• Title/Summary/Keyword: Benefit criteria

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Postoperative chemoradiotherapy versus radiotherapy alone for elderly cervical cancer patients with positive margins, lymph nodes, or parametrial invasion

  • Cushman, Taylor R.;Haque, Waqar;Menon, Hari;Rusthoven, Chad G.;Butler, E. Brian;Teh, Bin S.;Verma, Vivek
    • Journal of Gynecologic Oncology
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    • v.29 no.6
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    • pp.97.1-97.12
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    • 2018
  • Objective: Women with cervical cancer (CC) found to have positive surgical margins, positive lymph nodes, and/or parametrial invasion receive a survival benefit from postoperative chemoradiotherapy (CRT) vs. radiation therapy (RT) alone. However, older women may not benefit to the same extent, as they are at increased risk of death from non-oncologic causes as well as toxicities from oncologic treatments. This study sought to evaluate whether there was a survival benefit of CRT over RT in elderly patients with cervical cancer. Methods: The National Cancer Database was queried for patients ${\geq}70$ years old with newly diagnosed IA2, IB, or IIA CC and positive margins, parametrial invasion, and/or positive nodes on surgical resection. Statistics included logistic regression, Kaplan-Meier overall survival (OS), and Cox proportional hazards modeling analyses. Results: Altogether, 166 patients met inclusion criteria; 62 (37%) underwent postoperative RT and 104 (63%) underwent postoperative CRT. Younger patients and those living in areas of higher income were less likely to receive CRT, while parametrial invasion and nodal involvement were associated with an increased likelihood (p<0.05 for all). There were no OS differences by treatment type. Subgroup analysis by number of risk factors, as well as each of the 3 risk factors separately, also did not reveal any OS differences between cohorts. Conclusion: In the largest such study to date, older women with postoperative risk factor(s) receiving RT alone experienced similar survival as those undergoing CRT. Although causation is not implied, careful patient selection is paramount to balance treatment-related toxicity risks with theoretical outcome benefits.

Attitude of the Korean dentists towards radiation safety and selection criteria

  • Lee, Byung-Do;Ludlow, John B.
    • Imaging Science in Dentistry
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    • v.43 no.3
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    • pp.179-184
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    • 2013
  • Purpose: X-ray exposure should be clinically justified and each exposure should be expected to give patients benefits. Since dental radiographic examination is one of the most frequent radiological procedures, radiation hazard becomes an important public health concern. The purpose of this study was to investigate the attitude of Korean dentists about radiation safety and use of criteria for selecting the frequency and type of radiographic examinations. Materials and Methods: The study included 267 Korean dentists. Five questions related to radiation safety were asked of each of them. These questions were about factors associated with radiation protection of patients and operators including the use of radiographic selection criteria for intraoral radiographic procedures. Results: The frequency of prescription of routine radiographic examination (an example is a panoramic radiograph for screening process for occult disease) was 34.1%, while that of selective radiography was 64.0%. Dentists' discussion of radiation risk and benefit with patients was infrequent. More than half of the operators held the image receptor by themselves during intraoral radiographic examinations. Lead apron/thyroid collars for patient protection were used by fewer than 22% of dental offices. Rectangular collimation was utilized by fewer than 15% of dental offices. Conclusion: The majority of Korean dentists in the study did not practice radiation protection procedures which would be required to minimize exposure to unnecessary radiation for patients and dental professionals. Mandatory continuing professional education in radiation safety and development of Korean radiographic selection criteria is recommended.

Development of the Evaluation Criteria for the Usefulness of Biological Resources (생물자원의 유용성 평가 기준 개발)

  • Lee, Hyun-Woo;Kim, Dong-Wook;Won, Hyo-Sig
    • Journal of Environmental Policy
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    • v.12 no.4
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    • pp.3-21
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    • 2013
  • This research aims to analyze the usefulness of biological resources from the perspective of the users from various angles and after taking these factors into consideration, provide policy implication and scientific criteria for judging and choosing useful biological resources. Among biological resources defined in CBD, the subject of the research was confined to the biological resource as a unit which can be actually used in benefit sharing and trade. Also, among diverse values of biological resources, the usefulness was assessed focusing on the utility value and scarcity. Usefulness was rated on a scale of 1 to 5 (5 grades). The rating was adjusted for the biological resources that need to be managed as a part of the management policy. It is expected that the criteria of this study will be useful for the following: (1) the procurement of biological resources in the need for primary protection and management (2) the utilization of secured biological resources by analyzing their utility value and using them in biological resources industry (3) securement of sovereignty over biological resources, such as prior access permit under the Nagoya protocol, through management and protection of biological resources in Korea.

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Therapeutic Duplication Criteria Development of Respiratory System Drugs (호흡기계 작용 약물의 치료군 중복처방 평가기준 개발)

  • Choi, Kyung-Eob;Sohn, Hyun-Soon;Kim, Nam-Hyo;Shin, Hyun-Taek;Lee, Young-Sook
    • YAKHAK HOEJI
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    • v.56 no.2
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    • pp.126-135
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    • 2012
  • Purpose: To develop therapeutic duplication criteria for the drugs used for respiratory diseases. Method: Therapeutic duplication was defined as "more than 2 drug ingredient-usage in which each has the same therapeutic effect and combination therapy does not confer additional therapeutic benefit". Respiratory system drugs approved in Korea were examined for the study. The WHO's Anatomical Therapeutic Chemical Classification System was used for grouping of the corresponding drug ingredients. The principles and recommendations on combination usage or multiple drug regimens were reviewed by using the clinical practice guidelines, textbooks, product labelings, and clinical articles. Clinical expert group consultation was performed and expert opinions were incorporated into the final criteria. Results: Nine hundred sixty two drug products with Korean Food and Drug Administration classification codes of 141, 149, 222, and 229 were evaluated, of which 87 active ingredients were composed. The drug ingredients were classified into 12 groups (antihistamines, oral nasal decongestants, leukotriene receptor antagonists, inhaled anticholinergics, inhaled corticosteroids, oral ${\beta}2$-agonists, long-acting ${\beta}2$-agonists, short-acting ${\beta}2$-agonists, xanthines, antiallergics, mucolytics and cough suppressants). The use of more than 2 drug ingredients including the same group was therapeutic duplication, and thus combination should be recommended not to be used. Conclusion: Twelve drug groups were identified as therapeutic duplication criteria. Combination therapy within each group should not be used otherwise therapeutic benefits outweigh potential risks.

Computational design of mould sprue for injection moulding thermoplastics

  • Lakkannan, Muralidhar;Mohan Kumar, G.C.;Kadoli, Ravikiran
    • Journal of Computational Design and Engineering
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    • v.3 no.1
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    • pp.37-52
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    • 2016
  • To injection mould polymers, designing mould is a key task involving several critical decisions with direct implications to yield quality, productivity and frugality. One prominent decision among them is specifying sprue-bush conduit expansion as it significantly influences overall injection moulding; abstruseness anguish in its design criteria deceives direct determination. Intuitively designers decide it wisely and then exasperate by optimising or manipulating processing parameters. To overwhelm that anomaly this research aims at proposing an ideal design criteria holistically for all polymeric materials also tend as a functional assessment metric towards perfection i.e., criteria to specify sprue conduit size before mould development. Accordingly, a priori analytical criterion was deduced quantitatively as expansion ratio from ubiquitous empirical relationships specifically a.k.a an exclusive expansion angle imperatively configured for injectant properties. Its computational intelligence advantage was leveraged to augment functionality of perfectly injecting into an impression gap, while synchronising both injector capacity and desired moulding features. For comprehensiveness, it was continuously sensitised over infinite scale as an explicit factor dependent on in-situ spatio-temporal injectant state perplexity with discrete slope and altitude for each polymeric character. In which congregant ranges of apparent viscosity and shear thinning index were conceived to characteristically assort most thermoplastics. Thereon results accorded aggressive conduit expansion widening for viscous incrust, while a very aggressive narrowing for shear thinning encrust; among them apparent viscosity had relative dominance. This important rationale would certainly form a priori design basis as well diagnose filling issues causing several defects. Like this the proposed generic design criteria, being simple would immensely benefit mould designers besides serve as an inexpensive preventive cliché to moulders. Its adaption ease to practice manifests a hope of injection moulding extremely alluring polymers. Therefore, we concluded that appreciating injectant's polymeric character to design exclusive sprue bush offers a definite a priori advantage.

Evaluation Criteria for Suitable Authentication Method for IoT Service Provider in Industry 4.0 Environment (4차 산업혁명 시대의 IoT 서비스 참여 주체에 대한 적합한 인증수단 선택을 위한 평가기준)

  • Jeong, Kwang Seob;Bae, Sukjoo;Kim, Hyoungtae
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.40 no.3
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    • pp.116-122
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    • 2017
  • Advances in information technology, communication and network technology are radically facilitating digital convergences as the integration of human, equipment, and space in the current industry 4.0 era. In industry 4.0 environment, the vast amount of information with networked computing technology can be simultaneously accessible even in limited physical space. Two main benefit points out of these information are the convenience and efficiency in their online transactions either buying things online or selling online. Even though there exist so many benefits that information technology can create for the people doing business over the internet there is a critical problem to be answered. In spite of many such advantages, however, online transactions have many dysfunctions such as personal information leakage, account hacking, and cybercrime. Without preparing the appropriate protection methods or schema people reluctantly use the transaction or would find some other partners with enhanced information security environment. In this paper we suggested a novel selection criteria that can be used to evaluate the reliable means of authentication against the expected risks under on-going IoT based environment. Our selection criteria consists of 4 steps. The first step is services and risk identification step. The second step is evaluation of risk occurrence step. The third step includes the evaluation of the extent of damage. And the final step is the assessment of the level of risk. With the help of the above 4 step-approach people can systematically identify potential risks hiding in the online transactions and effectively avoid by taking appropriate counter actions.

Improvement of Housing Market Related Laws and Policies Causing Sudden Changes according to the Application Criteria (적용기준에 따라 큰 변화를 수반하는 주택시장관련 법률 및 정책의 개선방안)

  • Lee, Yong-Seong;Kim, Kyung-Hwan
    • Korean Journal of Construction Engineering and Management
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    • v.20 no.5
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    • pp.12-20
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    • 2019
  • This study analyzes and suggests improvement direction for the problems of housing related market laws and policies that cause sudden changes according to the application criteria. These laws and policies include income deduction from housing subscription, monthly rent loan for housing stability, high price house, penalty points from poor quality construction, and real estate brokerage commission. Each has one or more specific values that decide application criteria causing noticeable different results. Benefit or loss can be decided when an application range is changed by a small difference of the application value near to the boundary. This study suggest to use equations instead of a certain values to remove those sudden changes and to make them steadily increasing slopes which can be lines or curves. The concept can be applied to other laws and policies that have significantly different results between criteria.

Analysis of Socio-economic Effects of Land Consolidation and On-farm Development Project (경지정리사업(耕地整理事業)의 사회경제적효과분석(社會經濟的效果分析))

  • Lim, Jae Hwan;Kim, Jae Hong;Yeo, Soon Duck
    • Korean Journal of Agricultural Science
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    • v.27 no.2
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    • pp.158-175
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    • 2000
  • Up to date, the economic feasibility analysis on land consolidation and on-farm development projects were mainly depended upon the direct benefits from market value of project outputs. Therefore the projects were neglected in allocation of the government's financial funds and loans on account of undervaluation of the project benefits including socio-economic and environmental values of the projects. Accordingly the Extended Benefit Cost Analysis Method should be adapted to cover not only the benefits such as non-market values of environmental functions of the projects and but also the economic market values of the project outputs. The main objectives of this study is (1) to provision of the guideline for economic feasibility analysis based on the IBRD and ADB guidelines, (2) to estimate the benefits such as Productivity increase effect, labor saving effect, off-farm income increase effect during off-farm season, saving of O&M cost of farm mechanization, enhance of farmer's public health, increase of environmental public function of paddy fields, effect of food security and establishment of peaceful and uncontroversial rural society by implementing the land consolidation and on-farm development, (3) to introduce the newly adapted analytical method as the extended benefit cost analysis which could make possible the analysis of non-market goods such as the food security value and the environmental public value of paddy fields. To carry out the study, the publication on the guideline for economic analysis of agricultural projects were reviewed and consulted and for the post evaluation of the land consolidation and on-farm development project, field survey in Jeongja area were made for the feasibility study of the project by new method. According to the initial project plan, Jeongja land consolidation and on-farm development project has 96ha of benefit area and the project was started in 1989 and completed in the spring, 1990. The total project costs were amounted to 1,052 million won and the annual project benefits were estimated at 135.4 million in 1989 constant market prices. On the other hand, the newly estimated project benefits as a part of post evaluation of the project were amounted to 602.1 million won including all the benefits from the market and non-market commodities of the project as mentioned above column. The original IRP(Internal rate of return) of the project was estimated at 15.81%. On the other hand, the IRR of the post evaluation of the project was amounted to 16.83%. In case of including the benefit from the environment public function of paddy field, the SRR(Social Rate of Return) was reached to 38.81% and when we added the benefit from food security of the project, the SRR showed very high rate as 46.41%. In conclusion, the project were verified socio-economically feasible and environmentally sustainable considering the above decision making criteria.

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A Study on the Decision Method for CM Organization of Skyscraper Projects in Korea using the Pugh-Matrix (의사결정 매트릭스를 활용한 국내 초고층 프로젝트의 CM 조직 구성 결정방법에 관한 연구)

  • Lim, Jae-Bok;Choi, Won-Cheol;Kim, Jae-Jun
    • Journal of The Korean Digital Architecture Interior Association
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    • v.10 no.2
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    • pp.39-47
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    • 2010
  • In this study, there should be a debation on the methods, such as considerations on the CM organization of skyscraper project for the client's side, process and impact factors need to be taken, and suggesting the evaluation and selection criteria, which may lead strategic decision-making by the client. Owner of the CM organizational decision to establish a variety of alternatives, the range of CM performance characteristics of the project, considering the weight and also by evaluating the effectiveness of appropriate alternative is selected. Domestic skyscraper project, decisions about the CM organization for 'S Tower' prior to the proposed decision and the criteria was applied. As a result, domestic CM/PM companies and overseas CM/PM companies were doing business as J/V, Supervision of the integration work order types showed the highest performance levels. when they ordered CM services. The project cost reduced and organizational improvements, the results of applying alternative way, improve on-site construction plans, sharing key technologies, process improvement plan could benefit from such expectations.

A Study of College students's Consumer Behavior of the Midwest(Yunnam) in China(Part II): The Consumer's Traits of Market Segmentation Based on the Apparel Benefits (중국 중서부 지역(운남성) 대학생들의 소비자 행동연구(제 2보): 의복추구혜택에 따른 세분시장의 소비자특성)

  • Lee, Okhee
    • Journal of Fashion Business
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    • v.18 no.4
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    • pp.97-113
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    • 2014
  • This study investigates consumer's traits of market segmentation based on the apparel benefits. The subjects were 302 college students living in Yunnam, China. The mean, ANOVA, factor analysis, Duncan test, and K-means cluster analysis were used for statisticals analysis. The results of this study are as follows. The college students were classified, into six subdivisions, according to the apparel benefits by cluster analysis: indifference group, utility pursuit group, hedonic/brand pursuit group, individuality pursuit group, social recognition/fashion pursuit group, and pursuit benefits-minded group. In the factors of happiness-pursuing and life-centered of materialism, significant differences were found according to the groups of apparel benefits, and all factors of symbolic consumption and brand loyalty were found to have significant differences according to the groups of apparel benefits. The evaluation criteria of clothing were significantly different, depending on apparel benefits subdivision in criteria of aesthetic, socio-psychological, and utility. The use of information was shown to have significant differences, according to the groups of apparel benefits. The study results are highly expected to be utilized as useful sources in marketing plans for the midwest of China.