• Asian Pacific Journal of Cancer Prevention
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• 제16권8호
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• pp.3147-3152
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• 2015

Background: Phylloides tumors are rare breast neoplasms with a variable clinical course depending on the tumor category. Along with histologic features, the role of immunohistochemical staining has been studied in predicting their behavior. Objectives: Our aim was to evaluate the role of CD 10 immunohistochemical staining in predicting survival, recurrence and metastasis in phylloides tumor. We also evaluated correlations of other clinicopathological features with overall and disease-free survival. Materials and Methods: CD10 expression was studied in 82 phylloides tumors divided into recurrent/metastatic and non-recurrent/non-metastatic cohorts. The Chi-square test was applied to determine the significance of differences in CD10 expression between outcome cohorts. Uni and multivariate survival analyses were also performed using log-rank test and Cox regression hazard models. Results: All 3 metastatic cases, 5 out of 6 (83.3%) recurrent cases and 37out of 73 (50.7%) non-recurrent and non-metastatic cases expressed significant (2+ or 3+) staining for CD10. This expression significantly varied between outcome cohorts (p<0.03). Tumor category and histological features including mitotic count and necrosis correlated significantly with recurrence and metastasis. A significant decrease in overall and disease free survival was seen with CD10 positivity, malignant category, increased mitoses and necrosis. Neither CD10 expression nor any other clinicopathologic feature proved to be an independent prognostic indicator in multivariate analysis. Conclusions: CD10 immunohistochemical staining can be used as a predictive tool for phylloides tumor but this expression should be interpreted in conjunction with tumor category.

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2003년도 추계국제학술대회
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• pp.91-93
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• 2003

It has been estimated that the equivalent of approximately $US 50 billion has been spent on research on the behavior and fate of pesticides in the environment since Rachel Carson published “Silent Spring” in 1962. Much of the resulting knowledge has been summarized explicitly in computer algorithms in a variety of empirical, deterministic, and probabilistic simulation models. These models describe and predict the transport, degradation and resultant concentrations of pesticides in various compartments of the environment during and after application. In many cases the known errors of model predictions are large. For this reason they are typically designed to be “conservative”, i.e., err on the side of over-prediction of concentrations in order to err on the side of safety. These predictions are then compared with toxicity data, from tests of the pesticide on a series of standard representative biota, including terrestrial and aquatic indicator species and higher animals (e.g., wildlife and humans). The models' predictions are good enough in some cases to provide screening of those compounds which are very unlikely to do harm, and to indicate those compounds which must be investigated further. If further investigation is indicated a more detailed (and therefore more complicated) model may be employed to give a better estimate, or field experiments may be required. A model may be used to explore “what if” questions leading to possible alternative pesticide usage patterns which give lower potential environmental concentrations and allowable exposures. We are currently at a maturing stage in this research where the knowledge base of pesticide behavior in the environmental is growing more slowly than in the past. However, innovative uses are being made of the explosion in available computer technology to use models to take ever more advantage of the knowledge we have. In this presentation, current developments in the state of the art as practiced in North America and Europe will be presented. Specifically, we will look at the efforts of the ‘Focus’ consortium in the European Union, and the ‘EMWG’ consortium in North America. These groups have been innovative in developing a process and mechanisms for discussion amongst academic, agriculture, industry and regulatory scientists, for consensus adoption of research advances into risk management methodology.

• 한국농촌간호학회지
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• 제1권1호
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• pp.21-31
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• 2006

Purpose: This purpose of this study was to examine the effect of a walking exercise program on blood pressure and related factors in older patients with hypertension living in rural areas. Method: The participants were 233 patients with hypertension, 60years or age or over, who were registered at one of 36 public health centers in North Chung Cheong Province and agreed to participate in this study. The program was implemented for 12 weeks from Dec. 2005to Feb. 2006. The data were collected before and right after the program and paired t-test was used to analyze the data. Analysis was done with the SPSS program. Result: Systolic pressure (t=7.460, p=0.000) and diastolic pressure (t=5.309, p=0.000) decreased significantly. Total cholesterol l (t=-9.991, p=0.000), LDL cholesterol and HDL cholesterol (t=-3.180, p=0.000) all increased significantly. There was no change in weight or obesity level. Blood sugar (t=2.218, p=0.028) decreased significantly. Knowledge of hypertension increased significantly as did the self-care behavior of these patients with hypertension. Conclusion: The walking exercise program was found to be effective to control blood pressure in older patients with hypertension in rural areas and to help HDL cholesterol, knowledge of hypertension, and self-care behavior of hypertension increase greatly, while blood sugar level decreased.

• 대한간호학회지
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• 제16권2호
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• pp.44-52
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• 1986

Maternal and child health(MCH) status is considered as an important indicator of the level of health and civilization of a community and a country. MCH services for the rural population in the remote ar deserves priority by the government, since more than half(52.9%) of the delivery was occured at home and almost half (45.5%) of the delivery was assited by family members or neighbors. The purpose of the study was to analyse the health fare behavior related to pregnancy and delivery, which can be contributed maternal health care policy mating for the rural people. Specifically, it was intended to analyze the variables which affect the health care behavior in selecting birth places and birth attendants. This study utilized the data which had been already collected for an experimental study on primary health program model in Korean rural communities, funded by the USAID. 184 sample households with women who had delivered a baby during March 1982 to February 1983 were selected. Discriminant Analysis was employed for statistical analysis by utilizing SPSS computer package program. Birth places and birth attendants were considered as dependent variables. Among 12 independent variables in 5 groups considered, 7 independent variables were found statistically significant to affect the selection of birth place. Significant variables by the order of importance are mother's age, order of baby, number of prenatal care, accessibility of emergency medical care, coverage of medical insurance, mother's membership in community organization and husband's educational level. The degree of correct classification of the grouped cases by employing a discriminant . analysis was significantly improved to 78.2％ in comparison to Cmax（56%) and Cpro(51%). Policy implications for each significant variable were discussed to improve the maternal and child health. in Korean ruralarea.

• 디지털융복합연구
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• 제19권2호
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• pp.143-150
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• 2021

그 동안 수 많은 마케팅 분야 연구들은 충동구매로 대표되는 소비자의 충동적인 행동을 유발하는 요인에 대해 주목해왔다. 이들은 문화적 차이와 성격적 특성, 개인의 물질주의 및 위험추구 성향 등 다양한 변수들에 대해 탐색했다. 본 연구는 그간 선행연구들이 거의 다룬 적이 없으나, 소비자의 특성으로서 소비 상황에서 받게 되는 소비자의 신체적 자극에 주목하였다. 구체적으로, 저자들은 소비자가 인지적 자원의 고갈을 유발할 수 있는 감각적 자극으로서 갈증의 영향을 살펴보았다. 두 번의 걸친 실험의 결과는, 소비자가 갈증을 느낄 경우 충동구매가 일어날 가능성이 높음을 보였고(실험 1), 이 같은 갈증과 충동구매 간 관계에 자기통제의 저하가 기저에 있음을 보였다(실험 2). 이는, 물리적 자극으로서의 갈증이 인지적인 자원의 고갈을 이끌고, 이것이 자기통제력의 약화로 이어져 충동구매를 증가시키는 것을 의미하며, 결국 이를 통해 최근 코로나19로 인한 사회적 현상인 충동구매에 대한 완화를 이끌 수 있을 것으로 본다.

• 정보보호학회논문지
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• 제31권6호
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• pp.1105-1114
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• 2021

최근 급상승한 암호 화폐의 인기로 인해 암호 화폐 채굴 악성코드인 크립토재킹 위협이 증가하고 있다. 특히 웹 기반 크립토재킹은 피해자가 웹 사이트에 접속만 하여도 피해자의 PC 자원을 사용해 암호 화폐를 채굴할 수 있으며 간단하게 채굴 스크립트만 추가하면 되기 때문에 공격이 쉽고 성능 열화와 고장의 원인이 된다. 크립토재킹은 피해자가 피해 상황을 인지하기 어렵기 때문에 크립토재킹을 효율적으로 탐지하고 차단할 수 있는 연구가 필요하다. 본 연구에서는 크립토재킹의 대표적인 감염 증상과 스크립트를 지표로 활용하여 효과적으로 크립토재킹을 탐지하는 프레임워크를 제안하고 평가한다. 제안한 크립토재킹 탐지 프레임워크에서 행위 기반 동적 분석 기법으로 컴퓨터 성능 지표를 학습한 K-Nearest Neighbors(KNN) 모델을 활용했고, 스크립트 유사도 기반 정적 분석 기법은 악성 스크립트 단어 빈도수를 학습한 K-means 모델을 크립토재킹 탐지에 활용했다. 실험 결과에 따르면 KNN 모델은 99.6%의 정확도를 보였고, K-means 모델은 정상 군집의 실루엣 계수가 0.61인 것을 확인하였다.

• 한국수산과학회지
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• 제56권4호
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• pp.541-548
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• 2023

Behavior serves as an important indicator of the effects of environmental stressors on organisms. In this study, one-year-old abalone Haliotis discus hannai (15.1±0.8 mm) were used and each 0.34 m2 tank was stocked with 100, 150, 200, 250, and 300 juvenile abalone. After 328 days, we found that the low stocking density treatment showed significantly higher growth, whereas the high stocking density treatment showed significantly lower growth. In addition, abalone showed a lower rate of movement, distance moved, and velocity at higher stocking densities, but only velocity differed significantly. In contrast, In the Supplied the feed tanks significant difference between the moving distance and velocity. When the two groups of different sizes were mixed in tank, the rate of movement, distance moned, and velocity showed significant differences between differently-sized indivisuals. Our study indicates that breeding abalone at high densities has a negative effect on their growth and survival, which is thought to primarily be caused by spatial competition, and secondarily by differences in body size, ultimately affecting growth and productivity.

• 전력전자학회논문지
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• 제24권6호
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• pp.419-427
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• 2019

Several multilevel converter topologies have been proposed and compared. The three-level (3L) neutral-point-clamped (NPC) topology is promising and widely accepted. However, this topology suffers from uneven loss distribution among switches due to its fixed switching strategy. The 3L active NPC (ANPC) topology, which exhibits improved loss distribution profile, was proposed to address this disadvantage. The 3L T-NPC topology, a hybrid configuration of 2L and 3L NPC topologies, was introduced to address not only the loss distribution problem but also the reduction in the number of switches. In the present research, the application of these three topologies in PMSG-based medium-voltage wind turbines was investigated. The power devices considered were 10 kV IGCTs. Performance was evaluated in terms of a power loss of 10 kV IGCT for each NPC topology, which is a crucial indicator of thermal behavior, reliability, cost, and lifetime of any converter. The comparison was performed using ABB make 10 kV IGCT 5SHY17L9000 and the simulation tool PLECS.

• Geomechanics and Engineering
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• 제14권6호
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• pp.563-570
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• 2018

Ballast layer has an important role in vertical stiffness and stability of railway track. In most of the Middle East countries and some of the Asian ones, significant parts of railway lines pass through desert areas where the track (particularly ballast layer) is contaminated with sands. Despite considerable number of derailments reported in the sand contaminated tracks, there is a lack of sufficient studies on the influences of sand contamination on the ballast vertical stiffness as the main indicator of track stability. Addressing this limitation, the effects of sand contamination on the mechanical behavior of ballast were experimentally investigated. For this purpose, laboratory tests (plate load test) on ballast samples with different levels of sand contamination were carried out. The results obtained were analyzed leading to derive mathematical expressions for the strain modulus ($E_V$) as a function of the ballast level of contamination. The $E_V$ was used as an index for evaluation of the load-deformation characteristics and bearing capacity of track substructure. The critical limit of sand contamination, after which the $E_V$ of the ballast reduces drastically, was obtained. It was shown that the obtained research results improve the current track maintenance approach by providing key guides for the optimization of ballast maintenance planning (the timing of ballast cleaning or renewal).

• Journal of Preventive Medicine and Public Health
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• 제38권3호
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• pp.337-344
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• 2005

Objectives : Job insecurity, such as non-standard work, is reported to have an adverse impact on health, regardless of health behaviors. The aim of this study was to examine the relationship between non-standard employment and health in Korea. Methods : We analyzed a representative weighted sample, which consisted of 2,112 men and 1,237 women, aged 15-64, from the 1998 Korea National Health and Nutrition Examination Survey. Non-standard employment included part-time permanent, short time temporary and daily workers. Self-reported health was used as a health indicator. Results : This study indicated that women were more likely to report poorer health than men with standard jobs. Of all employees, 20.3% were female manual workers. After adjusting for potential confounders, such as age, education, equivalent income, marital, social and self-reported economic status and health behavior factors, nonstandard employment was found to be significantly associated with poor health among female manual workers (OR, 1.86; 95% CI, 1.24 to 2.79). No significant association was found in other working groups Conclusions : Among female manual workers, nonstandard employees reported significantly poorer health compared with standard workers. This result raises concern as there are increasing numbers of non-standard workers, particularly females.