• 제목/요약/키워드: Bi-stable

검색결과 208건 처리시간 0.024초

Preformulation Study of Prokidin : Chemical Stability

  • Lee, Yun-Jin;Chun, In-Koo
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 2001년도 추계학술대회 및 정기총회
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    • pp.88-88
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    • 2001
  • The effects of pH and temperature on the degradation of prokidn in various buffered aqueous solutions(pH 1.32~9.66) and temperatures (35, 45 and 6$0^{\circ}C$ were investigated. The effect of ionic strength on the degradation of prokidin was also measured by varying ionic strength (0.0466~1.5) at pH 1.35 and 45$^{\circ}C$ The effect of metal ions on the degradation of prokidin at pH 7.35 and 3.98 was observed. The degradation of prokidin followed the pseudo- first- order kinetics. The degradation rate of prokidin showed pH-dependent and temperature-dependent patterns. Prokidin was very stable at the pH below 3.95, where half-lives at 35, 45 and 6$0^{\circ}C$were 294, 206 and 107 day, respectively. However, it degraded very rapidly at pH above 6.49; the half-lives at 35, 45 and 6$0^{\circ}C$were 60, 25 and 13 day, respectively. As ionic strength increased, the degradation rate of prokidin increased. Some metal ions increased the degradation rate in the rank order of Mn > Fe > Cu >Fe On the other hand. other metal ions such as Bi, Ba. Zn, Ni, Co did not show unfavorable effect.

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비정렬 유한체적법을 이용한 유동장 내의 연료액적 증발 특성 해석 (Unstructured Finite-Volume Analysis of Vaporization Characteristics of Fuel Droplets in Laminar Flow Field)

  • 김태준;김용모;손정락
    • 한국분무공학회지
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    • 제5권1호
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    • pp.13-22
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    • 2000
  • The present study has numerically analyzed the vaporization characteristics of fuel droplets in the high temperature convective flow field. The axisymmetric governing equations for mass, momentum, energy, and species are solved by an iterative and implicite unstructured finite-volume method. The moving boundary due to vaporization is handled by the deformable unstructured grid technique. The pressure-velocity coupling in the density-variable flows is treated by the SIMPLEC algorithm. In terms of the matrix solver, Bi-CGSTAB is employed for the numerically efficient and stable convergence. The n-decane is used as a liquid fuel and the initial droplet temperature is 300K. Computations are performed for the nonevaporating and evaporating droplets with the relative interphase velocity(25m/s). The unsteady vaporization process has been simulated up to the nondimensional time, 25. Numerical results indicate that the mathematical model developed in this study succesfully simulates the main features of the droplet vaporization process in the convective environment.

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Production of Useful Proteins by Plant Cell Culture

  • Kwon, Tae-Ho;Kim, Dae-Hyun;Jang, Yong-Suk;Yang, Moon-Sik
    • 한국식물학회:학술대회논문집
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    • 한국식물학회 1999년도 제13회 식물생명공학심포지움 New Approaches to Understand Gene Function in Plants and Application to Plant Biotechnology
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    • pp.45-49
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    • 1999
  • Plant cell culture is emerging to express bioactive foreign proteins because it has several advantages in that it is safe, economical, genetically stable and eukaryotic expression system comparing with other expression systems. However several limitations such as slow growth rate, low expression level and lack of well established down stream process need to be answered. As a preliminary approach to produce the immunologically interested molecules through the plant cell culture, we tested if granulocyte-macrophage colony stimulating factors (GM-CSFs) from both murine (mGM-CSF) and human (hGM-CSF) are produced as a biologically active form through plant cell culture. The murine and human GM-CSF genes were cloned into the plant expression vector, pBI121, and Ti-plasmid mediated transformation of tobacco leaves was conducted using Agrobacterium tumefaciens harboring both recombinant GM-CSF (rGM-CSF) genes. Cell suspension culture was established from the leaf-derived calli of transgenic tobacco plant. Northern blot analysis indicated the expression of the introduced mGM-CSF gene in both transgenic plant and cell suspension cultures. In addition, the biological activities of both murine and human GM-CSF from plant cell culture were confirmed by measuring the proliferation of the GM-CSF dependent FDC-PI and TF-1 cells, respectively.

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Neuron Circuit Using a Thyristor and Inter-neuron Connection with Synaptic Devices

  • Ranjan, Rajeev;Kwon, Min-Woo;Park, Jungjin;Kim, Hyungjin;Park, Byung-Gook
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제15권3호
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    • pp.365-373
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    • 2015
  • We propose a simple and compact thyristor-based neuron circuit. The thyristor exhibits bi-stable characteristics that can mimic the action potential of the biological neuron, when it is switched between its OFF-state and ON-state with the help of assist circuit. In addition, a method of inter-neuron connection with synaptic devices is proposed, using double current mirror circuit. The circuit utilizes both short-term and long-term plasticity of the synaptic devices by flowing current through them and transferring it to the post-synaptic neuron. The double current mirror circuit is capable of shielding the pre-synaptic neuron from the post synaptic-neuron while transferring the signal through it, maintaining the synaptic conductance unaffected by the change in the input voltage of the post-synaptic neuron.

저대역 센서 네트워크 기반의 양방향 보안등 관제 시스템 개발 (Development of a Bi-Directional Security Light Control System based on Low-Bandwidth Wireless Sensor Network)

  • 이호근;이상호;이석규;최정원
    • 조명전기설비학회논문지
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    • 제24권10호
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    • pp.58-66
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    • 2010
  • This paper shows an implementation and management result of wireless networks based security light control system, which performs a great role in protection of pedestrians and prevention of crime. Conventional security light units have severe limits in confirmation and inspection of security light unit failure, like wilful damage by someone or failure by influence of other equipment or failure by spontaneous heat-increase, and so on. In addition, local government offices are responsible for maintenance of security light units and as a matter of fact, most of civil complaints are about security light units. It is an obvious that the existing security light maintenance system reaches the limit and the security light maintenance problem is a difficulty of local government. Therefore, efficient security light control system is needed, which enables central control and intelligent maintenance. Moreover, the system has to be easy to control and has to be stable. In this study, wireless sensor network based security light control system is implemented, which is independent of programming language and platform, and which is simple to control and extend the system. The proven protocols, HTTP and SOAP, are utilized in order to improve the system reliability. This paper shows the excellence of our proposed system by implementing and operating it in real environment.

Structural ordering, electronic and magnetic properties of bundled $Mo_6S_9-_xI_x$ nanowires

  • Kang, Seoung-Hun;Tomanek, David;Kwon, Young-Kyun
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2009년도 제38회 동계학술대회 초록집
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    • pp.55-55
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    • 2010
  • We use ab initio density functional theory to determine the effect of bundling on the equilibrium structure, electronic and magnetic properties of $Mo_6S_{9-x}I_x$nanowires with x = 0, 3, 4.5, 6. Each unit cell of these systems contains two $Mo_6S_{6-x}I_x$ clusters connected by S3 linkages to form an ordered linear array. Due to the bi-stability of the sulfur linkages, the total energy of the nanowires exhibits typically many minima as a function of the wire length. We find that nanowires can switch over from metallic to semiconducting by applying axial stress. Structural order is expected in bundles with x=0 and x=6, since there is no disorder in the decoration of the Mo clusters. In bundles with other stoichiometries, we expect structural disorder to occur. We find the optimum inter-wire distance to depend sensitively on the orientation of the wires, but only weakly on x. It is also found that the electronic properties of nanowires are affected strongly due to bundling of nanowires exhibiting very unusual Fermi surfaces. Furthermore, ferromagnetic behaviors are observed in selected stable and many more unstable atomic arrangements in nanowire bundles.

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주조 방식 및 압연에 따른 연축전지용 납 합금 기판의 부식 특성 (Effects of Casting Method and Rolling on the Corrosion Behaviors of Pb Alloys for a Lead Acid Battery)

  • 오꽃님;이규혁;장희진
    • Corrosion Science and Technology
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    • 제20권5호
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    • pp.315-323
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    • 2021
  • In this study, we examined corrosion behaviors of two types of Pb alloys for a lead acid battery comparatively. One containing 6.6 wt% Sn, 36 mg/kg Bi, and 612.4 mg/kg Ca was prepared by twin-roll continuous casting. The other containing 5.2 wt% Sn, 30.5 mg/kg Ag, and 557 mg/kg Ca was made by twin-belt continuous casting. Potentiodynamic polarization tests were performed to evaluate corrosion resistance. Cyclic voltammetry was done to examine oxidation and reduction reactions occurring on the surface of each alloy in 4.8 M H2SO4 solution. Electrochemical test results implied that the Pb alloy prepared with the twin-belt casting method was less stable than that cast with the twin-roll method. Such results might be due to precipitations formed during the casting process. Rolling did not appear to affect the corrosion behavior of the twin-roll samples with Ag < 10 mg/kg, while it reduced the anodic reaction of Ag on the surface of the twin-belt sample with 30.5 mg/kg Ag.

Chemical and Mechanical Sustainability of Silver Tellurite Glass Containing Radioactive Iodine-129

  • Lee, Cheong Won;Kang, Jaehyuk;Kwon, Yong Kon;Um, Wooyong;Heo, Jong
    • 방사성폐기물학회지
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    • 제19권3호
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    • pp.323-330
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    • 2021
  • Silver tellurite glasses with melting temperature of approximately 700℃ were developed to immobilize 129I wastes. Long-term dissolution tests in 0.1 M acetic acid and disposability assessment were conducted to evaluate sustainability of the glasses. Leaching rate of Te, Bi and I from the glasses decreased for up to 16 d, then remained stable afterwards. On the contrary, tens to tens of thousands of times more of Ag was leached in comparison to the other elements; additionally, Ag leached continuously for all 128 d of the test owing to the exchange of Ag+ and H+ ions between the glasses and solution. The I leached much lower than those of other elements even though it leached ~10 times more in 0.1 M acetic acid than in deionized water. Some TeO4 units in the glass network were transformed to TeO3 by ion exchange and hydrolysis. These silver tellurite glasses met all waste acceptance criteria for disposal in Korea.

지하수위와 연계된 습지 식생의 비선형 동역학 (Non-linear dynamics of wetland vegetation induced by groundwater table)

  • 이옥정;김상단
    • 한국습지학회지
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    • 제21권2호
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    • pp.132-139
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    • 2019
  • 식생과 지하수위 사이의 양방향 상호 작용은 습지 식생의 동역학에 많은 영향을 미친다. 본 연구에서는 지하수위에 의해 영향을 받는 습지 식생의 비선형 동역학이 분석된다. 지하수위에 대한 영향은 습지 식생의 지배방정식에서 손실 항으로 설명되며, 지하수위 변화에 따라서 습지 식생이 어떻게 서로 다른 두 개의 안정적인 상태로 수렴될 가능성이 있게 되는지를 살펴보게 된다. 이러한 개념적 접근법으로부터 지하수위 변화에 따라 현재 습지에 존재하는 식생이 소멸되어 다른 식생 종으로 안정화되는 대변환에 대한 취약성이 분석된다.

Patch size adaptive image inpainting

  • Liu, Huaming;Lu, Guanming;Bi, Xuehui;Wang, Weilan
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제15권10호
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    • pp.3642-3667
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    • 2021
  • Texture synthesis technology has the advantages of repairing texture and structure at the same time. However, during the filling process, the size of the patch is fixed, and the content of the filling is not fully considered. In order to be able to adaptively change the patch size, we used the exemplar-based inpainting technique as the test algorithm, considering the image structure and texture, calculated the image structure patch size and texture patch size, and comprehensively determined the image patch size. This can adaptively change the patch size according to the filling content. In addition, we use multi-layer images to calculate the priority, so that the order of image repair was more stable. The proposed repair algorithm is compared with other image repair algorithms. The experimental results showed that the proposed adaptive image repair algorithm can better repair the texture and structure of the image, which proved the effectiveness of the proposed algorithm.