• International journal of advanced smart convergence
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• 제12권1호
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• pp.18-30
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• 2023

We compared empirically the forecast accuracies of the LSTM model, and the ARIMA model. ARIMA model used auto.arima function. Data used in the model is 100 days. We compared with the forecast results for 50 days. We collected the stock closing prices of the top 4 companies by market capitalization in Korea such as "Samsung Electronics", and "LG Energy", "SK Hynix", "Samsung Bio". The collection period is from June 17, 2022, to January 20, 2023. The paired t-test is used to compare the accuracy of forecasts by the two methods because conditions are same. The null hypothesis that the accuracy of the two methods for the four stock closing prices were the same were rejected at the significance level of 5%. Graphs and boxplots confirmed the results of the hypothesis tests. The accuracies of ARIMA are higher than those of LSTM for four cases. For closing stock price of Samsung Electronics, the mean difference of error between ARIMA and LSTM is -370.11, which is 0.618% of the average of the closing stock price. For closing stock price of LG Energy, the mean difference is -4143.298 which is 0.809% of the average of the closing stock price. For closing stock price of SK Hynix, the mean difference is -830.7269 which is 1.00% of the average of the closing stock price. For closing stock price of Samsung Bio, the mean difference is -4143.298 which is 0.809% of the average of the closing stock price. The auto.arima function was used to find the ARIMA model, but other methods are worth considering in future studies. And more efforts are needed to find parameters that provide an optimal model in LSTM.

• Natural Product Sciences
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• 제15권4호
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• pp.192-197
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• 2009

Chemical investigation of the aerial parts of Artemisia iwayomogi has afforded five glycoside compounds. Their chemical structures were characterized by spectroscopic methods to be turpinionoside A (1), (Z)-3-hexenyl O-${\alpha}$-arabinopyranosyl-(1${\rightarrow}$6)-O-${\beta}$-D-glucopyranoside (2), (Z)-5'-hydroxyjasmone 5'-O-${\beta}$-Dglucopyranoside (3), (-)-syringaresinol-4-O-${\beta}$-D-glucopyranoside (4), and methyl 3,5-di-O-caffeoyl quinate (5). All of them were isolated for the first time from Artemisia species. The effect of compounds 1 - 5 on the function of osteoblastic MC3T3-E1 cells was examined by checking the cell viability, alkaline phosphatase (ALP) activity, collagen synthesis, and mineralization. Turpinionoside A (1) significantly increased the function of osteoblastic MC3T3-E1 cells. Cell viability, ALP activity, collagen synthesis, and mineralization were increased up to 117.2% (2 ${\mu}M$), 110.7% (0.4 ${\mu}M$), 156.0% (0.4 ${\mu}M$), and 143.0 % (2 ${\mu}M$), respectively.

• Journal of Microbiology and Biotechnology
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• 제14권5호
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• pp.1067-1070
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• 2004

In the course of screening for specific inhibitors against the mycelial form of Candida albicans from natural resources, we have isolated and identified A6792-1 from Streptomyces sp. A6792 by using several chromatographies. By spectral analyses, this compound was determined as 7-oxostaurosporine, having a structure of staurosporine aglycon noiety. 7-Oxostaurosporine exhibited a selective growth inhibitory activity against the mycelial form of Candida spp. up to $100\mu\textrm{g}/disc$ in bioassay. It also exhibited a specific antifungal activity against the mycelial form of Candida spp. including C. krusei, C. albicans, C. tropicalis, and C. lusitaniae with MICs ranging from 3.1 to $25\mu\textrm{g}/ml$ 7-Oxostaurosporine demonstrated no in vivo toxicity in SPF ICR mice. Therefore, this compound may have a considerable potential as an antifungal agent based on the preferential inhibition against growth of the mycelial form of Candida spp., dimorphic fungi.

• Journal of the Optical Society of Korea
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• 제13권1호
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• pp.116-122
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• 2009

In this paper, a robust method is developed to locate the irises of both eyes. The method doesn't put any restrictions on the background. The method is based on the AdaBoost algorithm for face and eye candidate points detection. Candidate points are tuned such that two candidate points are exactly in the centers of the irises. Mean crossing function and convolution template are proposed to filter out candidate points and select the iris pair. The advantage of using this kind of hybrid method is that AdaBoost is robust to different illumination conditions and backgrounds. The tuning step improves the precision of iris localization while the convolution filter and mean crossing function reliably filter out candidate points and select the iris pair. The proposed structure is evaluated on three public databases, Bern, Yale and BioID. Extensive experimental results verified the robustness and accuracy of the proposed method. Using the Bern database, the performance of the proposed algorithm is also compared with some of the existing methods.

• 제어로봇시스템학회논문지
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• 제18권2호
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• pp.126-132
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• 2012

The technique for estimation of sound source direction is one of the important methods necessary for various engineering fields such as monitoring system, military services and so on. As a new approach for estimation of sound source direction, this paper propose the bio-mimetic localization sensor based on mechanically coupling structure motivated by hearing structure of fly, Ormia Ochracea. This creature is known for its outstanding recognition ability to the sound which has large wavelength compared to its own size. ITTF (Inter-Tympanal Transfer Function) which is the transfer function between displacements of the tympanal membranes on each side has the all inter-tympanal information dependent on sound direction. The peak and notch features of desired ITTF can be generated by using the appropriate mechanical properties. A example of estimation of sound source direction using generated ITTF with monotonically changing notch and peak patterns is shown.

• 대한의생명과학회지
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• 제25권1호
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• pp.7-14
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• 2019

Alzheimer's disease (AD) is highly prevalent in dementia, with no specifically effective treatment having yet been discovered. Amyloid plaques are one of the key hallmarks of AD. Transgenic mouse models exhibiting Alzheimer's disease-like pathology have been widely used to study the pathophysiology of Alzheimer's disease. In this study, we showed an age-dependent correlation between cognitive function, pathological findings, and [F-18] Florbetaben (FBB) PET images. Nineteen transgenic mice (12 with AD, 7 with controls) were used for this study. We observed an increase in ${\beta}$-Amyloid deposition ($A{\beta}$) in brain tissue and [F-18] FBB amyloid PET imaging in the AD group. The [F-18] FBB data showed a mildly negative trend with cognitive function. Pathological findings were negatively correlated with cognitive functions. These finding suggests that amyloid beta deposition can be well-monitored with [F-18] FBB PET and a decline in cognitive function is related to the increase in amyloid plaque burden.

• 한국의류학회지
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• 제47권1호
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• pp.1-16
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• 2023

The smart fashion industry is showing steady growth worldwide, which will create new value throughout the fashion industry and become an essential element for efficient lifestyles. This study attempted to examine the development trend of smart fashion products from a design perspective and present the direction of design as a fashion item incorporating smart technology from a functional perspective. For this purpose, the category of portable smart fashion and the characteristics of the research object were considered through current status survey and previous research review. Among smart fashion, accessories and clothing/fabric products that have been released thus far that apply portable fashion design principles are selected and its characteristics are analyzed. In addition, function keywords were extracted based on the product description provided by the manufacturer and the function-oriented types were classified to identify each type's design characteristics. Therefore, the area receiving the signal and the sensor size should be considered, as should the fashion accessory type that combines various materials and colors. The clothing/textile type requires a design that mainly focuses on functions related to bio-signal interactions.

• 생물환경조절학회지
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• 제23권1호
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• pp.39-42
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• 2014

본 연구의 목적은 선형, 쌍곡선, 베타 함수를 이용하여 상추의 주요 온도를 예측하기 위함이다. 상추 종자를 항온 생육상에서 발아시켰다. 온도처리는 $10^{\circ}C$, $14^{\circ}C$, $16^{\circ}C$, $20^{\circ}C$, $24^{\circ}C$, $28^{\circ}C$와 $32^{\circ}C$였다. 100개의 종자를 9cm 페트리디쉬에 필터페이퍼 2장을 깔고 4반복 실시하였다. 유근이 1mm 나왔을 때를 발아로 하였다. 시간에 따른 발아율은 로지스틱 함수로 계산하였다. 최저, 최적, 최고 온도는 50% 발아한 시점의 역수를 온도에 따른 함수로 표기하여 나타내었다. 선형 함수의 경우, 최저, 최적, 최고 온도는 각각 $7.9^{\circ}C$, $23.3^{\circ}C$, $28.0^{\circ}C$였으며, 쌍곡선 함수의 경우, 최저, 최적, 최고 온도는 각각 $9.7^{\circ}C$, $19.5^{\circ}C$, $29.4^{\circ}C$였으며, 베타 함수인 경우, 최저, 최적, 최고 온도는 각각 $3.7^{\circ}C$, $20.7^{\circ}C$, $32.0^{\circ}C$였다. 최저, 최적, 최고 온도 범위는 각각 $3.7{\sim}7.9^{\circ}C$, $19.5{\sim}23.3^{\circ}C$, $28.0{\sim}32.0^{\circ}C$이었다.

• Journal of Photoscience
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• 제9권2호
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• pp.182-185
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• 2002

There are 3 UV DNA repair endonuclease activities in mammalian cells that cleave UV -irradiated DNA. Interestingly, mammalian UV endonuclease III with MW of 26.7kD has a lyase activity on AP sites. It also cleaves the phosphodiester bond within a cyclobutane pyrimidine dimer. Genomic analysis of human repair endonuclease III gene revealed that this gene has 100% sequence identity with ribosomal protein S3 (rpS3). Therefore, rpS3 seems to function both in translation and in DNA repair. This gene of about 6.1 kb contains 6 introns and 7 exons, and the first and fifth introns of human rpS3 gene contain functional U15 small nucleolar (sno) RNAs which appear to be involved in ribosome assembly. It is to be noted that the column profile of the endonuclease activity of rpS3 appears to be altered in Xeroderma Pigmentosum (XP) group D cells compared to normal cells indicating that this protein is involved in XP disease as well. XP is a human disease characterized by high sensitivity of skin by UV- or sun-light irradiation and by high frequency of developing skin cancers. We also report here that rpS3 protein is involved in other cellular functions.

• Molecules and Cells
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• 제37권10호
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• pp.705-712
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• 2014

The early steps of neural development in the vertebrate embryo are regulated by sets of transcription factors that control the induction of proliferative, pluripotent neural precursors, the expansion of neural plate stem cells, and their transition to differentiating neural progenitors. These early events are critical for producing a pool of multipotent cells capable of giving rise to the multitude of neurons and glia that form the central nervous system. In this review we summarize findings from gain- and loss-of-function studies in embryos that detail the gene regulatory network responsible for these early events. We discuss whether this information is likely to be similar in mammalian embryonic and induced pluripotent stem cells that are cultured according to protocols designed to produce neurons. The similarities and differences between the embryo and stem cells may provide important guidance to stem cell protocols designed to create immature neural cells for therapeutic uses.