• Title/Summary/Keyword: Bio-glass

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Physical and Chemical Characteristics of Oilsands Bitumen Using Vacuum Distillation (감압증류장치를 이용한 Oilsands Bitumen의 물리화학적 특성 연구)

  • Kim, Kyoung-Hoon;Jeon, Sang-Goo;Roh, Nam-Sun;Kim, Kwang-Ho;Shin, Dae-Hyun;Park, Hyo-Nam;Han, Myung-Wan
    • Journal of Energy Engineering
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    • v.17 no.1
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    • pp.15-22
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    • 2008
  • This study was carried out to investigate physical and chemical characteristics of the distillates and residue of Athabasca oilsand bitumen obtained from Canada, using a vacuum distillation unit. The distillates and residue produced from the vacuum distillation were characterized through atomic analysis, SARA analysis, and measurement of boiling point distribution, molecular weight, and API gravity. The vacuum distillation equipment consisted of a 6-litter volume vessel, a glass-packed column, a condenser, a reflux device, a flask fer collecting distillates, and a temperature controller. The cutting of distillates was performed with four steps under the condition of full vacuum and maximum temperature of $320^{\circ}C$. The results showed that the sulfur amount and average molecular weight of the distillates were significantly reduced compared to those of oilsand bitumen. As the cutting temperature increased, the hydrogen amount decreased but the sulfur amount and average molecular weight increased in the distillates.

Metal Surface Coating Using Electrospray of Biodegradable Polymers and $\alpha$-Lipoic Acid Release Behavior for Drug-Eluting Stents (생분해성 고분자의 전기분사를 이용한 약물방출 스텐트용 금속표면 코팅 및 ALA방출 거동)

  • Kim, Dong-Min;Lee, Bong-Soo;Park, Cheol-Ho;Park, Kwi-Deok;Son, Tae-Il;Jeong, Myeong-Ho;Han, Dong-Keun
    • Polymer(Korea)
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    • v.34 no.2
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    • pp.178-183
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    • 2010
  • Medical metal stents inserted to patients with a cardiovascular disease associated with coronary artery system have relatively increased the survival rate. The development of new stents is, however, urgently required due to restenosis and late thrombosis generated in metal stents. To solve these problems, the biodegradable polymers such as poly(lactide-co-glycolide) (PLGA), poly(L-lactide)(PLLA), and poly ($\varepsilon$-caprolactone)(PCL) were mixed with alpha lipoic acid (ALA), which is well known to inhibit the proliferation of neointimal hyperplasia. Subsequently, the ALA-loaded polymers were coated on stainless steel by electrospray. The drug-eluting behaviors from the coated polymers were investigated according to kinds and concentrations of polymers, spray rates, and kinds of solvents. The drug-eluting rate from PCL with the lowest glass transition temperature was the fastest among three polymers and followed by PLGA and PLLA. The surface roughness increased as the spray rate was increased and also the drug-eluting rate was affected by kinds of solvents with different boiling point. It is expected that drug-eluting stent (DES) coated with ALA-loaded polymers can be applied practically for clinical applications by controlling the behavior of drug release.

A STUDY ON THE TENSILE STRENGTH OF REINFORCED VENEERING COMPOSITE RESINS FOR CROWN (강화형 치관용 복합레진의 인장강도에 관한 연구)

  • Ahn, Seung-Geun;Kang, Dong-Wan
    • The Journal of Korean Academy of Prosthodontics
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    • v.38 no.2
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    • pp.226-241
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    • 2000
  • Recently a new generation of crown and bridge veneering resins containing submicron glass fillers was introduced. These ultrasmall particle hybrid composite materials distinguish themselves, compared with conventional microfill crown and bridge resins, through improved mechanical properties. It is claimed that these composites are suitable for metal free crowns and even bridges using fiber reinforcement. The purpose of this study was to evaluate the effect of thermal cycling on the tensile strength of the following veneering composites: Artglass(Heraeus Kulzer Co., Wehrheim, Germany), Estonia(Kuraray Co.. Japan), Sculpture(Jeneric Pentron Co., Wallingford, U.S.A.), and Targis(Ivoclar Co., Schaan Liechenstein). According to manufacturer's instructions, rectangular tensile test specimens measuring $1.5{\times}2.0{\times}4.5mm$ were made using a teflon mold. Whole specimens were divided into two groups. One group was dried in a desiccator at $25^{\circ}C$ for 10 days, and another group was subjected to thermal cycling($10,000{\times}$) in water($5/55^{\circ}C$). All test specimens were placed in a universal testing machine and loaded until fracture with a crosshead speed of 0.5mm/min. Weibull analysis and Tukey's test were used to analyze the data. The fracture surfaces of specimens were observed in SEM and the aliphatic C=C absorbance peak of Estenia and Targis resin was analyzed using Fourier transform infrared(FTIR) spectroscopy. Within the limitations imposed in this study, the following conclusions can be drawn: 1. Both in drying condition and thermal cycling condition, the highest tensile strength was observed in Estenia testing group(p<0.05). 2. The strength data were at to single-mode Weibull distribution, and the Weibull modulus of all veneering composite resin specimens increased after thermal cycling treatment. 3. After thermal cycling test, the highest tensile strength was observed in the Estenia group, and the lowest value was observed in the Targis group. The tensile strength values showed the significant differences between each group(p<0.05) 4. The aliphatic C=C absorbance peak of Estonia and Targis resin was decreased after light curing, and there was no distinct change after thermal cycling.

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Diagnosis of the ORF Virus Using a Mixture of Sieving Gel Matrixes in Microchip Gel Electrophoresis (마이크로칩젤 전기영동에서 충진젤 혼합물을 이용한 ORF 바이러스의 진단)

  • Kim, Yun-Jeong;Chae, Joon-Seok;Kang, Seong-Ho
    • Journal of the Korean Chemical Society
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    • v.48 no.5
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    • pp.483-490
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    • 2004
  • We have developed a novel polymerase chain reaction (PCR)-microchip gel electrophoresis (MGE) method based on the sieving gel mixture of commercially available poly(vinylpyrrolidone) (PVP) and hydroxy ethyl cellulose (HEC) for the rapid detection and diagnosis of the orf virus (ORFV) from Korean indigenous goat. After amplification of 594-bp DNA fragment from the B2L gene of ORF virus, the amplicon was analyzed by the MGE separation. The glass microfluidic chip (64 mm total length (36 mm effective length)${\times}$90 ${\mu}$m width${\times}$20 ${\mu}$m depth) allowed the fast detection and diagnosis of ORFV in the mixture of 1.0% PVP ($M_r$ 360,000) and 1.0% HEC ($M_r$250,000) as a sieving matrix with better resolution and reproducibility of DNA fragments. Under the electric field of 277.8 V/cm, the 594-bp DNA was analyzed within 4 min. Compared to traditional slab gel electrophoresis, the PCR-MGE method was twenty times faster and an effective clinical method for the quantitative analysis of ORFV.

Fabrication and characterization of 3-D porous scaffold by polycaprolactone (폴리카프로락톤을 이용한 3차원 다공성 지지체 제조 및 특성 분석)

  • Kim, Jin-Tae;Bang, Jung Wan;Hyun, Chang-Yong;Choi, Hyo Jeong;Kim, Tae-Hyung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.2
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    • pp.58-65
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    • 2016
  • This study was a preparatory experiment aimed the development of membrane scaffolds for tissue engineering. A PCL composite solution contained sodium chloride(NaCl). PCL porous membrane scaffolds were formed on a glass casting plate using a film applicator and immersed in distilled water to remove the NaCl reaching after drying. NaCl was used as a pore former for a 3 dimensional pore net-work. The dry condition parameters were $4^{\circ}C$, room temperature (RT) and $40^{\circ}C$ for each different temperatures in the drying experiment. SEM revealed the morphology of the pores in the membrane after drying and evaluated the in vitro cytotoxicity for basic bio-compatibility. The macro and micro pores existed together in the scaffold and showed a 3-dimensional pore net-working morphology at RT. The in vitro cytotoxicity test result was "grade 2" in accordance with the criterion for cytotoxicity by ISO 10993-5. The dry condition affected the formation of a 3 dimensional pore network and micro and macro pores. Therefore, these results are expected provide the basic process for the development of porous membrane scaffolds to control degradation and allow drug delivery.

Experimental Study on the Stress Variation of Concrete Containing F-fiber Extracted from Waste FRP (폐 FRP로부터 분리한 F-섬유를 이용한 콘크리트 강도 특성 변화에 대한 실험적 연구)

  • Yoon, Koo Young;Park, Jong Won;Lee, Seung Hee
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.17 no.1
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    • pp.42-45
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    • 2014
  • Even though to discard the waste FRP (Fiber-Reinforced Plastic) is urgent and problematic, the way to do it has not been efficient. In our project team the FRP have been splitted into some layers which have different physical properties; mat and roving layers. Among those, the roving layer woven like a basket by bundles of glass fibers has been cut into reusable fibers called 'F-fiber'. F-fiber is 1 mm or 3 mm in width and 3 cm in length. It is used in fiber-reinforced concrete (FRC) with 0.5%, 0.7%, 1.0%, or 1.5% of volume ratio. Produced FRC was tested in compressive, tensile, and bending stress in contrast to the without-fiber (standard) concrete and 0.1% polypropylene reinforced concrete (PP-FRC). The tensile and bending stresses are more or less those of PP-FRC. The compressive stress, however, is similar (with 3 mm F-fiber) to or lower (with 1 mm F-fiber) than that of standard concrete. Conclusively the usage of the waste FRC in concrete is advised to be limited to the one where the compressive stress is not much critical.

Improvement of Silkworm Egg Microinjection Using 3D Printing Technology (3D 프린팅 기술을 이용한 누에 알 미세주입 기술 개선)

  • Jeong, Chan Young;Lee, Chang Hoon;Seok, Young-Seek;Yong, Sang Yeop;Kim, Seong-Wan;Kim, Kee Young;Park, Jong Woo
    • Korean journal of applied entomology
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    • v.61 no.1
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    • pp.249-254
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    • 2022
  • Silkworms, which have for long been used as an insect resource for industrialization, have recently attracted attention as potential bio-factories for the production of novel biomaterials. In this regard, material production is typically achieved based on transformation technology, mediated via microinjection, in which a target gene is inserted into eggs containing an embryo. However, an essential step in the microinjection procedure is egg fixation, which can be a time-consuming and laborious task. Therefore, in this study, using the 3DCADian program, we adopted a 3D printing approach to model egg liners and glue drawers, which can contribute to facilitating egg alignment and fixation, thereby enhancing transformation efficiency by reducing time consumption and fatigue. After rendering using Fusion 360, the two supplementary tools were produced by printing with nylon resin (PA12) and Sinterit Lisa Pro. Subsequent analysis of the time required to fix eggs on glass slides using the two manufactured tools, revealed that the processing time was reduced by approximately 18.6% when the two tools were used compared with when these tools were not used. These innovations not only reduced fatigue but also contributed to more effective use of the microscope and manipulator for microinjection. Consequently, we believe that with additional research and refinement, the egg liner and glue drawer developed in this study could be used to enhance silkworm transformation efficiency and study similar transformation systems in other industrial insects.

A Development of Tapered Metallic Microneedle Array for Bio-medical Application (생체의학에 적용 가능한 테이퍼형태의 금속성 마이코로니들 어레이의 개발)

  • Che Woo Seong;Lee Jeong-Bong;Kim Kabseog;Kim Kyunghwan;Jin Byung-Uk
    • Journal of the Microelectronics and Packaging Society
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    • v.11 no.2 s.31
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    • pp.59-66
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    • 2004
  • This paper presents a novel fabrication process for a tapered hollow metallic microneedle array using backside exposure of SU-8, and analytic solutions of critical buckling of a tapered hollow microneedle. An SU-8 meta was formed on a Pyrex glass substrate and another SU-8 layer, which was spun on top of the SU-8 mesa, was exposed through the backside of the glass substrate. An array of SU-8 tapered pillar structures. with angles in the range of $3.1^{\circ}{\sim}5^{\circ}$ was formed on top of the SU-8 mesa. Conformal electrodeposition of metal was carried out followed by a mechanical polishing using a pianarizing polymeric layer. All organic layers were then removed to create a metallic hollow microneedle array with a fluidic reservoir on the backside. Both $200{\mu}m\;and\;400{\mu}m$ tall, 10 by 10 arrays of metallic microneedles with inner diameters of the tip in the range of $33.6{\sim}101\;{\mu}m$ and wall thickness of $10{\mu}m\;-\;20{\mu}m$ were fabricated. Analytic solutions of the critical buckling of arbitrary-angled truncated cone-shaped columns are also presented. It was found that a single $400{\mu}m$ tall hollow cylindrical microneedle made of electroplated nickel with a wall thickness of $20{\mu}m$, a tapered angle of $3.08^{\circ}$ and a tip inner diameter of $33.6{\mu}m$ has a critical buckling force of 1.8 N. This analytic solution can be used for square or rectangular cross-sectioned column structures with proper modifications.

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Estimation of the Required Number of Fan Coil Unit for Surplus Solar Energy Recovery of Greenhouse (온실의 잉여 태양에너지 회수용 FCU 소요대수 검토)

  • Yun, Sung-Wook;Choi, Man Kwon;Kim, Ha Neul;Kang, Donghyeon;Lee, Siyoung;Son, Jinkwan;Yoon, Yong Cheol
    • Journal of Bio-Environment Control
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    • v.25 no.2
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    • pp.83-88
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    • 2016
  • In this study, previously reported surplus solar energy-related study result and current status of fan coil unit (FCU) for cooling and heating installed in the current sites were briefly examined and then a method to determine the number of FCUs required to recover surplus solar energy was schematically proposed to provide basic data for researchers and technical engineers in this field. The maximum, mean, and minimum outside temperatures during the experiment period were about $28.2^{\circ}C$, $4.4^{\circ}C$, and $-11.5^{\circ}C$, respectively. The horizontal surface solar radiation level outside the greenhouse was in a range of $0.8-20.5MJ{\cdot}m^{-2}$ and mean and total solar radiation were $10.8MJ{\cdot}m^{-2}$ and $1,187.5MJ{\cdot}m^{-2}$. The mean temperature and relative humidity in the greenhouse during the daytime were in a range of 18.8-45.5 and 53.5-77.5%. The total surplus solar energy recovered from the greenhouse during the experiment period was approximately 6,613.4MJ, which could supplement about 6.7% of the total heating energy 98,600.2 MJ. In addition, the number of FCUs installed for heating varies case to case, although similar FCUs are used. Thus, it is necessary to study the installation height, orientation and installation distance as well as the appropriate number of FCUs from the efficient and economical viewpoints. The required numbers of FCUs for surplus solar energy recovery were 8.4-10.9units and 6.1-8.0units based on air mass and circular flow rate that passed through the FCUs. Considering calculation methods and the risks such as efficiency and use environments of FCUs, it was found that about nine units (one unit per $24m^3$ approximately) needed to be installed. The required number of FCUs for surplus solar energy recovery was around one unit per $24m^3$ approximately.

Response of the Growth Characteristics and Phytochemical Contents of Pepper (Capsicum annuum L.) Seedlings with Supplemental LED Light in Glass House (LED 보광처리가 고추(Capsicum annuum) 묘의 생장과 Phytochemical 함량에 미치는 영향)

  • Azad, Md. Obyedul Kalam;Chun, Ik-Jo;Jeong, Jeong-Hak;Kwon, Soon-Tae;Hwang, Jae-Moon
    • Journal of Bio-Environment Control
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    • v.20 no.3
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    • pp.182-188
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    • 2011
  • This research was conducted to evaluate the effect of supplemental light-emitting diode (LED) light on growth characteristics and phytochemical content of pepper (Capsicum annuum L.) seedling using LED blue (470 nm, B), red (660 nm, R), blue + red (BR), far red (740 nm, FR) and UV-B (300 nm) light treatment, and without artificial light. Photon flux of LED light was 49, 16, 40, 5.0 and $0.82{\mu}mol\;m^{-2}s^{-1}$ for B, R, BR, FR, and UV-B light, respectively, during experiment. Supplemental LED light duration was $16hr\;day^{-1}$ and UV-B light duration was 10 min. per day after sunset up to 15 days (12 days after germination) of plants age. In our research, growth characteristics and phytochemical content of pepper seedlings were greatly influenced by supplemental LED light compare to control treatment. Red light increased the number of leaves, number of nodes, leaf width and plant fresh weight by 34%, 27%, 50% and 40%, respectively. Blue light increased the leaf length by 13%, and stem length and length of inter node were increased by 17% and 34%, respectively under grown far red light. After 15 days of light treatments phytochemical concentrations of pepper plants were significantly changed. Blue light enhanced the total anthocyanin and chlorophyll concentration by 6 times and 2 times, respectively. Red light increased the total phenolic compound at least two folds meanwhile far red light reduced the ascorbic acid and antioxidant activity 31% and 66%, respectively compared to control treatment.