• The Journal of Internal Korean Medicine
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• v.28 no.3
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• pp.597-607
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• 2007

Backgrounds and Objectives: Primary hyperhidrosis deeply affect a patient's quality of life, resulting in impairments of daily activities, social interactions and occupational activities. The objectives of the study were to assess quality of life(QOL) in patients with primary hyperhidrosis before and after treatment with oriental medicine. Methods : Between December 2006 and July 2007, 26 patients underwent oriental medicine treatment. which consisted of herb medicine. acupuncture and iontophosis (if palmar/plantar hyperhidrosis) treatment. QOL questionnaires comprised of dermatology life quality index (DLQI) and visual analogue scale (VAS) were employed before and after treatment Results : All 26 patients were evaluated. The treatment controlled primary hyperhidrosis in 84.6% of cases. The mean of DLQI score before treatment was 16.65 after treatment mean DLQI score was 8.18. The mean of VAS before treatment was 91.35 after treatment mean VAS was 49.92. QOL in patients with primary hyperhidrosis significantly improved after oriental medicine treatment. The improvements in QOL were similar in patientswith palmar/plantar, head, and systemic hyperhidrosis. Conclusions : Oriental medicine treatment leads to significantly improved QOL in patients with primary hyperhidrosis. Further studies are needed to evaluate the objective efficacy in patients with primary hyperhidrosis before and after oriental medicine treatment.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.7
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• pp.4205-4208
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• 2013

Objective: The aim of this study was to explore change and significance of serum carcino-embryonic antigen (CEA) before and after gefitinib therapy in patients with advanced non-small-cell lung cancer (NSCLC). Methods: Forty patients with advanced NSCLCs in III~IV stages were selected as study objects given gefitinib therapy combined with routine local radiotherapy until tumor progression or intolerable toxicity. After treatment, all patients were divided into control and non-control groups according to the results of evaluation based on RECIST 1.1 (Response Evaluation Criteria in Solid Tumors in 2009). Peripheral fasting blood from all patients was collected in the early morning and serum CEA was assessed by electro-chemiluminescence immunoassay (ECLIA) before and after treatment. Before treatment, patients were divided into high CEA group (CEA level > 50 ng/mL) and low CEA group (CEA level ${\leq}$ 50 ng/mL). Adverse reactions were noted and progression-free survival (PFS) in both groups was recorded after long-term follow-up that ended in December, 2012. Results: There was no difference between control and non-control groups in CEA level before treatment (P>0.05), whereas serum CEA decreased more markedly lower in the control group after treatment (P<0.01). All patients were divided into high CEA group (26) and low CEA group (14) according to serum CEA level. There was no statistically significant difference between two groups in adverse reactions (P>0.05) but the rate in former group was lower. Additionally, survival rates at 9 and 12 months in high CEA group were clearly higher than in the low CEA group (P<0.01). Conclusions: Serum CEA level can serve as a biochemical index to evaluate the prognosis with gefitinib treatment for NSCLC.

• International Journal of Highway Engineering
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• v.14 no.5
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• pp.165-177
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• 2012

PURPOSES: The number of traffic accidents in 2010 was 226,978 in Korea, a high percentage of which up to 12.61% was due to drunk driving. As it is expected that the number of traffic accidents will increase because of the drastic increase of the number of vehicle registrations and the prevalent drinking cultures, it is necessary to understand the driving characteristics of drunken drivers to lower the increasing rate. METHODS: This study, therefore, comparatively analyzes the two groups - one group before drinking and the other after drinking - based on the graph, and implements the correlation in each scenario(1,2,3). scenario 1. appearance of jaywalkers; scenario 2. appearance of an illegal left-turning car; and scenario 3. appearance of a vehicle and a person as obstacles to the driver after an accident. RESULTS: The comparative analysis of speed shows that the group after drinking was 50km/h faster than the group before drinking in Scenario 1, 20km/h in Scenario 2, and 15km/h in Scenario 3 respectively. In the comparative analysis of acceleration, the average level of the group after drinking was 0.15 higher than that of the group before drinking in Scenario 1, 0.30 in Scenario 2, and 0.15 in Scenario 3. In the comparative analysis of deceleration, the average level of the group after drinking was about 0.4 lower than that of the group before drinking in Scenario 1, 0.35 in Scenario 2, and 0.2 in Scenario 3 respectively. In the comparative analyses, the item of speed, acceleration and deceleration was of significance for each group in Scenarios. CONCLUSIONS: The comparative analysis demonstrated that there is a difference between the group before drinking and the group after drinking. In the analysis of correlation in each group, it was proved that the drunken group was of significance.

• The Journal of Fisheries Business Administration
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• v.45 no.2
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• pp.29-38
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• 2014

This study is to analyse the timing of the structural change of price volatility and the asymmetry of price volatility during the period before and after the timing of the structural change of price volatility using Jeju Farming Olive Flounder's production area market price data from January 1, 2007 to June 30, 2013. The analysis methods of Quandt-Andrews break point test and Threshold GARCH model are employed. The empirical results of this study are summarized as follows: First, the result of Quandt-Andrews break point test shows that a single structural change in price volatility occurred on May 4, 2010 over the sample period. Second, during the period before structural change, daily price change rate has averagely positive value which means price increase, but during the period after structural change daily price change rate has averagely negative value which means price decrease. Also, daily volatility of price change rate during the period before structural change is higher than during the period after structural change. This indicates that price volatility decreases after structural change. Third, the estimation results of Threshold GARCH Model show that the volatility response against price increase is larger during the period after structural change than during the period before structural change. Also the result shows the volatility response against price decrease is larger during the period after structural change than during the period before structural change. And, irrespective of the timing of structural change, price increase has an larger effect on volatility than price decrease. This means volatility is asymmetric at price increase.

• Journal of Dental Anesthesia and Pain Medicine
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• v.20 no.5
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• pp.313-323
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• 2020

Background: Previous studies have investigated the effects of dexamethasone injections into the pterygomandibular space and compared them to those of controls; however, the effects of dexamethasone injections before and after lower third molar surgery on postoperative complications have not been studied. This research investigated the postoperative sequelae of dexamethasone injections before and after surgery into the pterygomandibular space. The aim of this study was to evaluate the effects of preoperative and postoperative injections of 4 mg of dexamethasone into the pterygomandibular space on postoperative pain, facial swelling, and the restriction of mouth opening following lower third molar surgical removal. Methods: Twenty-seven participants with bilateral symmetrical lower impacted third molars were included in this study. Each participant was randomly allocated to one of two groups. Group A received injections of 1 ml dexamethasone (4 mg/mL) and 1 mL placebo into the pterygomandibular space before and after surgery, respectively. Group B received the same doses of placebo before surgery and dexamethasone after surgery. Results: A significant restriction of mouth opening on the second postoperative day was observed in both groups. Nonetheless, the postoperative restriction of mouth opening, facial swelling, postoperative pain, and analgesic consumption after lower third molar surgical removal were not significantly different in the two groups. Conclusions: Regardless of the time of administration, dexamethasone injections into the pterygomandibular space resulted in satisfactory control of the postoperative sequelae of the mandibular third molar surgical removal.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.3
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• pp.247-256
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• 2022

Purpose : The purpose of this study was to investigate the effects of Kaltenborn-Evjenth (KE) joint mobilization of the distal radioulnar joints (RUJ) and proximal RUJ in distal radius fractures (DRFs) on range of motion (ROM), grip strength (GS), and patient-written wrist evaluation (PRWE) in each group once, thrice, or fivefold. Methods : Forty-two subjects participated in this study. We divided the subjects with DRFs into groups applying KE concepts RUJ mobilization once, thrice, and fivefold. The patients' ROM and GS were measured using a joint goniometer and dynamometer, respectively. Pain and function were also assessed using a PRWE. In the statistical analysis, all data were tested for normality using the Shapiro-Wilk test, and paired t-tests were performed for within-group before-and-after comparisons of each intervention. One-way analysis of variance was used for between-group comparisons of differences. All statistical significance levels were set at α=.05. Results : There were significant differences in the ROM in all three groups before and after the intervention (p<.05), but there were no significant differences between the groups. There were significant differences in the GS in the three groups before and after the intervention (p<.05), but there were no significant differences between the groups. In the pain part of the PRWE, all three groups had significant differences before and after intervention (p<.05), but there was no significant difference between the groups. In the functional part of the PRWE, there were significant differences in the three groups before and after intervention (p<.05), but no significant difference occurred between the groups. Conclusion : Based on the aforementioned results, there were no significant between-group differences in ROM, GS, and PRWE (pain and function) after the application of the K-E joint mobilization to DRFs once, thrice, and fivefold. Nevertheless, there were significant within-group differences in all the above.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.3
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• pp.19-35
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• 2021

Purpose : Recently, there has been a growing social interest in aging well. Consequently, wellness tourism has begun to attract attention. However, no studies on whether wellness tourism has any objective health benefits have been carried out yet. In this study, we assess the health benefits as well as the degree of improvement in health of a wellness tourism program. Methods : The study involved 30 adults over the age of 19 who live in the Gyeongsangnam-do region. Participants were evaluated on health indicator before and after participating in wellness tourism program. Participants took heart rate variability (HRV) test, and LFT, RFT, CBC, FBS HbA1C, and CRP test were conducted before and after the tour. Additionally, a survey was conducted before and after the program, and participant satisfaction was evaluated. Statistical differences in the tests conducted before and after the program were analyzed using a design t-test, a Wilcoxon signed-rank test, and McNemar's test. Results : The study showed that participants were very satisfied with and had significant health improvements after the wellness tourism program. The program was also found to be beneficial in improving participants' emotions as follows: BDI (p<.001), fatigue recovery (p=.006), stress relief (p=.003), improved quality of life (p<.05), and improved sleep quality (p<.001). Conclusion : Wellness tourism programs are specifically beneficial for improving participants' emotions (depression, anxiety), fatigue, stress levels, quality of life, and sleep. Therefore, they are beneficial to the overall health. Further research in the future by way of a follow-up study on the long-term effects on health after short-term interventions will provide more validation data.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.4
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• pp.11-18
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• 2021

Purpose : The purpose of this study was to investigate the effect on lung capacity of healthy men and women in their twenties by performing an intervention using the chest extension exercise and the bridge exercise, which are respiratory muscle strengthening exercises. Methods : Thirty adult men and women in their 20s participated in this study. All subjects participated in the study after hearing the explanation of the purpose and method of the study, filling out a consent form. All subjects were randomly assigned to the chest extension exercise (CEE) group and the bridge exercise (BE) group of fifteen each. Each exercise was performed twice a week for 4 weeks. Lung capacity was measured by forced vital capacity (FVC) and forced expiratory volume in one second (FEV₁) using spirometry. Lung capacity was measured before and after exercise. The measured data were compared through the dependent t-test and the independent t-test. The statistical significance level was set at .05. Results : After the intervention, the CEE group showed a significant increase in FVC and FEV₁ compared to before the intervention (p<.05). After the intervention, the BE group also had a significant increase in FVC and FEV₁ compared to before the intervention (p<.05). However, there was no difference in FVC and FEV₁ between groups before and after the intervention (p>.05). Conclusion : There was no difference between groups in lung capacity after exercise. However, both the chest extension exercise and the bridge exercise increased FVC and FEV1, which was thought to be because both exercise methods were effective in increasing lung capacity. Therefore, both chest extension exercises and bridge exercises can be effectively applied as a way to increase lung capacity.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.2
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• pp.109-117
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• 2023

Purpose : Transcranial direct current stimulation is noninvasive method of cerebral cortical stimulation applied as an intervention to facilitate recovery in stroke patients. The purpose of this study was to examine the effects of transcranial direct current stimulation on depression and anxiety in stroke patients with the aim to finding a reliable method to reduce depression and anxiety in stroke patients. Methods : This study was conducted at A hospital located in D city from December 2022 to February 2023. Patients diagnosed with stroke were selected according to predefined study criteria and divided into two groups. 9 patients in experimental group underwent transcranial direct current stimulation and traditional occupational therapy, while 9 patients in the control group underwent sham transcranial direct current stimulation and traditional occupational therapy for 20 min per session 3 times per week for a total of 8 weeks. Beck depression inventory (BDI) and Beck anxiety inventory (BAI) were used to evaluate depression and anxiety in the patients before and after intervention. Wilcoxon signed rank test was used to compare differences before to after intervention. Mann-Whitney U test was used to compare the two groups. Differences with p<.05 were considered statistically significant. Results : First, both the experimental and control groups presented significant statistical difference before and after intervention on depression (p<.01). Comparison of two groups after intervention showed significant statistical difference in depression (p<.05). Second, the groups presented significant statistical difference before and after intervention on anxiety (p<.01). After intervention, the two groups showed significant statistical difference in anxiety (p<.05). Conclusion : Results of the present study demonstrated the effects of transcranial direct current stimulation on depression and anxiety in stroke patients, suggesting it may be a useful method of rehabilitation in this patient population; as such, further studies are warranted.

• Journal of East-West Nursing Research
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• v.10 no.1
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• pp.68-74
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• 2004

Purpose: This study aims to identify changing image of nurse before and after the first clinical experience, and before graduate. Method: The subjects were 69 nursing students. All of them had their first clinical experience for 1 week during sophomore year. The Nurse's Image was measured before and after the 1st clinical experience, and before graduation. Collected data were analyzed by using repeated measure ANOVA and pair wise comparison method. Results: 1. The mean score for the Nurse's Image overall held by after 1st clinical experience($3.78{\pm}.38$) was more positive than those held by before graduation($3.50{\pm}.49$) and before 1st clinical experience($3.35{\pm}.36$). 2. For the four subscales (F=25.673 p= .000), the mean score of traditional(F=10.394 P= .000), Social(F=11.673 P= .000), Professional(F=17.341 P= .000) and personal Image(F=19.463 P= .000) were more positive than before graduation and before 1st clinical experience. Conclusion: Summarizing, after the nursing students had their 1st clinical training, the nurse's image perceived by them was positively improved compared to before the training. However, by the time of graduation the improved nurse's image was declined back. Therefore it is necessary to develop proper out-to field training program that will help to maintain and furthermore improve nurse's image.