• Title/Summary/Keyword: Bio Sensors

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A Temperature-Controllable Microelectrode and Its Application to Protein Immobilization

  • Lee, Dae-Sik;Choi, Hyoung-Gil;Chung, Kwang-Hyo;Lee, Bun-Yeoul;Pyo, Hyeon-Bong;Yoon, Hyun-C.
    • ETRI Journal
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    • v.29 no.5
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    • pp.667-669
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    • 2007
  • This letter presents a smart integrated microfluidic device which can be applied to actively immobilize proteins on demand. The active component in the device is a temperature-controllable microelectrode array with a smart polymer film, poly(N-isopropylacrylamide) (PNIPAAm) which can be thermally switched between hydrophilic and hydrophobic states. It is integrated into a micro hot diaphragm having an integrated micro heater and temperature sensors on a 2-micrometer-thick silicon oxide/silicon nitride/silicon oxide (O/N/O) template. Only 36 mW is required to heat the large template area of 2 mm${\times}$16 mm to $40^{\circ}C$ within 1 second. To relay the stimulus-response activity to the microelectrode surface, the interface is modified with a smart polymer. For a model biomolecular affinity test, an anti-6-(2, 4-dinitrophenyl) aminohexanoic acid (DNP) antibody protein immobilization on the microelectrodes is demonstrated by fluorescence patterns.

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Cytidine Biosensor Using Bacteria and Organelle (Bacteria 및 Organelle을 이용한 Cytidine Biosensor)

  • Ihn, Gwon Shik;Kim Jeong-Suk;Jeon Young Guk;Kim Bong Weon
    • Journal of the Korean Chemical Society
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    • v.35 no.1
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    • pp.38-45
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    • 1991
  • The cytidine bio-sensors have been constructed by immobilizing the bacterium Proteus mirabilis and organelle on an ammonia gas sensor. The bacterial sensor was investigated for the effects of pH, temperature, buffer solution, bacterial amounts, interferences and lifetime. The bacterial sensor had linearity in the range of 5.0 ${\times}$ 10$^{-4}$M ∼ 1.0 ${times}$ 10$^{-2}$M cytidine with a slope of 56 mV/decade at pH 7.8, 30$^{\circ}C$ and 3 mg in 1.0 M phosphate buffer solution. This bacterial sensor was compared with it's organelle sensor.

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Application of Hybrid Polymeric Complexes to Solid State and Materials Chemistry

  • Josik Portier;Guy Campet;Nadine Treuil;Armel Poquet;Kim, Young Il;Kwon, Soon Jae;Kwak, Seo Young;Choy, Jin Ho
    • Journal of the Korean Chemical Society
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    • v.42 no.4
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    • pp.487-500
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    • 1998
  • A bird's-eye view on preparation, structure and properties of polymeric complexes in the field of Inorganic-Organic-Hybrids is presented in the view point of solid state and materials chemistry. These materials are useful precursors for preparing nanoparticles and fine grain oxides. Some of them are electroactive and are used as protonic or lithium electrolytes, electrochromic materials or membranes for sensors and actuators. New results on bio-hybrids, a class of material not far from polymeric complexes, are also described.

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Study on Integrated Monitoring System for Protecting Water Pollution (수질오염 방지를 위한 통합 모니터링 시스템에 관한 연구)

  • Yang, Jae-Soo;Kim, Yoon-Hyun;Han, Yong-Hwan;Lee, Young-Ha;Kim, Jin-Young
    • KSBB Journal
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    • v.26 no.5
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    • pp.412-416
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    • 2011
  • The conventional monitoring system for water pollution measurement is quite simple and independent and it has a lot of draw backs such as cost, installation, etc. So, in this paper, we have measured the water pollution system through a bacterial species, photobacterium phosphoreum. A novel integrated monitoring system technology has been developed which could easily dictate and analyze the major water pollutants and its surrounding environment in an accurate way. The system constitutes of bionic technology, information technology and environmental engineering technology. As a result, integrated monitoring system can observe the water pollution and various water environment of the whole country. Also, through the sensors of USN, Zigbee, RFID and middle ware, which can provide service and construct service platform, a properly standardized plan with remarkable service platform has been established through this investigation.

A Study on Gel-free Probe for Detecting EEG (뇌파 탐지용 Gel-free probe 연구)

  • Yun, Dae-Jhoong;Eum, Nyeon-Sik;Jeong, Myung-Yung
    • Journal of Sensor Science and Technology
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    • v.21 no.2
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    • pp.156-166
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    • 2012
  • Over the past 15 years productive BCI research programs have arisen. Current mainstream EEG electrode setups permit efficient recordings but most of electrodes has the disadventages of need for skin preparation and gel application to correctly record signals. The new gel-free probe was adapted for EEG recording and it can be fixed to the scalp with the micro needle without neuro-gel. It use standard EEG cap for wearing electrodes on scalp so it is compatible with standard EEG electrodes. A comparison between electrode characteristics is achieved by performing simultaneous recordings with the gel electrodes and gel-free probe placed in parallel scalp positions on the same anatomical regions. The quality of EEG recordings for all two types of experimental conditions is similar for gel-electrodes and gel-free probe. Subjects also reported not having special tactile sensations associated with wearing of gel-free probes. According to our results, it is expected that gel-free probe can be adapted to BCI, BMI(Brain Machine Interface), HMI(Human Machine Interface) because of its simple application and comfortable wearing process.

Exploring Image Processing and Image Restoration Techniques

  • Omarov, Batyrkhan Sultanovich;Altayeva, Aigerim Bakatkaliyevna;Cho, Young Im
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.15 no.3
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    • pp.172-179
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    • 2015
  • Because of the development of computers and high-technology applications, all devices that we use have become more intelligent. In recent years, security and surveillance systems have become more complicated as well. Before new technologies included video surveillance systems, security cameras were used only for recording events as they occurred, and a human had to analyze the recorded data. Nowadays, computers are used for video analytics, and video surveillance systems have become more autonomous and automated. The types of security cameras have also changed, and the market offers different kinds of cameras with integrated software. Even though there is a variety of hardware, their capabilities leave a lot to be desired. Therefore, this drawback is trying to compensate by dint of computer program solutions. Image processing is a very important part of video surveillance and security systems. Capturing an image exactly as it appears in the real world is difficult if not impossible. There is always noise to deal with. This is caused by the graininess of the emulsion, low resolution of the camera sensors, motion blur caused by movements and drag, focus problems, depth-of-field issues, or the imperfect nature of the camera lens. This paper reviews image processing, pattern recognition, and image digitization techniques, which will be useful in security services, to analyze bio-images, for image restoration, and for object classification.

Optimization of Manufacturing Conditions of Pressure-Sensitive Ink Based on MWCNTs (MWCNTs 기반 인쇄형 압력감응잉크의 제조 조건 최적화)

  • Park, Sung-Chul;Lee, In-Hwan;Bae, Yong-Hwan;Kim, Ho-chan
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.18 no.8
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    • pp.1-7
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    • 2019
  • Materials that can be used for 3D printing have been developed in terms of phase and functionality. Materials should also be easily printed with high accuracy. In recent years, the concept of 4D printing has been extended to materials whose physical properties such as shape or volume can change depending on the environment. Typically, such high-performance 3D printing materials include bio-inks and inks for sensors. This study deals with the optimization of the manufacturing method to improve the functional properties of the pressure sensitive material, which can be used as a sensor based on change of the resistance according to the pressure. Specifically, the number of milling for dispersion, the ratio of hardener for controlling elasticity, and the content of MWCNTs were optimized. As a result, a method of manufacturing a highly sensitive pressure-sensitive ink capable of use in 3D printing was introduced.

Measurement of Apnea Using a Polyvinylidene Fluoride Sensor Inserted in the Pillow (베게에 삽입된 PVDF센서를 이용한 무호흡증 측정)

  • Keum, dong-Wi;Kim, Jeong-Do
    • Journal of Sensor Science and Technology
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    • v.27 no.6
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    • pp.407-413
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    • 2018
  • Most sleep apnea patients exhibit severe snoring, and long-lasting sleep apnea may cause insomnia, hypertension, cardiovascular diseases, stroke, and other diseases. Although polysomnography is the typical sleep diagnostic method to accurately diagnose sleep apnea by measuring a variety of bio-signals that occur during sleep, it is inconvenient as the patient has to sleep with attached electrodes at the hospital for the diagnosis. In this study, a diagnostic pillow is designed to measure respiration, heart rate, and snoring during sleep, using only one polyvinylidene fluoride (PVDF) sensor. A PVDF sensor with piezoelectric properties was inserted into a specially made instrument to extract accurate signals regardless of the posture during sleep. Wavelet analysis was used to identify the extractability and frequency domain signals of respiration, heart rate, and snoring from the signals generated by the PVDF sensor. In particular, to separate the respiratory signal in the 0.2~0.5 Hz frequency region, wavelet analysis was performed after removing 1~2 Hz frequency components. In addition, signals for respiration, heart rate, and snoring were separated from the PVDF sensor signal through a Butterworth filter and median filter based on the information obtained from the wavelet analysis. Moreover, the possibility of measuring sleep apnea from these separated signals was confirmed. To verify the usefulness of this study, data obtained during sleeping was used.

Design and Implementation of a Mobile-based Sarcopenia Prediction and Monitoring System (모바일 기반의 '근감소증' 예측 및 모니터링 시스템 설계 및 구현)

  • Kang, Hyeonmin;Park, Chaieun;Ju, Minina;Seo, Seokkyo;Jeon, Justin Y.;Kim, Jinwoo
    • Journal of Korea Multimedia Society
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    • v.25 no.3
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    • pp.510-518
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    • 2022
  • This paper confirmed the technical reliability of mobile-based sarcopenia prediction and monitoring system. In implementing the developed system, we designed using only sensors built into a smartphone without a separate external device. The prediction system predicts the possibility of sarcopenia without visiting a hospital by performing the SARC-F survey, the 5-time chair stand test, and the rapid tapping test. The Monitoring system tracks and analyzes the average walking speed in daily life to quickly detect the risk of sarcopenia. Through this, it is possible to rapid detection of undiagnosed risk of undiagnosed sarcopenia and initiate appropriate medical treatment. Through prediction and monitoring system, the user may predict and manage sarcopenia, and the developed system can have a positive effect on reducing medical demand and reducing medical costs. In addition, collected data is useful for the patient-doctor communication. Furthermore, the collected data can be used for learning data of artificial intelligence, contributing to medical artificial intelligence and e-health industry.

A Study on the Field Application and Prospect of Artificial Intelligence and Bio-Sensing Technology in Physical Therapy: Focusing on Customized Rehabilitation Treatment (물리치료 분야에서 인공지능 및 바이오센싱 기술의 현장적용 및 전망에 관한 연구: 맞춤형 재활치료를 중심으로)

  • Kyung-Tae Yoo
    • Journal of the Korean Society of Physical Medicine
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    • v.18 no.3
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    • pp.73-84
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    • 2023
  • PURPOSE: This study analyzed the impact of AI and biosensors on physical therapy, identifying the stage of customized technology development and future prospects. AI and biosensors improve the efficiency, establish customized treatment plans, and expand patient treatment opportunities. The study employed a literature review by searching databases and collecting research. METHODS: This study searched various databases related to the topic, collected existing research, papers, and reports, evaluated the literature, and summarize the results. RESULTS: Exercise therapy utilizing artificial intelligence can provide personalized and optimal exercise plans while monitoring rehabilitation progress. In addition, biosensors such as EMG sensors and accelerometers can monitor the individual progress in physical therapy, particularly in stroke patients, which can help improve physical therapy strategy and promote patient recovery. CONCLUSION: This study suggested that artificial intelligence can be applied in many areas of physical therapy, such as exercise therapy, customized treatment plans, rehabilitation and management, pain management, neuro rehabilitation, and auxiliary devices. Using AI technology, it is possible to analyze and improve exercise and posture, retrain the central nervous system, establish customized treatment plans for individual patients, predict and compare patient progress before and after treatment, and provide customized pain analysis and treatment methods. In addition, AI can provide neuro rehabilitation programs and customized auxiliary devices.