• Title/Summary/Keyword: Bio Plant

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[ $\alpha$ ]-Glucosidase Inhibitors from the Roots of Codonopsis lanceolata Trautv

  • Jung, Suk-Whan;Han, Ae-Jin;Hong, Hae-Jin;Choung, Myoung-Gun;Kim, Kwan-Su;Park, Si-Hyung
    • Journal of Applied Biological Chemistry
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    • v.49 no.4
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    • pp.162-164
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    • 2006
  • The roots of Codonopsis lanceolata afforded tangshenoside I(1) and $\beta$-adenosine (2) as $\alpha$-glucosidase inhibitors. Their structures were unambiguously determined by 1D and 2D NMR data including HMQC and HMBC experiments. Compounds 1 and 2 exhibited weak $\alpha$-glucosidase inhibitory activities in vitro with $IC_{50}$ of 1.4 and 9.3 mM, respectively.