• Title/Summary/Keyword: Behavioral change

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Effects of Pilocarpine and Kainic Acid on EEG and Behavior Activity in Freely Behaving Rats

  • Choi, Byung-Ju;Cho, Jin-Hwa;Lee, Maangee-G.
    • Biomolecules & Therapeutics
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    • v.4 no.2
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    • pp.167-173
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    • 1996
  • This study was undertaken to evaluate a behavior-electroencephalogram (EEG) pattern relationship in pilocarpine- and kainic acid-induced convulsions of rats. Also we intended to examine the effect of a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, MK-801, and diazepam on the pilocarpine-induced behavioral and electrical seizures in rats. The electrical activities at frontal and hippocampal areas and behavior activities were measured in freely moving rats. At the beginning of the experiments, the rats displayed an exploratory behavior. This awake and moving phase with a low amplitude, irregular, 4-10 Hz wave was followed by a still phase. Pilocarpine (400 mg/kg, i.p.) and kainic acid (0.5 mg/kg, i.c.v.) induced tonic and clonic seizures. The pilocarpine-induced change in electrical activities exhibited a weak correlation with behavioral convulsion at all stages. The amplitude and duration of the electrical response were not linear with the degree of behavioral score. An application of MK-801 (dizocilpine, 7.5 mg/kg) did not affect the amplitudes of the convulsant-induced electrical activities, though the same dose of this drug caused the deformation of the electrical pattern. There was no effect of MK-801 on the behavioral and electrical activities as expected. Diazepam (1 mg/kg) did not affect the amplitude of the electrical activities induced by pilocarpine but changed the pattern of these activities. Our study shows that there is no linear relationship between degree of behavior and amplitude of electrical activities of convulsants. This may indicate that the NMDA receptor stimulation can be processed by the neocortical or hippocampal network in a different way between behavioral and electrical activities.

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The Relationship between Treatment Intention and Compliance in Newly Detected Hypertensive Patients (새로이 발견된 고혈압 환자들의 약물치료 및 생활양식 개선의도와 순응도와의 관계)

  • Bae, Sang-Soo;Lee, Sok-Goo
    • Journal of Preventive Medicine and Public Health
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    • v.34 no.4
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    • pp.417-426
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    • 2001
  • Objectives : To analyse the psychosocial factors associated with hypertension management(drug treatment and life style modification) of newly detected cases and to understand and assess their behavioral intention or behaviors. Methods : The survey area was a combined urban and rural area in Chungnam province, Korea, and the sampling method was cluster sampling. Study subjects included 541 newly detected cases of hypertension rated above stage 2 by JNC-VI from a community survey. The first survey was applied to 383 of these patients in order to discern their psychosocial characteristics. A follow-up survey was given to 345 persons with an 11-month interval following monthly telephone counseling concerning medication and life style modification by trained nurses. The final study subjects for analysis comprised 271 persons after excluding cases of incomplete data and change of address. Results : Among the 85(33.2%) new patients who had intended to undergo drug treatment, 30(35.3%) persons were treated with antihypertensive agent after 11 - month interval, while among the patients with no intention to receive treatment, only 36(21.1%) persons were treated. Hypertensive patients with a high intention score revealed a high score in life style modification compliance as well. Seventy three percent of the variance of behavioral intention to undergo hypertension management was explained by the patients attitude toward performing the behavior and subjective norm associated with behaviors related to the theory of reasoned action in structural modeling. Actual behaviors related positively with behavioral intention. The coefficient of determination was 0.255. Conclusion : Improving the compliance level of hypertensive patients in respect to drug treatment or life style modification requires a build up of positive behavioral intention, and caregivers must pay more attention to eventually converting behavioral intention to actual behaviors.

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Reexamination of Behavioral Activation and Inhibition Scale and Motivation for Self-determination in P·E Class (체육수업 상황에서 행동활성화와 억제 척도의 재검증과 자기결정성 동기의 관계)

  • Choi, Hun-Hyuk;Huh, Jin-Young
    • 한국체육학회지인문사회과학편
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    • v.51 no.5
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    • pp.229-241
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    • 2012
  • The purpose of this study was to identify the reexamination effects of behavioral activation·inhibition scale(Choi & Huh, 2010) on self-determination in order to analysis situational structure for P·E class which is perceived by students. To obtain the purpose, 656 high-school students from Gyeonggi-do area answered questionnaire using convenient sampling method. Data which is obtained through self-administration was analyzed using by the frequency analysis, multiple reguression analysis, EFA, and CFA with SPSS 18.0 and AMOS 16. Results were as followed. First, the more students have friend relation, teacher behavior, emotion change, and positive class attitude that are sub-factors of behavioral activation·inhibition, the more they have self-determination. Second, the less students have typical class structure, negative teacher's attitude, punishment, and lack of self-efficacy, the more they have self-determination. Overall results were discussed for practical application in P·E class.

Evaluation on Effectiveness of Public Health Personnel Training (보건요원 교육효과 평가)

  • Hwang Keum-Bok;Jeon Mi-Soon;Kim Tae-Sook;Yang Byung-Guk;Jeong Eun-Kyung;Yang Sook-Ja;Kim Kwuy-Hyang
    • The Journal of Korean Academic Society of Nursing Education
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    • v.5 no.1
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    • pp.118-132
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    • 1999
  • To improve the effectiveness and efficiency of public health personnel training, we evaluated not only how appropriate the students felt the objectives, contents, methods and multimedia used in the train ing courses, but also how much the students accomplished the objectives and applied skill and knowledge to their own works. We selected 5 courses for the study : Tuberculosis control, Radiological technique, Public health information, Immunization, Mental health management courses used by Kirkpatrick's evaluation model. Reaction evaluation was carried out in final day by questionnaire. The results showed that all of them were very satisfied with educational input and curricula, learn Ing environment. Secondly, we measured the degree of learning achievement on pre and post training by questionaire of specific behavioral objectives. The degree of learning achievement was statistically higher just after training than pre training (paired t-test, p<0.01). Thirdly, evaluation of behavioral change to job was conducted to find out how much students applied skill and knowledge to their own job in 3 months after training by questionnaire. The results of behavioral change evaluation showed that 43.5% of the students who were performing job related with the training courses in 3 months after training applied the learned skill and knowledge to their own job quite well and 37.8% of them applied relatively well, therefore total 81.4% of them applied to their own job. And effectiveness of training for the above mentioned students showed that 41.9 % of them had improved or enforced their jobs after training, 35.5% of them had had no remarkable changes, and 15.7% had newly applied the learned skill and knowledge to their jobs. For evaluating the degree of usefulness of material predistribution in two weeks before training, we compared experimental groups with control groups. The results showed that general reactions are helpful but the degree of learning achievement is no discrepancy.

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School-based Health Promotion Program for Prevention of Cardiovascular Disease: Healthy Life for School-Aged Children

  • Choi, Bo-Yul
    • Korean Journal of Health Education and Promotion
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    • v.3 no.1
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    • pp.21-37
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    • 2001
  • Over the past few decades, dramatic socioeconomic developments have resulted in the change of epidemiological transition from infectious to chronic diseases as leading causes of death in Korea$^{1)}$ . Behavioral factors, particularly smoking, diet and activity patterns, alcohol consumptions are among the most prominent contributors to mortality.(omitted)

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Effect of Herbal-Acupuncture on Repeated Cocaine-induced Behavioral Sensitization in the Rat (약침이 반복적인 코카인 투여로 인한 행동적 민감화 현상에 미치는 효과)

  • Lee, B.B;Yang, C.H.;Hahm, D.H.;Lee, H.J.;Shim, I.S.
    • Journal of Pharmacopuncture
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    • v.7 no.1 s.12
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    • pp.53-61
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    • 2004
  • Substantial evidence suggests that behavioral and reinforcing effects of cocaine can be mediated by the mesolimbic dopaminergic system. It has been shown that repeated injections of cocaine produce increase in locomotor activity, expression of the immediate-early gene, c-fos in the nucleus accumbens (NAc), which was one of the main dopaminergic terminal areas. Herbal-acupuncture as a therapeutic intervention has been widely used for the treatment of many functional disorders such as drug abuse. Coptidis Rhizoma (CR) and its main component, berberine (BER) were selected as herbal medicine of herbal-acupuncture. Both medicines have been known to have the therapeutic effect on the central nervous system. In order to investigate the effects of CR and BER herbalacupuncture at shenmen (HT7) point (CR/H and BER/H) on the cocaine-induced behavioral sensitization, the influence of CR/H and BER/H on repeated cocaine-induced locomotor activity, the change of c-Fos expression in the brain by immunohistochemistry were examined. Male SD rats were given CR/H (0.4mg/kg) and BER/H (0.1mg/kg) 30 min before daily injections of cocaine hydrochloride (15mg/kg. i.p.) 10 days. After 3 days withdrawal, rats received a challenge injection of cocaine (15mg/kg, i.p.). Systemic challenge with cocaine produced much larger increased locomotor activity, accumbal Fos-like immunoreactivity in the NAc. Pretreatment with CR/H and BER/H significantly inhibited cocaine-induced locomotor activity, the change of c-Fos expression in the rats. Our data demonstrated that the inhibitory effects of cocaine-induced behavioral sensitization by CR/H and BER/H were closely associated with the reduction of presynaptic dopamine release in the NAc. These results suggest that CR/H and BER/H can be effectively applied to cocaine addiction.

A Study on Attitude Change in School Health Education (학교보건교육(學校保健敎育)에 있어서의 태도변화(態度變化)에 관(關)한 연구(硏究))

  • Moon, Jae Woo
    • Journal of the Korean Society of School Health
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    • v.4 no.2
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    • pp.146-158
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    • 1991
  • There is no doubt that the school health education in school health services is the most important component. But the concept and scope of the school health education is still not recognized and accepted satisfactorily in Korea. It is generally accepted that health education is a process of changing of attitude and behavior forward health practice. The term attitude refers to certain regularities on the part of an individual in feelings, thoughts, and predispositions to act toward some aspect of his environment. Attitudes have three components: affective, cognitive, and behavioral. The strategies of attitude change in school health education consist of incentive, justification, and coersion. In this study I explained reinforcement and motivation as the strategies of attitude change. The attitude change is not built in a day. When the teachers give the pupils knowledge, comprehension, or skill through school health education proper to each stage, then the attitude change will be realized.

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The Change of the Internal World in Middle School Girls Having Emotional and Behavioral Difficulties by Exploring Their Sandplay (모래놀이를 통해 본 정서·행동에 어려움이 있는 여중생의 내면세계의 변화)

  • Jang, Mi Ja;Sim, Hee-og
    • Korean Journal of Child Studies
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    • v.38 no.1
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    • pp.95-116
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    • 2017
  • Objective: Middle school girls who belonged to the concerned group in their school assessment were treated by sandplay for relieving their emotional and behavioral difficulties. The purpose of this study was to explore the change of the internal world of the girls through sandplay. Methods: Analytical psychology and sandplay theories were used for this exploration, especially Turner's (2005) content themes in sandplay. The participants were four first-grade girls. Pre-test measures, a 12-session sandplay program, and post-test measures were administered. Results: For the first girl, the initial phase was 1-6 (time trip), the intermediate phase was 7-9 (seeking for an inner island), and the final phase was 10-12 (seeking for a real stone). For the second girl, the initial phase was 1-5 (my heart was like cold weather), the intermediate phase was 6-10 (fallen, sick, and risen), and the final phase was 11-12 (trophy given to me). For the third girl, the initial phase was 1-5 (seeking for oasis), the intermediate phase was 6-10 (difficult trip for climbing with camel), and the final phase was 11-12 (discovering oasis). For the fourth girl, the initial phase was 1-3 (an island drowning shortly ), the intermediate phase was 4-10 (my unknowable mind), and the final phase was 11-12 (a tree growing well). Conclusion: This study showed psychological phenomena in the sandplay of four girls such as opposites and the union of masculinity and femininity as they explored their own identity. Drawing tests and counselling objects indicated positive changes; thus, these findings support the effectiveness of sandplay therapy for transforming the psyche of middle school girls.

A Study of the Employee's Attitude Toward Operation of the Hospital Material Requirements Planning System(HMRPS) in University Hospitals (병원 종합 물류시스템 운영에 대한 관련직원들의 인식)

  • Lee, Kwang-Yong;Yu, Seung-Hum;Sohn, Tae-Yong
    • Korea Journal of Hospital Management
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    • v.4 no.2
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    • pp.266-285
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    • 1999
  • The purpose of this study is to identify influencing factors for successful introduction, implementation and management of HMRPS through assessment of the employees attitude toward HMRPS in technical, administrative, and organization behavioral areas. Data were collected from 157 HMRPS employee members' self-reporting questionnaire in three university hospitals in the city of Seoul and Kyonggi Province from November 5 to November 10, 1997. Relevant literature on industry company MPR system theory was reviewed to develop the theoretical framework. The results were as follows: The employee's recognition of tangible benefit were more significantly influenced success than intangible benefit for successful operation relating the HMRPS. Concerning the employee's recognition of the successful HMRPS and the factor of influenced success was significantly positive correlation between tangible and intangible benefits and success factor in technical, administrative, and organizational behavior area. This study showed that major factor affecting the employee's recognition of tangible and intangible benefit for successful HMRPS. For tangible benefits; Success factors in the technical areas were quality of the data and information, efficiency of inventory management and rescheduling of operation plan. Success factors in the administrative areas were: role of top management. Success factors in the organization behavioral areas were; simplicity of the HMRPS, human resistance to change. For intangible benefits; Success factors in the organization behavioral areas were; user involvement, simplicity of HMRPS, human resistance to change. Futhermore as the exact evaluation of successful factors of HMRPS implement is needed, research for the development of systemic variables of physical distribution system control, methods, capacity of system, duration and other environment in many of 30 hospitals or more, and for the empirical study for HMRPS.

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