• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVII)
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• pp.948-948
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• 2005

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVII)
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• pp.949-949
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• 2005

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVII)
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• pp.950-950
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• 2005

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVII)
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• pp.951-951
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• 2005

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVII)
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• pp.975-975
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• 2005

• 융합신호처리학회논문지
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• 제24권2호
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• pp.90-96
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• 2023

합성곱 신경망을 비롯하여 딥러닝 신경망의 학습에서 많은 양의 훈련데이터의 확보는 과적합 현상을 피하고 우수한 성능을 가지기 위해서 매우 중요하다. 하지만, 딥러닝 신경망에서의 레이블화된 훈련데이터의 확보는 실제로는 매우 제한적이다. 이를 극복하기 위해, 이미 획득한 훈련데이터를 변형, 조작 등으로 추가로 훈련데이터를 생성하는 여러 증강 방법이 제안되었다. 하지만, 이미지, 문자 등의 훈련데이터와 달리, 인간 동작 인식을 행하는 합성곱 신경망의 생체신호 훈련데이터를 추가로 생성하는 증강 방법은 연구 문헌에서 찾아보기 어렵다. 본 연구에서는 합성곱 신경망에 기반한 인간 동작 인식을 위한 생체신호 훈련데이터를 생성하는 간편하지만, 효과적인 증강 방법을 제안한다. 본 연구의 제안된 증강 방법의 유용성은 추가로 생성된 생체신호 훈련데이터로 학습하여 합성곱 신경망이 인간 동작을 높은 정확도로 인식하는 것을 보임으로써 검증하였다.

• Interdisciplinary Bio Central
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• 제2권2호
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• pp.3.1-3.4
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• 2010

In the present research, we assessed the utility of the structural information of drugs for predicting human in vivo intrinsic clearance from in vitro intrinsic clearance data obtained by human hepatic microsome experiment. To compare with the observed intrinsic clearance, human intrinsic clearance values for 51 drugs were estimated by the classical methods using in vivo-in vitro scale-up and by the new methods using the in vitro experimental data and selected molecular descriptors of drugs by the forward selection technique together. The results showed that taking consideration of molecular descriptors into prediction from in vitro experimental data could improve the prediction accuracy. The in vitro experiment is very useful when the data can estimate in vivo data accurately since it can reduce the cost of drug development. Improvement of prediction accuracy in the present approach can enhance the utility of in vitro data.

• 대한전자공학회논문지TC
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• 제48권10호
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• pp.43-52
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• 2011

본 논문에서는 스마트 헬스케어 서비스를 위한 정책 기반 응급 생체 정보 구조를 제시한다. 제안된 서비스 구조를 통해 의료진이 원격지 환자의 응급 생체데이터를 빠르고 정확하게 모니터링 할 수 있다. 제안된 시스템은 생체 데이터 수집 및 전송 기능을 가진 IEEE 11073 표준 기반 에이전트와 매니저, IEEE 11073과 HL7 간 변환 기능 및 정책 기반의 자동 진단 기능을 가진 EMS (Emergency Management Server), HL7 표준 기반의 HL7 의료 시스템으로 크게 3 부분으로 구성한다. 마지막으로, 제안된 시스템을 구현함으로써 스마트 헬스케어 서비스에서 생체 데이터의 수집 및 응급 데이터 관리가 가능함을 보였다.

• Mycobiology
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• 제49권6호
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• pp.582-588
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• 2021

The interaction of mating pheromone and pheromone receptor from the B mating-type locus is the first step in the activation of the mushroom mating signal transduction pathway. The B mating-type locus of Lentinula edodes is composed of Bα and Bβ subloci, each of which contains genes for mating pheromone and pheromone receptor. Allelic variations in both subloci generate multiple B mating-types through which L. edodes maintains genetic diversity. In addition to the B mating-type locus, our genomic sequence analysis revealed the presence of a novel chromosomal locus 43.3 kb away from the B mating-type locus, containing genes for a pair of mating pheromones (PHBN1 and PHBN2) and a pheromone receptor (RCBN). The new locus (Bα-N) was homologous to the Bα sublocus, but unlike the multiallelic Bα sublocus, it was highly conserved across the wild and cultivated strains. The interactions of RcbN with various mating pheromones from the B and Bα-N mating-type loci were investigated using yeast model that replaced endogenous yeast mating pheromone receptor STE2 with RCBN. The yeast mating signal transduction pathway was only activated in the presence of PHBN1 or PHBN2 in the RcbN producing yeast, indicating that RcbN interacts with self-pheromones (PHBN1 and PHBN2), not with pheromones from the B mating-type locus. The biological function of the Bα-N locus was suggested to control the expression of A mating-type genes, as evidenced by the increased expression of two A-genes HD1 and HD2 upon the treatment of synthetic PHBN1 and PHBN2 peptides to the monokaryotic strain of L. edodes.

• 제어로봇시스템학회논문지
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• 제18권10호
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• pp.928-933
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• 2012

In this paper, the IR and compass sensors for the underwater system were used. The walls of the water tank have been recognized and avoided treating the walls as obstacles by the bio-mimetic underwater robot. This paper is consists of two parts: 1.The hardware part for the IR and compass sensors and 2.The software part for obstacle avoidance algorithm while the bio-mimetic robot is swimming with the obstacle recognition. Firstly, the hardware part controls through the RS-485 communications between a microcontroller and the bio-mimetic underwater robot. The software part is simulated for obstacle recognition and collision avoidance based upon the data from IR and compass sensors. Actually, the bio-mimetic underwater robot recognizes where is the obstacle as well as where is the bio-mimetic robot itself while it is moving in the water. While the underwater robot is moving at a constant speed recognizing the wall of water tank as an obstacle, an obstacle avoidance algorithm is applied for the wall following swimming based upon the IR and compass sensor data. As the results of this research, it is concluded that the bio-mimetic underwater robot can follow the wall of the water tank efficiently, while it is avoiding collision to the wall.