• The Korean Journal of Food And Nutrition
• /
• v.35 no.6
• /
• pp.513-520
• /
• 2022

The purpose of this study was to investigate the effect of Cheonggukjang pills with aronia and blueberries on dextran sulfate sodium (DSS)-induced colitis in mice. There have been several reports that Cheonggukjang is effective for intestinal health, but the efficacy of Cheonggukjang containing fruits has not yet been reported. In this study, we showed the effect of cheonggukjang pills with blueberries and aronia (CPBA) on DSS-induced colitis in BALB/c mice. CPBA was obtained from Soonchang Moonokae foods and orally administered once a day for 2 weeks before DSS treatment. Colitis was induced in mice by feeding 5% (w/v) DSS drinking water for 7 days. The results showed that CPBA treatment significantly alleviated DSS-induced disease activity index associated with a decrease in colon length. CPBA improved DSS-induced histological changes and intestinal epithelial barrier integrity in mice colon. In addition, CPBA administration significantly reduced the levels of DSS-mediated interferon-γ and interleukin-6 in serum and tumor necrosis factor-α in colon tissue. Moreover, the gene expression of COX-2 and iNOS, which are factors involved in inflammatory signaling, was significantly reduced by CPBA treatment. These results suggest that CPBA have a protective effect against DSS-induced mice colitis and may be a candidate for colitis treatment.

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
• /
• 2011.04a
• /
• pp.157-167
• /
• 2011

• Proceedings of the Korean Society of Plant Pathology Conference
• /
• 2005.04a
• /
• pp.90.1-90.1
• /
• 2005

• 대한생식의학회:학술대회논문집
• /
• 2006.11a
• /
• pp.141-142
• /
• 2006

• Journal of Life Science
• /
• v.18 no.7
• /
• pp.931-939
• /
• 2008

The purpose of this study was to determine the effect of energy supplement on responses of plasma insulin-like growth factor (IGF)-1 and IGF binding proteins (IGFBPs) to growth hormone-releasing peptide-2 (GHRP-2) administration in normal protein-fed wethers, and to observe the effect of GHRP-2 treatment on hepatic growth hormone (GH) receptor in well-fed wethers. Plasma IGF-1 and 39-42 kDa IGFBP-3 during the HENP (CP, crude protein 0.34 and TDN, total digestible nutrients 1.83 kg/day DM, dry matter intake) treatment period were higher than in the LENP (CP 0.32 kg and TDN 0.87 kg/day DM intake) period (P<0.05). The response of GH was stimulated by GHRP-2 ($12.5\;{\mu}g/kg$ body weight/day) administration during both of the feed treatment periods (P<0.05). The area under curve (AUC) increment and average concentration of GH (0-180 min) with GHRP-2 administration was higher during HENP treatment than LENP treatment (P<0.01). During the HENP treatment period from day 1 to day 7 of twice daily GHRP-2 treatment, the plasma IGF-1 increment was increased on days 2, 6 and 7 of GHRP-2 administration (P<0.05). On the basis of ligand blotting, the proportions of plasma 39-43 kDa IGFBP-3 during the HENP treatment period only showed a significant difference on days 6 and 7 with GHRP-2 administration. No significant difference in the specific binding of $^{125}I-labeled$ oGH to hepatic membranes was detected between the saline and GHRP-2 treatments of the HENP-fed wethers. These results suggest that the nutritional balance between energy and protein may affect the endogenous GH / IGF-1 axis as well as plasma IGFBP-3 levels.

• Journal of the Korean Applied Science and Technology
• /
• v.22 no.1
• /
• pp.21-27
• /
• 2005

This study was conducted to evaluate the biofiltration treatment characteristic for benzene vapor gas. Compost and calcium silicate porous material were used as biofilter fillers. Gas velocity and empty bed retention time were 15 m/hr and 4 min, respectively. Benzene gas removal efficiency of P-Bio (calcium silicate porous material with inoculation) was the highest and maintained in over 98%. After shock input of benzene gas, the removal efficiency of P-Bio biofilter was recovered within 2 days, while 5 days were taken in CP-Bio (compost + calcium silicate porous material mixture with inoculation) and CP (compost + calcium silicate porous material mixture without inoculation) biofilters. The removal efficiency of P-Bio biofilter was near 100% in the loading rate of <$85g/m^3$(filling material)/hr, It was shown that the maximum elimination capacities of P-Bio, CP-Bio, and CP biofilters were 95, 69, and $66\;g/m^3$(filling material)/hr, respectively. Microbial number of P-Bio, which the number was the lowest at start-up, was 3 orders increased on operational day 48. $CO_2$ was generated greatly in order of P-Bio, CP-Bio, and CP biofilters.

• Journal of Ginseng Research
• /
• v.39 no.4
• /
• pp.365-370
• /
• 2015

Background: The beneficial effects of ginsenoside species have been well demonstrated in a number of studies. However, the function of ginsenoside Ro (GRo), an oleanane-type saponin, has not been sufficiently investigated. Thus, the aim of the present study was to investigate the anti-inflammatory effects of GRo in vitro using the Raw 264.7 mouse macrophage cell line treated with lipopolysaccharide (LPS), and to clarify the possible mechanism of GRo involving heme oxygenase-1 (HO-1), which itself plays a critical role in self-defense in the presence of inflammatory stress. Methods: Raw 264.7 cells were pretreated with GRo (up to $200{\mu}M$) for 1 h before treatment with 1 mg/mL LPS, and both cell viability and inflammatory markers involving HO-1 were evaluated. Results: GRo significantly increased cell viability in a dose dependent manner following treatment with LPS, and decreased levels of reactive oxygen species and nitric oxide. GRo decreased inflammatory cytokines such as nitric oxide synthase and cyclooxygenase-2 induced by LPS. Moreover, GRo increased the expression of HO-1 in a dose dependent manner. Cotreatment of GRo with tin protoporphyrin IX, a selective inhibitor of HO-1, not only inhibited upregulation of HO-1 induced by GRo, but also reversed the anti-inflammatory effect of GRo in LPS treated Raw 264.7 cells. Conclusion: GRo induces anti-inflammatory effects following treatment with LPS via upregulation of HO-1.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.27 no.4
• /
• pp.481-486
• /
• 2013

To investigate the effects of facial temperature and blood flow rates generated by Miso Facial Rejuvenation Acupuncture treatment. Ten women in their twenties to fifties with no skin diseases were recruited. Miso Facial Rejuvenation Acupuncture(MFRA) was performed on the both sides of their face. We measured their facial temperature using Digital Infrared Thermal Imaging(DITI) and blood flow rates using Laser Doppler Perfusion Imaging(LDPI) at pre-treatment, immediately, twenty and sixty minutes after treatment. We analyzed data using student's t-test(p<0.05). After MFRA treatment, facial temperature on the measurement area increased immediately from $30.5{\pm}1.0^{\circ}C$ to $31.5{\pm}1.0^{\circ}C$, a statistically significant increase. Sixty minutes after treatment, facial temperature on the measurement area decreased a little bit($30.2{\pm}0.6^{\circ}C$), but there was no statistical significance. After MFRA treatment, facial blood flow rates on the measurement area increased immediately from $165.1{\pm}52.3$ PU to $342.7{\pm}51.3$ PU, a statistically significant increase. Sixty minutes after treatment, facial blood flow rates measurement area were recovered almost at the same level as before treatment. MFRA treatment could increase facial temperature and blood flow rates.

• Korean Journal of Soil Science and Fertilizer
• /
• v.20 no.2
• /
• pp.169-177
• /
• 1987

Effect of microbiological product manure (Bio-com) on the growth and yield of vegetables and on physico-chemical properties of soil. Leaf lettuce and Garland Chrysanthemum were taken for test plants. A Jungdong (Series) silty loam soil was used for pot experiments. The results are summarized as following: 1. Treatment with Bio-com stimulated plant growth that were increased in the number of leaf, leaf area, plant height and root length both for Leaf lettuce and Garland Cyrysanthemum. 2. Yield increase of 123-1170% was obtained from Bio-com treatments compared to N.P.K.+manure treatment. Application of 2250 kg/10a of Bio-com gave the highest yield. 3. Fertilizer effect of Bio-com appeared much earlier than that of manure. 4. Plant content of $K_2O$ was highest when treated with Bio-com. Plants absorbed considerably more N, $P_2O_5$ and MgO. 5. Content of N, $P_2O_5$ in Garland Chrysanthemum were higher when treated with Bio-com. 6. Content of $P_2O_5$ in soil was at the highest level. Soil pH, content of exchangeable soil Ca and Mg were also high with Bio-com fertilization.

• Journal of Korea Technical Association of The Pulp and Paper Industry
• /
• v.45 no.3
• /
• pp.27-35
• /
• 2013

Cotton linter pre-treatment methods using electron beam and sulfuric acid were investigated to prepare high quality regenerated fibers for fabrics. So far, NaOH was used to reduce the degree of polymerization (DP) of the cotton linter for ease of dissolving by cellulose solvent. Two pre-treatment methods were developed to reduce the consumption of the chemicals (NaOH) and to control the DP of cellulose more precisely. Changes in ${\alpha}$-cellulose contents and brightness by the pre-treatments were also important concerns. Both electron beam irradiation and sulfuric acid were shown to be effective on controlling the DP of cellulose and to reduce the chemical consumption, but reduced ${\alpha}$-cellulose contents as well in this study. Sulfuric acid pre-treatment, which needed additional washing process after the pre-treatment when comparing to the electron beam irradiation method, gave the highest brightness and the highest reduction of ${\alpha}$-cellulose content.