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Gadolinium-Chlorin is Potentially a New Tumor Specific MRI Contrast Agent  

Kim Jong-Ki (PDT BIO CO., Ltd., Departments of Radiology and Biomedical Engineering, Catholic University Hospital of Taegu)
Kim Dong-Myung (PDT BIO CO., Ltd.)
Kang Min-Suk (PDT BIO CO., Ltd.)
Kim Hae-Kyung (PDT BIO CO., Ltd.)
Kim Jeong-Sook (PDT BIO CO., Ltd.)
Yu Eun-Kyung (PDT BIO CO., Ltd.)
Jeong Jin-Hyun (PDT BIO CO., Ltd., College of Pharmacy, Kyung Hee University)
Publication Information
Archives of Pharmacal Research / v.29, no.3, 2006 , pp. 188-190 More about this Journal
Abstract
In this study, a newly-synthesized metalloporphyrin, Gd-chlorin (PB Chlorin), was investigated by using a simple tissue phantom to test its efficacy as an MRI contrast agent. This study demonstrated the potential activity of Gd-chlorin as not only a MRI contrast agent, but also as a PDT photosensitizer by using a simple tissue phantom and conducting a very brief MRI experiment.
Keywords
Metalloporphyrin; Gadolinium; MRI contrast agent; PDT photosensitizer;
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