• 생물정신의학
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• 제9권2호
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• pp.152-158
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• 2002

Background & Purpose:Neuropsychological disorders after traumatic brain injury(TBI) are poorly correlated with structural lesions detected by structural neuroimaging techniques such as computed tomography(CT) scan or magnetic resonance imaging(MRI). It is well known that patients with TBI have cognitive and behavioral disorders even in the absence of structural lesions of the brain. This study investigated whether there are abnormalities of regional cerebral blood flow(rCBF) in TBI patients without structural abnormality on MRI, using technetium 99m ethyl cysteinate dimer(Tc-99m-ECD) single photon emission computed tomography(SPECT) scans. Materials and Methods:Twenty-eight TBI patients without structural abnormality on MRI(mild, n=13/moderate, n=9/severe, n=6) and fifteen normal controls were scanned by SPECT. A voxel-based analysis using statistical parametric mapping(SPM) was performed to compare the patients with the normal controls. Results:rCBF was reduced in the right uncus and the right lateral orbitofrontal gyrus in the TBI patients. However, no increase of rCBF was noted in the patients in comparison to the normal controls. Conclusions:These results suggest that the TBI patients, even in the absence of structural lesion of the brain, may have dysfunction of the brain, particularly of the orbitofrontal and anterior pole of the temporal cortex. They also suggest that SPECT can be a useful method to identify brain dysfunctions in combination with structural brain imaging and neuropsychological tests.

• 동의생리병리학회지
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• 제24권3호
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• pp.476-483
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• 2010

The present study was performed to investigate the putative anxiolytic-like effects of the aqueous extract of the roots of Scrophularia buergeriana (SB-W) using elevated plus-maze (EPM) and hole-board apparatus in mice. SB-W was orally administered at doses of 50, 100, 200 or 400 mg/kg to ICR mice, 1 h before the behavioral evaluation. Control group were administered with an equal volume of saline, and positive control group with buspirone (2 mg/kg, i.p.). The administration of SB-W significantly increased the percentage of time spent in open arms and entries into the open arms of the EPM compared with saline-treated control group (P < 0.05). Futhermore, those anxiolytic-like activities of SB-W were antagonized by flumazenil (a $GABA_A$ antagonist, 10 mg/kg), but not by WAY-100635 (a 5-$HT_{1A}$ antagonist, 0.3 mg/kg). Moreover, there were no changes in the locomotor activity and myorelaxant effects in any group compared with saline-treated control group. In the hole-board test, the administration of SB-W (200 and 400 mg/kg) significantly increased the number of head-dipping compared with saline-treated control group (P < 0.05). Therefore, these findings suggest that Scrophularia buergeriana promotes the anxiolytic-like activity mediated by GABAergic nervous system in mice.

• 대한지역사회영양학회지
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• 제17권4호
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• pp.390-406
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• 2012

Childhood obesity has rapidly increased worldwide and is one of the most serious health problems in this age group. In order to prevent and manage childhood obesity, we developed a nutrition education website. The website consisted of three parts. The first part was made for self-assessment with regard to obesity index, dietary habits, food frequency, dietary attitude, nutrition knowledge, nutrient intake, energy expenditure, and the stage of behavioral change, and tailored messages and advice according to the assessment results. A total of 612 real-size food photos as well as a nutrient database of 3,346 foods and 541 dishes were created to help children estimate nutrient intakes accurately. In addition, an energy expenditure database of 156 activities for children was established to calculate calorie consumption. The second part was made for setting long-term and short-term goals and keeping track of the changes in energy intake and expenditure in one's own page. The third part was made for education. Various types of nutrition information were provided; texts, pictures, calculators and games. The readability and design of the website were evaluated by 46 obese children. Usefulness, design and readability of the website were found to be desirable for children. This website is expected to be used by an obese child alone or with parents or nutrition teachers in order to control body weight through healthy dietary habits and physical activities. In addition, a non-obese child can also use this website for maintaining healthy dietary habits and preventing obesity.

• 패션비즈니스
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• 제11권2호
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• pp.145-154
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• 2007

The purpose of this study is to analyze University Woman Students' recognition of their physical bodies and the effects that their recognition has on their image and satisfaction of their physical bodies. The result of study is as follows. 1) According to the result of the analysis of the difference between University Woman Students students' practical physical sizes and ideal sizes, it was showed that their heights and burst should be larger than their practical physical sizes but their waist, hip, and weight should be reduced.2) According to the result of the analysis of the factors for the evaluation of University Woman Students students' behavioral body images, Factor I was 'Management of Appearance', factor II was 'Management of Weight' and Factor III was 'Satisfaction of Appearance'. Considering the result of correlation of factors of the body images, it was showed that the more interest they had on their appearances, the more management they had on their weights. 3) They had comparatively positive recognition on their physical bodies. However, regarding their degrees of the satisfactions on their physical parts, they showed somewhat dissatisfaction on all the items of their physical parts. 4) According to the result of the analysis of the correlation between their recognition of the physical types and their satisfaction of them, it was showed that they had more satisfactions when their heights were higher and their weights were lighter. In addition, it was showed that they had more satisfaction when they had larger busts and regarding their waists, hips, upper arms, lower arms, wrists, thighs, and calf measurements, they had more satisfactions when they had thinner ones and regarding their shoulders' measurements, it was showed that they had more satisfactions when they had narrower shoulders' measurements.

• 말소리와 음성과학
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• 제3권3호
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• pp.133-140
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• 2011

Muscle misuse dysphonia (MMD) is defined as a behavioral voice disorder resulting from inappropriate contractions of intrinsic and/or extrinsic laryngeal muscles. The purpose of this study was to investigate the effect of motor learning guided laryngeal motor control therapy (MLG-LMCT) which is designed to improve an existing LMT and further the effective voice treatment on people with muscle misuse dysphonia. Forty-six people with MMD (M:F=16:30) participated in this study. The voice samples of the participants were recorded to investigate the effect of MLG-LMCT before and after the voice therapy. Voice samples were analyzed via electro-glotto-graph (EGG). Contact quotient (CQ), speed quotient (SQ), and waveform were reported. In addition, perceptual and acoustical evaluation were conducted to determine the change of voice improvement after treatment. The experimenter massaged the tensioned muscles around the neck. In order to find more proper phonation the experimenter showed the subjects their EGG wave forms as to whether or not they are moving the vocal folds to the appropriate position. Therefore, the EGG wave forms were used as a type of visual feedback. With the wave form, the experimenter helped subjects move the vocal folds and laryngeal muscles to find more proper voice production. The sensory stimuli from the experimenter gradually faded out. A paired dependent t- test revealed that there was significant differences in CQ between pre- and post-therapy. Perceptually, overall, rough, breathy, strain, and transition were significantly reduced. Acoustically, there were significant differences in Fo, jitter, shimmer, and NHR. After using MLG-LMCT, most of the subjects showed improvements in voice quality. The results from this study led us to the following conclusions: Motor learning guided laryngeal motor control therapy (MLG-LMCT) has reduces muscle misuse dysphonia. These results may occur because a visual feedback from EGG wave form can maintain the effect of the muscle tension reduction from laryngeal manual therapy. In case of people with MMD who reduced muscle tension from the therapy (LMT) but, not appropriately manipulating the location of larynx or adducting the vocal folds, MLG-LMCT might be an alternative therapy approach.

• Asian-Australasian Journal of Animal Sciences
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• 제31권8호
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• pp.1098-1102
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• 2018

Objective: Temperament can be defined as a type of behavioral tendency that appears in a relatively stable manner in responses to various external stimuli over time. The aim of this study was to estimate genetic parameters for the records of temperament testing that are used to improve the temperament of Jeju crossbred (Jeju${\times}$Thoroughbred) horses. Methods: This study was conducted using 205 horses (101 females and 104 males) produced between 2010 and 2015. The experimental animals were imprinted and tamed according to the Manual for Horse Taming and Evaluation for Therapeutic Riding Horses and evaluated according to the categories for temperament testing (gentleness, patience, aggressiveness, sensitivity, and friendliness) between 15 months and 18 months of age. Each category was scored on a five-point linear scale. Genetic parameters for the test categories were analyzed using a multi-trait mixed model with repeated records. The ASReml program was used to analyze the data. Results: The heritability of gentleness, patience, aggressiveness, sensitivity and friendliness ranged from 0.08 to 0.53. The standard errors of estimated heritability ranged from 0.13 to 0.17. The test categories showed high genetic correlations with each other, ranging from 0.96 to 0.99 and high repeatability, ranging from 0.70 to 0.73. Conclusion: The results of this study showed that the test categories had moderate heritability and high genetic correlations, but additional studies may be necessary to use the results for the improvement programs of the temperament of Jeju crossbred horses.

• 산업경영시스템학회지
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• 제40권2호
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• pp.68-77
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• 2017

In order to implement the smart home environment, we need an intelligence service platform that learns the user's life style and behavioral patterns, and recommends appropriate services to the user. The intelligence service platform should embed a couple of effective and efficient data mining algorithms for learning from the data that is gathered from the smart home environment. In this study, we evaluate the suitability of data mining algorithms for smart home intelligent service platforms. In order to do this, we first develop an intelligent service scenario for smart home environment, which is utilized to derive functional and technical requirements for data mining algorithms that is equipped in the smart home intelligent service platform. We then evaluate the suitability of several data mining algorithms by employing the analytic hierarchy process technique. Applying the analytical hierarchy process technique, we first score the importance of functional and technical requirements through a hierarchical structure of pairwise comparisons made by experts, and then assess the suitability of data mining algorithms for each functional and technical requirements. There are several studies for smart home service and platforms, but most of the study have focused on a certain smart home service or a certain service platform implementation. In this study, we focus on the general requirements and suitability of data mining algorithms themselves that are equipped in smart home intelligent service platform. As a result, we provide a general guideline to choose appropriate data mining techniques when building a smart home intelligent service platform.

• 대한의용생체공학회:의공학회지
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• 제18권4호
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• pp.485-491
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• 1997

본 논문은 각성상태에 다른 생리신호와 행위신호 및 주관적 평가의 상관관계에 대하여 나타내었다. Nz와 반응시간은 mKSS level 의 변화와 동일한 경향을 나타내는데 반하여 1분당 눈 깜박임 수는 앞의 두 가지 변수와 다른 경향을 나타내었다. 1분당 눈깜박임 수는 mKSS level 1에서 5까지는 낮은 변화율 갖고 mKSS level 7에서는 높은 변화율을 갖는 반면에 mKSS level 9에서는 이와 반대로 변화율이 급격히 감소한다. 피검자들은 서로다른 1분당 눈깜박임 수(EBR)를 가지나 EBR의 변화율은 비슷하였다. 그러므로 EBR의 변화율을 각성판정지표로 사용할 수 있음을 알 수 있었다. 반응시간 실험 결과로부터mKSS level 5이상부터 작업수행능력이 낮아짐을 알 수 있었고 false positive 와 false negative 가 mKSS level3부터 관찰되었으므로 효과적으로 각성제어를 위하여 mKSS level 3과 5사이에 각성상태를 향상시키기 위한 소리나 향기 등의 자극을 주어야 함을 알 수 있었다.

• Journal of Ginseng Research
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• 제35권1호
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• pp.39-44
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• 2011

We studied the acute oral toxicity of black ginseng (BG) produced by heat process in rats. Single acute BG extract doses of 0, 5, 10, and 15 g/kg dissolved in saline were administered by oral gavage and the animals were kept under observation for 14 days. The single administration of BG extract up to 15 g/kg did not produce mortality, behavioral change or abnormal clinical signs in the rats. These results indicated that the oral $LD_{50}$ of the BG extract in the rats is higher than 15 g/kg. Compared to the control group, no treatment-related biologically significant effects of BG extract were noted in the measurements of the body weight or food intake. At the end of the period, the biochemical parameters and hematological parameters were analyzed in the plasma and blood. A histopathological examination of the liver and kidney was also conducted. Only the blood nitrogen urea and potassium levels in the biochemical indices showed significant differences at 10 and 15 g/kg doses of BG extract compared to the control group. These changes were not considered to be due to the toxicity. None of the other clinical chemistry parameters were affected. Therefore, these results indicate that the BG by heat processing is virtually nontoxic.

• 보건교육건강증진학회지
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• 제20권1호
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• pp.187-202
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• 2003

The conveyance of health information through mass media is becoming more popular, even through recreation at television programs. This study aims to investigate the influence of health related TV programs for recreation on a practice action of health behavior. In particular, the relationship between attitude, belief, and behavioral practice of the TV audience is explored. Data was collected from 200 respondents for two weeks in May, 2002. The results showed that the motive of the TV audience for watching TV recreation programs was either entertainment or fun. They satisfied with the programs in general. However, the rate of desirable health behavior practice after watching those programs was low. The degree of practice was significantly correlated with belief, satisfaction, and application possibility of the TV audience to the program. In addition, two personal factors such as gender and subjective evaluation of personal health status were significant in influencing health behavior. The appearance of experts on programs was the most important factor influencing the belief of an audience. This implies that audiences want to have the health information fulfilling scientific evidences. It is suggested that TV recreation programs would be beneficial to most audience members for in receiving important health information, only if recreation and interest factors in the program as well as the evidence-based health information and knowledge are successfully combined.