• Title/Summary/Keyword: Bio composite

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Inhibitory Effect on Angiotensin-converting Enzyme (ACE) and Optimization for Production of Ovotransferrin Hydrolysates (Ovotransferrin 가수분해물의 Angiotensin-converting Enzyme 활성억제 효과 및 생산 최적화)

  • Lee, Na-Kyoung;Ahn, Dong-Uk;Park, Keun-Kyu;Paik, Hyun-Dong
    • Food Science of Animal Resources
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    • v.30 no.2
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    • pp.286-290
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    • 2010
  • Angiotensin-converting enzyme (ACE) inhibitory activity and production optimization of ovotransferrin hydrolysates were studied. Ovotransferrin was hydrolyzed by several enzymes (protamex, alcalase, trypsin, pepsin, neutrase, and flavorzyme) and acid (0.03 N HCl). Ovotransferrin hydrolysate reduced ACE activity by 60.2%, 55.8%, and 42.6% when treated with trypsin, acid, and pepsin, respectively. Trypsin was selected for production of peptide having maximum AC inhibitory effect, which was greatest with 7 h hydrolysis. Central composite design determined that optimum composition of ACE inhibitory substances using substrate concentration of 20-35%, temperature of $35-55^{\circ}C$, and pH of 6.0-8.0. The optimum composition was 1% trypsin, substrate concentration of 26.32%, $51.29^{\circ}C$, and pH 6.32. Under this conditions, a maximum ACE inhibitory effect of 69.1% was evident, similar to the predicted value.

Bone Formation Effect of the RGD-bioconjugated Mussel Adhesive Proteins Composite Hydroxypropyl Methylcellulose Hydrogel Based Nano Hydroxyapatite and Collagen Membrane in Rabbits

  • Kim, Dong-Myong;Kim, Hyun-Cho;Yeun, Chang-Ho;Lee, Che-Hyun;Lee, Un-Yun;Lim, Hun-Yu;Chang, Young-An;Kim, Young-Dae;Choi, Sung-Ju;Lee, Chong-Suk;Cha, Hyung Joon
    • Journal of Marine Bioscience and Biotechnology
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    • v.7 no.2
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    • pp.58-70
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    • 2015
  • Injectable RGD-bioconjugated Mussel Adhesive Proteins (RGD-MAPs) composite hydroxypropyl methylcellulose (HPMC) hydrogels provide local periodontal tissue for bone filling in periodontal surgery. Previously we developed a novel type of injectable self-supported hydrogel (2 mg/ml of RGD-MAPs/HPMC) based porcine nano hydroxyapatite (MPH) for dental graft, which could good handling property, biodegradation or biocompatibility with the hydrogel disassembly and provided efficient cell adhesion activity and no inflammatory responses. Herein, the aim of this work was to evaluate bone formation following implantation of MPH and collagen membrane in rabbit calvarial defects. Eight male New Zealand rabbits were used and four circular calvarial defects were created on each animal. Defects were filled with different graft materials: 1) collagen membrane, 2) collagen membrane with MPH, 3) collagen membrane with bovine bone hydroxyapatite (BBH), and 4) control. The animals were sacrificed after 2 and 8 weeks of healing periods for histologic analysis. Both sites receiving MPH and BBH showed statistically increased augmented volume and new bone formation (p < 0.05). However, there was no statistical difference in new bone formation between the MPH, BBH and collagen membrane group at all healing periods. Within the limits of this study, collagen membrane with MPH was an effective material for bone formation and space maintaining in rabbit calvarial defects.

Effects of Hydrocolloids on Quality Characteristics of Bread with Rice Flour (쌀을 첨가하여 제조한 식빵의 품질 특성에 미치는 Hydrocolloids의 영향)

  • Kim, Yang-Hoon;Lee, Jeong-Hoon;Lee, Si-Kyung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.9
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    • pp.1324-1332
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    • 2016
  • The effects of different hydrocolloids, including hydroxypropyl methylcellulose (HPMC), xanthan gum (XG), guar gum (GG), and glucomannan (GM), on bread quality characteristics were investigated. The composite flour used for bread production consisted of 80% bread flour and 20% rice flour with 1% different hydrocolloids based on baker's%. Loaf volume, specific loaf volume, baking and cooling loss rate, moisture content, crumb texture and color, and sensory evaluation were determined. Breads containing HPMC and GM showed the highest loaf volumes, but the difference was not significant. Bread containing GM showed the lowest baking and cooling loss rate (7.03 and 7.78%, respectively), and the highest moisture content. Breads containing HPMC and GM showed increased springiness and decreased hardness based on texture profile analysis. Cohesiveness, chewiness, and gumminess of breads containing GM and HPMC showed their lowest values, whereas breads containing XG revealed their highest values. Bread with HPMC showed lightest coloured crumbs. In the sensory evaluation, bread containing GM and HPMC presented their highest scores, whereas bread containing XG showed the lowest scores. Overall, HPMC and GM significantly and positively affected quality characteristics of bread.

Antioxidant Properties of Acorn Hot-Water Extract Using Response Surface Methodology (반응표면 분석에 의한 도토리 열수 추출물의 항산화적 특성)

  • Lee, Jin-Man;Kim, Seong-Ho
    • Food Science and Preservation
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    • v.15 no.1
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    • pp.111-117
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    • 2008
  • As part of studies on functional food development from the acorn (Quercus acutissima CARRUTHERS), this study investigated the antioxidant properties of the acorn using response surface methodology. Optimal extraction conditions were established by monitoring total phenol levels, electron donating ability, antioxidant ability and nitrite-scavenging action using response surface analysis under a central composite design. The extraction temperature varied in the $30-70^{\circ}C$, the extraction time between 1-5 h, and the solvent ratio was in the interval 5-25mL/g of sample. Extracted total phenols were highest at $57.91^{\circ}C$, 4.08 h, and 22.39 mL/g. This extraction was influenced by solvent ratio, but not by extraction time or temperature. Electron donating ability was found to be highest at $60.37^{\circ}C$, 2.85h, and 6.47 mL/g. The highest antioxidant level was 2.09 AI at $37.11^{\circ}C$, 1.67 h, and 18.84 mL/g, and this value was greatly influenced by all of extraction temperature, extraction time, and solvent ratio. Nitrite-scavenging ability was found to be highest at $47.07^{\circ}C$, 1.24h, and 19.55mL/g. Changes in nitrite-scavenging ability were most influenced by solvent ratio, followed by extraction temperature, but no influence of extraction time within the range tested was found.

Factors Affecting Process Temperature and Biogas Production in Small-scale Rural Biogas Digesters in Winter in Northern Vietnam

  • Pham, C.H.;Vu, C.C.;Sommer, S.G.;Bruun, S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.7
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    • pp.1050-1056
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    • 2014
  • This study investigated the main factors influencing digester temperature and methods to reduce heat losses during the cold season in the subtropics. Four composite digesters (two insulated and two uninsulated) were buried underground to measure their internal temperature ($^{\circ}C$) at a depth of 140 cm and 180 cm, biogas production and methane ($CH_4$) concentration in biogas from August to February. In parallel the temperature of the air (100 cm above ground), in the slurry mixing tank and in the soil (10, 100, 140, and 180 cm depth) was measured by thermocouple. The influent amount was measured daily and the influent chemical composition was measured monthly during the whole experimental period. Seasonal variations in air temperature significantly affected the temperature in the soil, mixing tank and digester. Consequently, biogas production, which is temperature dependent, was influenced by the season. The main factors determining the internal temperature in the digesters were insulation with Styrofoam, air temperature and temperature of slurry in the mixing tank. Biogas production is low due to the cold climate conditions in winter in Northern Vietnam, but the study proved that storing slurry in the mixing tank until its temperature peak at around 14:00 h will increase the temperature in the digester and thus increase potential biogas production. Algorithms are provided linking digester temperature to the temperature of slurry in the mixing tank.

Evaluation of Gravity Ceramic Filter as Household Purifier: Using Clay & Red Soil in the Northwest of Cambodia (캄보디아 북서부 지역의 토양으로 제작된 정수용 중력식 필터 평가)

  • Kim, Younkwon;Kim, Sungpil;Cho, Wooseok;Hwang, Kwangtaek
    • Journal of Environmental Impact Assessment
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    • v.26 no.5
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    • pp.344-353
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    • 2017
  • Cambodia is a typical country that a very famous tourist destination in South Asian regions, but water has some serious problems. As a public hygiene point of view, water problems in Cambodia can be roughly classified into two categories. A numbers of the report revealed that thermotolerant coliform(TTC) bacteria and arsenic(As) pollution representative species as a representative pollutant for surface water and ground water problems, respectively. In recent years, home water purifier systems for various filter systems including BSF(Bio-Sand Filter), MF and RO have been spread and adopted in rural areas. However, BSF and composite membrane processes are recognized as an undesirable and representative method due to unreliable efficiency, high cost and maintenance issues. In order to develop a small-scale ceramic filter as a home water purifier, the applicability of two types of gravity ceramic filter using clay and red soil in the part of the Northwest was made and compared in this research.

S-value of Radioiodine($^{131}I$) in Korean Reference Adult Male (한국 성인남성 표준인을 대상으로 한 방사성옥소($^{131}I$)의 S-value 도출)

  • Kim, Jung-Hoon;Lim, Chang-Seon;Whang, Joo-Ho
    • Journal of radiological science and technology
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    • v.31 no.1
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    • pp.41-47
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    • 2008
  • In order to better understand the effects of absorbed radioiodine upon Korean reference adult male, a mathematical phantom representation was contrived based on composite data of the physiology of Korean reference adult male. Using this, S-values of radioiodine($^{131}I$) per each organ were calculated. The calculated S-values were compared to the existing data described in the TM-8381 report of ORNLcalculated on the basis of an ICRP-23 reference male. The results indicated that S-values were higher for the phantom based on Korean reference adult male. The results of this study illustrate that, while the bio-chemical constitution of each source and target organ of the torso are important, the relative location of the organs and characteristics of the radionuclides also exert important influences.

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Properties of Nano Silver-Silica Composite according to Changing Molecular Weight of PVP (PVP 분자량 변화에 따른 은-실리카 나노복합체의 특성에 관한 연구)

  • Son, Eun-Jong;Hwang, Young-Gu;Shin, Yu-Shik;Jung, Gi-Hoon;Jung, Hae-Rim;Jeong, Sung-Hoon
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2011.03a
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    • pp.55-55
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    • 2011
  • 실리카 지지체 위에 은 (silver) 나노 입자를 부착시키는 방법으로는 지지체 표면을 먼저 은입자와 친화성이 큰 amino(-NH2), mercapto(-SH), cyan(-CN) 등의 관능기로 표면처리 하는 방법이 일반적으로 사용된다. 구체적으로 설명하면 첫 단계로 지지체인 실리카입자의 표면을 아민으로 표면 처리 한다. 실리카 입자위에 부착된 아민관능기는 입자 생성의 단계에서 은 (silver) 나노 입자가 붙는 접촉점의 역할과 핵 생성 장소로서의 역할을 하게되고, 아민 관능기의 이런 역할로 실리카 입자 표면에 부착된 핵이 생장하여 입자가 됨으로써 최종적으로 은(silver) 나노 입자가 실리카 지지체위에 부착된 형태의 나노복합체가 형성된다. 분자량이 다른 PVP를 사용하여 제조한, NH2와 SH로 계면처리 된 은-실리카 나노복합체제조를 시도하였다. 사용되는 PVP의 분자량이 증가함에 따라 긴 고분자 사슬에 의하여 생성된 입체장애가 증가하게 되어, 은 핵의 성장에 대한 물리적 장벽이 증가하게 된다. 그러므로 고정화된 은 입자의 크기가 감소하게 된다. 이러한 형상은 NH2기 또는 SH기로 계면 처리된 실리카를 이용하여 제조된 은-실리카 나노복합체 입자들에서 모두 관찰되지만, SH기로 계면처리된 실리카를 사용할 경우 고정화된 은 입자의 수가 더욱 많고, 크기 역시 더욱 균일함을 알 수 있다.

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Determination of Wood Flour Content in WPC Through Thermogravimetic Analysis and Accelerator Mass Spectrometry (열중량 분석기와 질량가속기를 이용한 목재·플라스틱 복합재의 목질섬유함량 분석)

  • Gwon, Jae-Gyoung;Lee, Dan-Bee;Cho, Hye-Jung;Chun, Sang-Jin;Choi, Don-Ha;Lee, Sun-Young
    • Journal of the Korean Wood Science and Technology
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    • v.45 no.5
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    • pp.572-579
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    • 2017
  • Determination of the wood content in wood plastic composite (WPC) is crucial to form reliable WPC market. WPC with simple formulation consisting of only two components (wood flour and polypropylene) was examined using thermogravimetric analysis (TGA) and accelerator mass spectrometry (AMS) for determining wood content in the WPC. TGA method using derivative peak temperature (DTp) of polypropylene under low heating rate ($5^{\circ}C/min$) showed more reliable calibration curve and lower error factor compared to method of using the percentage of weight loss of wood flour. In addition, AMS using bio-based carbon content showed greater reliability for the determination of wood content in the WPC in comparison with the TGA method.

A Study on the Visual Perception Space Structure Analysis of Exhibition Contents Organization in Natural History Museum (자연사박물관 전시내용구성의 시지각적 공간구조분석에 관한 연구)

  • Kim, Eun-Jung;Hong, Kwan-Seon
    • Korean Institute of Interior Design Journal
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    • v.18 no.2
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    • pp.80-92
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    • 2009
  • Natural history museums preserve and manage the creatures living in each country, so they play unique roles for bio-diversity, and in fact, their roles are really instrumental for the collection, preservation, research, exhibition and education of creatures in the 21st century. Therefore, this research has the purpose to survey the status of our country's existing natural history museums, analyze their visual perception space structural characteristics, and ultimately utilize their characteristics as basic data in planning out and designing spaces of natural history museums to be established later on. As for the research scope, the research selected as research subjects 7 natural history museums that currently have composite set of open type and mixed type and have been accommodating comparatively active exhibitions since 2000 among 10 or so natural history museums in our country. Research method is that the research analyzed the exhibition spaces of 7 natural history museums by using depthmap program which can analyze space with visual graph analysis function, and analyzed the visibility among unit areas by each natural history museum integration and exhibition contents composition. In such analysis method, the research was able to quantitatively analyze the visual characteristics of exhibition space that induces and adjusts the motion of audience. Visual perception quantitative analysis as in this research will enhance exhibition design by considering the correlation between audience and exhibited items when planning out natural history museums space to be established later on.