturbance for two days, and no food intake due to diagnostic test for one day. In the second week of hospitalization, almost none of the patients complained of gastrointestinal symptoms or sleep disturbance except anorexia. Food consumption which was measured based on rice intake was 60% of the food served during the first week of hospitalization, and 66% during the second week of hospitalization. 4. There was no correlation between the subjective nutritional assessment and anthropometric assessment. 5. There was no statistical significance in anthropometric measurements among the patients with various diseases whereas sleep disturbance and no food intake due to various diagnostic test was prominent in patients with gastrointestinal diseases.

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Conductivity Imaging of a Canine Head using a 3T MREIT System with a Carbon-Hydrogel Electrode: Postmortem Experiment (3T MREIT 시스템을 이용한 실험견 사체의 두부 도전율 영상)

  • Jeong, Woo-Chul;Kim, Young-Tae;Minhas, Atul S.;Kim, Hyung-Joong;Lee, Tae-Hwi;Kang, Byeong-Teck;Park, Hee-Myung;Woo, Eung-Je
    • Journal of Biomedical Engineering Research
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    • v.30 no.2
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    • pp.179-184
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    • 2009
  • Magnetic Resonance Electrical Impedance Tomography (MREIT) is a new bio-imaging modality providing cross-sectional conductivity images from measurements of internal magnetic flux densities produced by externally injected currents. Recent MREIT studies demonstrated successful conductivity image reconstructions of postmortem and in vivo canine brain. However, the whole head imaging was not achieved due to technical issues related with electrodes and noise in measured magnetic flux density data. In this study, we used a new carbon-hydrogel electrode with a large contact area and injected 30 mA imaging current through a canine head. Using a 3T MREIT system, we performed a postmortem canine experiment and produced high-resolution conductivity images of the entire canine head. Collecting magnetic flux density data inside the head subject to multiple injection currents, we reconstructed cross-sectional conductivity images using the harmonic $B_z$ algorithm. The conductivity images of the canine head show a good contrast not only inside the brain region including white and gray matter but also outside the brain region including the skull, temporalis muscle, mandible, lingualis proprius muscle, and masseter muscle.

An ECG monitoring system using a conductive thread-based wearable antenna (전도성 섬유 웨어러블 안테나를 기반으로 한 심전도 모니터링 시스템 설계)

  • Chung, Jae-Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.5
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    • pp.10-15
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    • 2017
  • Research interest has strongly focused on developing a method for effectively transmitting bio-signals over a distance using a wireless wearable device. In this paper, we describe a procedure for the design and fabrication of a wearable antenna based on embroidering conductive threads to clothing capable of transmitting electrocardiogram signals. 3D electromagnetic simulation software and embroidery software were used to design and fabricate the conductive thread-based antenna, respectively. The measurement results show that the reflection coefficient of the fabricated antenna prototype exhibits excellent antenna impedance matching characteristics of less than -10dB in the Zigbee 2.4GHz frequency band. We also verified that the electrocardiogram data could be effectively received and monitored in real-time by a receiver 220m away from the transmitter.

Body Weight Control, Attitudes, Lifestyle and Dietary Habits in Elementary School Students According to the Obesity Index (초등학생의 비만도에 따른 체중 조절과 건강 관련 생활, 식습관)

  • Park, Yoon-Hee;Park, Eun-Sook
    • Journal of the East Asian Society of Dietary Life
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    • v.20 no.1
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    • pp.175-186
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    • 2010
  • This study was conducted to investigate the body weight control, attitudes, lifestyles and dietary habits according to the obesity index of elementary school students. This study utilized questionnaires and body composition measurements collected with a bio- electrical impedance analyzer(Inbody 4.0). Specifically, differences between the underweight group, normal group, and overweight group were tested by a $x^2$-test or ANOVA and Duncan's multiple range test. The subjects consisted of 571 elementary school students residing in Chonbuk Province. The average age, height, weight, and BMI of the male subjects was 11.5 years, 150.0 cm, 45.2 kg and $20.0\;kg/m^2$, respectively. The average age, height, weight, and BMI of the female subjects was 11.5 years, 152.2 cm, 46.1 kg and $19.8\;kg/m^2$, respectively. Twenty percent of the subjects were in the underweight group, 52.2% were in the normal weight group, and 27.8% were in the overweight group according to the Korean Pediatrics Society standards. A total of 50.2% of the subjects were dissatisfied with their body weight, while 36.8% of underweight, 42.3% of normal weight, and 81.1% of overweight subjects were dissatisfied with their weight. Fifty two percent of the subjects had attempted to reduce their body weight, including 50% of the normal weight group. The main reason for wanting to reduce body weight was to maintain health. The percentage of subjects who had received body weight control education was 41.3%, but 77.6% of the subjects thought it was necessary. Poor time management, lack of physical activity, portion size of meals, unbalanced diet, frequent consumption of convenience foods, and frequent snacking all affected the obesity index. Overall, the results of this study indicate that it is necessary to develop weight control programs for all elementary school students who are underweight, normal weight, and overweight.

Development of Sasang Type Diagnostic Test with Neural Network (신경망을 사용한 사상체질 진단검사 개발 연구)

  • Chae, Han;Hwang, Sang-Moon;Eom, Il-Kyu;Kim, Byoung-Chul;Kim, Young-In;Kim, Byung-Joo;Kwon, Young-Kyu
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.4
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    • pp.765-771
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    • 2009
  • The medical informatics for clustering Sasang types with collected clinical data is important for the personalized medicine, but it has not been thoroughly studied yet. The purpose of this study was to examine the usefulness of neural network data mining algorithm for traditional Korean medicine. We used Kohonen neural network, the Self-Organizing Map (SOM), for the analysis of biomedical information following data pre-processing and calculated the validity index as percentage correctly predicted and type-specific sensitivity. We can extract 12 data fields from 30 after data pre-processing with correlation analysis and latent functional relationship analysis. The profile of Myers-Briggs Type Inidcator and Bio-Impedance Analysis data which are clustered with SOM was similar to that of original measurements. The percentage correctly predicted was 56%, and sensitivity for So-Yang, Tae-Eum and So-Eum type were 56%, 48%, and 61%, respectively. This study showed that the neural network algorithm for clustering Sasang types based on clinical data is useful for the sasang type diagnostic test itself. We discussed the importance of data pre-processing and clustering algorithm for the validity of medical devices in traditional Korean medicine.

Corrosion Charateristics of PEO-treated Ti-6Al-4V Alloy in Solution Containing Si and Mg Ions

  • Park, Seon-Yeong;Choe, Han-Cheol
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2017.05a
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    • pp.153-153
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    • 2017
  • The application of the coating supports the mechanical characteristics of the implant, and various materials and coatings are currently being used in the implant in a way to accelerate adhesion. Especially, plasma electrolytic oxidation (PEO) coating has been proposed continually with good surface treatment of titanium alloys. Also, the PEO process can incorporate Ca and P ions on the titanium surface through variables varied factor. PEO process for bioactive surface has carried out in electrolytes containing Ca and P ions. Natural bone is composed of mineral elements such as Mg, Si, Zn, Sr, and Mn, etc. Especially, Mg and Si of these elements play role in bone formation and growth after clinical implantation of bio-implants. In this study, corrosion charateristics of PEO-treated Ti-6Al-4V alloy in solution containing Si and Mg ions has been investigated using several experimental techniques. The PEO-treated surfaces were identified by X-ray diffraction, using a diffractometer (XRD, Philips X' pert PRO, Netherlands) with Cu $K{\alpha}$ radiation. The morphology was observed by field-emission scanning electron microscopy (FE-SEM, Hitachi 4800, Japan) and energy-dispersive X-ray spectroscopy (EDX, Oxford ISIS 310, England). The potentiodynamic polarization and AC impedance tests for electrochemical degradations were carried out in 0.9% NaCl solution at similar body temperature using a potentiostat with a scan rate of 1.67mV/s and potential range from -1500mV to + 2000mV.

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The Effect of A-3826G Polymorphism of Uncoupling Protein-Ion Visceral Fat Area in Overweight Korean Women

  • Kim, Kil-Soo;Cha, Min-Ho;Kim, Jong-Yeol;Shin, Seung-Uoo;Yoon, Yoo-Sik
    • Preventive Nutrition and Food Science
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    • v.10 no.3
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    • pp.279-284
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    • 2005
  • Uncoupling protein-1 (UCP-1) plays a major role in thermogenesis, and has been implicated in the pathogenesis of obesity and metabolic disorders. The aim of this study was to estimate the effects of A-3826G polymorphism of UCP-1 gene on body fat distribution. Two hundred forty eight Korean female overweight subjects with BMI more than 25 kgfm2 participated in this study. The areas of abdominal subcutaneous and visceral fat of all subjects were measured from computed tomography cross sectional pictures of the umbilical region. Subcutaneous fat areas of upper and lower thigh were also measured. Body composition was measured by bio-impedance analysis, and serum concentrations of biochemical parameters, such as glucose, triglyceride, cholesterol etc, were also measured. Genotype of UCP-1 was analyzed by polymerase chain reaction (PCR) restriction fragment length polymorphism (RFLP) method. The frequencies of UCP-1 genotypes were AA type; $27.8\%,\;AG\;type;\;51.2\%\;and\;GG\;type;\;21.0\%,$ and the frequency of G allele was 0.47. Body weight, BMI, WHR, SBP, DBP and body compositions were not significantly different by UCP-1 genotype. Abdominal visceral fat area was significantly higher in AG and GG type compared with AA type (p=0.009), but subcutaneous fat areas were not significantly different by UCP-1 genotype. Among biochemical parameters, LDL cholesterol level was significantly higher in GG type compared with AA and AG types (p=0.033). Among all subjects, 121 subjects finished 1 month weight loss program containing hypocaloric diet and exercise. The reduction of body weight and BMI were lower in GG type compared with AA/AG type even though statistical significances were not found (p > 0.05). These results suggest that UCP-1 genotype has a significant effect on visceral fat accumulation among Korean female overweight subjects with BMI more than $25\;kg/m^2$.

The Correlation between HTMA(Hair Tissue Mineral Analysis) Results and Obese Degree (모발미네랄분석결과와 비만도의 상관성)

  • Song, Jae-Chol;Lee, Jae-Sung;Lee, Kyung-Hee;Shin, Hyun-Taeg
    • Journal of Korean Medicine for Obesity Research
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    • v.4 no.1
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    • pp.67-80
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    • 2004
  • Objectives: Obesity is a growing epidemic with subsequent health consequences leading not only to reduced quality of life but also to increased medical costs. Recently nutritional balances are emphasized in the field of obesity, and especially maintaining proper equilibriums of minerals. The correlation of minerals obtained from the method of HTMA(Hair Tissue Mineral Analysis) with obese degree has not been studied in Korea yet. We studied any significant difference of mineral concentrations and components according to the obese degree. Methods: 78 subjects were analyzed who visited Garosero clinic of oriental medicine to lose their weight from June to November 2004. We used BMI(Body Mass Index), PBF(Percent Body Fat), WHR(Waist-Hip Ratio) and abdominal circumference obtained by bio-electrical impedance analysis as an obese degree. And we analyzed correlation with mineral concentrations and ratios obtained from HTMA. Results & Conclusion: 1. Na, K, Zn, Se had significant correlation with obese degree in case of nutritional minerals from HTMA. Especially, K had high significance. 2. Toxic minerals from HTMA had no significance with obese degree. 3. Rb had significant correlation with obese degree in case of additional minerals from HTMA. 4. Among important ratios from HTMA, Na/K had significant correlation with obese degree, but Ca/K had correlation except PBF, and Na/Mg had correlation except WHR. 5. Among toxic ratios from HTMA, Se/Hg had significant correlation with obese degree, but S/Hg had correlation except BMI. 6. Na, K, Zn, Rb, Na/K, Ca/K had significant differences between obesity groups classfied by BMI. Ob II group had sinificant difference from NW group in cases of K, Zn, Rb, Na/K, and Ob II group had sinificant difference from OW group in case of Ca/K.

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Development of shock wave induced microparticle acceleration system based on laser ablation and its application on drug delivery (충격파를 이용한 레이저 어블레이션 기반의 마이크로 입자 가속 시스템 개발 및 약물전달 응용)

  • Choi, Ji-Hee;Gojani, Ardian B.;Lee, Hyun-Hee;Yoh, Jai-Ick
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.36 no.6
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    • pp.587-593
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    • 2008
  • Transdermal and topical drug delivery with minimal tissue damage has been an area of vigorous research for years. Our research team has initiated the development of an effective method for delivering drug particles across the skin (transdermal) for systemic circulation, and to localized (topical) areas. The device consists of a laser ablation based micro-particle acceleration system that can be integrated with endoscopic surgical techniques. We have successfully delivered 3μm size cobalt particles into gelatin models that represent soft tissue with remarkable penetration depth.