• 기술혁신학회지
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• 제15권1호
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• pp.185-202
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• 2012

본 연구는 정부의 대표적인 대형연구개발사업인 21세기 프론티어 연구개발 사업의 성과에 영향을 미치는 요인을 분석하여 향후 대형 연구개발 사업을 추진하는 정부 정책 결정자와 연구단 관계자에게 정책적인 시사점을 주는데 목적이 있다. 기존 대형연구개발사업의 프로그램에 대한 성과분석과 평가는 일부 있었지만, 연구주체, 연구유형, 연구기간, 연구 분야에 따른 성과 특성과 성과에 영향을 미치는 요인을 분석한 연구는 부족한 실정이다. 이를 위해 교육과학기술부가 추진 중인 21세기 프론티어 연구개발 사업단 중 2010년과 2011년 사업단의 연구기간이 종료된 8개 사업단 과제 전체를 대상으로 정책요인별로 가설을 설정하였다. 사업을 수행한 연구주체의 소속(산업체, 대학, 출연연구소)에 따라 연구 성과에 차이가 있는지, 연구유형(기초, 응용, 개발)에 따라 성과에 차이가 있는지, 연구기간에 따라 성과에 차이가 있는지, 연구과제의 기술분야별로 성과에 차이가 있는지 등을 검증하였다. 연구 성과는 대학의 논문 성과가 출연연이나 산업체에 비해 높은 것으로 나타났으며, 산업체는 특허의 국외 출원과 등록이 높은 것으로 나타났다. 개발연구는 국내출원과 등록, 국외출원과 기술이전 계약의 성과가 높은 것으로 나타났으며, 장기간(6년 이상)의 연구가 단기 연구보다 국내출원이 높은 것으로 나타났다. 연구 대상 기술 분야(바이오, 나노, 에너지환경기술)별로도 연구 성과의 차이가 있음을 확인하였다.

• 농촌계획
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• 제28권1호
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• pp.1-15
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• 2022

A Care farm is known to have positive effects on various people in psychological, physical, and social aspects. However, care farm services for the disabled, transportation disadvantaged, and socially disadvantaged are limited. This study conducted a demand survey in order to provide basic data for development of the Agro-Healing Virtual Reality Therapy(AVRT) system. The respondents were the ordinary person(n=127) and the disabled person(n=72), and the survey items consisted of 4 categories and 20 items, including intention to use AVRT, requirements for use, factors to be considered when developing the system, and content and program preferences. The intention to use a AVRT was found to be at a high level of 80% or more by respondent characteristics. In addition, similar results were shown in all items such as virtual reality experience, willingness to use, appropriate use time, and willingness to pay by respondent characteristics, and correlation by item was determined through correlation analysis. As for the conditions of use, both sides preferred rural types and were found to have the purpose of healing. However, there were concerns about dizziness in common between system use, and in the case of the disabled person, there were difficulties in purchasing expensive equipment. In the development of the AVRT system, the part of sensory priority, important technology level, and color preference were evaluated, and the preference of content and programs to be developed in the system was identified. Fruit, vegetables, flowers, and animals preferred mandarin, tomato, tulips, and dogs first, horticultural healing preferred harvest management for the ordinary person, plant cultivation for the disabled person, and forest healing and animal education preferred walking and dog-related programs. However, agricultural work was found to be a program with high preference for making processed foods for the ordinary person and creating an animal breeding environment for the disabled person. The result of this study is expected to provide reference data that can be suggested for the development of Agro-healing Virtual Reality Therapy system.

• Ocean and Polar Research
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• 제39권1호
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• pp.1-11
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• 2017

The aim of this study was to determine the physiological response and the applicable concentration ranges of anesthetic clove oil and anesthetic lidocaine-HCl, and to investigate the synergistic effect of a mixture of these two anesthetics on the in grass puffer (Takifugu niphobles). The anesthesia times decreased and the recovery times increased with increasing concentrations of clove oil and lidocaine-HCl. Applicable concentration ranges for long-term transportation requiring more than 1 hour were 2 ppm for clove oil and 50 ppm for lidocaine-HCl. With mixtures of the two anesthetics, the anesthesia time decreased as the admixture concentration of clove oil and lidocaine-HCl increased. Anesthesia times of experimental groups with the combined anesthetics were shorter than those with the same concentrations of clove oil or lidocaine-HCl alone. Plasma cortisol concentrations were highest at 6 hours in all experimental groups anesthetized with the mixture of clove oil and lidocaine-HCl, while all groups with clove oil or lidocaine-HCl alone had the highest plasma cortisol concentrations at 12 hours. Plasma glucose concentrations were highest at 12 hours in experimental groups anesthetized with the mixture of clove oil and lidocaine-HCl, while groups with clove oil or lidocaine-HCl alone had the highest plasma glucose at 24 hours. The results of this study provide basic information about anesthetics and the synergistic effect of mixtures of anesthetics in this fish species. This information should be useful for aquaculturists who require methods for safe and easy fish handling, and for transporters who require that minimal stress is imposed on fish during transport.

• 지능정보연구
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• 제23권4호
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• pp.169-196
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• 2017

제4차 산업혁명의 도래로 IT(information technology)를 활용한 다양한 융합기술에 대한 관심이 높아지고 있으며, 이에 따른 고품질의 IT관련 교육서비스 제공의 필요성 및 중요성 또한 점차 증대되고 있다. 한편, 일반적인 교육서비스 품질 및 만족도에 관한 연구는 그 동안 다양한 맥락에서 활발히 진행된 바 있으나, IT교육 참가자를 대상으로 한 IT교육 서비스품질의 역할을 살펴본 연구는 상대적으로 부족한 것으로 파악된다. 이에 본 연구에서는 SERVPERF 모형 및 관련 선행연구를 바탕으로 IT교육 맥락에서 IT교육 서비스품질의 다섯 가지 차원(유형성, 신뢰성, 반응성, 확신성 및 공감성)을 도출하고, 이러한 세부 IT교육 서비스품질 요인이 학습자의 교육만족도, 나아가 현업적용의도 및 추천의도에 미치는 영향을 검증하였다. 또한, 이러한 영향이 학습자 직위(실무자 집단/관리자 집단) 및 참여동기(자발적 참여집단/비자발적 참여집단)에 따라 어떻게 달라지는지에 대한 추가분석도 실시하였다. 서울 소재 'M'교육기관 203명의 IT교육 참가자 대상 설문을 활용한 구조방정식모형 분석 결과, IT교육 서비스품질의 다섯 가지 차원 가운데 유형성, 신뢰성 및 확신성이 교육만족도에 유의한 영향을 주는 것으로 나타났으며, 이러한 교육만족도는 현업적용의도와 추천의도에도 유의한 영향을 주는 것으로 조사되었다. 또한, IT교육 서비스품질이 교육만족도에 미치는 영향 관계에서 학습자 직위 및 참여동기가 유의한 조절효과를 가진다는 사실을 확인하였다. 본 연구는 SERVPERF 모형을 활용하여 IT교육 맥락에서 IT교육 서비스품질의 영향력을 실증한 최초의 연구라는 점에서 학술적 의의가 있다. 본 연구결과가 IT교육 서비스 제공기관의 교육만족도 제고 및 효율적인 서비스 운영을 위한 실질적인 지침을 제공해 줄 수 있을 것으로 기대한다.

• 한국산학기술학회논문지
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• 제20권4호
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• pp.76-85
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• 2019

Vegetable oil은 자연 유래 물질로 낮은 가격 및 친환경적이라는 장점으로 최근 다양한 연구가 진행되고 있다. 하지만 vegetable oil 내의 이중결합의 낮은 반응성으로 인해 고분자 합성의 기반 물질로 사용하기 위해서는 반응성이 높은 관능기로 치환하여 사용하는 경우가 많다. Tung oil은 ${\alpha}$-eleostearic acid를 주성분으로 하는데, 이 구조는 3개의 이중결합이 공명구조 형태로 되어있기 때문에 다른 vegetable oil과는 달리 높은 반응성을 보인다. 본 연구에서는 이러한 tung oil을 styrene 및 divinylbenzene 등의 monomer와 양이온 중합을 통해 tung oil의 관능기 치환 과정이 없는 열경화성 수지를 합성하였으며, 각 monomer의 조성이 합성된 열경화성 수지에 미치는 영향을 확인하기 위해 열적 기계적 물성을 측정하였다. 그 결과, tung oil-styrene-divinybenzene copolymer는 단일 Tg를 갖는 homogeneous한 열경화성 고분자를 형성하는 것을 확인하였으며, 기계적 물성의 변화를 통해 tung oil 및 styrene은 soft segment로써 합성된 copolymer에 elastic한 성질을 부여하고, divinylbenzene은 hard segment로 작용하여 합성된 copolymer에 brittle한 성질을 부여하는 것을 확인하였다.

• 농촌계획
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• 제27권1호
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• pp.57-70
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• 2021

The degree of benefits of living services related to the quality of life can solve the depopulation problem, and it is necessary to be able to quantitatively analyze problems related to the quality of life in rural areas in order to cope with the rural depopulation. The purpose of this study was to develop the assessment model of a village-level rural living service that reflects the regional characteristics of rural villages to evaluate the level of rural living services for response rural depopulation. Based on the review of previous related studies, the evaluation index was composed of seven sectors of education, health, welfare, culture, environment, safety, and convenience, and the assessment model of a rural living service was established. This model was evaluated through a sample survey of 90 villages in Nonsan-si, Seongju-gun, and Pyeongchang-gun. As a result of the rural life services evaluation by Si and Gun, Seongju-gun, which is affected by nearby large cities, has the largest variation by village level and is assessed at a lower level overall than other Si and Gun. As a result of the rural life services evaluation by 7 sectors, in the case of health and welfare, low scores were shown in the assessment model, but the level of residents' satisfaction was mid-level. In particular, in the case of Seongju-gun, there were significant differences in the assessment model and the survey results of the level of residents' satisfaction in the health and welfare sectors due to the influence of nearby large cities. As a result of analyzing the number of villages corresponding to the top 30% and the bottom 30% of the evaluation results for each sector, it was analyzed that the villages with the highest evaluation results in Pyeongchang-gun in both the assessment model and the level of residents' satisfaction. It implies that quantitative analysis of data based index and accessibility as well as level satisfaction of residents are necessary.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3451-3455
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• 2014

Background: The serum carcinoembryonic antigen (CEA) level can reflect tumor growth, recurrence and metastasis. It has been reported that epidermal growth factor receptor (EGFR) mutations in exons 19 and 21may have an important relationship with tumor cell sensitivity to EGFR-TKI therapy. In this study, we investigated the clinical value of EGFR mutations and serum CEA in patients with non-small cell lung cancer (NSCLC). Materials and Methods: The presence of mutations in EGFR exons 19 and 21 in the tissue samples of 315 patients with NSCLC was detected with real-time fluorescent PCR technology, while the serum CEA level in cases who had not yet undergone surgery, radiotherapy, chemotherapy and targeted therapy were assessed by electrochemical luminescence. Results: The mutation rates in EGFR exons 19 and 21 were 23.2% and 14.9%, respectively, with the two combined in 3.81%. Measured prior to the start of surgery, radiotherapy, chemotherapy and targeted treatment, serum CEA levels were abnormally high in 54.3% of the patients. In those with a serum CEA level <5 ng/mL, the EGFR mutation rate was 18.8%, while with 5~19 ng/mL and ${\geq}20ng/mL$, the rates were 36.4% and 62.5%. In addition, in the cohort of patients with the CEA level being 20~49 ng/mL, the EGFR mutation rate was 85.7%, while in those with the CEA level ${\geq}50ng/mL$, the EGFR mutation rate was only 20.0%, approximately the same as in cases with the CEA level<5 ng/mL. Conclusions: There is a positive correlation between serum CEA expression level and EGFR mutation status in NSCLC patients, namely the EGFR mutation-positive rate increases as the serum CEA expression level rises within a certain range (${\geq}20ng/mL$, especially 20~49 ng/mL). If patient samples are not suitable for EGFR mutation testing, or cannot be obtained at all, testing serum CEA levels might be a simple and easy screening method. Hence, for the NSCLC patients with high serum CEA level (${\geq}20ng/mL$, especially 20~49 ng/mL), it is worthy of attempting EGFR-TKI treatment, which may achieve better clinical efficacy and quality of life.

• 분석과학
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• 제25권3호
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• pp.190-196
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• 2012

납에 의한 노출에 대한 평가에는 주로 전혈 중 납을 사용하고 있으나 전혈 중 납은 납의 단기 노출에 대한 정보만을 제공한다는 단점이 있다. 납 노출의 만성적 노출지표인 혈장 중 납을 분석하기 위해서는 수 ng/L의 극미량 분석이 요구되어 납의 만성지표로서의 효용성 검증에 어려움이 있다. 본 연구에서는 납 노출 근로자의 만성 노출 지표로서 혈장 중 납을 분석하기 위하여 유도결합플라즈마 질량분석법을 정립하였다. 외부환경으로부터의 오염을 최소화시키기 위해 class 1,000 수준의 청정실을 설치한 후 가동 전과 후의 부유 분진량을 확인한 후 극미량 시료 분석을 수행하였다. 표준 우태아 혈청을 이용하여 표준물 첨가법에 의한 표준편차를 이용하여 계산한 최소검출한계는 4.3 ng/L, 최소정량한계는 12.2 ng/L이었으며, 신호-대-잡음 비로 계산한 최소검출한계는 7.0 ng/L, 최소정량한계는 22.1 ng/L이었다. 20 ng/L부터 2,000 ng/L 농도 범위에서 정밀도는 4% 이내였으며, 우태아 혈청에 20-2,000 ng/L의 농도로 첨가하여 계산한 회수율은 92.3-101.3%로 양호한 결과를 얻었다. 본 연구에서 제시한 방법을 사용하여 납 노출근로자의 혈장 및 혈청 중 납 분석이 가능하였으며 이를 통해 납의 만성노출에 대한 조사가 가능할 것으로 판단된다.

• Interdisciplinary Bio Central
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• 제5권4호
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• pp.7.1-7.3
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• 2013

This essay describes G. Mendel's life and his law of inheritance. He was born in a poor family in 1822 in a hamlet in Czechs. At that time the Habsburg Empire dominated over the East Europe in which Vienna was the capital. Vienna had thus been the center of culture and learning, and attracted many artists and scholars such as W. Mozart (1756- 1791), L. Beethoven (1770-1827), C. Doppler (1803-1853), S. Freud (1856-1939), G. Mahler (1860-1911), G. Klimt (1862-1918) and E. Schiele (1890-1918). Beethoven came to Vienna to learn from Mozart. Klimt was influence by Schilele. When Mahler consulted Freud about his mental problem, Freud said to him "Your mental condition was not normal, but the condition made you creative. So, do not worry too much about it." Like that, there were many interactions among them, and Mendel was no exception. Though Mendel was poor, he was fortunate in his education and scientific research, because he could have excellent supporters in his family and out of it. He learned mathematics and physics at Vienna University under the guidance of C. Doppler. He was not totally alone when he discovered his law of inheritance. It may not be true either that his law was neglected and rediscovered in the year of 1900. As his one and only paper indicates, he was one of the earliest interdisciplinary scientists.

• Journal of Welding and Joining
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• 제33권3호
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• pp.40-46
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• 2015

Welding is one of the most fundamental and necessary work in the industry that demand sophistication of skilled workers. This study is to introduce welding simulator as a training tool, to verify its effectiveness and to measure satisfaction of the trainees. A group of freshman students at a Korea Polytechnics College in their twenties with less experience of welding participated in the study. They were divided into two groups and took a traditional training course (comparison group) and a training course with welding simulator applied reality/haptic technology (experimental group) for same hours respectively. To evaluate training effect, a national certificate test and a survey based on Phillips' ROI (Return on Investment) methodology were conducted by the students and the college respectively. And satisfaction survey among the students based on Kirkpatrick's Four-Level Evaluation Model was also carried out. The results showed that all students in the experimental group passed the national certificate test and the ROI of the experimental group for five years were 110% higher than the comparison group. Furthermore, 25% more students in the experimental group replied "very satisfied" about the overall training course and 75% more students in the same group found that the simulation was very similar to the real welding.