• Archives of Pharmacal Research
• /
• v.29 no.3
• /
• pp.188-190
• /
• 2006

In this study, a newly-synthesized metalloporphyrin, Gd-chlorin (PB Chlorin), was investigated by using a simple tissue phantom to test its efficacy as an MRI contrast agent. This study demonstrated the potential activity of Gd-chlorin as not only a MRI contrast agent, but also as a PDT photosensitizer by using a simple tissue phantom and conducting a very brief MRI experiment.

• Textile Coloration and Finishing
• /
• v.33 no.4
• /
• pp.317-326
• /
• 2021

In this study, we investigated for Bio-EPDM foam with oyster shell surface modified earth coupling agent. Experiments were carried out to confirm the bio-EPDM/Oyster shell foam applying content of earth coupling agent. The cure characterization were evaluated by measuring the mooney viscosity and oscillating disc rheometer (ODR). Mechanical properties such as hardness, tensile strength, elogation at break and tear strength were measured, and changes of mechanical properties were also evaluated after immersion in NaCl solution. In addition degree of volume change was measured after immersing the Bio-EPDM foam in NaCl solution and the low-temperature permanent compression set was evaluated at 4℃. To evaluate the low-temperature characteristics of Bio-EPDM/Oyster shell, the glass transition temperature was measured using Differential Scanning Calorimeter (DSC). As a result as the content of the earth coupling agent increased up to 3phr, the crosslinking density and mooney viscosity increased, and the mechanical properties and low-temperature permanent compression set improved, but from 4phr, it was rather decreased. The change in the glass transition temperature was insignificant, and the foam cell appeared to be uniform when the earth coupling agent was applied.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.20 no.4
• /
• pp.252-259
• /
• 2008

The purpose of this study is to estimate the movement of microbial contaminant caused by bio-attack using bio-agent such as bacillus anthracis for preventing contaminant diffusion. multizone simulation was carried out in the case of three types of bio-attack scenario in the government building. Simulation results show that severe contaminant diffusion is brought about in all cases of bio-attack scenario in one hour, though pollution boundaries have different mode according to bio-attack scenarios. Simulation results also show that immune building technology such as filter and UVGI technology gives us powerful alternatives to meet the emergent situation caused by unexpected bio-attack.

• Journal of the Korea Institute of Military Science and Technology
• /
• v.26 no.1
• /
• pp.102-112
• /
• 2023

This research mainly focuses on the transport and dispersion of chemical agent plume according to the Lagrangian Puff Model and Lagrangian Particle Model of NBC_RAMS(Nuclear, Biological, Chemical Reporting And Modeling S/W System). NBC_RAMS was developed with the purposes of estimating the fate of Chemical, Biological, and Radioactive(CBR) agent plumes and evaluating damages in the Republic of Korea. First, it calculates the local weather pattern, i.e. wind speed, wind direction, and temperature, by considering the effects of land uses and topography. The plume behaviors are calculated by adopting the Lagrangian Puff Model(LPFM) or Lagrangian Particle Model(LPTM). In this research, we assumed a virtual chemical agent exposure event in a stable atmospheric condition during the summer season. The plume behaviors were estimated by both LPFM and LPTM on the used area(urbanized and dry area) and the agricultural land. The higher heat flux in the used area led to stronger winds and further downward movement moving of the chemical agent than the farmland. The lateral dispersion of the chemical plume was emphasized in the Lagrangian Puff Model because it adopted Gaussian distribution.

• Journal of Information Technology Services
• /
• v.10 no.1
• /
• pp.177-190
• /
• 2011

Due to the growth of economy and the advancement of IT, the life expectancy has been prolonged and the interests in health have greatly increased. Recently the request for systems that enable measuring the bio-signals of patients in the non medical organizations, such as home, and transmitting them to medical staffs at remote sites for monitoring them. In this paper, we present an agent-based u-health system for patients or suspects with heart diseases. Our system consists of portable devices for measuring bio-signals and agents that perform data collection, data storage, automatic detection of abnormal status in patients, and HL7-based data exchange in a cooperative way. The main features of the system are : the agent-based architecture facilitates the addition of new service modules as well as the modification of existing ones; an intelligent agent is provided which automatically detects situations in which the bio-signals of patients are abnormal; the medical data standard is supported so that the communication with other systems is very easy. To our survey, there have been few previous systems which support all those features in a seamless way.

• Journal of Microbiology and Biotechnology
• /
• v.16 no.12
• /
• pp.1904-1911
• /
• 2006

The cell-free extracts of 250 yeasts were screened for their in vitro anti-angiogenic activity, to develop a new cancer metastasis inhibitor. Saccharomyces cerevisiae K-7 was selected as the producer of the anti-angiogenic agent, because it had the highest anti-angiogenic activity. The anti-angiogenic agent was produced maximally from hydrolysates of Saccharomyces cerevisiae K-7, when the yeast was cultured in yeast extract-peptone-dextrose medium at 30$^{\circ}C$ for 24 h, and cell-free extracts were than digested with pepsin for 4 h at 37$^{\circ}C$. The anti-angiogenic agent was further purified by ultrafiltration, Sephadex G-25 gel permeation chromatography and reverse-phase HPLC, and the anti-angiogenic activity of the final purified preparation was 72.7% at 10 $\mu$M/egg. The purified anti-angiogenic agent was found to originate from the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) molecule of Saccharomyces cerevisiae K-7, and its peptide sequence was Val-Ser-Trp-Tyr-Asp-Asn-Glu-Tyr-Gly-Tyr-Ser-Thr-Arg-Val-Val-Asp. In the MTT assay, the shape of the HT-l 080 cell was clearly changed to a circular type at 0.2 mM purified anti-angiogenic agent. This result indicated that the growth of the HT-I080 cell was significantly inhibited at 0.2 mM of the purified anti-angiogenic agent. The MMP activity of the treated HT-l080 cells was not affected, evidenced by the gelatin zymography, indicating that the anti-angiogenic mechanism of the purified anti-angiogenic agent is not mediated through MMP activity.

• Journal of KIISE:Computing Practices and Letters
• /
• v.13 no.7
• /
• pp.545-549
• /
• 2007

The Bio-Inspired System focuses on the creation of an effective system model for massive network applications and is being widely developed. However, the system has a problem-difficulty implementing three features in the system, which includes scalability, adaptability and survivability. To solve this problem, we designed an Ecogent as a multiple intelligence agent, and a Bio-platform to address the three features of scalability, adaptability and survivability. The Bio-Inspired System Platform consists of an ERS (Ecogent Runtime Services) Platform and a Bio-Platform. The ERS platform serves the basic functions of mobile agents, such as Registration, Life Cycle, Migration, Communication, Location and Fault Tolerance. The Bio-Platform includes the functions of Evolution Control and Stigmergy Control to address evolution and adaptation.

• Bulletin of the Korean Chemical Society
• /
• v.32 no.1
• /
• pp.117-121
• /
• 2011

Size-controlled Ag nanoparticles (NPs) were prepared from the decomposition of Ag(I) carboxylates using ethanolamine derivatives as a reducing agent without an additional stabilizing agent. The size of the Ag NPs with a narrow size distribution (sub-10 nm to ca. 40 nm) was controlled precisely by varying the processing parameters, such as the type of reducing agent and the chain length of the carboxylate in the Ag(I) carboxylate. The optical properties, surface composition and crystallinity of the Ag NPs were characterized by ultraviolet-visible spectroscopy, gas chromatography-mass spectrometry, thermal gravimetric analysis, transmission electron microscopy and X-ray diffraction.

• Proceedings of the Korean Society for Applied Microbiology Conference
• /
• 2004.06a
• /
• pp.337-341
• /
• 2004

• The Journal of Korea Robotics Society
• /
• v.2 no.4
• /
• pp.317-326
• /
• 2007

Recently, robotic automation in clinical laboratory becomes of keen interest as a fusion of bio and robotic technology. In this paper, we present a new robotic platform for clinical tests suitable for small or medium sized laboratories using mobile robots. The mobile robot called Mobile Agent is designed as transfer system of blood samples, reagents, microplates, and any instruments. Also, the developed mobile agent can perform diverse tests simultaneously based on its cooperative and distributed ability. The driving circuits for the mobile agent are embedded in the robot, and each mobile agent communicates with other agents by using Bluetooth communication. The RFID system is used to recognize patient information. Also, the magnetic hall sensor is embedded to remove and compensate the cumulated error of locomotion at the bottom of mobile agent. The proposed mobile agent can be easily used for various applications because it is designed to be compatible with general software development tools. The Mobile agents are manufactured, and feasibility of the robot and localization of the agents using magnetic hall sensor are validated by preliminary experiments.