• 제목/요약/키워드: Bio Industry

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보름달물해파리 추출물의 항노화 효과 (Anti-aging effects from extracts of Aurelia aurita)

  • 서효현;조문진;이진형;이정훈;김소정;이건섭;이택견;모상현
    • 한국산학기술학회:학술대회논문집
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    • 한국산학기술학회 2012년도 춘계학술논문집 1부
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    • pp.274-277
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    • 2012
  • 지구온난화의 폐해 중 하나인 해파리의 대량증식은 환경 생태계에 좋지 않은 영향을 미치고 있고, 또한 과도한 개체수는 원할한 처리가 곤란해 많은 문제점을 초래하고 있는 실정이다. 이러한 해파리의 생산적이고 효율적인 개선방안으로 단순 가공식품 뿐만 아니라 해파리의 추출을 통해 산업적으로 활용가능한 기능성 화장품원료로의 응용가능성도 고려해 볼 수 있을 것이다. 따라서 본 연구는 보름달물 해파리 유래 추출물의 기능성 화장품 원료로서의 안전성 및 유효성을 규명하였다. 인간피부섬유아세포에서의 세포독성, 주름 개선 효과와 관련된 procollagen 발현양의 증가 및 노화로 증가되는 SA-${\beta}$-Gal 효소의 활성을 염색을 통하여 확인하였고, 항노화 화장품 신소재로서의 사업화 가능성을 확인 할 수 있었다.

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해양바이오에너지 개발사업의 경제적 파급효과 (The Economic Impacts of Marine Bio-energy Development Project)

  • 김태영;진세준;박세헌;표희동
    • 에너지공학
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    • 제22권2호
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    • pp.184-196
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    • 2013
  • 경제 발전과 산업의 발달로 화석연료를 대체할 신재생에너지 개발의 필요성이 대두되고 있다. 환경과 에너지 문제를 동시에 해결할 수 있는 에너지 개발이 필수적이며, 그 대안으로 해양 미생물에 기초한 신재생에너지 개발이 해결방법으로 떠오르고 있다. 정부의 제3차 신 재생에너지 기술개발 및 이용 보급 계획에 근거하여, 2030년까지 바이오에너지 부분의 50%인 500만TOE를 해양 바이오에너지에서 생산하려 한다. 본 연구는 국가 경제에서 해양바이오에너지 개발사업이 국내 경제에 미치는 파급효과에 대하여 산업연관분석을 적용하여 분석하고자 한다. 생산유발, 부가가치 유발, 취업유발에 미치는 효과 및 연구개발 유발효과 4가지를 분석하되, 수요유도형 모형을 적용한 분석 결과를 제시한다. 한국은행 산업연관표 기본부문 기준 403부문 중에서 66개 부문을 해양 바이오에너지 관련 부문이라 정의한 후, 해양바이오에너지 관련 부문을 중심에 놓고 이를 외생화하여 분석한다. 해양바이오에너지 개발사업에 2,234억원의 예산이 투입되면, 생산유발효과 3,123억원, 부가가치 유발효과 865억원, 취업유발효과 1,151명, 연구개발 유발효과 47.8억원으로 분석되었다. 이러한 정량적 정보는 해양바이오에너지 개발사업의 상용화에 대한 정책 결정에 활용될 수 있다.

물리화학적 처리에 의한 린터의 결정성 변화에 관한 연구 (Cotton Linter Crystallinity Variations Caused by Electron Beam Irradiation and Acid Treatment)

  • 박희정;손하늘;서영범
    • 펄프종이기술
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    • 제46권4호
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    • pp.37-43
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    • 2014
  • The crystallinity and molecular weight of cotton linter need to be controlled to be more easily dissolved in NMMO during manufacture of clothing fabrics. Electron beam irradiation and sulfuric acid treatment were used as pre-treatment to reduce molecular weight of cotton linter more efficiently, and after the pre-treatment, peroxide bleaching was followed in alkaline condition. After those processes, the crystalline indices of the cotton linters were measured by XRD method, and other properties such as their alpha cellulose contents and degree of polymerization were measured. It was found that the crystallinity index of cotton linter was decreased as the irradiation of electron beam increased while increased as the dose of sulfuric acid increased. These results strongly suggested that electron beam damaged the crystalline structure of the cellulose directly while sulfuric acid dissolved mostly non-crystalline area of the cellulose structure.

Effect of PFI mill and Valley beater refining on cellulose degree of polymerization, alpha cellulose contents, and crystallinity of wood and cotton fibers

  • Hai, Le Van;Park, Hee Jung;Seo, Yung Bum
    • 펄프종이기술
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    • 제45권4호
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    • pp.27-33
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    • 2013
  • Manufacturing fabrics from dissolving cellulosic pulp is increasing in these days. For making high quality of cellulose-based fabrics, control of cellulose DP (degree of polymerization), its alpha cellulose content, its brightness, and its crystallinity are important. To process the cellulosic raw material, refining of cellulosic fibers is essential, and it is important to know if refining affects those important cellulose properties. The effects of PFI mill and Valley beater refining on the alpha-cellulose content, cellulose DP, crystallinity, and paper mechanical properties of wood and two different cotton fibers were studied. The results showed that PFI mill refining rarely affected those properties. Fibers refined by a Valley beater displayed a small reduction in fiber length in comparison with those refined by a PFI mill. However, the Valley beater refining method produced almost no changes in cellulose properties, either. The refining process seemed to have very little effect on the cellulose DP, crystallinity index, or alpha-cellulose content until the freeness decreased to around 300 mL CSF for wood and 100 mL CSF for cotton fibers, respectively. There were also no differences in tensile strength development in two refining methods.

자주식 동력운반장치를 이용한 농산물 수확·운반작업의 편이성 및 생산성 분석 -경북지역의 과채류 재배농가 조사연구- (Analysis of Convenience and Productivity of Harvesting·Transporting Farm Products with Self-propelled Power Transportation Devices -Reference on Fruit Vegetable Farms in Gyeongbuk Region-)

  • 하유신;손철민;남상헌;김진현
    • 한국산업융합학회 논문집
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    • 제14권1호
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    • pp.29-36
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    • 2011
  • This study analyzed the convenience and productivity before and after adopting self-propelled power transportation devices to the harvest and transportation of fruit and vegetable products in the Gyeongbuk region, by applying the REBA and RULA techniques. In the REBA analysis, the work risk was low with 4~6 points before adoption which became 2~3 points after adoption. As for the RULA analysis, work loading appeared to have decreased with 6~7 points before adoption which became 3~4 points after adoption. The annual work time reduction was about 48~179 hours while labor costs were reduced to 364~1,345 thousand won annually. This indicated a labor cost reduction effect of about 10~15%. Therefore, the adopted self-propelled power transportation devices appeared to prevent musculo skeletal diseases of the human body and also improve productivity even after using it for long hours according to the REBA, RULA measures level.

IT용 초소형부품의 불량검출과 산업현장의 재해방지 효과 (The Effect of Disaster Prevention of Industrial Field and Failure Detection of Very Small Components for IT)

  • 박대영;정양근;최선미;변재영;최원식
    • 한국산업융합학회 논문집
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    • 제18권1호
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    • pp.18-29
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    • 2015
  • This paper presents a feasibility study of a fresh air load reduction system by using an underground double floor space. The system was introduced into a real building and was examined by the field measurement. Judging from the measurements during three years(1999~2001), the state of the system operation was very stable through this period and it was clear that the system contributes to reduction of energy consumption for air-conditioning. Futhermore, a simulation model used the simple heat diffusion equation was developed to simulate its thermal characteristics and performances. The simulations resulted in air temperature in good agreement with the measurements. Also, from the result of numerical analysis, it is clear that the amount of heat supply by using this system is more than the amount of energy loss to the room above it. Therefore, it is concluded that this systems is very useful and the proposed numerical model can be used for the prediction of system thermal performance.

탄산칼슘 적용에 의한 KOCC 지필의 고형분 증대 (Use of Calcium Carbonate for Improving Solid Content of KOCC Wet Web)

  • 황인영;지성길;서영범
    • 펄프종이기술
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    • 제45권6호
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    • pp.1-9
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    • 2013
  • For the manufacture of linerboard with 100% KOCC, we tried to increase the solid content of wet web by employing GCC (grounded calcium carbonate) in the fiber furnish to save drying energy. Three different diameters of GCC, namely, 5, 10, and $35{\mu}m$, were used. To complement the strength loss by the addition of GCC, cationic starch and refining treatment were tried. It was found that the addition of $10-35{\mu}m$ dia. GCC to KOCC for $180g/m^2$ basis weight sheets increased the solid content of the furnish about 1-1.5% with better bulk and drainage properties. The loss of strength properties were compensated by the application of cationic starch and/or refining process to the KOCC furnish. The dia. of GCC of $35{\mu}m$ was, however, too large to make smooth surface of the sample sheet. So, the optimization process was required before implementing the results to the mill by selecting proper diameter and shape of the calcium carbonate.

Sinapic Acid Attenuates the Neuroinflammatory Response by Targeting AKT and MAPK in LPS-Activated Microglial Models

  • Tianqi Huang;Dong Zhao;Sangbin Lee;Gyochang Keum;Hyun Ok Yang
    • Biomolecules & Therapeutics
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    • 제31권3호
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    • pp.276-284
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    • 2023
  • Sinapic acid (SA) is a phenolic acid that is widely distributed in fruits and vegetables, which has various bioactivities, such as antidiabetic, anticancer and anti-inflammatory functions. Over-activated microglial is involved in the development progress of neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease. The objective of this study was to investigate the effect of SA in microglia neuroinflammation models. Our results demonstrated that SA inhibited secretion of the nitric oxide (NO) and interleukin (IL)-6, reduced the expression of inducible nitric oxide synthase (iNOS) and enhanced the release of IL-10 in a dose-dependent manner. Besides, our further investigation revealed that SA attenuated the phosphorylation of AKT and MAPK cascades in LPS-induced microglia. Consistently, oral administration of SA in mouse regulated the production of inflammation-related cytokines and also suppressed the phosphorylation of MAPK cascades and AKT in the mouse cerebral cortex. These results suggested that SA may be a possible therapy candidate for anti-inflammatory activity by targeting the AKT/MAPK signaling pathway.

포공영의 열수 및 에탄올 추출물의 기능적 생리활성 (Functional Biological Activity of Hot Water and Ethanol Extracts from Taraxaci Herba)

  • 임애경;김정옥;정미정;정희경;홍주헌;김대익
    • 한국식품영양과학회지
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    • 제37권10호
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    • pp.1231-1237
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    • 2008
  • 포공영의 총 페놀함량에서는 열수 추출물 7.80$\pm$0.97 mg/g, 에탄올 추출물 9.12$\pm$0.51 mg/g으로 나타났다. 플라보노이드함량은 열수 추출물 54.20$\pm$1.95 mg/g, 에탄올 추출물 79.43$\pm$4.44 mg/g으로 항산화 활성에 관련된 페놀 및 플라보노이드 화합물들이 에탄올 추출물에 많이 존재함을 확인할 수 있었다. 전자공여능에 있어서도 포공영 에탄올 추출물이 열수 추출물 $IC_{50}$값에 비해 3배 정도의 뛰어난 활성을 보였다. 아질산염 소거능은 모든 pH 조건하에서 에탄올 추출물이 열수 추출물보다 높은 아질산염 소거능을 나타내었으며, pH가 증가할수록 감소하였다. SOD 유사활성을 측정한 결과 열수 추출물에서는 18.34$\sim$37.26 $\mu$g/mL, 에탄올 추출물에서는 16.60$\sim$49.03 $\mu$g/mL의 범위로 분석되었으며, 농도에 따른 유의적 증가현상을 나타내었다. Tyrosinase 및 elastase 저해활성은 모든 추출물에서 대조구에 비해 다소 약한 활성을 나타내었다. 포공영 추출물은 뛰어난 항산화 활성을 나타나 기능성 식품 및 화장품 소재로 개발 가능성이 높을 것으로 사료된다.