• Title/Summary/Keyword: Bi-Objective

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Anomaly detection of smart metering system for power management with battery storage system/electric vehicle

  • Sangkeum Lee;Sarvar Hussain Nengroo;Hojun Jin;Yoonmee Doh;Chungho Lee;Taewook Heo;Dongsoo Har
    • ETRI Journal
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    • v.45 no.4
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    • pp.650-665
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    • 2023
  • A novel smart metering technique capable of anomaly detection was proposed for real-time home power management system. Smart meter data generated in real-time were obtained from 900 households of single apartments. To detect outliers and missing values in smart meter data, a deep learning model, the autoencoder, consisting of a graph convolutional network and bidirectional long short-term memory network, was applied to the smart metering technique. Power management based on the smart metering technique was executed by multi-objective optimization in the presence of a battery storage system and an electric vehicle. The results of the power management employing the proposed smart metering technique indicate a reduction in electricity cost and amount of power supplied by the grid compared to the results of power management without anomaly detection.

Trends in Chinese Clinical Research on Herbal Medicine Treatment in Adolescent Polycystic Ovary Syndrome - Focusing on Randomized Controlled Clinical Trials - (청소년 다낭성 난소증후군 한약치료에 대한 중의학 임상연구 동향 -무작위 대조군 임상연구를 중심으로-)

  • Kim Hyo Eun;Jang Su Bi;Kim Ki Bong;Cheon Jin Hong
    • The Journal of Pediatrics of Korean Medicine
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    • v.38 no.2
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    • pp.53-67
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    • 2024
  • Objective This study aimed to assess the trend of randomized clinical trials conducted in China involving oral herbal medicine for treating adolescent polycystic ovary syndrome (PCOS). Methods We used the China National Knowledge Infrastructure as our primary resource and conducted a search using keywords such as "PCOS", "多囊卵巢" and "多囊卵巢综合征". We identified and analyzed seven RCTs. Results 1. The group receiving herbal medicine treatment demonstrated significant improvements in total efficiency, sex hormone levels, and ultrasound-measurable values compared to the control group. 2. Epimedii Herba (淫羊藿), Alviae Miltiorrhizae Radix (丹參), and Angelicae Gigantis et Acutilobae Radix (當歸) were among the most used herbs in Traditional Chinese medicine decoctions for treating PCOS. Conclusions The findings suggest that oral herbal medicine is an effective treatment for patients with PCOS. This study provides a foundation for future research on the use of oral herbal medicine in PCOS treatment.

Effect of flexure-extension coupling on the elastic instability of a composite laminate plate

  • H. Mataich;A. El Amrani;J. El Mekkaoui;B. El Amrani
    • Structural Engineering and Mechanics
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    • v.90 no.4
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    • pp.391-401
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    • 2024
  • The present study focuses on the effect of extension-bending coupling on the elastic stability (buckling) of laminated composite plates. These plates will be loaded under uni-axial or bi-axial in-plane mechanical loads, especially in the orthotropic or anti-symmetric cross-angle cases. The main objective is to find a limit where we can approximate the elastic stability behavior of angularly crossed anti-symmetric plates by the simple behavior of specially orthotropic plates. The contribution of my present study is to predict the explicit effect of extension-flexion coupling on the elastic stability of this type of panel. Critically, a parametric study is carried out, involving the search for the critical buckling load as a function of deformation mode, aspect ratio, plate anisotropy ratio and finally the study of the effect of lamination angle and number of layers on the contribution of extension-flexure coupling in terms of plate buckling stability. We use first-order shear deformation theory (FSDT) with a correction factor of 5/6. Simply supported conditions along the four boundaries are adopted where we can develop closed-form analytical solutions obtained by a Navier development.

Human lactoferrin efficiently targeted into caprine beta-lactoglobulin locus with transcription activator-like effector nucleases

  • Yuan, Yu-Guo;Song, Shao-Zheng;Zhu, Meng-Ming;He, Zheng-Yi;Lu, Rui;Zhang, Ting;Mi, Fei;Wang, Jin-Yu;Cheng, Yong
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.8
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    • pp.1175-1182
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    • 2017
  • Objective: To create genetically modified goat as a biopharming source of recombinant human lacotoferrin (hLF) with transcription activator-like effector nucleases. Methods: TALENs and targeting vector were transferred into cultured fibroblasts to insert hLF cDNA in the goat beta-lactoglobulin (BLG) locus with homology-directed repair. The gene targeted efficiency was checked using sequencing and TE7I assay. The bi-allelic gene targeted colonies were isolated and confirmed with polymerase chain reaction, and used as donor cells for somatic cell nuclear transfer (SCNT). Results: The targeted efficiency for BLG gene was approximately 10%. Among 12 Bi-allelic gene targeted colonies, five were used in first round SCNT and 4 recipients (23%) were confirmed pregnant at 30 d. In second round SCNT, 7 (53%), 4 (31%), and 3 (23%) recipients were confirmed to be pregnant by ultrasound on 30 d, 60 d, and 90 d. Conclusion: This finding signifies the combined use of TALENs and SCNT can generate biallelic knock-in fibroblasts that can be cloned in a fetus. Therefore, it might lay the foundation for transgenic hLF goat generation and possible use of their mammary gland as a bioreactor for large-scale production of recombinant hLF.

A Prospective Study on the Value of Ultrasound Microflow Assessment to Distinguish Malignant from Benign Solid Breast Masses: Association between Ultrasound Parameters and Histologic Microvessel Densities

  • Ah Young Park;Myoungae Kwon;Ok Hee Woo;Kyu Ran Cho;Eun Kyung Park;Sang Hoon Cha;Sung Eun Song;Ju-Han Lee;JaeHyung Cha;Gil Soo Son;Bo Kyoung Seo
    • Korean Journal of Radiology
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    • v.20 no.5
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    • pp.759-772
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    • 2019
  • Objective: To investigate the value of ultrasound (US) microflow assessment in distinguishing malignant from benign solid breast masses as well as the association between US parameters and histologic microvessel density (MVD). Materials and Methods: Ninety-eight breast masses (57 benign and 41 malignant) were examined using Superb Microvascular Imaging (SMI) and contrast-enhanced US (CEUS) before biopsy. Two radiologists evaluated the quantitative and qualitative vascular parameters on SMI (vascular index, morphology, distribution, and penetration) and CEUS (time-intensity curve analysis and enhancement characteristics). US parameters were compared between benign and malignant masses and the diagnostic performance was compared between SMI and CEUS. Subgroup analysis was performed according to lesion size. The effect of vascular parameters on downgrading Breast Imaging Reporting and Data System (BI-RADS) category 4A masses was evaluated. The association between histologic MVD and US parameters was analyzed. Results: Malignant masses were associated with a higher vascular index (15.1 ± 7.3 vs. 5.9 ± 5.6), complex vessel morphology (82.9% vs. 42.1%), central vascularity (95.1% vs. 59.6%), penetrating vessels (80.5% vs. 31.6%) on SMI (all, p < 0.001), as well as higher peak intensity (37.1 ± 25.7 vs. 17.0 ± 15.8, p < 0.001), slope (10.6 ± 11.2 vs. 3.9 ± 4.2, p = 0.001), area (1035.7 ± 726.9 vs. 458.2 ± 410.2, p < 0.001), hyperenhancement (95.1% vs. 70.2%, p = 0.005), centripetal enhancement (70.7% vs. 45.6%, p = 0.023), penetrating vessels (65.9% vs. 22.8%, p < 0.001), and perfusion defects (31.7% vs. 3.5%, p < 0.001) on CEUS (p ≤ 0.023). The areas under the receiver operating characteristic curve (AUCs) of SMI and CEUS were 0.853 and 0.841, respectively (p = 0.803). In 19 masses measuring < 10 mm, central vascularity on SMI was associated with malignancy (100% vs. 38.5%, p = 0.018). Considering all benign SMI parameters on the BI-RADS assessment, unnecessary biopsies could be avoided in 12 category 4A masses with improved AUCs (0.500 vs. 0.605, p < 0.001). US vascular parameters associated with malignancy showed higher MVD (p ≤ 0.016). MVD was higher in malignant masses than in benign masses, and malignant masses negative for estrogen receptor or positive for Ki67 had higher MVD (p < 0.05). Conclusion: US microflow assessment using SMI and CEUS is valuable in distinguishing malignant from benign solid breast masses, and US vascular parameters are associated with histologic MVD.

Carbohydrate, Lipid Inhibitory Activity and Antioxidant Activity of Extracts from Several Economic Resource Plants in Vitro

  • Boo, Hee-Ock;Shin, Jeoung-Hwa;Choung, Eui-Su;Bang, Mi-Ae;Choi, Kyung-Min;Song, Won-Seob
    • Korean Journal of Plant Resources
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    • v.26 no.3
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    • pp.374-382
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    • 2013
  • The objective of this study was determined to evaluate ${\alpha}$-amylase, ${\alpha}$-glucosidase, pancreatic lipase inhibition in vitro and DPPH radical scavenging activity of the several Korean resources plants. The ${\alpha}$-amylase inhibitory activity of Salicornia herbacea, Erythronium japonicum (flower) and Phragmites communis (root) in water extract showed relatively high 62.8%, 66.5% and 69.3%, respectively. The ${\alpha}$-amylase inhibitory activity of Citrus junos (pericarp) and Cornus officinalis in methanol extract was found to have an effect with 32.8% in Citrus junos (pericarp) and 60.9% in Cornus officinalis. Corylopsis coreana in both water and methanol extract had the highest ${\alpha}$-glucosidase inhibitory activity of 81.7% and 89.5%, while the extract of Portulaca oleracea, Ficus carica and Citrus junos was not measured ${\alpha}$-glucosidase inhibitory activity at given experiment concentration. Depending on the extraction solvent and the plant species, it was observed that there was a significant difference in ${\alpha}$-glucosidase inhibitory activity. The pancreatic lipase inhibitory activity showed relatively higher in the methanol extract than water extract except pericarp of Citrus junos. The DPPH radical scavenging activity of selected plants was much difference between measured plant species, and showed that the increase was proportional to the concentration. These results suggested that selected plants had the potent biological activity on carbohydrate, lipid Inhibitory activity and antioxidant activity, therefore these plant resources could be a good materials to develop medicinal preparations, nutraceuticals or health functional foods for diabetes or obesity.

A Study on the Selection of Environmental Impact Assessment Factors through Public Participation (주민참여를 통한 환경영향평가 항목선정에 관한 연구 : 원자력발전소 개발사업을 대상으로)

  • Kim, Kwi-Gon;Youn, So-Won;Sung, Hyun-Chan;Park, Byoung-Won
    • Journal of Environmental Impact Assessment
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    • v.4 no.1
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    • pp.25-35
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    • 1995
  • The objective of the study is to produce preferential impact assessment factors for Environmental Impact Assessment by considering regional features and public participation in the initial stages of EIA. In order to produce preferential impact assessment factors, the study was carried out through theoretical research and a survey of public awareness as a ways to reflect public participation based on theoretical research. The survey of public awareness was conducted in the form of an interview to review the impact which the construction of atomic power plants at Hyo-am village, Jang-an, Kyungsang Province and Bi-hak village, Suhsang-myon, Ulsan-Kun will have on the surrounding environment: to reflect public participation on deciding preferential assessment: and to determine the extent of alternatives of the proposed project. As the result of the study, the following were identified as preferential assessment factors in the settlement and surrounding areas cultivation marine products, change of temperature of seawater due to flow of warm water, land use(negative), noise vibration during construction, existing plants, erosion accumulation, influx of manpower for construction(negative), recreation landscaping during construction and operation, change in flow of transportation during construction, the quality of seawater during construction and operation were produced as preferential assessment factors in both settlement area and neighboring areas. In the settlement area, the educational environment(negative & positive) and positive aspects of the influx of manpower for construction were also identified as preferential assessment factors.

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A Study on the Selection of Environmental Impact Assessment Factors through Public Participation (주민참여를 통한 환경영향평가 항목선정)

  • Kim, Kwi-Gon;Youn, So-Won;Sung, Hyun-Chan;Park, Byoung-Won
    • Journal of Environmental Impact Assessment
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    • v.4 no.3
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    • pp.15-26
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    • 1995
  • The objective of the study is to produce preferential impact assessment factors for Environmental Impact Assessment by considering regional features and public participation in the initial stages of EIA. In order to produce preferential impact assessment factor, the study was carried out through theoretical research and a survey of public awareness as way to reflect public participation based on theoretical research. The survey of public awareness was conducted in the form of an interview to review the impact which the construction of atomic power plants at Hyo-am village, Jang-an, Kyungsang Province and Bi-hak village, Suhsang-myon, Ulsan-Kun will have on the surrounding environment : to reflect public participation on deciding preferential assessment: and to determine the extent of alternatives of the proposed project. As the result of the study, the followings were identified as preferential assessment factors in the displacing settlement and surrounding areas: cultivation marine products, change of temperature of seawater due to flow of warm water, land use (negative), noise vibration during construction, existing vegetations, erosion sedimentation, influx of manpower for construction(negative), recreation landscaping during construction and operation, change in flow of transportation during construction, the quality of seawater during construction and operation were produced as preferential assessment factors in both displacing area and neighboring areas. In the displacing settlement area, the educational environment(negative & positive) and positive aspects of the influx of manpower for construction were also identified as preferential assessment factors.

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Study on Service Identity and Identity Framework

  • Kang, Hwa-Sun;Pan, Young-Hwan
    • Journal of the Ergonomics Society of Korea
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    • v.31 no.1
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    • pp.33-40
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    • 2012
  • Objective: Service industry has become the most important industry among various economic activities, as the percentage of service related industry in advanced nations is over 60% of their GDP and the percentage of service industry in South Korea, a traditional manufacturing nation, now takes up over 60% of the entire economy. Background: Such industry paradigm shift has changed consumers from those that simply purchased products into groups of people that evaluate the companies that manufacture products, thereby further intensifying competition among companies and increasing the importance of integrated communication between companies and consumers. However, the excessive existence of sub-identities that have been developed for integrated management of the existing corporate identities, as well as the undifferentiated general management strategies by companies are creating confusion not only for consumers but also for various corporate interest parties. In addition, service identity strategy has become the most important strategy than any other sub-identity strategies in forming corporate identity at the increased importance of corporate service in the era of service industry. However, the current domestic circumstance is that the concept of service identity has not been well established through specific related studies. Method: Accordingly, the existing academic and field studies on the corporate identity(CI), brand identity(BI) and product identity(PI) used for the communication with consumers were reviewed in this study to establish and summarize the concept of service identity(SI) that appeared at the service economization. Results: The purpose is to examine the kind of change that could be brought about by SI for the corporate integrated identity strategy developed through the existing corporate, brand & product image in order to present a new direct in corporate identity strategy according to the industry paradigm shift through a SI centered new corporate identity framework. Conclusion: For preparing the new era of service industry, the corporate integrated identity strategy must be integrate with concept of service identity and which is essential to differential from other companies. Application: The proposed concept and framework of service identity on this paper will help to understand and clearly define why service identity is important factor of the new idea of corporate identities.

Accident Rate Forecasting Model by Using Speed on Freeway (속도를 이용한 고속도로 구간 사고율 예측 모형)

  • Jeong, Eun-Bi;O, Cheol
    • Journal of Korean Society of Transportation
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    • v.29 no.4
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    • pp.103-111
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    • 2011
  • The speed is one of the significant factors affecting accident occurrence. In particular, freeway accidents are highly associated with the speed because vehicles travel on the freeway at higher speed leading to greater potential of severer injury. Efforts attempting to relating speed with accident occurrence have not been significantly made in Korea. The objective of this study is to model the relationship between speed and accident rate on freeways. Loop detector data and accident data obtained from a stretch of Kyungboo freeway during the recent five years, 2005-2009, were used to establish the model. Multiple linear regression analyses showed that median, minimum and standard deviation of speed were contributing variables in the model. The statistical significance identified by the analyses supports the feasibility of the model in evaluating various transportation policies and operations strategies in terms of traffic safety.