• Women's Health Nursing
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• v.9 no.2
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• pp.161-169
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• 2003

The purpose of this study was to identify menstrual symptoms, coping and Relief of Symptoms used by female college students. A convenience sample of 202 students were obtained from two colleges in Seoul. Data were collected through questionnaires from September 10 to December 18, 2001, Three instruments were used in this study, the Menstrual Symptoms Questionnaire by Park K. R(1988) and Menstrual Coping Questionnaire and Relief of Symptoms by Billings & Moos(1981) modified for this study. 1)Part time instructor, Department of Nursing, Pochon CHA University The data were analyzed by descriptive statistics, t-test, ANOVA with the SPSS 10.0 program. The result of this study are as follows. 1. Prevalence rate of dysmenorrhea was 91.6%. 2. The total mean score for menstrual symptoms was 1.89 of a possible total of 5 and mean score for each category was, 2.26 for water retention, 2.11 for negative affect, 2.02 for pain, 1.83 behavioral change, 1.69 for autonomic reactions, and 1.53 for concentration. 3. According to the result of this study, statistical differences were found for age (F=3.76, p=0.01), menstrual fear (t=2.02, p=0.04), dysmenorrhea (t=7.73, p=0.02), and taking medication (t=5.95, p=0.00). 4. The coping mode with the highest scores were 'rest and go to bed (83.7%)', 'regard mensturation as a physiological and temporary phenomenon (68.3%)', 'take a warm shower(66.8%)'. The most frequently used methods to relief of symptoms were 'take pain killers (99.9%)', 'to apply hot water bag on painful parts of the body (96.6%)' and 'rest and go to bed (88.8%)'.

• Journal of Preventive Medicine and Public Health
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• v.43 no.6
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• pp.513-522
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• 2010

Objectives: The purpose of this study was to define the association between the medical utilization of osteoarthritis patient and its related factors. Methods: We used the 2005 Korean National Health and Nutrition Survey data and we enrolled 2833 participants who were forty or older and who were diagnosed as having osteoarthritis by a doctor within 1 year and who had suffered from osteoarthritis for more than 3 months. The Andersen behavioral model was used as the analytic framework, and the variables were categorized into predisposing, enabling, and need factors. To determine the influence of each variable on the medical utilization of osteoarthritis patient, we applied hierarchical logistic regression analysis with two stages: the first stage included the predisposing and enabling factors and the second stage included the need factors. Results: On the hierarchical logistic analysis, the variables of personal income, the type of medical security, the duration of arthritis related symptoms within 1 month, the subjective health status and the duration of osteoarthritis showed a statistically significant association with medical utilization in men. And the variables of age, limitation activity due to osteoarthritis, arthritis related symptoms within 1 month, and the subjective health status had a statistically significant association with medical utilization in women. Conclusions: The patients who tend to receive less care are those who suffer less from symptoms of osteoarthritis, those who are within the initial phase, or those with a low-level severity of osteoarthritis. It is necessary to encourage patients to receive the treatment in the initial phase.

• The Korean Journal of Physiology and Pharmacology
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• v.22 no.2
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• pp.183-192
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• 2018

Post-traumatic stress disorder (PTSD) is a trauma-induced psychiatric disorder characterized by impaired fear extermination, hyperarousal, anxiety, depression, and amnesic symptoms that may involve the release of monoamines in the fear circuit. The present study measured several anxiety-related behavioral responses to examine the effects of berberine (BER) on symptoms of anxiety in rats after single prolonged stress (SPS) exposure, and to determine if BER reversed the dopamine (DA) dysfunction. Rats received BER (10, 20, or 30 mg/kg, intraperitoneally, once daily) for 14 days after SPS exposure. BER administration significantly increased the time spent in the open arms and reduced grooming behavior during the elevated plus maze test, and increased the time spent in the central zone and the number of central zone crossings in the open field test. BER restored neurochemical abnormalities and the SPS-induced decrease in DA tissue levels in the hippocampus and striatum. The increased DA concentration during BER treatment may partly be attributed to mRNA expression of tyrosine hydroxylase and the DA transporter in the hippocampus, while BER exerted no significant effects on vesicular monoamine transporter mRNA expression in the hippocampus of rats with PTSD. These results suggest that BER had anxiolytic-like effects on behavioral and biochemical measures associated with anxiety. These findings support a role for reduced anxiety altered DAergic transmission and reduced anxiety in rats with PTSD. Thus, BER may be a useful agent to treat or alleviate psychiatric disorders like those observed in patients with PTSD.

• Korean Journal of Biological Psychiatry
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• v.16 no.1
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• pp.15-24
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• 2009

Objectives : The purpose of this study is to examine the efficacy and side effects of quetiapine and haloperidol for the treatment of symptoms of delirium. Methods : One hundred and seven patients with delirium were recruited and randomly assigned to receive a flexible-dose regimen of quetiapine or haloperidol over 7days and seventy-seven patients completed the study(quetiapine group N=40, haloperidol group N=37). The severity of delirium was assessed by using Memorial Delirium Assessment Scale(MDAS) scores, the psychiatric and behavioral symptoms were assessed by Neurobehavioral Rating Scale(NRS) scores, and the cognitive status was measured by Mini-mental state examination Korean version(MMSE-K) scores. The side effects were measured by Drug Induced Extrapyramidal Symptoms Scale(DIEPSS) scores. Results : MDAS scores significantly improved in both treatment groups. NRS scores also significantly improved in both treatment group, but the group-by-time effect approached significance, likely caused by the greater decrease in scores of the quetiapine group. MMSE-K scores significantly improved only in the quetiapine group. Side effects associated with treatment were not significant in either treatment groups. Conclusion : This study suggests that quetiapine is as efficacious as haloperidol in the treatment of delirium. In particular, quetiapine seems to improve psychiatric and behavioral problems of delirium and was more effective than haloperidol in cognitive improvement.

• Journal of Korean Academy of Nursing
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• v.46 no.4
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• pp.475-489
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• 2016

Purpose: This study was a systematic review and meta-analysis designed to investigate the effects of stimulation-oriented interventions for behavioral problems among people with dementia. Methods: Based on the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA), a literature search was conducted using seven electronic databases, gray literature, and other sources. Methodological quality was assessed using the Scottish Intercollegiate Guidelines Network (SIGN) for randomized controlled trials (RCTs). Data were analyzed using R with the 'meta' package and the Comprehensive Meta-Analysis (CMA 2.0) program. Results: Sixteen studies were included for meta-analysis to investigate the effect of stimulation-oriented interventions. The quality of individual studies was rated as '++' for eight studies and '+' for the rest. The effect sizes were analyzed according to three subgroups of interventions (light, music, and others); Hedges' g=0.04 (95% CI: -0.38~0.46), -0.23 (95% CI: -0.56~0.10), -0.34 (95% CI: -0.34~0.00), respectively. To explore the possible causes of heterogeneity ($I^2=62.8%$), meta-regression was conducted with covariates of sample size, number of sessions, and length of session (time). No moderating effects were found for sample size or number of sessions, but session time showed a significant effect (Z=1.96, 95% CI: 0.00~0.01). Finally, a funnel plot along with Egger's regression test was performed to check for publication bias, but no significant bias was detected. Conclusion: Based on these findings, stimulation-oriented interventions seem to have a small effect for behavioral problems among people with dementia. Further research is needed to identify optimum time of the interventions for behavioral problems among dementia pateints.

• Biomolecules & Therapeutics
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• v.22 no.5
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• pp.453-459
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• 2014

Chronic mild stress (CMS) has been reported to induce an anhedonic-like state in mice that resembles some of the symptoms of human depression. In the present study, we used a chronic mild stress animal model of depression and anxiety to examine the responses of two strains of mice that have different behavioral responsiveness. An outbred ICR and an inbred C57BL/6 strain of mice were selected because they are widely used strains in behavioral tests. The results showed that the inbred C57BL/6 and outbred ICR mice were similarly responsive to CMS treatment in sucrose intake test (SIT) and open field test (OFT). However, the two strains showed quite different responses in forced swimming test (FST) and novelty-suppressed feeding (NSF) test after 3 weeks of CMS treatment. Only C57BL/6 mice displayed the depression- and anxiety-like behavioral effects in response to CMS treatment in FST and NSF test. Our results suggest that there are differences in responsiveness to CMS according to the different types of strain of mice and behavioral tests. Therefore, these results provide useful information for the selection of appropriate behavioral methods to test depression- and anxiety-like behaviors using CMS in ICR and C57BL/6 mice.

• Korean Journal of Biological Psychiatry
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• v.26 no.2
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• pp.79-87
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• 2019

Objectives The aim of this study was to investigate the impact of clinical and psychological factors on the quality of life of children and adolescents with epilepsy and their families. Methods Children and adolescents with epilepsy and their families (n = 63, age range = 6-17 years) completed questionnaires on epilepsy-related variables, quality of life, children's depressive symptoms, children's anxiety, children's behavioral problems, children's attention problems, parental stress, and parental anxiety. Stepwise regression analysis was performed to determine the significant predictive variables that affect quality of life. Results In the correlational analysis, children's attention problems (r = 0.363, p = 0.004), parental anxiety (r = 0.377, p = 0.003), parental stress (r = 0.564, p < 0.001), and children's behavioral problems (r = 0.503, p < 0.001) showed a significant correlation with quality of life. Parental stress (β = 0.415, p = 0.001, adjusted R² = 0.345) and children's behavioral problems (β = 0.285, p = 0.02, adjusted R² = 0.345) were significantly related to the quality of life. Conclusions Clinicians should pay attention to parental stress and children's behavioral problems, which affect quality of life in families with pediatric epilepsy.

• Journal of Korean Neuropsychiatric Association
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• v.56 no.2
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• pp.89-97
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• 2017

Objectives The Behavioral Activation of Depression Scale (BADS) has been reported to be a valid tool for assessing the different behavioral aspects of depression, such as activation, rumination or avoidance, and functional impairment. The aim of this study was to assess the reliability and validity of the Korean version of BADS (K-BADS). Methods A sample of 196 outpatients completed the K-BADS and the data were analyzed for internal consistency and factor structures. An additional 51 outpatients re-filled the K-BADS after two weeks for the test-retest reliability. To test for the validity, the Hospital Anxiety and Depression Scale (HADS), Working Alliance Inventory (WAI), Drug Attitude Inventory-10 (DAI-10), and Mindfulness Attention Awareness Scale (MAAS) were administered. Results Internal consistency of K-BADS was good (Cronbach's alpha=0.843) and principal component factor analysis revealed the four-factor structure. The K-BADS showed a reasonable test-retest reliability (r=0.863, p<0.001). The total score of K-BADS correlated significantly with the total scores of the HADS depression (r=-0.694) and HADS anxiety (r=-0.681). No correlations were found between the K-BADS and the K-WAI (r=0.170) and between the K-BADS and the K-DAI-10 (r=0.311). Conclusion The K-BADS is a reliable and valid instrument for measuring the behavioral activation for depression in Korean patients with depressive symptoms.

• Journal of Family Relations
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• v.21 no.3
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• pp.49-72
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• 2016

Objectives: The purpose of this study is to develop a cognitive behavioral therapy program for ego-integrity of depressed elderly women living alone, and to verify its effectiveness. Method: The subjects of this study were composed of elderly women(age 65 and older) living alone who had basic literacy skills, 24 or higher in mental state examination(MMSE-K), and 6 or higher in elderly depression(GDS). 29 women were randomly assigned into an experimental group(cognitive behavioral therapy), a comparison group(reminiscence therapy) and a control group. The experimental group and the comparison group retrospectively participated in a 90-minute therapy session twice a week for a total of 12 weeks. The effectiveness of the program was assessed through a pretest, posttest, and 2-month follow-up test. The data collected were analyzed with SPSS 22.0 statistical program. Results: The main findings of this study are as follows. First, at posttest ego-integrity and self-esteem marked higher scores in both of the experimental group and the comparison group than in the control group, but the experimental group marked comparatively higher scores than the comparison group. For dysfunctional attitude, only the experimental group showed lower scores compared to the comparison group and the control group. Second, at posttest depression marked lower scores in the experimental group compared to the comparison group and the control group. Third, at posttest problem-solving and support-seeking coping strategies marked higher scores in the experimental group compared to the comparison group and the control group. Fourth, the significant improvements remained at 2-month follow-up test. Conclusions: Cognitive behavioral therapy resulted in improvements of the ego-integrity and related symptoms of depressed elderly women living alone at posttest and 2-month follow-up test respectively.

• Journal of the Korean Society of School Health
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• v.16 no.1
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• pp.91-104
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• 2003

The purpose of this study is primarily intended to examine the stress and physical, emotional and behavioral stress symptoms of elementary school students supply the basic data of intervention for children's health promotion. The subjects of this study were 616 students who were currently enrolled in 5th and 6th grade elementary school in Jeollabukdo ; 3 schools in J city and other 6 in 3 rural area. The data were collected by self-reported questionnaire from 3rd to 13th April 2002 and collected data were analyzed by SPSS WIN 8.0. The results of this study were as followings. 1. The mean score of stress that children experience was 2.73 and the most stressful factor was a friendship stress. The most frequently experienced stress were feel that a friends would leave them alone. 2. The mean score of stress symptom that children experience was 1.92 and the most stressful symptom was the emotion symptom. The most frequently experienced stressful symptom were feel fatigue of everyday. 3. General characteristics related to stress were showed significantly different according to sex(t=-3.243, p=.001) 4. General characteristics related to stress symptoms were showed significantly different according to sex(t=-2.268, p=.024), family circumstances(F=8.697, p=.000), academic scores(F=11.216, p=.000) and parental concerns on a child(t=-2.561, p=.011). 5. The relation between stress and stress symptoms showed a positive correlation, which was significant statistically(r=.453, p=.000). In conclusion, elementary school students experience various stresses and the stress symptoms have positive close connection with health problems. Therefore, to study the students stress and consequent symptoms further, it is recommended that we should subdivide and analyze the stressor and stress symptoms by proper areas. In the meantime, in order to promote children's health using the data in this study, we should develop the correlated program among individual, family, school and community while we are deeply concerned about and support children continuously.